Related by context. All words. (Click for frequent words.) 79 reactive oxygen species 75 superoxide 71 oxidative stress inflammation 71 peroxynitrite 70 NADPH oxidase 69 lipid peroxides 69 reactive oxygen 69 prostaglandin E2 68 Oxidative stress 67 Reactive oxygen species 67 antioxidant enzyme 67 IL 1beta 67 selective inhibition 67 intracellularly 67 superoxide radicals 67 hydroxyl radicals 67 anti apoptotic 67 superoxide anion 66 catalase 66 TGF ß1 66 lipid peroxidation 66 excitotoxic 66 reactive oxygen molecules 66 hydroxyl radical 66 singlet oxygen 66 prostaglandin E2 PGE2 66 superoxides 65 ERK1 2 65 polyamines 65 NAD + 65 thyrotropin 65 Rap1 65 proteolytic enzymes 65 NF κB 65 elastase 65 glycolipids 65 inflammatory cytokines 65 proteolysis 65 TSLP 65 cytochrome c 65 protein kinase C 65 Aß 65 TNF α 65 oncoprotein 65 proinflammatory cytokines 65 IL #p# 65 apoptotic pathway 65 heme oxygenase 65 mitogen activated protein kinase 64 nitric oxide synthase 64 oxidative stress 64 prostaglandin synthesis 64 oxidants 64 Rab5 64 IL 1β 64 c MYC 64 inflammatory cytokine 64 endoplasmic reticulum stress 64 Wnt signaling 64 TGF beta1 64 hematopoietic cells 64 mitogen 64 MAP kinase 64 mitochondrial biogenesis 64 caveolin 1 64 eicosanoid 64 adipokines 64 Fas ligand 64 p#NTR 64 p# activation 64 eicosanoids 64 microglial 64 peroxidation 64 TGF b 64 4E BP1 64 myeloid derived 64 deacetylation 64 amyloid beta peptides 64 genotoxic stress 64 phagocytes 64 antioxidant enzymes 64 cyclic AMP cAMP 64 cathepsins 64 lysosomal 64 ABCA1 64 lipogenesis 64 inducible nitric oxide synthase 64 Hsp# [001] 64 heme oxygenase 1 63 eNOS 63 glucocorticoid receptor 63 TGF alpha 63 microglial cells 63 LDL receptor 63 adipocyte 63 amyloid peptide 63 frataxin 63 p# MAPK 63 GPx 63 excitatory neurotransmitter glutamate 63 renal fibrosis 63 PHD2 63 anti inflammatory cytokine 63 UCP2 63 glutamate receptors 63 reactive molecules 63 TNFa 63 beta amyloid peptide 63 phosphorylates 63 cytokine signaling 63 superoxide dismutase SOD 63 MDSCs 63 LRP6 63 procaspase 3 63 cyclic AMP 63 endothelial nitric oxide 63 Smad3 63 JAK2 enzyme 63 Th2 cells 63 SGK1 63 chitinase 63 NPD1 63 pro inflammatory cytokines 63 ferulic acid 63 IL 1ß 63 TGF β 63 adipogenesis 63 cytokines 63 Abeta# 63 catecholamine 63 thioredoxin 63 histone deacetylases 63 ceramide 63 MMP9 63 Leukotrienes 63 ERK signaling 63 steroid hormones 63 oxidative phosphorylation 63 tumor suppressor protein 63 transcriptional activation 63 activin 62 cyclic adenosine monophosphate cAMP 62 paxillin 62 induced neuronal 62 HSF1 62 phosphate S1P 62 EphA2 62 EphB2 62 Skp2 62 TNFalpha 62 iNOS 62 allergic inflammation 62 MAPKs 62 metabolic enzymes 62 β cells 62 spermidine 62 triggers apoptosis 62 Nitric oxide NO 62 overactivation 62 toxic amyloid beta 62 matrix metalloproteinases 62 beta catenin protein 62 microglial activation 62 