Related by context. All words. (Click for frequent words.) 74 vitro 70 tumorigenicity 68 gene expression 67 murine 67 vitro experiments 66 transcriptional regulation 66 CEACAM1 66 vitro studies 65 preclinical models 65 miRNA expression 65 vimentin 65 biodistribution 65 transgene expression 65 vitro assays 65 orthotopic 65 preclinical studies 64 Annexin V 64 xenograft 64 anti fibrotic 64 TNFa 64 pro angiogenic 64 antitumor 64 biomarker 64 physiologically relevant 64 mRNA expression 64 CTGF 64 mammalian cells 64 osteoblast 64 ERK1 2 64 c MYC 64 HepG2 cells 64 E#F# 64 ex vivo 63 peptide 63 tumorigenesis 63 TLE3 63 preclinical 63 cytotoxicity 63 Immunohistochemical analysis 63 kinase pathway 63 preclinical efficacy 63 selective inhibition 63 syngeneic 63 anti proliferative 63 endothelial cell 63 eNOS 63 IL 1beta 63 miRNA 63 activin 63 cardiac myocytes 63 hepatocyte 63 vitro assay 63 antigenic epitopes 62 effector function 62 biomarkers 62 HER3 62 TNFalpha 62 p# activation 62 Notch1 62 xenograft models 62 RNAi mediated 62 TGF ß 62 HCV replication 62 inhibitory effects 62 neutralizing antibody 62 anti angiogenic 62 intracellular 62 β catenin 62 PC# cells 62 antiangiogenic 62 PGE2 62 inducible 62 mRNA 62 ENaC 62 vascular endothelial cells 62 IL 1ß 62 vivo efficacy 62 survivin 62 experimental autoimmune encephalomyelitis 62 iNOS 62 ENMD # 62 peripheral blood mononuclear 62 BMP signaling 62 gene amplification 62 IFN γ 62 cytokine 62 neuronal differentiation 62 S#A# [002] 62 Tie2 62 immunological 62 Flt3 61 gene expression profiling 61 cultured cells 61 miR #a [001] 61 miR #a [002] 61 adipogenic 61 tyrosine phosphorylation 61 ESBA# 61 hippocampal neurons 61 Nedd4 61 Preclinical studies 61 anti CD3 61 proteoglycan 61 somatostatin 61 HIF 1a 61 IL 1β 61 annexin V 61 GRP# 61 ligand binding 61 Inosine 61 dopaminergic neurons 61 SIRT2 61 novel peptide 61 Kupffer cells 61 EGF receptor 61 immunohistochemical 61 TGF β 61 xenografts 61 P cadherin 61 alveolar epithelial cells 61 c myc 61 S1P 61 NF kappaB activation 61 ligase 61 vivo experiments 61 WT1 61 pharmacodynamic 61 adenoviral 61 HEK# cells 61 H#K#me# 61 microglial 61 keratinocyte 61 siRNA 61 cytoprotective 61 peptides 61 endothelial 61 ERK signaling 61 miRNAs 61 VEGF receptor 61 pharmacodynamic PD 61 vivo preclinical 61 neurotrophic 61 IFN alpha 61 transcriptionally 61 ectopic expression 61 flavopiridol 61 neurotrophic factors 61 microRNA 60 pDCs 60 mouse xenograft 60 intracellular signaling 60 osteogenic 60 transgenic mouse model 60 potent inhibitors 60 oligomerization 60 hTERT 60 isotypes 60 Jhdm2a 60 Rab5 60 microglial activation 60 autophagic 60 IL #E 60 p# INK4a 60 p#NTR 60 PDGFR 60 MAPK 60 biodistribution studies 60 remyelination 60 depsipeptide 60 lysosomal 60 transfected cells 60 HDAC6 60 Clusterin 60 MGMT gene 60 IL #p# 60 overexpression 60 epithelial cell 60 NOD SCID mice 60 trophoblast cells 60 myocyte 60 receptor inhibitor 60 EpCAM 60 caveolin 1 60 antitumoral 60 VE cadherin 60 Smad3 60 splice variants 60 microRNA profiling 60 preclinically 60 nonclinical studies 60 eotaxin 60 cell motility 60 TNF receptors 60 glycosylation 60 GAPDH 60 selective modulator 60 CDK inhibitor 60 recombinant protein 60 UsiRNAs 60 renal fibrosis 60 opioid receptor 60 matrix metalloproteinases 60 enzymatic activity 60 P#X# 60 ribonuclease 