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(Click for frequent words.) 71 reductase 70 transferase 69 cytochrome 69 lipoxygenase 69 hydrolase 68 mitogen activated protein kinase 68 dehydrogenase 68 68 phosphatidylinositol 68 syntaxin 68 phospholipase 67 catenin 67 cytoplasmic 67 acetyl CoA 67 coactivator 67 mRNA expression 67 phosphorylated 67 decarboxylase 67 oxidase 67 transmembrane protein 67 ERK1 2 67 synthetase 67 histone H3 67 cytosolic 67 biosynthesis 67 glycoprotein 67 membrane protein 67 protein phosphatase 67 ATPase 67 phospho 67 isoforms 67 ubiquitination 67 serine threonine 66 secretase 66 hydrolases 66 N acetyl 66 lysine residues 66 lyase 66 uPAR 66 Rab5 66 transduced 66 immunoreactivity 66 homologue 66 homodimers 66 constitutively 66 phosphatase 66 synthases 66 serine protease 66 subunit 66 downregulated 66 pyrophosphate 66 superfamily 66 RhoA 66 uracil 66 homologs 66 GAPDH 66 tetramer 66 transcriptional regulator 66 constitutively active 66 Phosphorylation 66 VE cadherin 66 cytoplasmic domain 65 phosphorylates 65 alpha subunit 65 defensin 65 oligomerization 65 β 65 phosphorylation 65 transactivation 65 cytochrome P# 65 ß catenin 65 homolog 65 amino acid residue 65 H#K# [002] 65 Synthase 65 cyclooxygenase COX 65 MEK1 65 TGF ß 65 ENaC 65 receptor gene 65 isozymes 65 E3 ligase 65 tropomyosin 65 degrading enzyme 65 BMAL1 65 Catenin 65 CaM 65 centromeric 65 heterodimers 65 converting enzyme 65 cyclins 65 COOH terminal 65 1beta 65 carboxylase 65 leucine zipper 65 NS3 65 cofactor 65 substrate specificity 65 endonuclease 65 cell adhesion molecule 65 GTPase 65 semaphorin 65 4E BP1 65 acetylation 65 metalloproteinase 65 cAMP 64 peroxidase 64 p# mitogen activated 64 acyl CoA 64 androgen receptor AR 64 adhesion molecule 64 superoxide dismutase 64 ribosomal protein 64 phosphatidylinositol 3 64 kinase domain 64 enzymatic activity 64 At#g# 64 polyamine 64 tubulin 64 matrix metalloproteinases MMPs 64 extracellular domain 64 signaling pathway 64 HepG2 cells 64 transcriptional activation 64 heterodimer 64 phosphoprotein 64 plastid 64 proto oncogene 64 dioxygenase 64 genes encoding 64 thyroid hormone receptor 64 fibronectin 64 hydroxylase 64 cytosine 64 regulated kinase ERK 64 dimerization 64 cadherin 64 matrix metalloproteinase 64 isoform 64 Tubulin 64 amino terminal 64 upregulated 64 Overexpression 64 transcriptional repressor 64 aminopeptidase 64 Rab# 64 tyrosine 64 rRNA 64 serine threonine kinase 64 iNOS 64 1alpha 64 presynaptic 64 NR2B 64 glycosyltransferase 64 cyclooxygenase 64 Phenylalanine 64 isoleucine 64 endoplasmic reticulum 64 Fig. 1C 64 null mice 64 neurofilament 64 γ 64 chloroplast 63 triphosphate 63 phosphorylate 63 TIMP 63 ERK signaling 63 MAPK 63 cytochrome c 63 serine 63 biotinylated 63 mediated inhibition 63 Rap1 63 activin 63 CXCL# 63 acylated 63 acetyltransferase 63 AMPA receptor 63 ErbB2 63 protein kinase C 63 FGFR3 63 MAP kinase 63 ESR1 63 HIF 1alpha 63 glucose transporter 63 ribonuclease 63 valine 63 μM 63 ERalpha 63 RANTES 63 desaturase 63 cotransporter 63 constitutively expressed 63 dimeric 63 encodes protein 63 regulated kinase 63 JAK