osteoblast 62 suppressor cells 62 bile acids 62 sphingolipid 62 Drp1 62 endothelial nitric oxide synthase 62 mucins 62 nitric oxide NO 62 proinflammatory cytokine 62 proto oncogene 62 redox active 62 CYP#B# 62 HbF 62 catenin 62 Macrophage 62 oxidative enzymes 62 naturally occurring enzyme 62 TGFβ 62 malonyl CoA 62 constitutively 62 glutathione GSH 62 cardiac fibroblasts 62 NKG2D 62 enzymatic pathways 62 arachidonic acid 62 antiapoptotic 62 MEK ERK 62 neurite outgrowth 62 proteases 62 intestinal epithelium 62 hydroperoxide 62 IFN gamma 62 cyclooxygenase 62 SIRT2 62 CLL cells 62 cellular prion protein 62 Clusterin 62 glycation 62 GLI1 62 neutrophil elastase 62 catabolism 62 PKC isoforms 62 lipoxygenase 62 proinflammatory 62 myeloid cells 62 cyclic adenosine monophosphate 62 metalloproteases 62 quinone 62 amyloid deposition 62 thyroxine T4 61 peroxisome 61 aldehyde dehydrogenase 61 osteopontin 61 hydrolases 61 PGE2 61 superoxide dismutase 61 adrenal cortex 61 fatty acid oxidation 61 Th1 type 61 acetyl CoA 61 endogenous cannabinoids 61 leukotrienes 61 pro inflammatory cytokine 61 Cathepsin B 61 cyclic GMP 61 FGFs 61 pathophysiological effects 61 phagocytosis 61 caspase activation 61 ACh 61 signaling cascades 61 daidzein 61 amyloid ß 61 reactive nitrogen 61 Aldosterone 61 basophils 61 osteocalcin 61 Hypoxia Inducible Factor 61 cytoprotective 61 Hedgehog signaling 61 TGF ß 61 carnosine 61 hyperactivation 61 dopaminergic neurons 61 AhR 61 Oncogenic 61 Aβ 61 autophagic 61 neuropeptide Y NPY 61 Nrf2 61 tyrosine phosphorylation 61 pDCs 61 mesenchymal cells 61 synuclein 61 acyl CoA 61 NFκB 61 myofibroblast 61 synaptogenesis 61 interleukins 61 inhibitory effect 61 SIRT3 61 VEGF receptor 61 lipopolysaccharide 61 oxidative 61 osteogenic differentiation 61 Skeletal muscle 61 radical scavenging 61 CCL# 61 aberrantly activated 61 oxidase 61 neurotrophic 61 lipofuscin 61 RANKL 61 estrone 61 Leydig cells 61 endogenous ligands 61 SCD1 61 genomic instability 61 Aβ# 61 intestinal epithelial cells 61 bile acid 61 cathepsin B 61 adipose cells 61 lymphocyte proliferation 61 calcineurin 61 intracellular accumulation 61 secreted protein 61 Reactive Oxygen Species 61 PI3K pathway 61 urease 61 Runx2 61 β catenin 61 cytolytic 61 androgen receptor AR 61 Th2 61 hypoxia inducible factor 61 acinar 61 GABAA receptors 61 Ca2 + 61 protein CETP 61 cAMP 61 podocytes 61 super oxide dismutase 61 plasmacytoid dendritic cells 61 oxidant stress 61 fibrin deposition 61 extracellular signal 61 inflammatory mediators 61 excitotoxicity 61 nitrotyrosine 61 Treg cells 61 angiotensinogen 61 mitochondrial respiration 61 aminobutyric acid 61 glial cell 61 adenosine diphosphate ADP 61 5 lipoxygenase 61 TXNIP 61 Vpr 61 FGF# 61 PDGFR 61 potent inducer 61 metallothionein 61 metalloprotease 61 HDAC6 61 amyloid β 61 nitric oxide synthase NOS 61 ubiquitylation 61 dimerization 60 