60 ON #.Na 60 nAChRs 60 integrins 60 EGFr 60 ZFP TF 60 BMP4 60 potently inhibited 60 glycosylated 60 prostate carcinoma 60 antisense inhibition 60 Foxp3 60 fibrotic disease 60 mTOR inhibitors 60 CCR9 60 intestinal epithelium 60 prostate epithelial cells 60 fibrotic 60 transfected 60 stem cell differentiation 60 siRNA mediated 60 epithelial 60 cathepsin B 60 thioredoxin 60 noncoding RNAs 60 CHO cells 60 nicotinic acetylcholine receptor 60 uPA 60 PK PD 59 FGFR3 59 effector functions 59 Galectin 59 immunohistochemical analysis 59 induces apoptosis 59 proto oncogene 59 small molecule activators 59 inducible nitric oxide synthase 59 carcinoembryonic antigen 59 IFN gamma 59 NOD mouse 59 radiolabeled 59 morphogenesis 59 p# mitogen activated 59 inflammatory cytokine 59 neuronal 59 CD#b 59 mimetics 59 vidofludimus 59 FasL 59 immunofluorescence staining 59 neuroprotective effects 59 small molecule inhibitors 59 organogenesis 59 microRNA expression 59 gastrin 59 pharmacokinetic 59 osteoinductive 59 Stat5 59 mutant SOD1 59 Aurora kinase 59 colon carcinoma 59 Wnts 59 macrophage 59 cAMP signaling 59 #ME# 59 immunomodulatory 59 antiapoptotic 59 neovascularization 59 MAPK pathway 59 MMP# 59 GRK2 59 VEGFb 59 cardiomyocyte 59 Hh pathway 59 PlGF 59 transgenic mouse models 59 morphogen 59 proteolysis 59 GPR# [002] 59 Anticalins ® 59 murine model 59 methylated DNA 59 IGF IR 59 oncoprotein 59 qRT PCR 59 elastase 59 proapoptotic 59 lysate 59 histone acetylation 59 serine protease 59 colorectal tumor 59 SOCS3 59 immunoregulatory 59 virulence genes 59 potent inhibitor 59 CCR2 59 osteoblast differentiation 59 antitumor efficacy 59 ligand 59 TAp# 59 apoptotic cells 59 #T# L1 59 Akt 59 MDSCs 59 signaling pathways 59 molecular biomarkers 59 CXCR4 59 serine threonine kinase 59 induced apoptosis 59 vitro cytotoxicity 59 p# MAPK 59 secretory pathway 59 GLUT4 59 mAb 59 EGFR signaling 59 Rap1 59 nNOS 59 isoforms 59 chemokine receptor 59 constitutively active 59 cMET 59 IGF 1R 59 human hepatocytes 59 autocrine 59 potently inhibit 59 SH2 B 59 isoform 59 neurite outgrowth 59 mitogen activated protein kinase 59 lentiviral vectors 59 neuroprotective 59 follistatin 59 proteolytic cleavage 59 Wnt signaling 59 cell adhesion molecule 59 RRM1 59 immunostaining 59 pericytes 59 sd rxRNA compounds 59 homodimer 59 GM CSF 59 ABCA1 59 VEGF expression 59 P selectin 59 breast cancer metastasis 59 pharmacological 59 nanomolar 59 molecular 59 mediated apoptosis 59 PDGF 59 osteoclast 59 polyamine 59 DNMT1 59 angiogenic 59 electrophysiological 59 tumor vasculature 59 estrogen receptor beta 59 tumor microenvironment 59 tumor antigen 59 intratumoral injection 59 transduce 59 TGF beta1 59 Fc receptor 59 intracellular protein 59 situ hybridization 59 xenograft tumors 59 neuromuscular junction 59 lymphoid cells 59 nutlin 59 apoE 59 fosbretabulin 59 partial agonist 59 bispecific antibody 59 LSI #P 59 HIF PH inhibitors 59 TGF alpha 59 MicroRNA 59 HIF 1alpha 59 dopamine transporter 59 prognostic indicator 59 IGFBP2 59 heterodimers 59 transfection efficiency 59 transgenic mouse 59 inhibition 59 HuR 59 galectin 3 59 FGFR4 59 Eg5 59 E3 ubiquitin ligase 59 umbilical vein 59 cAMP 59 deacetylation 59 neural cells 59 systemically administered 59 RT qPCR 59 humoral 59 immunological responses 59 ligand induced 59 splenocytes 