Related by context. All words. (Click for frequent words.) 66 thromboembolic 66 thromboembolic events 65 thromboembolism 65 Erythropoietic therapies may 64 thrombotic events 63 hyperkalemia 63 atherothrombotic 63 fibrotic 62 torsades de pointes 62 fibrinolytic 62 hepatotoxicity 62 atherosclerotic 62 vasospasm 61 cerebral ischemia 61 left ventricular dysfunction 61 venous thrombosis 60 thromboembolic disease 60 extrapyramidal symptoms 60 myocardial infarction stroke 60 myocardial infarction MI 60 torsade de pointes 60 pericardial effusion 60 hypercalcemia 60 myocardial ischemia 59 antiphospholipid syndrome 59 tumor lysis syndrome 59 cholecystitis 59 myocardial infarction 59 upper gastrointestinal bleeding 59 postoperative AF 59 platelet activation 59 thromboembolic complications 59 subclinical hypothyroidism 59 venous thromboembolism 59 cerebral infarction 59 periprocedural 59 acute coronary syndromes ACS 59 microvascular disease 59 β blockers 59 ischemic complications 59 pheochromocytoma 59 arterial thromboembolic events 59 vasodilatory 59 angina pectoris 59 nephrotoxicity 58 LVSD 58 renal dysfunction 58 vesicoureteral reflux 58 cardioembolic stroke 58 spinal cord compression 58 colorectal adenoma 58 cardiac conduction 58 artery stenosis 58 occlusive disease 58 thrombosis 58 ABCB1 58 diabetic kidney 58 acute coronary 58 hyperprolactinemia 58 IL 1ß 58 ischemic 58 ventricular arrhythmia 58 inflammatory mediators 58 cardiac insufficiency 58 urothelial carcinoma 58 unstable angina pectoris 58 atherosclerotic disease 57 intrahepatic 57 cerebral vasospasm 57 left ventricular LV 57 oxidized phospholipids 57 severe hypoglycemic 57 thrombotic complications 57 urolithiasis 57 prothrombotic 57 VAPRISOL 57 left ventricular systolic 57 reinfarction 57 cerebrovascular events 57 Lp PLA 2 57 intracerebral hemorrhage 57 variceal bleeding 57 hemorrhagic complications 57 hemodilution 57 intracranial bleeding 57 revascularisation 57 macrovascular 57 arterial calcification 57 antithrombotic therapy 57 thromboembolic disorders 57 ximelagatran 57 intracerebral 57 recurrent ischemia 57 cardiac toxicity 57 thrombus formation 57 Ischemic 57 recurrent ischemic 56 thrombogenic 56 endometrial carcinoma 56 impaired renal 56 arterial thrombosis 56 rFVIIa 56 venous thromboembolic events 56 abdominal adiposity 56 E selectin 56 Thrombocytopenia 56 venous thromboembolic 56 TNF α 56 B type natriuretic 56 endotoxemia 56 nonfatal MI 56 plasminogen activator inhibitor 56 plasma uric acid 56 microvascular complications 56 cerebral ischemic 56 atherosclerotic lesions 56 rebleeding 56 liver transaminases 56 hypoxemia 56 reperfusion injury 56 fibrinolysis 56 neointimal hyperplasia 56 Hashimoto thyroiditis 56 thyrotoxicosis 56 thrombo embolic 56 recurrent DVT 56 renal fibrosis 56 thrombus 56 cytopenias 56 renal toxicity 56 fibrin deposition 56 cardiovascular ischemic 56 postoperative morbidity 56 Toxicities 56 coronary stenosis 56 Vaprisol 56 Endothelial dysfunction 56 nonalcoholic steatohepatitis NASH 56 glomerular filtration 56 secondary hyperparathyroidism 56 calculi 56 hyperalgesia 56 lactic acidosis 56 primidone 56 neointimal 56 atheroma 56 bronchospasm 56 rhythm disturbances 56 acute aortic dissection 56 Natalizumab 56 pulmonary infiltrates 56 hypoperfusion 56 abnormal uterine bleeding 55 hyperammonemia 55 renal impairment 55 hypomagnesemia 55 hematologic adverse 55 QT prolongation 55 serum phosphate 55 Restenosis 55 nephrotoxic 55 embolic stroke 55 elevated plasma concentrations 55 left ventricular hypertrophy 55 invasive candidiasis 55 intima media thickness 55 tirofiban 55 varices 55 HGPIN 55 TNF antagonist 55 postoperative complication 55 intracoronary 55 angioedema 55 thrombocytosis 55 T2DM 55 Pioglitazone 55 PCa 55 variceal hemorrhage 55 antithrombotic 55 macrovascular events 55 familial hypercholesterolemia 55 bullous 55 tachyarrhythmias 55 pseudoaneurysms 55 atherothrombosis 55 P = .