glycosaminoglycans 60 immunomodulatory effects 60 prostaglandin E 60 caspases 60 mesenchymal cell 60 ubiquinol 60 MEK1 60 radical scavenger 60 PTPN# 60 keratinocyte 60 vascular endothelial cells 60 RANTES 60 NKT cell 60 CXCL# 60 oxidases 60 intracellular calcium 60 serine protease 60 glucocerebroside primarily 60 Alu RNA 60 galanin 60 plasminogen 60 ENaC 60 adipokine 60 Th2 cytokines 60 anti inflammatory cytokines 60 T lymphocyte 60 synovial cells 60 NKT cells 60 dopaminergic cells 60 oxidized LDL 60 MAP kinases 60 phosphatidylinositol 3 60 oncogenic 60 IFNg 60 NFkB 60 histone acetylation 60 neurotrophins 60 GluR1 60 STAT3 60 c MET 60 spermatogenesis 60 LRP5 60 pro apoptotic 60 Oxidative stress occurs 60 neuronal dysfunction 60 diffusible 60 Mcl 1 60 cardiac myocytes 60 tubulin polymerization 60 telomere dysfunction 60 thromboxane A2 60 TMEM#B 60 ARF1 60 Glucocorticoids 60 peroxisome proliferator activated 60 toxic beta amyloid 60 estrogen receptor alpha 60 interferon γ 60 IGF1R 60 ERK phosphorylation 60 cellular metabolism 60 RIP1 60 nNOS 60 progranulin 60 NF KappaB 60 anabolism 60 TGF beta pathway 60 IKK2 60 proton pump 60 antiproliferative effects 60 stromal cells 60 effector T 60 endothelial progenitor cells 60 Src kinase 60 Cyclin D1 60 adrenoceptor 60 excess TNF alpha 60 N methyl 60 CCL5 60 von Willebrand factor 60 intracellular proteins 60 fatty molecules 60 E3 ligase 60 serine threonine 60 cytotoxic T lymphocytes 60 cyclin E 60 induced apoptosis 60 p#Kip# 60 PPARγ 60 oligomeric 60 tau phosphorylation 60 innate immune 60 transgene expression 60 mitogen activated protein kinases 60 proteolytic enzyme 60 alpha synuclein 60 FGFR3 60 RAS RAF MEK 60 interferon gamma 60 extracellular calcium 60 sFlt 1 60 fatty acid synthase 60 melanin pigments 60 uPA 60 tumorigenic 60 neurofibromin 60 MDR1 60 neurotransmitter glutamate 60 NF kappaB activation 60 hypothalamic pituitary 60 mutant huntingtin protein 60 LNCaP cells 60 PIP3 60 E#F# 60 cofactor 60 senescent cells 60 collagen synthesis 60 KLF2 60 retinoid X 60 NFkappaB 60 LTB4 60 oxidative DNA 60 Prolactin 60 morphogen 60 enzyme aromatase 60 mitogenic 60 protein tyrosine phosphatase 60 adipocyte differentiation 60 melanocyte 60 superantigens 60 cell adhesion molecule 60 neuropeptide Y 60 brain derived neurotrophic 60 hepatic glucose production 60 adhesion molecule 60 PEDF 60 adenylate cyclase 60 NQO1 60 apoE 60 Th# cells 60 naturally occurring amino acid 59 granzyme B 59 EGF receptor 59 CDDO Im 59 fibrocytes 59 ouabain 59 ERK activation 59 effector functions 59 prostate epithelial cells 59 plasma fibrinogen 59 glutathione 59 oligomers 59 c Src 59 ectopic expression 59 palmitoleate 59 dysregulation 59 GRK2 59 aryl hydrocarbon receptor 59 mevalonate 59 B7 H1 59 oxidative damage 59 sortilin 59 amyloid peptides 59 HDAC2 59 regulated kinase ERK 59 CD1d 59 retinoic acid 59 malate 