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(Click for frequent words.) 73 coexpression 72 constitutively active 72 induced apoptosis 72 catenin 71 haematopoietic 71 cyclic AMP cAMP 71 transgene expression 71 F actin 70 mRNA expression 70 ERK signaling 70 transfected cells 70 Fas ligand 70 COL#A# 70 Leydig cells 70 protein tyrosine phosphatase 70 lymphoid cells 70 transcriptional activation 70 antiapoptotic 70 Western blotting 70 CagA 70 TGF ß 70 ribosomal protein 70 Jhdm2a 70 p# alpha [001] 70 transduced 69 hippocampal neurons 69 immunoreactivity 69 peroxidase 69 osteoblast 69 pDC 69 vimentin 69 annexin V 69 methyltransferase 69 glycosylated 69 Histone 69 phosphorylates 69 neurite outgrowth 69 transcriptional repressor 69 Upregulation 69 transferase 69 transgenic mouse models 69 STAT1 69 LPS induced 69 beta actin 69 beta subunit 69 autophagic 69 ERK1 2 69 substrate specificity 69 Microtubule 69 PARP1 69 adipogenic 69 serine threonine 69 ectopic expression 69 Oncogenic 69 mRNA encoding 69 RAS RAF MEK 69 CD# CD# 69 phosphoprotein 68 FGFR3 68 apoE 68 morphogen 68 Rab5 68 oligomeric 68 adipocyte 68 FasL 68 homodimers 68 nitrotyrosine 68 allelic variants 68 PTPN# 68 null mice 68 regulated kinase ERK 68 transmembrane protein 68 Aâ 68 SMAD4 68 TMEM#B 68 CaM 68 alveolar epithelial cells 68 SOCS3 68 Overexpression 68 cyclin E 68 cells transfected 68 sequence homology 68 constitutively expressed 68 beta globin gene 68 microglial 68 calcium homeostasis 68 trophoblast cells 68 NKT cell 68 chondrocyte 68 NKG2D 68 TNFalpha 68 β catenin 68 ciliated 68 CEACAM1 68 secretase 68 CD# expression [001] 68 experimental autoimmune encephalomyelitis 68 carboxyl terminal 68 steroidogenic 68 homodimer 68 ERalpha 68 siRNA knockdown 68 nitric oxide synthase 68 alpha subunit 68 isoenzyme 68 cellular prion protein 68 VE cadherin 68 IL #p# 68 overexpressing 68 subcellular localization 68 Huntingtin 68 M1 muscarinic 68 p#NTR 68 acinar 68 oncogenic transformation 68 colocalization 68 histone acetylation 68 BCL2 68 mRNA transcripts 68 TGF beta1 68 fig. S1 68 intracellular signaling 68 osteoblastic 68 micronuclei 68 tropomyosin 68 Notch1 68 MMP# 68 Amino acid 68 1alpha 68 microsomal 68 PC# cells 68 androgen receptor AR 68 myofibroblasts 68 cytoplasmic domain 68 JAK STAT 68 ESR1 67 CD#c 67 alpha synuclein protein 67 pertussis toxin 67 osteoclast 67 operon 67 umbilical vein 67 MnSOD 67 prostate epithelial cells 67 microglial activation 67 vesicular stomatitis virus 67 phagocytosis 67 glycosyltransferase 67 hepatoma 67 Phosphorylation 67 synuclein 67 serine threonine kinase 67 deacetylation 67 pyrimidine 67 ACh 67 IFN g 67 FKBP# 67 vesicle fusion 67 CYP #D# 67 ligand induced 67 Rap1 67 dimeric 67 Cytotoxic T 67 retinoic acid receptor 67 paxillin 67 Nedd4 67 cathepsin B 67 Arp2 3 67 Corynebacterium 67 thymidylate synthase TS 67 tumorigenicity 67 granzyme 67 cardiolipin 67 inverse agonist 67 hypothalamic pituitary 67 Abeta protein 67 cytidine 67 p#Kip# 67 vascular endothelial cells 67 melanocyte 67 EGFP 67 MT1 MMP 67 acetylcholine receptor 67 differential gene expression 67 prostatic tissue 67 adrenocortical 67 p# MAPK 67 virulence genes 67 HIF 1a 67 striated muscle 67 mice lacking 67 IL6 67 Sertoli cell 67 TIMP 67 factor HGF 67 MMP2 67 renal fibrosis 67 Tubulin 67 peroxidation 67 TGF b 67 miRNA expression 67 glomerular 67 PON1 67 MAPKs 67 C1q 67 