59 allosteric 58 phenotypic 58 ion channel 58 ultrastructural 58 TRPV3 58 apoptotic 58 histopathological 58 hES cells 58 adhesion molecule 58 bone marrow stromal cells 58 situ hybridisation 58 monocytes macrophages 58 mammalian 58 Androgen receptor 58 Wnt beta catenin 58 zebrafish 58 neuroprotection 58 immunoreactivity 58 immune modulation 58 proteinase 58 quantitative PCR 58 proteins 58 neuropilin 58 TGFβ 58 BACE1 58 calpain 58 HSCs 58 AT1R 58 JAK2 58 phenotyping 58 tenascin C 58 mediated inhibition 58 hypoxia inducible factor 58 induce apoptosis 58 cytokines IL 58 transcriptional activation 58 interleukin IL -# 58 HIF 1α 58 branching morphogenesis 58 subtype selective 58 outer membrane proteins 58 antiangiogenic activity 58 matrix metalloproteinase 58 ERK pathway 58 cisplatin resistant 58 binding affinity 58 glycosyltransferase 58 milatuzumab 58 MAP kinase 58 OXi# 58 posttranslational modification 58 MT1 MMP 58 vivo validation 58 haematopoietic 58 adipogenesis 58 subcellular localization 58 immunohistochemical staining 58 estrogen receptor alpha 58 Cytochrome P# 58 plasma kallikrein 58 antiproliferative activity 58 hedgehog pathway 58 HSP# 58 acinar cells 58 pharmacodynamic effects 58 TNFα 58 PTP 1B 58 downregulation 58 transfection 58 phenotype 58 phosphorylated 58 catenin 58 miRs 58 antibody 58 leukocyte recruitment 58 soluble receptor 58 redox active 58 clonogenic 58 histone deacetylase inhibitor 58 hematopoiesis 58 M1 muscarinic 58 TLR8 58 monocyte 58 TIMP 58 DXL# 58 microRNA miR 58 occludin 58 V#F mutation 58 TNFR 58 p# inhibitor 58 peptide antigens 58 inosine 58 gene inactivation 58 Cyclin E 58 mechanistic insights 58 Sgk1 58 quantitative RT PCR 58 immunomodulatory effects 58 vivo RNAi 58 DNA methylation 58 Preclinical studies suggest 58 membrane fusion 58 paxillin 58 FDG PET 58 kinase inhibition 58 inhibitory 58 bone morphogenetic proteins 58 heparan sulfate 58 neuronal cells 58 Hh 58 intracoronary 58 TRAIL induced apoptosis 58 carcinogenesis 58 vivo assays 58 TGF ß1 58 mitochondrial respiration 58 mesenchymal stem cells MSCs 58 TIMP 1 58 prodrugs 58 Akt activation 58 myofibroblasts 58 upregulated 58 glioblastoma cells 58 PI3K Akt 58 ubiquitylation 58 malignant transformation 58 antitumor activity 58 EphA2 58 ß catenin 58 vesicle fusion 58 #ß 58 receptor mediated endocytosis 58 potent inhibition 58 PI3K inhibitor 58 knockout mice 58 DNA demethylation 58 vivo pharmacology 58 chondrocyte 58 ubiquitination 58 Pim kinases 58 cyclophilin D 58 Fas ligand 58 OGG1 58 proteomic analysis 58 Platelet Derived Growth 58 methylation patterns 58 mdx mouse 58 clusterin 58 Western blotting 58 IL #R 58 sGC 58 ChR2 58 pharmacokinetic properties 58 Histone deacetylase 58 Preclinical 58 miR #b [001] 58 CXCL# 58 HBx 58 physiologic 58 PDGF B 58 operon 58 lysates 58 molecularly targeted 58 muscarinic 58 transgenic mice 58 GSOs 58 interferon IFN 58 epithelial mesenchymal transition 58 adipose derived stem cells 58 nucleolin 58 FGFs 58 cells overexpressing 58 cell transplantation 58 Secretase 58 myocardial tissue 58 podocytes 58 MMP9 58 pharmacodynamic parameters 58 antibody mediated 58 TTR gene 58 EZN 58 radiosensitivity 58 Hepatocytes 58 siRNA knockdown 58 pharmacokinetics 58 MyoD 58 58 annexin 58 FK# 58 NF kB pathway 58 TRO# 58 prostanoid 58 homodimers 58 cell lysis 58 replicon 