59 mammary cells 59 incretins 59 anthrax toxins 59 mutated protein 59 nitrite nitrate 59 gluconeogenesis 59 NF KB 59 matrix metalloproteinases MMPs 59 topoisomerase II 59 induces apoptosis 59 goblet cells 59 systemic inflammation 59 collagens 59 upregulation 59 tumor suppressor proteins 59 dehydrogenases 59 aldosterone 59 HIF 1alpha 59 GAPDH 59 proteosome 59 paracrine 59 selenoproteins 59 de novo lipogenesis 59 factor PlGF 59 monocyte chemotactic protein 59 COX enzymes 59 IFN ß 59 abzymes 59 reductase 59 myeloperoxidase 59 EZH2 59 enterolactone 59 HIF 1a 59 abscisic acid 59 pleiotropic 59 podocyte 59 Cyclin E 59 normal prion protein 59 Propionibacterium acnes 59 RANK Ligand 59 BLyS 59 induce apoptosis 59 alveolar macrophages 59 myeloma cells 59 Superoxide 59 copper zinc superoxide 59 MT1 MMP 59 Monocyte 59 asparagine 59 pRb 59 oxidant 59 isothiocyanates 59 LPS induced 59 mutant proteins 59 TLR4 59 p# MAP kinase 59 upregulates 59 cholecystokinin CCK 59 NFAT 59 PrP 59 cAMP signaling 59 PAK1 59 neuroblastoma cells 59 potent inhibition 59 pro apoptotic proteins 59 matrix metalloproteinase 59 caveolin 59 amyloid beta peptide 59 cyclooxygenase COX 59 TGF β1 59 somatostatin 59 microvascular endothelial cells 59 APOBEC3G 59 CTGF 59 Oxidative 59 cyclin B1 59 dephosphorylation 59 constitutively active 59 mitochondrial mutations 59 proNGF 59 prostaglandins 59 mitochondria 59 Akt activation 59 prostaglandin D2 59 Factor VEGF 59 pro angiogenic 59 mediated inhibition 59 thymocytes 59 commensal bacteria 59 Epstein Barr Virus EBV 59 presynaptic 59 triphosphate 59 Monocytes 59 oligodendrocyte progenitor cells 59 Sulforaphane 59 vascular permeability 59 neurofibrillary tangles 59 noradrenaline 59 Foxp3 59 activated microglia 59 endosomal 59 monocyte 59 HepG2 cells 59 beta adrenergic receptors 59 HIF 1α 59 59 lymphocyte activation 59 interleukin IL -6 59 PPARgamma 59 miR #a [002] 59 neurotransmitter GABA 59 upregulating 59 androgen hormones 59 Aâ 59 eosinophils 59 GAGs 59 bacterial enzymes 59 Nedd4 59 MnSOD 59 neurotransmission 59 homodimers 59 naturally occurring molecule 59 actin polymerization 59 ovarian hormones 59 cyclic guanosine monophosphate 59 Notch signaling 59 serine proteases 59 anti apoptotic proteins 59 male hormone androgen 59 Aromatase 59 neurotransmitter acetylcholine 59 cytokine IL 59 estrogen metabolism 59 bacterial enzyme 59 TTR gene 59 amyloid protein 59 natriuretic peptides 59 adduct 59 neuromuscular junction 59 MDM2 59 cyclooxygenase 2 59 hormone aldosterone 59 HIF1 alpha 59 Hh pathway 59 FOXO1 59 ptau 59 enzyme cofactor 59 cytokine 59 cell adhesion molecules 59 RBP4 59 putrescine 59 adrenocortical 59 alpha TNFa 59 LPA1 receptor 59 porphyrins 59 IGFBP 3 59 Sirtuins 59 enzymatic activity 59 hyperactivated 59 telomerase activity 59 bacterial toxins 59 fetal hemoglobin 59 mutant huntingtin 59 synthetase 59 enterocytes 