# 55 hyperparathyroidism 55 ventricular remodeling 55 splenic 55 carotid stenosis 55 tamponade 55 ventricular tachyarrhythmia 55 brain natriuretic peptide 55 femoral neck fracture 55 ventricular tachycardia VT 55 IIIa inhibitor 55 overt nephropathy 55 endometrial hyperplasia 55 cardiac dysfunction 55 renal insufficiency 55 cardiogenic shock 55 intestinal polyps 55 hemodynamic instability 55 embolic 55 serotonin reuptake 55 pleural effusions 55 allograft rejection 55 atherogenic 55 CTGF 55 HMG CoA reductase inhibitors 55 proliferative diabetic retinopathy 55 arterial inflammation 55 tHcy 55 ischemic cardiovascular 55 neoplastic 55 acetabular dysplasia 55 simvastatin ezetimibe 55 postoperative pulmonary 55 angiotensin converting enzyme inhibitor 55 vascular inflammation 55 recurrent VTE 55 myopathy rhabdomyolysis 55 adrenal insufficiency 55 renin angiotensin system 55 stratifying patients 55 gastrointestinal perforation 55 ventricular arrhythmias 55 tardive dyskinesia TD 55 hematologic toxicity 55 eNOS 55 ADPKD 55 hypercoagulability 55 neurologic deficits 55 verapamil 55 prolonged QT interval 55 pathogenetic 55 nodal metastasis 55 heparin induced thrombocytopenia 55 severe neutropenia 55 Mitral valve 55 beta blocker therapy 55 metastatic malignant 55 glycoprotein IIb IIIa inhibitors 54 systemic corticosteroid 54 acute coronary syndromes 54 colorectal carcinoma 54 paragangliomas 54 acute ischemic 54 aspirin clopidogrel 54 noncardiac 54 stenoses 54 mucinous 54 euvolemic hyponatremia 54 thrombophlebitis 54 Intracranial 54 dronedarone 54 baroreflex 54 nonischemic 54 Lp PLA2 54 microalbuminuria 54 CYP #A# 54 malperfusion 54 Hypotension 54 clot formation 54 ocular adverse 54 dopaminergic 54 ischemic cerebrovascular 54 fatal myocardial infarction 54 ischemia reperfusion injury 54 hyperglycaemia 54 ICD shocks 54 composite endpoint 54 hypothalamic pituitary adrenal axis 54 syncope fainting 54 peri procedural 54 onset diabetes mellitus 54 acute myocardial infarction AMI 54 mitochondrial toxicity 54 hypersensitivity reaction 54 coagulopathy 54 ST elevation myocardial 54 pathologic 54 angiotensin converting enzyme inhibitors 54 bone marrow suppression 54 postoperative mortality 54 intimal hyperplasia 54 postoperative delirium 54 pro angiogenic 54 bacterial prostatitis 54 cerebrovascular 54 hepatocellular 54 renal scarring 54 aminotransferases 54 TEAEs 54 VT VF 54 subtrochanteric 54 TNFα 54 pulmonary hypertension PH 54 SCr 54 iatrogenic 54 tumoral 54 olmesartan 54 atherogenesis 54 NAGS deficiency 54 esophageal carcinoma 54 intravenous bisphosphonates 54 intracranial aneurysm 54 atrophic gastritis 54 ischemic cardiomyopathy 54 adrenal suppression 54 syncopal 54 LTB4 54 hyperresponsiveness 54 arthropathy 54 coronary revascularization 54 etiologic 54 Torsades de Pointes 54 COX2 54 interstitial pneumonia 54 hepatic cirrhosis 54 dysfunction LVSD 54 gouty arthritis 54 tumor necrosis 54 infarctions 54 beta adrenergic 