STAT 63 heparan sulfate 63 coiled coil 63 ,#,# [002] 63 tRNA synthetase 63 CagA 63 glutamate receptor 63 methoxy 63 F actin 63 carboxyl terminal 63 beta subunit 63 induced apoptosis 63 EGFP 63 endogenous ligand 63 exocytosis 63 Wnts 63 glyceraldehyde 3 63 LNCaP cells 63 vacuolar 63 budding yeast 63 heme oxygenase 63 Gln 63 methyltransferase 63 Cdc# 63 FOXO3a 63 amino 63 NAD + 63 esterase 63 tyrosine kinase receptor 63 PIP2 63 aspartate 63 protein fragment 63 glutamate receptors 63 selectively inhibits 63 vimentin 63 monomeric 63 acyltransferase 63 mice lacking 63 inducible 63 3' 63 gene encoding 63 protein kinase 63 leukotriene 63 TGF beta1 62 cells transfected 62 monocyte chemotactic protein 62 Aβ 62 GlcNAc 62 forkhead 62 carboxy terminal 62 casein kinase 62 guanine 62 enterocytes 62 oligomeric 62 nucleolar 62 cell adhesion molecules 62 1α 62 adenylate cyclase 62 dependent protein kinase 62 subcellular localization 62 gene encodes 62 receptor tyrosine kinase 62 cyclase 62 antiapoptotic 62 IGF1R 62 p#Kip# 62 JNK1 62 Arabidopsis 62 signaling molecule 62 TRAF6 62 Ca2 + 62 polypeptide 62 intracellular 62 RNA sequences 62 endocytic 62 proapoptotic 62 overexpressing 62 secreted protein 62 NADPH 62 extracellular signal 62 glucocorticoid receptor 62 kDa protein 62 guanosine 62 SIRT2 62 coactivators 62 β1 62 GSTP1 62 glycoproteins 62 FasL 62 oxidative phosphorylation 62 cyclin dependent kinase inhibitor 62 ERK pathway 62 caveolin 1 62 Src 62 ribonucleoprotein 62 tocopherol 62 hypoxia inducible factor 62 Vps# 62 Rac1 62 GLUT4 62 Sp1 62 cytochrome P 62 chemokine receptor 62 Rubisco 62 transcriptional regulation 62 downregulation 62 tyrosine hydroxylase 62 aspartyl 62 hTERT 62 adrenergic receptors 62 FGFR1 62 Notch receptor 62 PcG proteins 62 Fig. 1A 62 deacetylation 62 evolutionarily conserved 62 histidine 62 MT1 MMP 62 IL 1beta 62 muscarinic 62 dephosphorylation 62 prolyl 62 lectin 62 TERT 62 potently inhibits 62 glycogen synthase kinase 62 Kv#.# 62 receptor kinase 62 biochemical pathway 62 actin cytoskeleton 62 eNOS 62 biosynthetic pathway 62 proline 62 isomerase 62 ATP hydrolysis 62 PLA2 62 amino acid residues 62 ERBB2 62 neurokinin 62 autophagic 62 muscarinic receptors 62 PAK1 62 P selectin 62 mRNA 62 prostaglandin E2 PGE2 62 IL 1β 62 diol 62 adrenoceptor 62 ubiquitin ligase 61 transiently transfected 61 receptor subtype 61 glycine 61 prostaglandin E 61 HDACs 61 antisense oligonucleotide 61 cyclic peptide 61 receptor 61 hnRNP 61 enzyme cytochrome 61 disulfide bond 61 wildtype 61 transmembrane domain 61 alkyl 61 monosaccharide 61 scavenger receptor 61 intercellular adhesion molecule 61 GABAergic 61 secretory pathway 61 phosphatases 61 transmembrane domains 61 phosphoinositide 61 TNF receptors 61 thymidine kinase 61 TrkB 61 mediated apoptosis 61 COOH 61 proteolysis 61 CD# CD# 61 nitric oxide synthase 61 IFN gamma 61 transfected 61 upregulation 61 transporter proteins 61 ubiquitylation 61 synaptotagmin 61 mediated phosphorylation 61 transmembrane 61 mannose 61 cathepsin B 61 bile acid 61 5 hydroxytryptamine 61 metabolic enzymes 61 adduct 61 phenotype 61 Aß 61 transcription factor 