59 endocrine glands 59 NF kappaB 59 intracellular 59 BACE1 59 calcium homeostasis 59 c fos 58 secretase 58 proteoglycans 58 mutagens 58 antimicrobial peptides 58 intracellular pathways 58 microtubule dynamics 58 neuronal plasticity 58 TGF Beta 58 TRAIL induced apoptosis 58 Smoothened 58 ß amyloid 58 inhibiting enzymes 58 SGLT2 58 haematopoietic 58 factor HGF 58 lymphoid cells 58 estrogen receptor beta 58 xanthine 58 proteoglycan 58 IL 1Ra 58 glucosides 58 TGF beta signaling 58 proapoptotic 58 cellular respiration 58 Angiotensin II 58 cytokine interleukin 58 glycolytic 58 pyrimidines 58 hyperinsulinemia 58 lyase 58 TAp# 58 apoptosis programmed cell 58 autoantigens 58 vimentin 58 killer NK 58 Vps# 58 aromatase 58 NK1R 58 transgenic rats 58 CD#L 58 redox reactions 58 amyloid beta plaques 58 BCL#A 58 lymphotoxin 58 receptor gamma 58 tumorigenesis 58 gamma tocotrienol 58 TIR1 58 hormone cortisol 58 pharmacological inhibition 58 Adiponectin 58 oncogenic transformation 58 autocrine 58 effector molecules 58 hypochlorous acid 58 p# protein 58 TET2 58 neutrophil infiltration 58 polyamine 58 LDL oxidation 58 RANK ligand 58 effector memory 58 C EBP alpha 58 casein kinase 58 chromosomal aberrations 58 SETDB1 58 interleukin 1beta 58 brown adipose tissue 58 humoral immunity 58 Osteoclasts 58 lipid synthesis 58 antimicrobial peptide 58 neural cells 58 myofibroblasts 58 Smurf1 58 arginase 58 CD8 T cells 58 mediated apoptosis 58 protein alpha synuclein 58 M1 macrophages 58 isoenzyme 58 fibrogenesis 58 S6K 58 apoptosis induced 58 glutathione peroxidase 58 amyloid proteins 58 glioblastoma cells 58 polymorphonuclear leukocytes 58 dendritic cells DCs 58 receptor subtype 58 HSP# 58 Phosphorylation 58 phagocytic cells 58 JNK activation 58 calpain 58 p# alpha [001] 58 beta1 integrin 58 acetylcholine receptor 58 lung epithelial cells 58 P glycoprotein 58 TSP1 58 annexin V 58 UCP1 58 PrPC 58 vasodilatory 58 acetylcholinesterase AChE 58 innate immune responses 58 detoxification enzymes 58 MAPK pathway 58 CD4 + CD# 58 NADPH 58 intracellular protein 58 filamentous fungus 58 NO synthase 58 androgen receptors 58 Notch receptor 58 cyclin dependent kinase 58 erythrocytes 58 RhoA 58 astrocytic 58 IL6 58 GABAergic interneurons 58 pancreatic islet 58 focal adhesion kinase FAK 58 Wnts 58 mPGES 1 58 insulin secreting cells 58 dihydrotestosterone DHT 58 retinoic acid receptor 58 #BP# 58 T lymphocytes 58 CoQ 58 leukemic cell 58 dismutase 58 lymphangiogenesis 58 ganglioside 58 ketone bodies 58 peroxisomes 58 lysosome 58 adipogenic 58 apoptotic 58 alveolar epithelial cells 58 glucocorticoids 58 hematopoietic 58 c myc 58 mediating pathological inflammation 58 airway hyper responsiveness 58 Overexpression 58 Protein Kinase C 58 pancreatic islet beta 58 PC# cells 58 myo inositol 58 glioma cells 58 species ROS 58 TGFbeta 58 oxidizing agent 58 NADH 58 OGG1 58 beta