Related by context. All words. (Click for frequent words.) 74 vitro experiments 71 Preclinical studies 68 preclinical studies 67 preclinical efficacy 67 selective inhibition 66 CCR9 66 vivo 66 preclinical models 66 vitro cytotoxicity 65 PPARγ 65 CCR2 65 Immunohistochemical analysis 65 vivo experiments 65 ENMD # 64 antiproliferative effects 64 rBChE 64 vitro 64 xenograft models 64 peroxidase 64 GRNCM1 64 inhibitory effects 64 vimentin 64 preclinically 64 CGEN # 64 potent inhibitors 64 immunized mice 64 pan HDAC inhibitor 63 fosbretabulin 63 flavopiridol 63 antitumor effects 63 neurotrophic 63 Lodamin 63 OXi# 63 pharmacokinetic studies 63 orally dosed 63 TNFa 63 kallikrein 63 tumorigenicity 63 murine model 63 histone deacetylase inhibitor 63 induce apoptosis 62 induces apoptosis 62 pharmacodynamic properties 62 oxysterols 62 antigenic epitopes 62 solithromycin 62 INGN 62 xenografts 62 oral prodrug 62 inosine 62 antiviral activity 62 S/GSK# 62 Factor VIIa 62 nonclinical studies 62 Preclinical Study 62 PSN# [002] 62 PLX cells 62 OMP #M# 62 depsipeptide 62 NOD mouse 62 matrix metalloproteases 62 cytotoxin 62 NOD mice 62 vivo efficacy 62 potent inhibitor 62 immunohistochemical 62 FK# 62 immunohistochemical analysis 62 anticancer activity 62 activin 62 transgenic mouse models 62 GPx 62 interferon IFN 62 SIRT2 62 nanoviricides 62 transgenic mouse model 62 small molecule inhibitors 62 Lp PLA 2 62 antiangiogenic activity 62 laboratory experiments 61 potent inhibition 61 cardioprotective effects 61 Multimeric 61 antisense inhibition 61 PTHrP 61 Homspera 61 GFT# 61 neuroprotective properties 61 mRNA expression 61 cultured cells 61 anti proliferative 61 pegylated 61 pegylated liposomal doxorubicin 61 CDK inhibitor 61 xenograft 61 retapamulin 61 antitumor activity 61 mimetics 61 HepG2 cells 61 anti CD3 61 c MYC 61 cytotoxicity 61 Eg5 61 muscarinic 61 forskolin 61 miR #a [001] 61 microglial activation 61 annexin V 61 pDCs 61 agonism 61 small molecule defensin 61 plasma pharmacokinetics 61 mTOR inhibitors 61 Valortim R 61 riociguat 61 murine 61 Angiolix 61 Xanafide 61 peripheral blood mononuclear 61 benfotiamine 61 TLE3 61 HIF PH inhibitors 61 LT NS# 61 PI3K inhibitor 61 antiproliferative activity 61 favorable pharmacokinetic profile 61 outer membrane proteins 61 biochemical assays 61 IL 1β 61 immunological responses 60 huC# DM4 60 HDAC inhibitors 60 EGF receptor 60 peptide antigens 60 TNFalpha 60 antitumor 60 PPARgamma 60 transcriptional regulation 60 uricase 60 antitumor effect 60 situ hybridization 60 selective modulator 60 Symadex 60 adult mesenchymal stem 60 BAL# [001] 60 E#F# 60 Elvitegravir 60 vitro assays 60 delafloxacin 60 Panzem 60 Thiovir 60 S1P 60 Interferon Beta 60 virulence genes 60 BioVant 60 p# inhibitors 60 hepatoma 60 upregulation 60 GAP #B# 60 Clusterin 60 HCV protease 60 sulindac 60 cytoprotective 