61 NFAT 61 Nedd4 61 aromatase 61 neuroblastoma cells 61 histone 61 tyrosine kinase 61 proteolytic cleavage 61 beta actin 61 Hypoxia Inducible Factor 61 phorbol 61 acetylcholine receptor 61 dipeptide 61 orthologs 61 downregulates 61 monophosphate 61 BMP2 61 demethylase 61 proteins 61 subunits 61 colocalization 61 metabolizing enzymes 61 TNFalpha 61 KLF4 61 beta amyloid peptide 61 dynamin 61 lysophosphatidic acid 61 IGFBP 61 hexose 61 kinase pathway 61 HER2 HER2 61 ^ sup #m 61 ouabain 61 alpha2 61 transmembrane receptor 61 amide 61 centromeres 61 tumor suppressor protein 61 NKG2D 61 ESCRT 61 paxillin 61 transcription factors 61 secretory 61 extracellular 61 pRb 61 PPARγ 61 PrP 61 isoenzymes 61 pyruvate 61 Supplementary Fig 61 Upregulation 61 calpain 61 fusion protein 61 RecA 61 HEK# cells 61 mRNA encoding 61 Cytochrome 61 LRP6 61 MyoD 61 5' monophosphate 61 catalase 61 copper zinc superoxide 61 ER alpha 61 cystic fibrosis transmembrane conductance 61 TGF β 61 nicotinamide 61 gamma secretase 61 Cre recombinase 61 Cx# [001] 61 ERK1 61 signaling pathways 61 glutathione S transferase 61 acetylcholinesterase 61 glycolipid 61 mitochondrial respiration 61 matrix metalloproteinases 61 Syt II 61 cyclic nucleotide 61 oligomer 61 VEGF receptor 61 Klf4 61 proteinase 61 acetylated 61 adenosine diphosphate ADP 61 Î ² 61 CCL2 61 glycolipids 61 cytidine 61 cytokine receptor 61 stilbene 61 isoprenoid 61 quinone 61 fig. S2 61 Fas ligand 61 TAp# 61 tyrosine phosphorylation 61 ligand receptor 61 cyclin E 61 glucan 61 N methyl 61 cysteine 61 enzyme 61 histone acetyltransferase 61 EP4 61 cyclin 61 receptor blocker 61 deoxy 61 kinase 61 proteolytic 61 FGF2 61 glycosylated 60 disulfide 60 E#F# 60 enzymatic 60 TNFR 60 dsRNA 60 CYP#B# 60 lysosomal 60 phosphate S1P 60 estrogen receptor beta 60 K + ATPase 60 anaphase promoting complex 60 RNA polymerases 60 polycystin 60 inverse agonist 60 cysteine protease 60 Microtubule 60 gene encodes protein 60 PTPN# 60 receptor gamma 60 pyrimidines 60 microsomal 60 ribonucleotide 60 ubiquitinated 60 phagocytosis 60 IFN alpha 60 5 lipoxygenase 60 annexin V 60 retinoic acid receptor 60 EF Tu 60 phosphorylase 60 overexpress 60 succinate 60 Supplemental Figure 60 vWF 60 alternatively spliced 60 focal adhesion kinase FAK 60 E1A 60 TIMP 1 60 adrenergic receptor 60 TNF α 60 ras gene 60 erythrocytes 60 PcG 60 induces apoptosis 60 miR# 60 Saccharomyces cerevisiae 60 hydrogenase 60 protein tyrosine kinase 60 polyadenylation 60 radiolabeled 60 ornithine 60 kinase gene 60 SNAREs 60 BCL2 60 MMP2 60 bradykinin 60 condensin 60 histone deacetylases 60 postsynaptic 60 tetramers 60 estrogen receptor alpha 60 GTPases 60 caveolin 60 diphosphate 60 hydroxyphenyl 60 serpin 60 Peyer patches 60 microglial 60 Mcl 1 60 bacterial enzyme 60 c myc 60 OCT4 60 thrombospondin 60 cytokines IL 60 RNA splicing 60 glycogen synthase 60 Mice deficient 60 Tie2 60 glioma cells 60 SMase 60 demethylation 60 mRNA transcripts 60 cofilin 60 polypeptides 60 #ß 60 carboxy 60 PAX5 60 SH2 domain 60 Smad4 60 Activating mutations 60 intramolecular 60 oncoprotein 60 apoE4 60 endocytosis 60 LDL receptor 60 EBNA1 