CD1d 67 endonuclease 67 PTHrP 67 ventricular myocardium 67 proteolysis 67 adenylate cyclase 67 anaphase promoting complex 67 arachidonic acid AA 67 chromosome condensation 67 gliosis 67 erythrocytes 67 IgG1 67 tyrosine phosphorylation 67 ERBB2 67 dinucleotide 67 amine oxidase 67 4E BP1 67 SMN1 67 normal prion protein 67 E cadherin expression 67 oxidative phosphorylation 67 phospho 67 Cathepsin B 67 lymphangiogenesis 67 BCL#A 67 eNOS 67 SUMOylation 67 ß amyloid 67 oligomerization 67 Annexin V 67 lipoxygenase 67 Secretase 67 chromosomal rearrangement 67 TrkB 67 EF Tu 67 RhoA 67 aggregated Abeta 67 dephosphorylation 67 ligand receptor 67 Polymorphisms 67 TAp# 67 uPAR 66 P2X 66 catalytically active 66 axonal degeneration 66 μ opioid receptor 66 transiently transfected 66 promoter methylation 66 lipopolysaccharide LPS 66 thymidine kinase 66 Smad3 66 Vps# 66 intracellular pH 66 cell adhesion molecule 66 IL #E 66 leptin signaling 66 Aß 66 6S RNA 66 5alpha reductase 66 centromeric 66 MEK1 66 GAPDH 66 somatostatin 66 MDR1 66 p# activation 66 BMAL1 66 deoxy 66 cytopathic 66 transthyretin 66 Fig. 1C 66 hematopoietic progenitors 66 carboxy terminal 66 beta amyloid peptide 66 melanocyte stimulating hormone 66 kDa protein 66 lysates 66 cytosolic 66 polyamine 66 mesangial 66 regulates gene expression 66 mediated inhibition 66 HepG2 cells 66 WNK1 66 Tie2 66 methylated DNA 66 RNA polymerases 66 proteolytic 66 Cytochrome 66 N Myc 66 proteoglycan 66 splenocytes 66 #ß 66 mitogenic 66 lung epithelial cells 66 NF kappaB activation 66 downregulation 66 beta tubulin 66 telomere dysfunction 66 modulatory 66 Fibroblast 66 tryptase 66 degranulation 66 autoregulation 66 β1 66 ADAMTS# 66 HIF 1alpha 66 lacZ 66 MTHFR 66 DNA methylation patterns 66 cyclin dependent kinase inhibitor 66 TXNIP 66 apoptosis pathway 66 vacuolar 66 constitutively 66 PON1 gene 66 Transcriptome 66 glutamyl 66 germline mutations 66 TET2 66 inherited maternally 66 JAK2 enzyme 66 immunoreactive 66 ectodomain 66 metalloproteases 66 N acetyl 66 antiproliferative activity 66 oxidase 66 hnRNP 66 LRP5 66 H#K#me# 66 β cells 66 embryonal carcinoma 66 cytokine signaling 66 proximal tubule 66 selenoproteins 66 p# Shc 66 palytoxin 66 costimulatory 66 anterior pituitary 66 amyloid peptide 66 plasminogen 66 pRb 66 effector function 66 NKX#.# 66 Schematic representation 66 Fig. 4a 66 peritoneal fluid 66 guanosine 66 ß catenin 66 transgenic mouse model 66 Alkaline Phosphatase 66 immunostaining 66 adrenoceptor 66 cysteines 66 mesothelial cells 66 FGFR4 66 hematopoietic progenitor cells 66 immunoblotting 66 gene rearrangements 66 HCV replication 66 fig. S2 66 plasmacytoid dendritic cells 66 mediated apoptosis 66 alternatively spliced 66 Xenopus embryos 66 TGF ß1 66 outer membrane proteins 66 Dpp 66 amyloid deposition 66 renal tubular 66 monogenic 66 pyruvate kinase 66 Abeta# 66 AT1R 66 downregulate 66 potent inducer 66 erythropoiesis 66 mitotic progression 66 Clusterin 66 MAPK pathway 66 carcinoembryonic antigen 66 pancreatic islet 66 dependent protein kinase 66 Sgk1 66 UCP1 66 PrP 66 replicon 66 myocyte 66 cytochrome c oxidase 65 NR2B subunit 65 luciferase reporter 65 EBNA1 65 gene inactivation 65 Protein Kinase C 65 osteoprotegerin 65 mitogen activated protein kinases 65 prostanoid 65 Mesenchymal 65 XBP 1 65 tumoral 65 SIRT2 65 trimeric 65 Alu RNA 65 gamma H2AX 65 pro angiogenic 65 intestinal