54 TZDs 54 osteolytic 54 endothelial activation 54 metabolic acidosis 54 pyelonephritis 54 cytoprotective 54 suppurative 54 dysglycemia 54 intracerebral hemorrhage ICH 54 arrhythmias 54 antihypertensive therapy 54 silent ischemia 54 microvascular 54 hypercholesterolaemia 54 bezafibrate 54 venous thromboembolism VTE 54 microvascular dysfunction 54 systemic lupus erythematosus 54 Atherosclerotic 54 EXJADE 54 vWF 54 stable angina 54 fatal arrhythmias 54 receptor subtype 54 polyp recurrence 54 platelet reactivity 54 VTE 54 plaque ruptures 54 seroma 53 isoproterenol 53 nonfatal myocardial infarction 53 distant metastasis 53 atrial arrhythmias 53 severe hypersensitivity reactions 53 cholelithiasis 53 albuminuria 53 lichen planus 53 vasodilators 53 leiomyomas 53 MTHFR 53 inotropic 53 carotid plaques 53 biliary obstruction 53 non valvular atrial 53 urate lowering 53 muscarinic receptors 53 serum triglyceride levels 53 vasodilatation 53 NATRECOR ® 53 loop diuretics 53 CsA 53 alanine aminotransferase 53 diabetic nephropathy 53 fibrosis 53 erythropoietic 53 mycophenolate mofetil 53 platelet inhibition 53 hepatic failure 53 cerebral vascular 53 ischemic stroke 53 indomethacin 53 TMP SMX 53 symptomatic intracranial 53 Ventricular Tachycardia 53 nephropathy 53 cirrhotic patients 53 diabetic gastroparesis 53 STRIDE PD 53 liver metastasis 53 graft occlusion 53 ipsilateral stroke 53 Dronedarone 53 GP IIb IIIa inhibitors 53 anti thrombotic 53 venous thromboembolic disease 53 carotid artery disease 53 serum urate levels 53 lung fibrosis 53 thromboprophylaxis 53 myeloperoxidase 53 inducible nitric oxide synthase 53 postoperative atrial fibrillation 53 microbleeds 53 endothelial dysfunction 53 irbesartan 53 predisposing factor 53 neovascularization 53 mixed hyperlipidemia 53 Proteinuria 53 revascularization procedures 53 IL 1beta 53 anterior temporal 53 nicardipine 53 invasive aspergillosis 53 beta globin gene 53 bacteriuria 53 orthostatic hypotension 53 JAK2 enzyme 53 lumiracoxib 53 hemorrhagic cystitis 53 thrombolytics 53 valvular disease 53 serum parathyroid hormone 53 abnormal clotting 53 Zollinger Ellison syndrome 53 atrial fibrillation AF 53 Acute Coronary Syndrome 53 anticoagulants blood thinners 53 cardiac troponin 53 arterial thrombotic 53 hyperinsulinemia 53 Mitral regurgitation 53 excitotoxic 53 phenytoin 53 airway hyper responsiveness 53 triiodothyronine 53 concomitant medications 53 hydrops 53 hemodynamic 53 unstable angina 53 peptide BNP 53 bypass grafting 53 acute phosphate nephropathy 53 granulomatous 53 HPA axis 53 thrombi 53 necrotizing pancreatitis 53 subclinical atherosclerosis 53 stenosis 53 Angiotensin II 53 QT interval prolongation 53 levodopa induced 53 Amiodarone 53 ileus 53 carotid IMT 53 coronary artery disease 53 thiazolidinedione TZD 53 HF hospitalization 53 HeFH 53 valsartan 53 AA Amyloidosis 53 osteoclastic 53 chronic thromboembolic pulmonary 53 Aß 53 myocardial infarctions 53 CK MB 53 anterior uveitis 53 coinfected patients 53 elevated triglyceride levels 53 hypercalcaemia 53 arrhythmogenic 53 Aldosterone 53 coadministration 53 elevated ALT 53 vagal 53 akinesia 53 hematuria 53 extracranial 53 systemic corticosteroids 53 amyloid β 53 intrathoracic 53 cardiovascular hospitalization 53 intraventricular hemorrhage 53 MIs 53 pericardial effusions 53 systolic hypertension 53 hyperacute 53 thyrotropin 53 lung edema 53 hypersensitivity reactions 53 gastrointestinal GI 