60 glucosides 60 mononuclear 60 peroxisome proliferator activated 60 T#M 60 ^ sup ^ 60 H#K# [001] 60 β catenin 60 avidin 60 receptor alpha 60 6S RNA 60 5HT 60 Foxp3 60 CFTR cystic fibrosis transmembrane 60 TGF b 60 pDC 60 p# MAPK 60 ALDH 60 eukaryotic 60 receptor antagonists 60 molecule 60 palytoxin 60 pyrimidine 60 BACE1 60 constitutively activated 60 coenzyme 60 diacylglycerol 60 cyclin D1 60 isoenzyme 60 VEGFR1 60 osteocalcin 60 S#A# [002] 60 catalytic subunit 60 vascular endothelial cells 60 homodimer 60 midgut 60 constitutive activation 60 clathrin 60 SGK1 60 PDGFR 60 receptor molecule 60 chemokine 60 Caspase 60 proximal tubule 60 hippocampal neurons 60 upregulating 60 melanocyte 60 mGluRs 60 potent inhibitors 60 receptor mediated 60 peptidase 60 TGF β1 60 selective inhibitor 60 glycolysis 60 dismutase 60 dystroglycan 60 glycosylation 60 galactosidase 60 Rho GTPases 60 BMP signaling 60 carboxylic acid 60 peroxisomal 60 Rho GTPase 60 E selectin 60 CYP#A# [002] 60 Extracellular 60 metalloproteinases 60 threonine 60 CXCR2 60 transmembrane proteins 60 LPS induced 60 abscisic acid 60 D aspartic acid 60 5 HT1A 60 ERK 60 N acetyltransferase 60 N acetylglucosamine 60 TRPV4 60 glucans 60 Gly 60 caspases 60 metabolic pathway 60 cytoplasmic tail 60 M1 muscarinic 60 oncogenic 60 PAR1 59 Macrophage 59 prostate epithelial cells 59 ligands 59 elastase 59 uncoupling protein 59 ciliated 59 Amino acid 59 mimetic peptide 59 keratinocytes 59 Caenorhabditis elegans 59 glucoside 59 EphB4 59 murine 59 CDK4 59 tyrosine residues 59 posttranslational modification 59 glutamine synthetase 59 Rho kinase 59 myocyte enhancer factor 59 GLI1 59 transcriptionally active 59 palmitate 59 epoxide 59 Smad 59 E3 ubiquitin ligase 59 inhibitory activity 59 intracellular pH 59 acyl 59 GluR1 59 plasma membrane 59 integrins 59 PON1 59 functional polymorphism 59 Abl 59 sphingosine 1 59 Peroxisome proliferator activated 59 Chinese Hamster Ovary 59 covalently attached 59 metalloprotease 59 AChE 59 transferrin receptor 59 Runx2 59 cytokine signaling 59 inhibitory effects 59 Interferon gamma 59 interleukin IL 59 PI3 kinase 59 C3b 59 operon 59 Protein Kinase C 59 PGC 1α 59 IFN γ 59 opioid receptor 59 ovalbumin 59 mM NaCl 59 telomerase reverse transcriptase 59 TORC2 59 Topoisomerase 59 aggrecan 59 ChR2 59 receptors PPARs 59 IRE1 59 receptor subunit 59 Protein kinase 59 synaptogenesis 59 SUMOylation 59 methyl D aspartate 59 receptor signaling 59 palladin 59 cytochromes 59 oligosaccharide 59 carboxylate 59 phytochrome 59 ErbB 59 Smad3 59 synaptic vesicle 59 SOD1 59 dimethyl 59 RNA binding 59 Methionine 59 protease 59 hydroxylation 59 protein encoded 59 dimers 59 monocyte 59 eotaxin 59 claudin 59 mTOR signaling 59 MAPK pathway 59 mammalian fatty acid 59 apolipoprotein 59 proteases 59 RAR beta 59 retinoid X 59 somatostatin 59 histone H4 59 AMACR 59 protein 59 topoisomerase II 59 AT1R 59 neuropeptide 59 transduction 59 nucleolin 59 Tumor necrosis factor 59 HDAC2 59 BCR ABL 59 hydrolyzing 59 arginase 59 Kupffer cells 59 MEFs 59 porphyrin 59 enzyme secreted 59 ligand binding 59 dinucleotide 59 γ secretase 59 IL 1ß 59 