upregulated

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(Click for frequent words.) 76 overexpressed 75 downregulated 73 phosphorylated 72 mRNA expression 72 mitogen activated protein kinase 70 CXCL# 70 constitutively expressed 70 catenin 69 iNOS 69 overexpression 69 overexpress 69 Overexpression 69 mice lacking 69 proto oncogene 69 ERK1 2 69 upregulation 69 TNFalpha 68 CagA 68 transduced 68 immunoreactivity 68 cell adhesion molecule 68 overexpressing 68 autophagic 68 DNMT1 68 MMP2 68 IL 1β 68 phosphorylates 68 vascular endothelial cells 67 isoforms 67 phosphorylate 67 inducible nitric oxide synthase 67 constitutively active 67 vimentin 67 HepG2 cells 67 genes encoding 67 PDGFR 67 transfected 67 potent inhibition 67 induces apoptosis 67 glycosylated 67 matrix metalloproteinases 67 c MYC 67 induce apoptosis 67 IL 1beta 67 VCAM 1 67 deficient mice 66 RhoA 66 CD#b 66 MAPK 66 S#A# [002] 66 Kupffer cells 66 MAP kinase 66 4E BP1 66 downregulation 66 FOXO3a 66 WT1 66 caveolin 1 66 antiproliferative activity 66 E cadherin 66 hypermethylation 66 regulated kinase ERK 66 IFN gamma 66 caveolin 66 proinflammatory cytokines 66 PTHrP 66 AMACR 66 Akt 66 homozygotes 66 β catenin 66 Immunohistochemical analysis 66 STAT1 66 constitutively 66 upregulates 66 heterozygotes 66 TIMP 66 ERBB2 66 ErbB4 66 activin 66 mitogenic 65 Notch1 65 ADAM# 65 carcinoembryonic antigen 65 p# MAPK 65 Rho kinase 65 protein encoded 65 GSTP1 65 homodimers 65 hTERT 65 serine protease 65 eNOS 65 IL 1ß 65 PTPN# 65 E#F# 65 mRNA 65 FasL 65 aberrantly activated 65 TGF ß1 65 alveolar epithelial cells 65 cell adhesion molecules 65 ß catenin 65 cytosolic 65 TrkA 65 erythrocytes 65 monocyte 65 ectopic expression 65 somatostatin 65 induced apoptosis 65 VEGF receptor 65 virulence genes 65 inducible 65 nitric oxide synthase 65 eotaxin 65 1alpha 65 IGFBP 65 Macrophage 65 tryptase 65 adhesion molecule 65 Smad3 65 activating mutations 65 serine threonine kinase 65 miR #b [001] 65 metalloproteinase 65 Activating mutations 65 HIF 1alpha 65 inhibitory effects 64 hypoxia inducible factor 64 downregulates 64 catalytic subunit 64 gene encoding 64 lysosomal 64 serine threonine 64 ERK signaling 64 EphB4 64 MAPK pathway 64 phosphatidylinositol 64 Rap1 64 Rab5 64 Foxp3 64 enzymatic activity 64 casein kinase 64 receptor gamma 64 murine 64 androgen receptor AR 64 interleukins 64 CEACAM1 64 survivin 64 osteocalcin 64 LPS induced 64 Phosphorylation 64 nAChR 64 miRNA genes 64 tyrosine kinase 64 K + ATPase 64 TMEM#B 64 uPAR 64 pRb 64 phosphorylation 64 miR #b [002] 64 HER2 neu 64 IFN γ 64 proapoptotic 64 coactivator 64 protein kinase C 64 receptor tyrosine kinase 64 RUNX3 64 cyclooxygenase COX 64 isoenzyme 64 clusterin 64 GTPase 64 potent inhibitor 64 pDCs 64 Upregulation 64 GRP# 64 miR #a [001] 64 TNFa 64 PI3K Akt 64 potent inhibitors 64 BMP2 64 ubiquitinated 64 deacetylation 64 transcriptional activation 64 synthase 64 MUC1 64 matrix metalloproteinase 64 isoform 64 acetylcholine receptor 64 extracellular signal 64 perivascular 64 mediated apoptosis 64 dephosphorylation 64 claudin 64 phosphoprotein 64 transactivation 64 amino terminal 64 H#K# methylation 64 