53 macroalbuminuria 53 Asymptomatic 53 leucopenia 53 primary hyperparathyroidism 53 stent restenosis 53 parathyroidectomy 53 cTnT 53 adrenalectomy 53 ATACAND 53 platelet aggregation 53 choroidal neovascularization 53 papilledema 53 perioperative complications 53 atherosclerotic cardiovascular 53 retransplantation 53 Unstable angina 53 idraparinux 53 pulmonary exacerbation 53 myoclonus 53 lymphadenopathy 53 nonfatal stroke 53 mTOR inhibitors 53 MACCE 52 aortic regurgitation 52 ARCOXIA 52 urgent revascularization 52 salmeterol HFA MDI 52 Hematologic 52 G6PD deficiency 52 systemic inflammation 52 HIV HCV coinfected 52 ventricular dysfunction 52 gastric cardia 52 metabolic disturbances 52 treatment emergent adverse 52 pharmacologic 52 hemodynamically significant 52 aneurysmal 52 anticlotting 52 cell lymphoma ALCL 52 deep vein thromboses 52 antiarrhythmic 52 induce orthostatic hypotension 52 antidiabetic drugs 52 systolic dysfunction 52 anginal 52 hepatorenal syndrome 52 natriuretic peptides 52 cancerous colon polyps 52 antiemetics 52 NMIBC 52 saphenous vein graft 52 antiplatelet agent 52 SSc 52 radicular pain 52 POAG 52 sFlt 1 52 postprocedure 52 hippocampal atrophy 52 cerivastatin 52 variceal 52 non selective NSAIDs 52 recombinant tissue plasminogen 52 vaso occlusive crisis 52 coxibs 52 alpha blocker 52 cerebrovascular accidents 52 decompensation 52 stable angina pectoris 52 desvenlafaxine succinate 52 antiplatelet medications 52 thrombocytopenic 52 membranous nephropathy 52 hormone aldosterone 52 dysmotility 52 immune dysregulation 52 cardiotoxicity 52 stenting 52 parecoxib 52 nonfatal myocardial infarction MI 52 hormone angiotensin II 52 chronicity 52 Ranolazine 52 neurogenic 52 patients undergoing CABG 52 tibolone 52 intracranial hemorrhage ICH 52 superficial femoral 52 elevated homocysteine 52 urothelial cancer 52 leukotriene pathway 52 IGFBP 3 52 primary aldosteronism 52 Lupus nephritis 52 optic neuropathy 52 vasoconstriction 52 γ secretase 52 aortic insufficiency 52 plasma kallikrein 52 cyclooxygenase 2 52 bladder dysfunction 52 myocardial infarction ventricular fibrillation 52 parkinsonism 52 atheroma volume 52 GISTs 52 aortic stenosis 52 leukotriene 52 leukopenia 52 gastric varices 52 glomerular 52 angiotensin II receptor blockers 52 Zollinger Ellison Syndrome 52 vertebral fracture 52 cystic lesions 52 atherothrombotic disease 52 inflammatory cascade 52 thoracic aortic 52 patients undergoing percutaneous 52 pancreas pancreatitis 52 synovial 52 prostaglandin D2 52 myocardial 52 airway constriction 52 clopidogrel 52 hemolytic 52 intracranial stenosis 52 PCNSL 52 hypertrophic 52 androgen deficiency 52 cerebrovascular accident 52 eplerenone 52 dysrhythmias 52 apoC III 52 QTc interval 52 androgen deprivation 52 LV dysfunction 52 supine hypertension 52 creatine kinase MB 52 serum IGF 52 Major Adverse Cardiac 52 generalized seizures 52 renin angiotensin aldosterone 52 arterial hypertension 52 intraventricular 52 haematologic 52 lumbar disk herniation 52 potassium sparing diuretics 52 IL6 52 mitral regurgitation 52 amyloid deposition 52 contrast induced nephropathy 52 refractory ischemia 52 infective endocarditis 52 ischemic vascular 52 neurocognitive outcomes 52 SSRI SNRI 52 proteinuria 52 Critical limb ischemia 52 hypercalciuria 52 cirrhotic 52 heparins 52 ventricular fibrillation VF 52 lactate dehydrogenase 52 acute decompensation 52 airway hyperresponsiveness 52 post thrombotic