58 paracrine 58 humoral immune responses 58 tumor cells 58 soluble CD# 57 ubiquitin ligase 57 #F FDG 57 endothelial activation 57 Symadex 57 inhibitory receptor 57 hematopoietic progenitor cells 57 degranulation 57 FKBP# 57 tumorigenic 57 humoral antibody 57 small molecule 57 IKKß 57 CXCR7 57 TLR9 57 histone modifications 57 vasculature 57 transcriptional repressor 57 E1A 57 antitumor effect 57 tumor hypoxia 57 VSV G 57 antitumor effects 57 chemoresistance 57 tetramer 57 myogenesis 57 sd rxRNA 57 microRNAs 57 PBMCs 57 atherogenesis 57 beta1 integrin 57 serotonin receptor 57 oncomodulin 57 polypeptide 57 CagA 57 cynomolgus monkeys 57 Lodamin 57 secreted protein 57 immunofluorescence 57 mucosal 57 costimulation 57 immunomodulation 57 phosphorylation 57 CD1d 57 STAT3 57 CCL# 57 antiproliferative effects 57 MMP2 57 BAL# [001] 57 HCV protease 57 lung fibroblasts 57 cyclooxygenase 2 57 oncogenic 57 endosomal 57 neuroprotective properties 57 prognostic markers 57 factor PlGF 57 microsomal 57 constitutively expressed 57 inhibited tumor 57 pharmacologic 57 PDGF receptor 57 isoenzymes 57 myocytes 57 COX2 57 apoptosis inducing 57 erythropoiesis 57 NOD mice 57 hypermethylation 57 Cytotoxic T 57 PXD# 57 lung fibrosis 57 MTT assay 57 GRN#L 57 Smoothened 57 Immunohistochemical 57 CGEN # 57 TSLP 57 CCR3 57 Cx# [001] 57 protein tyrosine kinase 57 transferrin receptor 57 ligases 57 siRNA therapeutic 57 oncoproteins 57 STAT1 57 spermatogenesis 57 metalloproteinases 57 CD# ligand 57 sphingosine 1 57 infantile NCL 57 LPS induced 57 CB2 receptor 57 neuronal dysfunction 57 PKCi 57 pleiotropic 57 Overexpression 57 RQ PCR 57 CD#L 57 cells transfected 57 Upregulation 57 ImmunoVEX HSV2 57 immunotoxin 57 membrane protein 57 miR# 57 F actin 57 MUC1 57 γδ T cells 57 FGF# 57 H#K# [002] 57 glucagon receptor 57 1ß 57 γ secretase 57 CHD5 57 FoxO1 57 constitutively 57 Runx2 57 pathophysiological effects 57 IGFBP 3 57 transactivation 57 dephosphorylation 57 eIF4E 57 Wnt signaling pathway 57 #beta estradiol 57 PEGylated 57 hMSCs 57 microvascular endothelial cells 57 proinflammatory mediators 57 Sphingomab 57 pyruvate kinase 57 TRIOLEX 57 vascularization 57 hematopoietic 57 bioluminescence imaging 57 iroxanadine 57 Smurf1 57 vivo imaging 57 receptor mediated 57 E3 ligase 57 GRNCM1 57 upregulation 57 plasma pharmacokinetics 57 gut mucosa 57 heterologous 57 endogenous 57 DNA methyltransferases 57 targeting CD# 57 adenosine receptor 57 thymidylate synthase TS 57 costimulatory 57 polypeptides 57 NFkB 57 C1q 57 mouse xenograft models 57 MAb 57 bioluminescent imaging 57 APOPTONE 57 cytokine interleukin 57 CFTR protein 57 PPARγ 57 cartilage regeneration 57 Th# 57 cytosolic 57 therapeutically relevant 57 collagenase 57 OMP #M# 57 CD# receptor 57 Kv#.# 57 confocal microscopy 57 imetelstat 57 Preclinical Study 57 RNA polymerases 57 muscarinic receptors 57 TLR7 57 apolipoproteins 57 melanocortin receptors 57 anti inflammatory cytokine 57 cathepsins 57 interleukin 1ß 57 chemosensitivity 57 mTOR 57 bleomycin 57 pharmacodynamic properties 57 vivo potency 57 pharmacodynamics 57 neuronal cell 57 RANKL 57 cerebrospinal fluid CSF 57 transcriptomes 57 poly ADP ribose polymerase 57 tau phosphorylation 57 Mcl 1 57 interleukins 57 PKC delta 57 upregulate 57 overexpressing 57 beta globin gene 57 NFkappaB 57 adhesion