epithelium 65 NADPH 65 Akt activation 65 Immunohistochemical analysis 65 TGFβ 65 lymphoblasts 65 ATP synthase 65 nitric oxide synthase NOS 65 MAP kinase 65 redox active 65 clonogenic 65 BMP signaling 65 isoenzymes 65 GNAQ 65 MEFs 65 gastric mucosa 65 lymphotoxin 65 deacetylase 65 GSTT1 65 IL 1ß 65 heterochromatic 65 constitutively activated 65 lung epithelium 65 tyrosine kinase receptor 65 cyclase 65 PKC isoforms 65 hyperactivation 65 fibrin deposition 65 P cadherin 65 splice variants 65 Rac1 65 RNA binding 65 hexose 65 proteosome 65 bacterium Escherichia coli 65 ERa 65 obligate intracellular 65 malignant prostate 65 adduct 65 humoral immunity 65 trophoblast 65 prion protein PrP 65 axon guidance 65 ouabain 65 KLF4 65 radiosensitivity 65 clonal expansion 65 serine protease 65 protein conformation 65 DLC1 65 proteolytic activity 65 iNOS 65 uracil 65 caveolin 1 65 Drp1 65 ribosomal DNA 65 lysosomal 65 gene polymorphisms 65 neuronal signaling 65 Fig. 3a 65 pancreatic endocrine 65 PU.1 65 inducible nitric oxide synthase 65 tetramer 65 cystic fibrosis transmembrane 65 #S rRNA gene 65 rRNA 65 FGFs 65 pleiotropic 65 FUS1 65 tumor suppressor protein 65 immunofluorescence staining 65 ncRNA 65 STAT4 65 proteolytic cleavage 65 triacylglycerol 65 hTERT 65 immunofluorescence microscopy 65 rs# [004] 65 aberrantly activated 65 Wnts 65 subcellular compartments 65 β amyloid 65 urate oxidase 65 heterozygotes 65 mitochondrial metabolism 65 E#F# 65 intracellular bacteria 65 beta globin 65 prostaglandin synthesis 65 murine 65 CYP#A# CYP#D# 65 IgG4 65 MDCK cells 65 superoxide dismutase 65 amyloid β 65 endogenous ligands 65 phagocyte 65 chromosomal aberrations 65 adducts 65 bronchial epithelial cells 65 homolog 65 HIF 1α 65 astrocytic 65 RRM1 65 granzyme B 65 cardiac fibroblasts 65 antioxidant enzyme 65 neurofibrillary 65 coding genes 65 osteogenic 65 Fc receptor 65 PrPSc 65 Leydig cell 65 activin 65 PDGF receptor 65 bone morphogenic protein 65 DNMT1 65 miR #a [001] 65 histone modification 65 cAMP signaling 65 IFN γ 65 HUVEC 65 ERK activation 65 myo inositol 65 induces apoptosis 65 receptor kinase 65 ABCB1 65 tubule 65 mucins 65 immunodeficient mice 65 GPI anchored 65 angiotensinogen 65 CpG island 65 cystic fibrosis transmembrane conductance 65 chromosomal DNA 65 fig. S4 65 keratinocyte 65 hemoglobin molecule 65 stably transfected 65 #β estradiol 65 transactivation 65 metalloproteinase 65 Foxp3 65 histone methylation 65 mononuclear cells 65 MTT assay 65 cardiac myocytes 65 PKD1 65 cell adhesion molecules 65 TGF alpha 65 intercellular signaling 65 ubiquitinated 65 podocytes 65 adrenal cortex 65 corpus luteum 65 RNase L 65 innate immune responses 65 BRAF protein 65 vascular endothelial 65 neural progenitor 65 protease activated 65 posttranslational modification 65 motor neuron degeneration 65 adipose cells 65 Genetic variation 65 pituitary hormone 65 postsynaptic 65 myogenesis 65 fascin 65 monomeric 65 epithelia 65 RQ PCR 65 65 synovial cells 65 Akt phosphorylation 65 SOD1 protein 65 PPARg 65 Rho GTPases 65 synaptic transmission 65 monocytic 65 tumor suppressor proteins 65 histone H4 65 Purkinje cell 65 5 HT1A 65 mitogen activated protein kinase 65 SOD2 65 neurofilament 65 assay detects 65 aggrecan 65 STAT3 signaling 65 cultured hippocampal neurons 65 CD#b 65 immunodominant 65 quantitative trait loci 65 fucose 65 p# subunit 65 gene polymorphism 