60 antisense oligonucleotide 60 adenoviral 60 TRO# 60 Palifosfamide 60 vitro assay 60 potent anticancer 60 immunotoxins 60 IL #E 60 pro angiogenic 60 neutralizing antibody 60 Pentraxin 2 60 Cytochrome P# 60 glucocorticoid receptor 60 cDNAs 60 HDACi 60 HCV replicon 60 Onconase 60 selective inhibitors 60 promoter methylation 60 β1 60 LB# [003] 60 murine models 60 mouse xenograft models 60 syngeneic 60 pharmacodynamic PD 60 novel VDA molecule 60 APOPTONE 60 nucleoside analogues 60 bile acid 60 Preclinical studies suggest 60 Aurora kinase 60 serine protease 60 LRP6 60 TRAIL induced apoptosis 60 decitabine 60 immunomodulatory 60 immunoblotting 60 MGd 60 FUS1 60 act synergistically 60 bleomycin 60 fumagillin 60 geldanamycin 60 PEG SN# 60 antitumoral 60 Recombinant Human 60 pharmacokinetic parameters 60 hypermethylation 60 orally bioavailable 60 Carfilzomib 59 p# activation 59 Kupffer cells 59 selectively inhibits 59 miRs 59 overexpressing 59 antitumor efficacy 59 SERMs 59 EGFRvIII 59 ZFN modified 59 Cyclin E 59 systemically administered 59 MDR1 59 NOD SCID mice 59 Six3 59 Sphingomab 59 IFN gamma 59 microRNA miR 59 Genotypes 59 anticancer agent 59 ERK1 2 59 antagomirs 59 inhibit tumor 59 differentially expressed genes 59 gastrin 59 mertansine 59 LY# [002] 59 IL 1beta 59 anti angiogenic 59 nelfinavir 59 radiolabeled 59 oral bioavailability 59 immune modulation 59 paricalcitol 59 phosphatases 59 CORT # 59 RRM1 59 novel peptide 59 E. faecalis 59 #ME# 59 meropenem 59 IFN alpha 59 cytokines IL 59 receptor subtypes 59 CA4P 59 PolyMedix defensin 59 fluvastatin 59 alkylating agent 59 PXD# 59 Antitumor 59 PEGylated 59 Radilex 59 trastuzumab Herceptin ® 59 inhibitor RG# 59 Tß4 59 neuroprotective 59 Etoposide 59 HCV replication 59 somatostatin 59 GSK3B 59 anti fibrotic 59 IGFBP2 59 antiangiogenic 59 seliciclib 59 partial agonists 59 HER3 59 alkaline phosphatase ALP 59 iNOS 59 immunostaining 59 Cardiomyocytes 59 CXCR2 59 monomeric 59 GHRH 59 Sym# 59 CXCR7 59 CTGF 59 XL# inhibits 59 kDa protein 59 FGFR 59 immunohistochemical staining 59 mice lacking 59 MEK inhibitor 59 Inosine 59 SGLT2 59 polymerase inhibitor 59 MTHFR 59 TLR3 59 genes encoding 59 calcitonin 59 orally administered inhibitor 59 preclinical 59 oral JAK1 59 Dr. Pasinetti 59 Monoclonal Antibody 59 XmAb# 59 DFMO 59 IGFBP 3 59 potently inhibited 59 eotaxin 59 TSP1 59 immunomodulatory effects 59 PARP inhibition 59 antisense inhibitor 59 elacytarabine 59 TB4 59 polymerase inhibitors 59 cidofovir 59 mediated apoptosis 59 resolvin 59 DermaVir 59 immunomodulatory properties 59 bexarotene 59 TPI ASM8 59 cisplatin resistant 59 JAK inhibitor 59 5alpha reductase 59 AEG# 59 Phase Ib clinical trials 59 alveolar epithelial cells 59 milatuzumab 59 Pharmacokinetics PK 59 GM CSF 59 parthenolide 59 potent antitumor activity 59 olaparib 59 active moiety 59 neuroprotective effects 