amyloid peptides 58 BCL2 58 Th1 cells 58 catecholamines 58 cell signaling pathway 58 MMP2 58 Hedgehog pathway 58 purines 58 Androgen 58 Id1 58 xenobiotic 58 extracellular matrix proteins 58 arsenite 58 palytoxin 58 tryptase 58 primary cilia 58 prostanoid 58 nitric oxide 58 Cdc# 58 neurotransmitters dopamine 58 thiocyanate 58 angiotensin II 58 Endotoxin 58 β amyloid 58 adrenal hormones 58 HBx 58 HPA axis 58 thymic 58 lysyl oxidase 58 macrophage 58 neuronal cell 58 macrophage cells 58 PPARg 58 oxalate 58 mitochondrial proteins 58 TORC2 58 granulocytes 58 pyruvate 58 antioxidant glutathione 58 ligand TRAIL 58 hedgehog pathway 58 downregulation 58 oligomerization 58 #beta HSD1 58 oxidized lipids 58 Wnt signaling pathway 58 cultured hippocampal neurons 58 ADAM# 58 metalloproteinase 58 leukocyte adhesion 58 cyclin D1 58 K + ATPase 58 autoreactive 58 mtDNA mutations 58 hypothalamic pituitary adrenal axis 58 triacylglycerol 58 circadian clock genes 58 SIRT6 58 Neu5Gc 58 digesting enzymes 58 diacylglycerol 58 DNA adducts 58 MAPK 58 renin angiotensin system 58 glycolysis 58 mutant protein 58 BRAF gene 58 Smad7 58 adrenomedullin 58 inhibitory effects 58 #S proteasome 58 intracellular bacteria 58 acetylation 58 VEGF expression 58 cytokine receptor 58 nucleolar 58 natriuresis 58 nAChRs 58 FGF2 58 cofilin 58 CTLs 58 neuronal differentiation 58 antioxidant nutrients 58 cholesterol efflux 58 LKB1 58 BMP2 58 TNF receptors 58 SUMOylation 58 related apoptosis inducing 58 chemically reactive 58 TGF beta 58 coenzyme 58 Klotho 58 Arginine 58 tumor metastasis 58 Abeta 58 subcellular compartments 58 intracellular pH 58 osteoprotegerin 57 lipoprotein lipase 57 VE cadherin 57 megakaryocytes 57 retinal ischemia 57 secretory pathway 57 peripheral tissues 57 autophagy 57 amyloid beta protein 57 mitochondrial function 57 endocytosis 57 DHEAS 57 autoantibodies antibodies 57 VEGF protein 57 dehydrogenase 57 genes encode proteins 57 potent carcinogen 57 PDE1 57 triiodothyronine 57 macrophage infiltration 57 Endothelin 57 myrosinase 57 Extracellular 57 Interferon gamma 57 immunoreactivity 57 Bcl xL 57 purine 57 molecular signaling pathway 57 Oxidative damage 57 ERK pathway 57 neurotrophic factors 57 cellular senescence 57 gonadotropins 57 hepatocyte growth 57 N Myc 57 5 HT1A 57 signaling pathway 57 Cytotoxic T 57 ellagic acid 57 lymphoid organs 57 VLDL cholesterol 57 endoxifen 57 β cell 57 malondialdehyde 57 ubiquitination 57 CYP #A# 57 invadopodia formation 57 Shiga toxin 57 HOTAIR 57 luciferin 57 luteolin 57 phospho 57 vWF 57 nestin 57 cathelicidin 57 chondrocytes 57 factor GDNF 57 acrolein 57 ionizing irradiation 57 cyclophilin D 57 Wnt beta catenin 57 pDC 57 cholecystokinin 57 retinal neurons 57 SIRT1 57 antitumor 57 acetylcholinesterase 57 carcinogenic compounds 57 melanocyte stimulating hormone 57 cell motility 57 FUS1 57 glucocorticoid receptors