64 lactate dehydrogenase 64 ERK2 64 inhibin B 64 intestinal mucosa 64 immunohistochemical analysis 64 Akt signaling 64 T#M 64 mesenchymal cells 64 actin binding 64 DNA demethylation 64 hypoxia inducible factor 64 Extracellular 64 upregulates 64 syngeneic 64 transmembrane 64 DGAT1 64 cytokine receptor 64 cotransporter 64 murine model 64 γ secretase 64 messenger ribonucleic acid 64 syntaxin 64 c Fos 64 metabolic enzymes 64 PAX5 64 Myostatin 64 pyrimidines 64 Nampt 64 nephron 64 microvessel 64 oncoprotein 64 perivascular 64 transcriptionally 64 Stromal 64 IL 1β 64 ε 64 gamma globin gene 64 gene locus 64 occludin 64 lymphocyte activation 64 protein fragment 64 Cadherin 64 S nitrosylation 64 decarboxylase 64 Sp1 64 pathophysiological effects 64 transfected 64 HOTAIR 64 CCL# 64 Epstein Barr Virus EBV 64 beta. 64 transcriptional regulation 64 peroxynitrite 64 proto oncogene 64 demethylase 64 nucleolar 64 G6PD 64 posttranslational modifications 64 deletion mutant 64 CD8 + 64 induced phosphorylation 64 C3 convertase 64 acyl CoA 64 Estrogen Receptor 64 KCNE2 64 fast skeletal troponin 64 chaperone proteins 64 overactivation 64 TRPV4 64 thymidine 64 TRAIL induced apoptosis 64 cyclin B1 64 monocyte 64 isoforms 64 exocytosis 64 Xenopus laevis 64 TRAF6 64 nucleoli 64 phosphatidylinositol 64 missense mutations 64 Aβ 64 selective inhibition 64 proapoptotic 64 mitochondrial respiration 64 porphyrins 64 NO synthase 64 Phenotypic 64 Histone deacetylase 64 condensin 64 Fig. 3A 64 missense mutation 64 PBMCs 64 sphingomyelin 64 lymphocytic 64 thrombospondin 64 JAK STAT signaling 64 enzymatic activity 64 nucleases 64 ubiquitylation 64 CCR1 64 binding affinities 64 dioxygenase 64 microvessel density 64 cytotoxicity assays 64 PHD2 64 nucleated cells 64 PDE1 64 TMPRSS2 ERG fusion 64 cofilin 64 suppressor gene 64 methylation patterns 64 beta adrenergic receptors 64 ribonucleoprotein 64 Macrophage 64 Prolactin 64 TIMP 1 64 reductase 64 TSC1 64 glycolipid 64 functional polymorphism 64 Heterozygous 64 tumor suppressor PTEN 64 DNA adducts 64 FGF signaling 64 phospholipase 64 breast epithelial cells 64 HSF1 64 R#W [002] 64 Htt 64 intermediate filaments 64 IFN ß 64 myofibroblast 64 metalloprotease 64 1α 64 Figure 1C 64 multinucleated 64 LDLR 64 Hypoxia Inducible Factor 64 NRF2 gene 64 E3 ligase 64 copper zinc superoxide 64 OCT4 64 CCR5 delta# 64 paralogs 64 Fig. 1A 64 microRNA #a 64 LXRs 64 matrix metalloproteinases 64 mutant p# 64 extracellular signal 64 GLUT4 64 1beta 64 toxic beta amyloid 64 calcineurin 64 hypermethylated 64 enkephalins 64 Notch receptor 64 neoplastic cells 64 cis regulatory 64 LRAT 64 exocrine glands 64 Pgp 64 RUNX3 64 JNK1 64 RANTES 64 hemorrhage necrosis 64 transferrin receptor 64 genotoxic stress 64 mTOR signaling pathway 64 B lymphocyte 64 mesenchymal cell 64 CYP#B# 64 STAT3 activation 64 disulfide bond 64 NMDAR 64 glycolytic 64 SH2 domain 64 FGF2 64 Cyclin D1 64 ^ sup ^ 64 membrane permeability 64 circulating endothelial 64 ligand binding 64 metabolite concentrations 64 phosphatases 64 leucocytes 64 PPARγ 64 5 HT2A serotonin 64 frameshift mutation 64 lysate 64 GABAergic interneurons 64 synthases 64 VEGF expression 64 Hedgehog signaling 64 HER2 HER2 64 site directed mutagenesis 64 phosphatase 64 constitutive activation 64 eIF2 64 chemotactic 64 thyrotropin 64 heterodimers 64 posttranslational 64 apolipoproteins 64 motoneurons 