59 PD LID 59 erythropoietic 59 PS# [001] 59 immunofluorescence staining 59 CTAP# Capsules 59 Aliskiren 59 LPA1 receptor 58 INCB# [001] 58 serotonin synthesis 58 mecamylamine 58 substrate specificity 58 androgen receptor AR 58 deacetylation 58 IGF IR 58 JAK1 58 RGB # 58 Interferon alpha 58 cyclic peptide 58 CCR1 58 liposomal formulation 58 radiolabeled TM# 58 anti leukemic 58 immunoreactivity 58 investigational humanized monoclonal antibody 58 GPR# [002] 58 targeting CD# 58 vidofludimus 58 lipoic acid 58 cMET 58 prucalopride 58 DNA intercalator 58 receptor inhibitor 58 transfected 58 histone deacetylase inhibitors 58 neuropilin 58 TLR8 58 plasma kallikrein inhibitor 58 IgG1 58 Calcitonin 58 bactericidal activity 58 RANKL 58 ganetespib 58 rifamycins 58 thioredoxin 58 Pharmacokinetic PK 58 posaconazole 58 PlGF 58 PCK# 58 Pegylated 58 antitumour activity 58 enzyme inhibitors 58 BMS# 58 ZFP TF 58 bioluminescence imaging 58 transgene expression 58 probiotic strain 58 vivo validation 58 humoral antibody 58 immunomodulation 58 GRP# 58 interleukin IL -# 58 interleukins 58 Kahalalide F 58 #D#C# 58 tyrosine phosphorylation 58 overexpression 58 eNOS 58 MUC1 58 neurotrophic factors 58 busulfan 58 proteomic analysis 58 masitinib 58 EpCAM 58 Cytotoxic T 58 cytochrome P 58 RNA antagonist 58 silymarin 58 Protelos 58 chemopreventive agent 58 small molecule activators 58 angiogenesis inhibitor 58 TRIOLEX 58 EZN 58 FLT3 58 Debio 58 Irinotecan 58 PDGF B 58 peptide fragments 58 intravesical 58 Enzastaurin 58 NS4A 58 Apoptone 58 demonstrated antitumor activity 58 HER2/neu 58 toxicological studies 58 P#X# 58 PDGFR 58 GLP toxicology studies 58 IL 1ß 58 Anticalin ® 58 HDACs 58 adipogenic 58 protein encoded 58 HIF PHI 58 vascular disrupting 58 hTERT 58 erlotinib Tarceva ® 58 NMDA receptor antagonists 58 induced apoptosis 58 secretin 58 glioblastoma cells 58 Lp PLA2 58 potently inhibits 58 chitinase 58 Nedd4 58 cyclophilin D 58 sequence homology 58 mitogen activated protein kinase 58 A3 adenosine receptor 58 neuroregenerative 58 collagenase 58 anti angiogenic agent 58 FGFR2 58 ADAGIO study 58 Darinaparsin 58 nanomolar 58 glucose lowering 58 anti amnesic 58 phosphate S1P 58 orthotopic 58 monoclonal 58 CXCR4 58 potently inhibit 58 #I TM# 58 PKCi 58 TGF ß 58 genotoxicity 58 Aplidin 58 HDAC Inhibitor 58 redox active 58 tipifarnib 58 JAK inhibitors 58 isotypes 58 triterpenoids 58 CCX# 58 PBMCs 58 amprenavir 58 IGF 1R 58 humanized monoclonal 58 NEUGENE 58 histone acetylation 58 ImmunoVEX HSV2 58 serum antibody 58 Overexpression 58 herpesviruses 58 mechanistic insights 58 bone marrow stromal cells 58 potent anti angiogenic 58 protein kinase inhibitor 58 N Myc 58 HIF 1α 58 pharmacokinetic interactions 58 bovine thrombin 58 HBx 58 constitutively active 58 TTR gene 58 aurora kinase 58 Pharmacokinetic studies 58 placebo controlled studies 58 CHO cells 58 ocular formulation 58 DiLA2 58 58 histone deacetylase HDAC inhibitor 58 Ampligen ® 58 TNF α 58 vorinostat 58 S#A# [002] 58 cynomolgus monkeys 58 mGluR2 NAM 58 CagA 58 gamma tocotrienol 58 Afatinib 58 endostatin 58 idraparinux 58 NKX#.