Related by context. All words. (Click for frequent words.) 83 anti apoptotic 76 anti proliferative 74 antiapoptotic 74 cytoprotective 73 c MYC 73 induces apoptosis 72 inhibitory effects 72 VEGF receptor 72 TNFalpha 72 c MET 72 anti inflammatory cytokines 72 eNOS 71 NKG2D 71 PDGFR 71 antitumor 71 selective inhibition 71 ERK1 2 71 E#F# 71 mitogen activated protein kinase 70 antiangiogenic 70 FasL 70 potent inhibition 70 potent antiproliferative 70 TGF beta1 70 cyclin E 70 immunoregulatory 70 SIRT2 70 induce apoptosis 70 VEGFR2 70 carcinoembryonic antigen 70 deacetylation 70 N methyl 70 factor HGF 70 immunomodulating 70 phosphatidylinositol 3 70 phosphate S1P 70 IFN γ 70 ENMD # 70 potent inhibitor 70 TNF α 70 reversible inhibitor 70 anti angiogenic 70 selective antagonist 70 HIF 1alpha 70 pro angiogenic 69 IL 1beta 69 ligand TRAIL 69 IL #p# 69 lymphotoxin 69 #HT#A 69 EGF receptor 69 TNFα 69 selectively inhibits 69 cyclooxygenase COX 69 receptor activation 69 mitogenic 69 neurotrophic 69 vWF 69 CCR2 69 peroxisome proliferator activated 69 TGF β 69 catenin 69 cyclooxygenase 2 69 proapoptotic 69 ERK pathway 69 ERa 69 tau phosphorylation 69 activin 69 neurite outgrowth 69 p#Kip# 69 partial agonist 69 dimerization 69 selective inhibitor 69 BCL2 69 potent anticancer 69 IL 1β 69 tubulin polymerization 69 TGF ß 68 Aurora kinase 68 glucocorticoid receptor 68 HDAC 68 pro inflammatory cytokine 68 sphingosine 1 68 EphA2 68 immunostimulatory 68 mitogen 68 p# MAP kinase 68 insulin sensitizing 68 TRAIL induced apoptosis 68 muscarinic 68 DNMT1 68 phosphatases 68 androgen receptor AR 68 related apoptosis inducing 68 clusterin 68 serine threonine 68 RhoA 68 aberrantly activated 68 xenograft models 68 antiproliferative effects 68 beta subunit 68 FGFR4 68 dephosphorylation 68 Eg5 68 inducible nitric oxide synthase 68 PGE2 68 IL 1ß 68 mediated inhibition 68 ErbB2 68 TGF β1 68 hepatocyte growth 68 potently inhibited 68 EGFr 68 upregulation 68 MMP7 68 antiproliferative 68 iNOS 68 HepG2 cells 68 tumorigenic 68 GLI1 68 survivin 68 highly selective inhibitor 68 TRAIL R2 68 mineralocorticoid 68 apoptosis inducing 68 constitutively active 68 anti leukemic 68 HIF 1α 68 TrkA 68 AT1R 68 effector function 68 PI3K Akt 68 antiproliferative activity 67 prostaglandin E2 PGE2 67 hypoxia inducible factor 67 adrenoceptor 67 protein kinase C 67 ACh 67 renal fibrosis 67 c Fos 67 5 HT2A receptor 67 ectopic expression 67 LTB4 67 ERalpha 67 selectively inhibited 67 adipogenic 67 nitric oxide synthase 67 glucagon receptor 67 PPARγ 67 immune stimulatory 67 CXCL# 67 pathophysiological effects 67 Notch1 67 osteoblast 67 Vascular endothelial growth 67 IGF1R 67 HSP# inhibitor 67 tyrosine kinase receptor 67 uPAR 67 Clusterin 67 superoxide dismutase 67 receptor tyrosine kinase 67 regulated kinase 67 HDAC2 67 MAPK pathway 67 potently inhibits 67 potent antitumor 67 PTP 1B 67 XL# inhibits 67 Akt activation 67 targeting CD# 67 PPARgamma 67 STAT1 67 Runx2 67 mTOR mammalian target 67 NFκB 67 Bcl xL 67 immunoreactivity 67 IL6 67 caveolin 1 67 inflammatory cytokines 67 cyclooxygenase 67 CatB 67 MAP kinase 67 PPARg 67 microglial activation 67 Aβ 67 MDM2 67 IL #E 67 HIF 1a 67 homodimers 67 γ secretase 67 endothelial nitric oxide synthase 67 IGFBP 3 67 paxillin 67 Upregulation 67 cytokine signaling 67 antitumor effects 67 transactivation 67 ABCA1 67 phosphoinositide 3 67 Akt signaling 67 ERK phosphorylation 67 serotonin receptor 67 oncoprotein 67 inflammatory cytokine 67 phosphorylate 67 selectively binds 67 immune modulating 67 Akt 67 nanomolar range 67 TRAIL receptors 67 ß catenin 66 Mcl 1 66 oncogenic 66 IGF 1R 66 PI3 kinase 66 histone deacetylases 66 CGRP 66 anticancer activity 66 PTPN# 66 erythropoietin receptor 66 phosphorylates 66 kinase pathway 66 interferon IFN 66 heme oxygenase 66 SOD1 66 Factor VEGF 66 immune modulator 66 acetylcholinesterase 66 p# MAPK 66 Aß 66 N cadherin 66 cell adhesion molecule 66 inhibitory effect 66 hTERT 66 CTGF 66 mediated