64 ultrastructural 64 potent inhibition 64 TGF β 64 cisplatin resistant 64 oligodendrocyte 64 avidin 64 neurotrophin 64 antigenic epitopes 64 Cytoplasmic 64 cytokine receptors 64 immunostimulatory 64 downregulates 64 SNP rs# [001] 64 BRAF V#E 64 HFE gene 64 quinone 64 #S rRNA 64 xenograft tumors 64 annexin 64 phenotypic expression 64 fibrotic disease 64 P selectin 64 nicotinamide adenine dinucleotide 64 glucocerebroside primarily 64 NOD SCID mice 64 cofactor 64 actin polymerization 64 genes encode proteins 64 germinal center 64 fatty acid oxidation 64 PI3K signaling 64 thymic 64 amyloidogenic 64 secretory pathway 64 HepDirect prodrug 64 metabolizing enzyme 64 steroidogenesis 64 caspase activation 64 upregulating 64 GATA3 64 ribosomal RNA 64 bone morphogenetic proteins 64 caveolin 64 plasma fibrinogen 64 proteinase 64 dipeptide 64 Skeletal muscle 64 Catenin 64 GPx 64 VEGFR1 64 PDGFR 64 glycosylation 64 selectively inhibited 64 GABAergic 64 surfactant protein 64 Histologic 64 phosphoinositide 64 glycogen synthesis 64 KIAA# 64 monocyte chemotactic protein 64 ganglioside 64 fig. S# 64 SGK1 64 stem cell pluripotency 64 estrogen receptor beta 64 JCV 64 leukemic cell 64 intergenic regions 64 serum PTH 64 primordial germ cells 63 retinal ischemia 63 triggers apoptosis 63 ERK pathway 63 ERK phosphorylation 63 MSH2 63 triiodothyronine 63 Activating mutations 63 matrix metalloproteinases MMPs 63 prostaglandin E 63 inhibitory effects 63 fluorescently labeled 63 Apc 63 inducible 63 inhibitory receptor 63 TNFa 63 LIS1 63 tau phosphorylation 63 phosphorylate 63 exocrine 63 sarcomere 63 lymphocyte proliferation 63 hydrogenase 63 soluble CD# 63 E3 ubiquitin ligase 63 acetylated 63 MYCN 63 alkaline phosphatase 63 Flt3 63 HLA molecules 63 potently inhibited 63 chromatin remodeling complex 63 acetyltransferase 63 activating mutation 63 COOH terminal 63 upregulate 63 Elevated serum 63 BALB c 63 c MYC 63 kinase domain 63 neuroligins 63 enzymatic pathways 63 glucosides 63 lysophosphatidic acid 63 mitochondrial enzyme 63 photosystem II 63 naturally occurring molecule 63 Hh pathway 63 OGG1 63 paternally inherited 63 plasminogen activator 63 adipocyte differentiation 63 hematopoetic 63 inflammatory cytokine 63 sGC 63 mutated protein 63 beta amyloid proteins 63 colony stimulating factor 63 lipid accumulation 63 proteolytic processing 63 K ras mutations 63 soluble TNF receptor 63 glutamic acid decarboxylase 63 HepG2 63 hematoxylin eosin original 63 GLI1 63 prognostic significance 63 microRNA expression 63 Kir#.# 63 anti inflammatory cytokine 63 mediated phosphorylation 63 Dehydrogenase 63 phosphorylated tau 63 anti CD3 63 Src kinase 63 Aromatase 63 Hepatocytes 63 At#g# 63 diffusible 63 peroxisomal 63 receptor subtypes 63 Smad4 63 neuregulin 1 63 glycolipids 63 tyrosine hydroxylase 63 ligases 63 Cre recombinase 63 HER2 HER3 63 arterial calcification 63 TP# gene 63 Bacteroides 63 protein biosynthesis 63 acetylcholinesterase AChE 63 posterior cingulate 63 PGC 1α 63 glucokinase 63 factor PlGF 63 synaptogenesis 63 plasmid encoding 63 ribonucleotide reductase 63 equimolar 63 eicosanoid 63 metabolomic profiles 63 antibody mediated 63 forkhead 63 glycolytic pathway 63 cholesterol homeostasis 63 granule cells 63 Nod1 63 proinflammatory mediators 63 IGF1R 63 heterologous expression 63 IRE1 63 aminobutyric acid 63 excitotoxic 63 genetic polymorphism 63 p# p#