# 58 trastuzumab Herceptin R 58 myo inositol 58 chemokine receptors 58 Bone Morphogenetic Protein 58 ALV# 58 Granulocyte Colony Stimulating Factor 58 receptor antagonists 58 p# MAPK 58 pleiotropic 58 vascular disrupting agent 57 polyamines 57 serine proteases 57 ELISPOT 57 missense mutations 57 epidemiologic studies 57 receptor tyrosine kinase inhibitor 57 splice variants 57 immunostimulatory 57 REP# 57 gene polymorphisms 57 downregulation 57 ANG# 57 mdx mouse 57 neuronal differentiation 57 immunomodulator 57 Oncogene 57 synthetic peptide 57 davunetide intranasal AL 57 trodusquemine 57 APTIVUS 57 placebo controlled clinical trials 57 p# mitogen activated 57 PKC isoforms 57 attenuated strain 57 triphosphate 57 #ß 57 constitutively expressed 57 transcriptionally 57 subgroup analyzes 57 non nucleoside 57 BiTE antibodies 57 Wnt signaling pathway 57 HMG CoA reductase inhibitors 57 oncolytic virus 57 alagebrium 57 PC# cells 57 effector function 57 EGFR HER2 57 elastase 57 ritonavir boosted 57 Bortezomib 57 radiosensitivity 57 antifibrotic 57 immunoglobulin G 57 nucleoside 57 uPAR 57 ESBA# 57 HGS ETR1 57 #beta 57 dose proportionality 57 peroxisome proliferator activated 57 CBLC# 57 VEGFb 57 KLF4 57 PGE2 57 protein tyrosine phosphatase 1B 57 #F FDG PET 57 adenovirus vectors 57 Bifidobacterium 57 Viprovex 57 MEK inhibitors 57 sphingosine 1 57 chemopreventive 57 naturally occurring molecule 57 Amplimexon 57 prostaglandin synthesis 57 synthetic peptides 57 vascular disrupting agents 57 Belerofon 57 antisense oligonucleotides 57 Immunohistochemical staining 57 TIMP 1 57 torezolid 57 RANTES 57 HIF 1a 57 cytostatic 57 pharmacodynamic effects 57 GLYX 57 PKC# 57 RhuDex ® 57 iroxanadine 57 Antiviral Activity 57 HSP# inhibitor 57 cell lysis 57 multicenter Phase II 57 colorectal tumors 57 JAK Inhibitor 57 IL #R 57 butyrylcholinesterase 57 gamma secretase inhibitors 57 Seliciclib 57 viral kinetics 57 orthologs 57 NFκB 57 annexin 57 selective agonist 57 LSI #P 57 SGS# 57 sorafenib Nexavar 57 ASC J9 57 CYT# potent vascular disrupting 57 CD# monoclonal antibody 57 microtubule targeting 57 hypoxia inducible factor 57 antidepressant efficacy 57 trastuzumab Herceptin 57 transgenic rats 57 factor G CSF 57 Squalamine 57 intravenous bisphosphonates 57 entinostat 57 potent antiviral 57 intratumoral injection 57 LPS induced 57 synthetic analogues 57 transmembrane receptor 57 murine monoclonal antibody 57 indibulin 57 nucleosides 57 Valortim ® 57 Anti Tumor Activity 57 PTP 1B 57 quantitative RT PCR 57 phosphorylates 57 Superoxide 57 Epidermal Growth Factor Receptor 57 telomerase