transmembrane protein 64 differentially regulated 64 microglial 64 Akt1 64 phosphatidylinositol 3 64 polyamine 64 acyl CoA 64 mRNAs 64 miR# 64 gene polymorphism 64 cyclooxygenase 64 osteoblast 64 TGF β 64 GAPDH 64 CCR2 64 differentially expressed 64 monocyte chemoattractant protein 64 adenylate cyclase 64 transfected cells 64 LNCaP cells 64 homodimer 64 VE cadherin 64 CDK4 64 potently inhibited 64 CCR7 64 plasmacytoid dendritic cells 64 tyrosine phosphorylation 64 heme oxygenase 1 64 ENaC 64 Mice lacking 64 intestinal epithelial cells 64 5 hydroxytryptamine 64 Sp1 63 matrix metalloproteinases MMPs 63 cytosol 63 MTHFR 63 Clusterin 63 PGC 1α 63 BMP signaling 63 hypermethylated 63 ER alpha 63 ERa 63 FGFR4 63 LDL receptor 63 lipoxygenase 63 TNFR 63 CCR9 63 cyclin D1 63 HER2 HER2 63 cathepsin B 63 Dysregulation 63 promoter methylation 63 pro angiogenic 63 encodes protein 63 BRAF V#E 63 RRM1 63 63 signaling pathway 63 STAT3 63 autocrine 63 H#K#me# 63 HDAC2 63 elastase 63 astrocytic 63 p#NTR 63 cotransporter 63 NKG2D 63 TGF ß 63 synthetase 63 decarboxylase 63 HIF 1a 63 hydroxylase 63 bcl 2 63 transcriptional repressor 63 ERalpha 63 cardiac fibroblasts 63 isoprostane 63 1beta 63 neurturin 63 transferase 63 heterodimers 63 intercellular adhesion molecule 63 63 chemokine receptor 63 evolutionarily conserved 63 cathepsins 63 alpha subunit 63 lymphoid tissue 63 IL #p# 63 eosinophils 63 AT1R 63 p#Kip# 63 cytokine interleukin 63 beta catenin 63 gene encodes 63 HIF 1α 63 proinflammatory 63 null mice 63 anaphase promoting complex 63 NKX#.# 63 wildtype 63 5 lipoxygenase 63 VEGFR2 63 extracellular domain 63 inhibitory receptor 63 Supplementary Fig 63 selective modulator 63 GSTM1 63 cyclins 63 P selectin 63 lymphoid cells 63 paracrine 63 BACE1 63 GLI1 63 COL#A# 63 myocyte enhancer factor 63 RASSF1A 63 c MET 63 tyrosine hydroxylase 63 nNOS 63 thioredoxin 63 63 p# activation 63 PP2A 63 antisense inhibition 63 acetylated 63 Caveolin 1 63 myocyte 63 epithelia 63 Raf MEK ERK 63 selective agonist 63 monocyte chemotactic protein 63 interferon IFN 63 RANKL 63 overexpressing cells 63 mutant p# 63 serotonin receptor 63 nM 63 anti inflammatory cytokine 63 PPARg 63 endoplasmic reticulum 63 selectively inhibited 63 63 Flt3 63 VIPR2 63 factor HGF 63 neurofilament 63 tenascin C 63 CCL# 63 CYP# [002] 62 E selectin 62 heme oxygenase 62 aggrecan 62 xenograft tumors 62 receptor kinase 62 receptor blocker 62 CD# CD# 62 leptin receptor 62 hepatic lipase 62 EGFP 62 acyltransferase 62 immunoreactive 62 Wnt 62 myofibroblasts 62 estrogen receptor alpha 62 tropomyosin 62 epithelial cells lining 62 Runx2 62 cytokeratin 62 CaM 62 dimerization 62 Cyclin E 62 Bcl XL 62 methylenetetrahydrofolate reductase 62 glucocorticoid receptor 62 downregulate 62 upregulating 62 cytokine IL 62 glutamic acid decarboxylase 62 histone deacetylases 62 beta subunit 62 receptor subtypes 62 pro inflammatory cytokine 62 midgut 62 syngeneic 62 neuroblastoma cells 62 erythropoiesis 62 plasma membrane 62 cofilin 62 IL #R 62 PON1 62 intronic 62 Cx# [001] 62 constitutively activated 62 receptor subtype 62 CXCL5 62 receptor gene 62 tumor suppressor protein 62 coexpression 