apoE 59 P2X 59 regulates gene expression 59 hyperactivation 59 TGF alpha 59 E cadherin 59 β2 59 chromatin structure 59 biogenesis 59 STAT3 59 guanine nucleotide exchange 59 neurite outgrowth 59 Transgenic Mice 59 COL#A# 59 isoprostane 59 protein tyrosine phosphatase 59 SGLT 59 caspase 59 fig. S1 59 uM 59 chaperone protein 59 beta tubulin 59 histone methyltransferase 59 Pol IV 59 Th2 59 cytochrome c oxidase 59 cathepsins 59 peptide CGRP 59 5alpha reductase 59 gluconeogenesis 59 signaling cascade 59 C. albicans 59 epigenetic silencing 59 neuronal signaling 59 receptor activation 59 Aâ 59 N cadherin 59 FOXO 59 thrombin receptor 59 chemoattractant 59 Notch signaling 59 morphogen 59 methyltransferases 59 anterior pituitary 59 A. thaliana 59 Huntingtin 59 carcinoembryonic antigen 59 proteoglycan 59 ultrastructure 59 fission yeast 59 Htt 59 factor HGF 59 cytosol 59 ß1 59 cerevisiae 59 cyclin dependent kinase 59 homologues 59 cannabinoid receptor 59 adipogenic 59 bleomycin 59 mol L 59 VSV G 59 5alpha 59 KaiC 59 ganglioside 59 BMP receptor 59 lipase 59 Fig. 2C 59 stably transfected 59 deacetylases 59 aryl hydrocarbon receptor 59 cis 59 mutant proteins 59 SOCS3 59 auxin 59 glutamyl 59 perivascular 59 thioredoxin 59 coexpression 59 thymidine 59 myo inositol 59 Notch1 59 Fig. 1E 59 huntingtin 59 + ATPase 59 kD 59 inhibitory 59 TGF ß1 59 BH3 59 LRAT 59 c Src 59 mucins 59 outer membrane proteins 59 lamin 59 ABCA1 59 FKBP# 59 noncoding RNA 59 ß 59 Bcl XL 59 Arp2 3 59 IL# [001] 59 HDAC6 59 integrin alpha 59 aberrantly activated 59 NKCC1 59 survivin 59 ligase 59 cyclin dependent kinases 59 DLX5 58 subtilisin 58 basolateral 58 PC# cells 58 HOTAIR 58 HIP1 58 drug metabolizing enzyme 58 DNMT1 58 factor kappa B 58 PML RARA 58 mitochondrial biogenesis 58 integrin 58 Golgi 58 hydroxypropyl 58 de novo synthesis 58 Skp2 58 S. cerevisiae 58 Wnt signaling 58 oxidative metabolism 58 cysteine residues 58 pro apoptotic 58 CCL# 58 cholecystokinin CCK 58 retinoic acid 58 potent inhibitor 58 AhR 58 hydroxy 58 antioxidant enzyme 58 endothelial nitric oxide synthase 58 moieties 58 inhibitory effect 58 c Myb 58 caveolae 58 proline rich 58 pyridyl 58 poly ADP ribose polymerase 58 indole 58 SLC#A# [002] 58 endosomes 58 cyclooxygenase 2 58 ALDH2 58 heterochromatic 58 enkephalin 58 cytokeratin 58 asparagine 58 miR #a [001] 58 phospholipase A2 58 bases adenine 58 NFkappaB 58 mutant protein 58 nitric oxide synthase NOS 58 phenylene 58 PKC isoforms 58 transient receptor 58 unmethylated 58 transcriptionally 58 Secretase 58 protein secreted 58 phospholipase D 58 neuronal differentiation 58 recombinase 58 amine oxidase 58 gamma aminobutyric acid 58 c Fos 58 NMDA N 58 ligand TRAIL 58 active metabolite 58 adenylyl cyclase 58 interleukins 58 mitotic progression 58 cyclic AMP 58 dimer 58 HSP# 58 signal transduction 58 1ß 58 conformational changes 58 transcriptional regulators 58 flavin 58 receptor protein 58 actin binding 58 Cyclin E 58 Cytochrome P# 58 aquaporin 58 keratinocyte 58 drug metabolizing enzymes 58 Histone 58 Protein Kinase 58 CD1d 58 mPGES 1 58 E cadherin expression 58 microglial activation 58 enzymatically