activation 57 UsiRNAs 57 Viprovex TM 57 Lpathomab 57 teriparatide 57 antisense inhibitors 57 enzyme inhibitor 57 AMD# [003] 57 HDAC inhibition 57 amino acid substitutions 57 gefitinib Iressa 57 Presents Preclinical Data 57 Annexin V 57 HIF 1alpha 57 Upregulation 57 GRASPA ® 57 TNFα 57 MMP# 57 Phylogenetic analyzes 57 aberrantly activated 57 factor receptor FGFR 57 mouse xenograft 57 Locked Nucleic Acid LNA 57 IFN beta 57 isoenzymes 57 multi kinase inhibitor 57 pharmacodynamic profile 57 inducible 57 antibody fragment 57 inhibitory activity 57 raltegravir 57 rifamycin 57 binding affinity 57 CANCIDAS 57 plasminogen 57 supernatants 57 NITD# 57 inhibitory effect 57 enkephalin 57 Factor Receptor 57 mediated inhibition 57 tenascin C 57 bioactivity 57 tumorigenic 57 interferon γ 57 retaspimycin 57 TLR2 57 Estrogen Receptor 57 NPD1 57 PEDF 57 Liposomal 57 TAp# 57 PDE1 57 Dapagliflozin 57 ^ sup #m 57 ON #.Na 57 proteolytic 57 HDAC inhibitor 57 glucocorticoid 57 p#NTR 57 Inhibitor 57 Lrp5 57 WT1 57 alpha interferon 57 pro apoptotic 57 MAPK 57 miRNA expression 57 proteasome inhibitors 57 glycosylation profile 57 TLR7 57 purified protein 57 Abl 57 proteinase 57 Posiphen 57 Mutagenesis 57 hepatocyte 57 AAV2 57 chemotherapeutic drug 57 alpha7 57 MVA BN R 57 diabetic rats 57 osteoinductive 57 monocytes macrophages 57 replicon 57 2 methoxyestradiol 57 proteases 57 Hedgehog pathway 57 thrombin receptor 57 caspofungin 57 isoforms 57 nicotinamide 57 ADAMTS# 57 immunomodulating 57 pharmacokinetic PK 57 ALN TTR# 57 AMPK activators 57 FasL 57 thrombopoietin 57 PROCHYMAL 57 GRN#L 57 IL #p# 57 pertuzumab 57 Interferon alfa 57 Immunohistochemistry 57 lipoxygenase 57 clusterin 57 neuroprotectant 57 adipose derived stem cells 57 Her2/neu 57 factor TNF 57 remyelination 57 endotoxemia 57 PRT# 57 PSMA ADC 57 RhuDex 57 TG# [003] 57 partial agonist 57 Traficet EN 57 colon carcinoma 57 T#I [002] 57 inhibits protein synthesis 57 explants 57 immune modulatory 57 gene amplification 57 pDC 57 lentiviral vector 57 Chemokine Receptor 57 lymphoid cells 57 tumor specific antigen 57 dexamethasone Decadron 57 ganciclovir 57 inducible nitric oxide synthase 57 siRNAs targeting 57 BNC# 57 antiviral potency 57 radezolid 57 HepDirect prodrug 57 soluble receptor 57 pathophysiological effects 56 Polymorphisms 56 osteoblast 56 ABCB1 56 immunohistochemistry IHC 56 Natural S equol 56 IFN α 56 small molecule agonists 56 Tβ4 56 proto oncogene 56 antiapoptotic 56 hpSCs 56 experimentally induced 56 tumor regression 56 Placebo Controlled Trial 56 osteoclast 56 lenalidomide Revlimid R 56 Fc fusion protein 56 cediranib 56 cytokine receptor 56 plasma kallikrein 56 VA# [002] 56 lysophosphatidic acid 56 Bendavia 56 HER2 receptor 56 pancreatic adenocarcinoma 56 antisense compounds 56 minocycline 56 cytokine IL 56 PDE#A 56 berberine 56 gene encoding 56 P selectin 56 