62 cAMP 62 oncoprotein 62 cyclin E 62 mediated inhibition 62 GRK2 62 valine 62 KIT mutations 62 5 HT1A 62 gene polymorphisms 62 p# mutations 62 BCL2 62 telomerase reverse transcriptase 62 miR #a [002] 62 paxillin 62 adduct 62 ABCA1 62 MLH1 62 Ser# 62 lactate dehydrogenase 62 arginase 62 β 62 TIMP 1 62 chemotactic 62 c myc 62 MMP9 62 transcription factors 62 EZH2 62 pro apoptotic 62 prostaglandin E2 PGE2 62 TGF β1 62 tumor suppressor gene 62 PKC beta 62 kinase pathway 62 glutathione S transferase 62 VEGFR1 62 GSTT1 62 regulates gene expression 62 CXCR2 62 LRP6 62 alveolar macrophages 62 Mcl 1 62 JAK2 enzyme 62 Src kinase 62 inflammatory cytokine 62 leukemic cell 62 MyoD 62 estrogen receptor beta 62 tumorigenesis 62 receptor CXCR4 62 inverse agonist 62 histone 62 cystic fibrosis transmembrane conductance 62 thyroid hormone receptor 62 intestinal epithelium 62 microglial cells 62 TGF alpha 62 pDC 62 TGF beta1 62 TGFβ 62 PGE2 62 caveolae 62 C. albicans 62 sFlt 1 62 hydrolases 62 contractility 62 TNF α 62 RANTES 62 NKT cells 62 TRPV4 62 GLUT1 62 LDLR 62 NFkB 62 AhR 62 ganglioside 62 poly ADP ribose polymerase 62 histone H3 62 β1 62 galactosidase 62 PDE#A 62 transgene expression 62 gastric carcinoma 62 transcription factor 62 HDAC6 62 ErbB2 62 cyclic AMP 62 airway hyper responsiveness 62 PKC delta 62 c KIT 62 C#Y 62 colon carcinoma 62 p# mitogen activated 62 proteases 62 FANCD2 62 antiapoptotic 62 glomerular 62 PIP2 62 chondrocyte 62 TAp# 61 FGF2 61 BMAL1 61 acetylation 61 SNP rs# [001] 61 transmembrane receptor 61 cyclic AMP cAMP 61 CaMKII 61 Abeta# 61 ACh 61 Eg5 61 PIK3CA 61 NADPH oxidase 61 MDM2 61 prostaglandin E2 61 insulin receptors 61 myo inositol 61 mRNA transcripts 61 COX2 61 monocytes 61 FDG uptake 61 tumorigenicity 61 HER2 receptor 61 transcriptional regulation 61 inhibited tumor 61 Hypoxia Inducible Factor 61 CD# receptor 61 missense mutation 61 HMG CoA reductase 61 potent inducer 61 PDGF receptor 61 HOTAIR 61 inhibitory effect 61 proteolysis 61 superoxide dismutase 61 uncoupling protein 61 epithelial 61 IGF1R 61 TrkB 61 transiently 61 rs# [004] 61 cytoplasmic domain 61 isotypes 61 dysregulated 61 rs# [002] 61 adrenergic receptors 61 transmembrane 61 PTP1B 61 Treg cells 61 Ki# 61 fusion protein 61 chemokine 61 c Fos 61 phosphatases 61 acinar 61 estrogen receptor 61 intron 61 PBMCs 61 myeloid derived 61 mice overexpressing 61 receptor molecule 61 adrenal cortex 61 phosphate S1P 61 palytoxin 61 SH2 B 61 defensin 61 IGF 1R 61 mitogen activated protein 61 PAK1 61 RAS RAF MEK 61 p# p# 61 overactivated 61 Elevated serum 61 cardiac myocytes 61 FGFR3 61 ERK pathway 61 JAK2 61 #HT#A 61 intracellular 61 regulated kinase 61 phosphatase 61 interleukin IL 61 methylated 61 pyrimidine 61 FLT3 61 colocalization 61 autoantibody 61 kinase gene 61 ERK activation 61 thrombin receptor 61 Wnt beta catenin 61 interleukin IL -# 61 ubiquitin ligase 61 stromal cells 61 surface glycoprotein 61 motoneurons 61 CD1d 61 thymic 61 Factor VEGF 61 IL8 61 Mice deficient 61 microglial activation 61 apoptotic pathway 61 downregulating 61 palladin 61 MT1 MMP 61 Cytotoxic T 61 interleukin IL -6 61 SIRT2 61 μg ml 61 uPA 61 proximal