syndrome 52 capillary leak 52 TNFalpha 52 hyperhomocysteinemia 52 neurohormonal 52 radiotherapy RT 52 vWD 52 antiplatelet agents 52 Subarachnoid hemorrhage 52 recurrent miscarriage 52 angiotensin converting enzyme 52 hydronephrosis 52 hepatic encephalopathy 52 TNF blocker therapy 52 Myocardial infarction 52 paroxetine Paxil 52 antithrombotics 52 persistent pulmonary hypertension 52 intracerebral haemorrhage 52 APOE e4 52 alteplase 52 unfavorable cytogenetics 52 tricuspid regurgitation 52 metachronous 52 AT1R 52 efferent 52 hepatocellular carcinoma HCC 52 Pulmonary embolism 52 Doxil ® 52 Stent thrombosis 52 lymph node metastasis 52 severe exacerbations 52 LHRH agonists 52 NYHA Class II 52 antiplatelet medication 52 diabetes mellitus DM 52 coronary artery stenosis 52 IFN beta 52 Pseudomonas aeruginosa infections 52 restenosis reblockage 52 atrioventricular valve 52 nitrotyrosine 52 atherosclerosis 52 atrial tachyarrhythmias 52 hypotensive 52 IIIa inhibitors 52 LVNC 52 bronchial hyperresponsiveness 52 liver fibrosis 52 venous insufficiency 52 obstructive coronary 52 gastrointestinal GI bleeding 52 vasoconstrictor 52 grade cervical intraepithelial 52 interstitial pneumonitis 52 muscarinic 52 neurologic dysfunction 52 anti fibrotic 52 Sjögren syndrome 52 obstructive CAD 52 Leydig cell 52 Candesartan 52 heart arrhythmias 52 knee osteoarthritis OA 52 intra abdominal abscess 52 pruritic 52 glitazones 52 antiplatelet therapy 52 tryptase 52 NFkB 52 antiarrhythmic drugs 52 hypervolemic hyponatremia 52 carotid plaque 52 serum triglycerides 52 thrombolytic agents 52 cryptogenic 52 cardiovascular 52 Avandia Actos 52 serum calcium 52 ezetimibe simvastatin 52 immune thrombocytopenic purpura ITP 52 elevated blood glucose 52 vasoactive 52 von Willebrand disease 52 somatostatin analogs 52 ADHF 52 mesenteric 52 lamotrigine 52 infarct size 52 neuropsychiatric adverse 52 rs# [004] 52 unstable angina UA 52 proinflammatory cytokines 52 RVOT 52 adenomatous 52 reoperations 52 nonvertebral fracture 52 leukoencephalopathy 52 macrovascular disease 52 distal embolization 52 delayed CINV 52 neurotoxicity 52 cardiomyopathies 52 laropiprant 52 malabsorptive 52 false lumen 52 idarubicin 52 PPAR γ 52 de ath 52 Celebrex celecoxib 52 elevated triglycerides 52 thoracic aortic aneurysm 52 gastroduodenal 52 Severe hypoglycemia 52 definite stent thrombosis 52 NT proBNP 52 ß blockers 52 platelet inhibitor 52 CRBSI 52 cTnI 52 aspartate aminotransferase AST 52 ischemia driven 52 Fas ligand 52 thrombus aspiration 52 embolization 52 carcinoid tumor 52 apoptotic cell 52 stroke transient ischemic 52 Abciximab 52 eosinophilic 52 PsA 52 cartilage degeneration 52 systemic toxicity 51 Vasopressin 51 fulminant 51 pT3 51 dyslipidemia 51 systemic hypotension 51 coronary atherosclerosis 51 cardiovascular thrombotic 51 distensibility 51 pleural fluid 51 APTIVUS r 51 rufinamide 51 nocturnal hypoglycemia 51 symptomatic VTE 51 benazepril 51 papillary thyroid carcinoma 51 hypoventilation 51 nonalcoholic steatohepatitis 51 malignant neoplasms 51 serum BDNF 51 aneurysm rupture 51 antihypertensives 51 inotropes 51 anastomotic leak 51 autoantibody levels 51 esophageal 51 bone resorption 51 intra arterial 51 pathophysiologic 51 microglial activation 51 Atrial 51 infarcts 51 prognostic significance 51 hypothalamic pituitary 51 intravesical therapy 51 MGUS 51 IPAH 51 unknown etiology 51 thromboses 51 AST ALT 51 gastric carcinoma 51 