molecules 57 Kahalalide F 57 metabolomic profiling 57 plasminogen 57 humanized antibody 57 mitogenic 57 LRP5 57 potent antitumor activity 57 HOTAIR 57 cells hESCs 57 cytokine secretion 57 c Src 57 HDAC inhibitor 57 calcineurin 57 p# Shc 57 glucocorticoid receptor 57 NMDA receptor 57 potent antiproliferative 57 EGFR receptor 57 pancreatic islet 57 bile acid 57 phosphate S1P 57 integrin 57 oncogenic transformation 57 downregulated 57 DHFR 57 CD# expression [001] 57 substrate specificity 57 TLR2 57 PECAM 1 57 neurturin 57 tumor suppressor protein 57 anti atherogenic 57 Homspera 57 pRb 57 luciferase 57 busulfan 57 neurotrophic factor 57 4E BP1 57 #HT#A 57 signaling pathway 57 prostaglandin synthesis 57 Onconase 57 β1 57 MMPs 57 cultured neurons 57 KLF4 57 vascular disrupting agents 57 pro apoptotic 57 transduced 57 macrophage infiltration 57 F FDG PET 57 glucocorticoid 57 splice variant 57 gastric carcinomas 57 phosphatases 57 cytotoxic 57 Wnt#b 57 epithelia 57 ERa 57 factor G CSF 57 EGFR 57 viral kinetics 57 apical membrane 57 tumor angiogenesis 57 cortical neurons 57 telomerase reverse transcriptase 57 neuronal nitric oxide synthase 57 p#Kip# 57 oral bioavailability 57 IAP inhibitor 57 siRNAs 57 nicotinic receptor 57 mitogen 57 adipocyte differentiation 57 mononuclear 57 epithelial tissue 57 FUS1 57 osteoblastic 57 adrenoceptor 57 BMAL1 57 motor neuron degeneration 57 druggable targets 57 Xenograft 57 Rb#/p# 57 favorable pharmacokinetic 57 Aβ 57 PTP1B 57 ß1 57 tumor metastasis 57 KSP inhibitors 57 cytokeratin 57 immune modulating 57 photoreceptor 57 endothelial nitric oxide synthase 57 perivascular 57 Neurotrophic Factor 57 antiviral potency 57 glial 57 MDR1 57 signaling cascades 57 erythropoietic 57 beta catenin 57 innate immune responses 57 acyltransferase 57 liver fibrosis 57 Six3 57 aberrantly activated 57 FGF signaling 57 transmembrane protein 57 upregulates 56 intracellular signaling pathways 56 intratumoral 56 protein tyrosine phosphatase 56 motoneurons 56 mRNAs 56 hepatocytes 56 polyclonal 56 XL# inhibits 56 ACh 56 pharmacodynamic endpoints 56 orally dosed 56 proteases 56 HDACi 56 AMACR 56 coexpression 56 ^ sup #m 56 eIF2 56 adipose cells 56 cholesterol efflux 56 GPR# [001] 56 NKT cell 56 NKG2D 56 UCP2 56 peroxidase 56 thyroid hormone receptor 56 ncRNA 56 prolyl 56 methyltransferase 56 PET imaging 56 CaM 56 CDK inhibitors 56 nuclease 56 mutational analysis 56 IgG1 56 JAK2 enzyme 56 HBV replication 56 Th2 cytokines 56 p#INK#a 56 biomarker discovery 56 anti angiogenic agent 56 endotoxemia 56 Id1 56 hematopoietic cells 56 kinase 56 microRNA biomarkers 56 p# alpha [001] 56 nanomolar range 56 P gp 56 CD# [002] 56 catabolism 56 thrombin receptor 56 Pichia pastoris 56 heparanase 56 phosphorylate 56 sCD# 56 Src kinases 56 galectins 56 small molecule agonists 56 androgen receptor AR 56 membrane proteins 56 Lp PLA 2 56 monoclonal 56 TGF beta 56 immune responses 56 potent inducer 56 shRNA 56 CBLC# 56 LDL receptor 56 β amyloid 56 ultrastructure 56 telomerase activation 56 microvascular 56 matrix metalloproteases 56 supernatants 56 cellular cytotoxicity 56 cytokine IL 56 bioactivity 56 PARP inhibition 56 radiolabeled antibodies 56 HER2/neu 56 phagocytosis 56 BCL2 56 PEGPH# 56 cystic fibrosis transmembrane conductance 56 kinase domain 56 myogenic 56 β 56 Leydig cells