tubule 61 phospholipase 61 leukocyte adhesion 61 phospho 61 P cadherin 61 subcellular localization 61 muscarinic receptors 61 caspase activation 61 tubulin polymerization 61 POMC neurons 61 Rho GTPase 61 P. gingivalis 61 SCD1 61 nutlin 3a 61 signaling pathways 61 selectively binds 61 Th# cells 61 V#F mutation 61 receptor protein 61 ncRNAs 61 IGFBP2 61 transgenic mice 61 cyclin 61 protein kinase 61 anti proliferative 61 PrP 61 homolog 61 kinase enzymes 61 Tie2 61 neuropeptide Y 61 HER2/neu 61 EGFR protein 61 glutamatergic neurons 61 synovial tissue 61 receptor activation 61 PLA2 61 oncogenic transformation 61 EGFRvIII 61 selectively inhibits 61 rs# [001] 61 cytokine signaling 61 neuronal dysfunction 61 alkaline phosphatase 61 cytoprotective 61 lyase 61 melanocyte 61 effector memory 61 Dpp 61 CD8 cells 61 5HT 61 HBx 61 endothelial nitric oxide synthase 61 apoE 61 adipose cells 61 noradrenergic 61 acetyl CoA 61 proteoglycan 61 knockout mice 61 amyloid β 61 FGFR2 61 adrenoceptor 61 CD#c 61 Pten 61 EF Tu 61 Î ² 61 DLX5 61 PTEN gene 61 receptor agonists 61 cytoplasmic 61 orthologs 61 mesothelin 61 guanosine 61 chemoattractant 61 Immunohistochemical staining 61 metalloproteinases 60 metabolizing enzyme 60 IL# [001] 60 IGF IR 60 S#K# 60 splenocytes 60 cyclin dependent kinase 60 enterocytes 60 MDR1 60 suppressor cells 60 hepatocyte growth 60 bronchial epithelial cells 60 SMAD4 60 ubiquitylation 60 leptin receptors 60 NO synthase 60 HLA DR 60 adenocarcinomas 60 lymphangiogenesis 60 EGFR expression 60 ALDH 60 protein tyrosine kinase 60 GFAP 60 potently inhibits 60 dose dependently 60 c Src 60 oncogenic 60 Akt signaling 60 Stat3 60 LKB1 60 inhibits tumor 60 plasminogen activator inhibitor 60 lymph node metastasis 60 lysophosphatidic acid 60 synuclein 60 kDa protein 60 PAX5 60 cytokine 60 ribosomal protein 60 EGFR gene 60 XL# inhibits 60 Cdc# 60 BH3 60 cholecystokinin CCK 60 EGF receptor 60 dinucleotide 60 cisplatin resistant 60 adducts 60 glioma cells 60 splice variants 60 lymphocyte activation 60 integrins 60 ligand TRAIL 60 mitochondrial respiration 60 epithelial cell 60 fibroblast 60 IGFBP 3 60 Cathepsin B 60 K ras mutations 60 phosphorylase 60 cytokines IL 60 EGFr 60 ^ sup + 60 goblet cells 60 Pin1 60 Fas ligand 60 apoptotic cells 60 bile acid 60 PC# cells 60 hepatocellular carcinomas 60 isomerase 60 postsynaptic 60 Src 60 TLR2 60 XBP1 60 antioxidant enzyme 60 proinflammatory mediators 60 beta amyloid peptide 60 urothelial 60 NR2B 60 NF kappaB activation 60 beta1 integrin 60 oligomerization 60 CYP#B# 60 transmembrane domains 60 AMPA receptor 60 db db mice 60 sortilin 60 nestin 60 Interferon gamma 60 tyrosine kinase receptor 60 SNP rs# [002] 60 EphA2 60 anti apoptotic 60 3'UTR 60 endoplasmic reticulum ER 60 potent stimulator 60 extracellular 60 focal adhesions 60 homeobox gene 60 receptor inhibitor 60 tau protein 60 Nampt 60 Jurkat cells 60 upregulate 60 alpha synuclein protein 60 γ secretase 60 PI3K 60 Histone 60 TNF alpha IL 60 neoplastic cells 60 interferon pathway 60 reductase 60 orthologous 60 TERT 60 alpha1 60 microsomal 60 Protein Kinase C 60 basophils 60 NOTCH1 60 MMPs 60 costimulation 60 forkhead 