neurological manifestations 51 cardiac troponin T 51 pseudoaneurysm 51 HbA 1c levels 51 vasopressor 51 vertebral compression fractures 51 impaired hepatic 51 Dasatinib 51 myelosuppression 51 vasogenic edema 51 nonmelanoma skin cancers 51 Unstable Angina 51 antiarrhythmic drug 51 postoperative bleeding 51 Hydroxyurea 51 extrahepatic 51 idiopathic thrombocytopenic purpura 51 cardiac biomarkers 51 iNOS 51 von Willebrand factor 51 serum homocysteine 51 sirolimus eluting stents 51 chemotherapy induced neutropenia 51 oral anticoagulants 51 Barrett esophagus BE 51 bosentan 51 haemodynamic 51 advanced adenomas 51 angina chest 51 postsurgical 51 progressive dyspnea 51 hyperglycemia 51 hypopituitarism 51 chloride secretion 51 coagulation factors 51 cardiovascular hospitalizations 51 autophagic 51 LRP5 51 cyclin E 51 aplastic anemia AA 51 anticlotting drugs 51 thromboxane A2 51 cardiac valvulopathy 51 vascular permeability 51 LMWH 51 BYSTOLIC 51 thiazide diuretic 51 severe asthma exacerbations 51 neurologic disorder 51 soluble CD# ligand 51 proliferator activated receptor 51 peritumoral 51 atherothrombotic events 51 corticosteroid therapy 51 toxic megacolon 51 postoperative hemorrhage 51 neurologic complications 51 B7 H3 51 coagulation cascade 51 elevated uric acid 51 binary restenosis 51 asymptomatic carotid stenosis 51 CHD CVD 51 Pulmonary hypertension 51 factor TNF 51 perioperative mortality 51 serum urate 51 grade glioma 51 abdominal aortic 51 PAOD 51 neurologic symptoms 51 percutaneous interventions 51 mitral insufficiency 51 osteopontin 51 dopaminergic therapy 51 intracranial hypertension 51 pg ml 51 serum creatinine levels 51 prednisone prednisolone 51 stent implantation 51 6R BH4 51 elevated LDL cholesterol 51 prostate cancer CaP 51 ventricular tachyarrhythmias 51 T1DM 51 recurrent myocardial infarction 51 CVD mortality 51 neoplasm 51 Venous thromboembolism 51 preoperative PSA 51 underlying pathophysiology 51 hsCRP levels 51 aortic valve stenosis 51 afterload 51 plasma triglycerides 51 dobutamine 51 GnRH agonists 51 vascular occlusion 51 infusional 51 chronic pancreatitis CP 51 urine NGAL 51 anti apoptotic 51 noncardiovascular 51 eotaxin 51 ouabain 51 demyelination 51 Parkinson Disease PD 51 atrioventricular 51 pulmonary artery banding 51 vascular reactivity 51 serum biomarker 51 pneumonectomy 51 recurrent atrial fibrillation 51 heterozygous FH 51 renal artery stenosis 51 bivalirudin 51 recanalization 51 myocardial infarct 51 LV hypertrophy 51 mitogenic 51 repolarization 51 subependymal giant cell 51 thiazide 51 hyperphenylalaninemia HPA due 51 Prehypertension 51 gastro oesophageal reflux 51 myofibroblasts 51 blood clotting 51 duodenal 51 ST Segment Elevation 51 metaplasia 51 diabetes dyslipidemia 51 hemorrhagic strokes 51 proinflammatory 51 post surgical adhesions 51 clopidogrel Plavix 51 intact parathyroid hormone 51 nadolol 51 cholestasis 51 pulmonary dysfunction 51 vasculopathy 51 cardiac fibrosis 51 aldosterone 51 Vidaza azacitidine 51 disc degeneration 51 Intussusception 51 MULTAQ 51 atherosclerosis narrowing 51 coronary artery dissection 51 lipid lowering drugs 51 mediastinal 51 severe hypoglycaemia 51 hyperplasia 51 neurocognitive deficits 51 preserved ejection fraction 51 endothelialization 51 hepatic glucose production 51 cardiac hypertrophy 51 cyclooxygenase 51 advanced adenoma 51 vestibular dysfunction 51 Factor Xa 51 lacunar 51 Arrhythmias 51 decompensated heart failure