gemcitabine Gemzar 56 TGF beta1 56 Tyrima 56 Panzem R 56 colorectal carcinoma 56 Hepatocytes 56 histone modifications 56 neuroimaging studies 56 TMEM#B 56 menadione 56 monoclonal anti 56 antidiabetic 56 thymosin 56 apoE 56 azacytidine 56 Rab5 56 PRTX 56 MAPK pathway 56 nucleoside analog 56 Pin1 56 apoptotic pathway 56 rhBMP 2 56 proteoglycan 56 gene inactivation 56 Anticalins ® 56 mycophenolate mofetil 56 HDAC 56 bronchial epithelial cells 56 selective antagonist 56 Lactobacillus reuteri 56 zoledronate 56 microglial 56 LC#m# 56 urothelial cancer 56 GPR# [001] 56 glycosylated 56 micronuclei 56 VEGF receptor 56 amifostine 56 carcinoembryonic antigen 56 CEACAM1 56 thymidylate synthase TS 56 matrix metalloproteinases 56 stable nucleic acid 56 HuMax EGFr 56 pharmacokinetic characteristics 56 Hsp# inhibitor 56 mapatumumab 56 PKC delta 56 bone morphogenetic protein 56 miR #a [002] 56 methylated DNA 56 immunofluorescence 56 Lactoferrin 56 follistatin 56 PI3K Akt 56 huN# DM1 56 imetelstat 56 genotoxic 56 CALGB 56 siRNA knockdown 56 Phase 2a trial 56 fosamprenavir 56 dinucleotide 56 tryptase 56 molecular biomarkers 56 dephosphorylation 56 avidin 56 randomized trials 56 multicenter trials 56 TLK# 56 meta analyzes 56 lipid particles 56 bendamustine 56 SRT# [003] 56 biodistribution 56 CRLX# 56 urocortin 56 HQK 56 coexpression 56 iPSC 56 mTOR mammalian target 56 poly ADP ribose polymerase 56 selective inhibitor 56 antiangiogenesis 56 IgM antibody 56 MORAb 56 Cellastim 56 polyamine 56 Hedgehog signaling 56 GAD# 56 K ras mutations 56 Tacrolimus 56 cells MSCs 56 Runx2 56 5 HT6 receptor 56 Lacromin 56 Cytotoxicity 56 dexpramipexole 56 miR #b [001] 56 nAChR 56 acinar cells 56 Cyclosporine 56 eprotirome 56 immune stimulatory 56 HDAC6 56 safety tolerability pharmacokinetic 56 strontium ranelate 56 benzimidazole 56 topical formulations 56 NexACT 56 NMDA antagonist 56 glucagon receptor 56 Th# cells 56 Pharmacokinetic 56 Mucosal 56 intravenous dosing 56 vascular endothelial cells 56 CCL# 56 Azedra 56 lymphocyte counts 56 MenSCs 56 protein tyrosine kinase 56 elvitegravir 56 MAPCs 56 hematopoietic 56 highly immunogenic 56 Teriflunomide 56 biochemical abnormalities 56 Guanilib 56 AMACR 56 intravenously administered 56 acetylcholinesterase 56 sodium glucose cotransporter 56 PC3 cells 56 Azacitidine 56 tolerability profile 56 administered subcutaneously 56 VAPRISOL 56 aromatase 56 MAGE A3 56 IgG antibodies 56 chlamydial 56 Hsp# Inhibitor 56 M1 muscarinic 56 MAGE A3 ASCI 56 proteasome inhibitor 56 Corynebacterium 56 Exherin TM 56 FGFR4 56 vivo preclinical studies 56 fluticasone furoate 56 fulvestrant 56 pRb 56 hydroxylase 56 JAK2 inhibitors 56 inhibitor celecoxib 56 SABCS 56 PDE4 inhibitor 56 homodimers 56 thalidomide Thalomid 56 sulodexide 56 physiologically relevant 56 rHuEPO 56 antiandrogens 56 deacetylase inhibitors 56 immunotoxin