60 TNFα 60 cytochrome c 60 NMDA N 60 GLUT4 60 Smad7 60 functional polymorphism 60 normal karyotype 60 autoantibodies 60 eIF4E 60 CD8 + 60 homologues 60 substrate specificity 60 cysteine residues 60 glyceraldehyde 3 60 fibronectin 60 dimeric 60 glycosyltransferase 60 bone morphogenetic protein 60 isoenzymes 60 receptor 60 myometrium 60 agonist induced 60 stroma 60 γ 60 Jhdm2a 60 converting enzyme 60 trophoblast cells 60 umbilical vein 60 thrombospondin 60 60 innervated 60 Wnt#b 60 dehydrogenase 60 hepatoma 60 polyadenylation 60 CD# antigen 60 peripheral tissues 60 RAD# [001] 60 partial agonist 60 serine proteases 60 macrophage 60 catalase 60 CTGF 60 endonuclease 60 inflammatory cytokines 60 enolase 60 neurite outgrowth 60 F actin 60 TGF b 60 B7 H1 60 cyclin dependent kinase inhibitor 60 lipopolysaccharide 60 FUS1 60 muscarinic receptor 60 metalloprotease 60 COMT 60 SMN1 60 peroxidase 60 interneurons 60 HDACs 60 Serum concentrations 60 TTR gene 60 striatal 60 costimulatory molecules 60 Wnt1 60 HSP# 60 glycolipids 60 phosphate dehydrogenase 60 hyperactivation 60 bFGF 60 MYCN 60 Kv#.# 60 NAD + 60 transgenic mice expressing 60 acetyltransferase 60 lipoprotein lipase 60 HER3 60 PI3 kinase 60 NFκB 60 TGFb 60 soluble fms 60 HLA DRB1 * 60 KLF4 60 NFkappaB 60 prostate epithelial cells 60 glycated 60 UCP1 60 effector cells 60 epithelial tumors 60 micro RNAs 60 CDKN2A 60 catabolism 60 receptor alpha 60 peroxisomal 60 phosphoinositide 60 lacZ 60 p# protein 60 miRNAs 60 erythrocyte 60 osteoblastic 60 presenilin 60 nicotinic receptor 60 ErbB 60 gastric mucosa 60 cholesterol homeostasis 60 podocytes 60 homologs 60 mutant proteins 60 MSH2 60 ErbB3 60 potentiated 60 TSC1 60 secretory pathway 60 Wnt signaling pathway 60 mediated phosphorylation 60 GNAQ 60 CCL2 60 malignant transformation 60 pro inflammatory cytokines 60 steroidogenic 60 CIB1 60 lipid rafts 60 factor PlGF 60 TGFß 60 cyclic adenosine monophosphate cAMP 60 Hedgehog signaling 60 glutamatergic 60 vWF 60 endometrium 60 hypomethylation 60 CCN2 60 PPARγ 60 SETDB1 59 Rac1 59 tau phosphorylation 59 glucokinase 59 proteins 59 Peyer patches 59 ERCC1 59 colorectal carcinoma 59 secretory proteins 59 chemokine receptors 59 lysyl oxidase 59 telomeric 59 receptor CD# 59 sphingolipid 59 Cyclin D1 59 receptor blockers 59 ChR2 59 hypothalamic pituitary 59 SPINK1 59 serine 59 morphogen 59 proteolytic cleavage 59 cofactor 59 ATPase 59 polypeptides 59 Vps# 59 receptor subunit 59 endocytosis 59 HSF1 59 SMase 59 kinase domain 59 Hedgehog pathway 59 neuronal nitric oxide synthase 59 ovarian carcinoma 59 alkaline phosphatase ALP 59 apolipoprotein B 59 mitogen activated protein kinases 59 GHRH 59 hydrolase 59 heterozygous 59 radiosensitivity 59 laminin 59 adipogenic 59 transcriptional regulator 59 μmol L 59 tunica vaginalis 59 glutamate receptors 59 cystatin 59 MMP# 59 phosphorylated tau 59 HDAC enzymes 59 retinoic acid receptor 59 59 Wnt signaling 59 oligomeric 59 mTOR signaling 59 transthyretin 59 HbF 59 unmutated 59 59 MEK1 59 CD# + [001] 59 NFAT 59 c fos 59 epithelial cells 59 thymidine kinase 59 Gln 59 oncoproteins

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