apoptosis 66 ENaC 66 5 HT4 receptor 66 TTR gene 66 inhibitory activity 66 5 HT2A serotonin 66 isoenzyme 66 RANK Ligand 66 RAS RAF MEK 66 myeloid derived 66 proto oncogene 66 M1 muscarinic 66 immunomodulatory 66 selective modulator 66 Foxp3 66 cyclin dependent kinase inhibitor 66 CD# [002] 66 Bcl XL 66 intracellular signaling 66 receptor PPAR 66 HGS ETR2 66 immunomodulatory effects 66 miR #a [001] 66 tubulin 66 tubulin binding 66 mRNA expression 66 poly ADP ribose polymerase 66 somatostatin 66 thromboxane A2 66 Th1 type 66 MAPK 66 aromatase 66 apoptotic 66 dose dependently 66 receptor agonists 66 mTOR inhibitors 66 catalase 66 FGFR 66 4E BP1 66 MMP9 66 5 HT1A 66 elastase 66 PLA2 66 extracellular signal 66 phosphatidylinositol 66 c myc 66 eIF4E 66 leukemic cell 66 selective agonist 66 p#NTR 66 leukocyte adhesion 66 Factor Receptor 66 proinflammatory 66 inflammatory mediators 66 receptor signaling 66 NFkappaB 66 tumor suppressive 66 HCV protease 66 IAP inhibitor 66 UCP2 66 upregulating 66 Flt3 66 PEDF 66 Epothilones 66 ERK signaling 66 1α 66 CDK inhibitor 66 receptor inhibitor 66 interleukins 66 receptor blocker 66 tyrosine kinase 66 p# activation 66 type glutamate receptor 66 D aspartate 66 cytotoxicity 66 receptor kinase 66 overactivation 66 TNFa 66 COX2 66 estrogen receptor beta 66 fibrinolytic 66 downregulation 65 5 HT6 receptor 65 monocyte chemotactic protein 65 cytostatic 65 potently inhibit 65 RANKL 65 anti fibrotic 65 65 BCR ABL 65 CTLA 4 65 irreversible inhibitor 65 cyclic AMP cAMP 65 heterodimers 65 histone acetylation 65 V#F mutation 65 HDACi 65 protein tyrosine phosphatase 1B 65 receptor subtype 65 mTOR pathway 65 cyclase 65 inverse agonist 65 tumor suppressor proteins 65 inhibiting tumor 65 tumor vasculature 65 Protein Kinase C 65 apoptotic pathway 65 LRP5 65 FGFR1 65 HER3 65 anti CD3 65 polyamine 65 JAK2 65 HDAC6 65 pertussis toxin 65 PHD2 65 prostanoid 65 Skp2 65 LPS induced 65 anti amnesic 65 cAMP 65 TrkB 65 dopamine D2 65 p# subunit 65 thioredoxin 65 prostaglandin D2 65 Nampt 65 hypermethylation 65 vasodilatory 65 gastrin 65 EGFR tyrosine kinase inhibitors 65 receptor subtypes 65 cyclin D1 65 IFN alpha 65 adenylate cyclase 65 heparanase 65 EGFR signaling 65 cytolytic 65 NPD1 65 PI3K/mTOR 65 NF κB 65 secretory phospholipase A2 sPLA2 65 vimentin 65 PPAR gamma receptor 65 vascular endothelial cells 65 MEK1 65 p# alpha [001] 65 MEK ERK 65 nanomolar 65 thrombin receptor 65 upregulates 65 glucokinase 65 downregulates 65 Tyrima 65 serine protease 65 Tubulin 65 Abl 65 casein kinase 65 NKX#.# 65 transcriptional activation 65 downregulated 65 Tie2 65 PI3K inhibitor 65 Aâ 65 tryptase 65 glycogen synthase kinase 65 pyrimidine 65 EpCAM 65 potent cytotoxic 65 GSTP1 65 phospho 65 peroxynitrite 65 matrix metalloproteinases 65 LDL receptor 65 JAK2 enzyme 65 secreted protein 65 serotonin reuptake 65 adhesion molecule 65 dopamine reuptake 65 NF kappaB activation 65 E3 ligase 65 phosphorylated 65 anti inflammatory cytokine 65 nicotinic acetylcholine receptor 65 cathepsin B 65 MMP2 65 receptor gamma 65 Overexpression 65 E selectin 65 ornithine decarboxylase 65 alpha subunit 65 CD# CD# 65 mu opioid receptor antagonist 65 CCR9 65 downstream effector 65 calcitriol 65 anaphase promoting complex 65 potentiating 65 ceramide 65 anti neoplastic 65 cyclin dependent kinase 65 Kupffer cells 65 TGF alpha 65 pleiotropic 65 #beta 65 p# mitogen activated 65 FLT3 64 STAT3 64 HLA DR 64 enzyme inhibitor 64 active metabolite 64 IFN gamma 64 upregulate 64 cyclic adenosine monophosphate cAMP 64 MUC1 64 ON #.Na 64 Hedgehog signaling 64 peroxidase 64 prostaglandin synthesis 64 FKBP# 64 granulocyte macrophage colony stimulating 64 neuronal dysfunction 64 DNA methyltransferases 64 FGF# 64 selectively inhibit 64 presynaptic 64 antitumor activity 64 proteases 64 cytochrome P 64 transgene expression 64 LRP6 64 amyloid β 64 PC# cells 64 molecularly targeted 64 antisense inhibition 64 VEGF inhibitors 64 PAK1 64 Smad3 64 DFMO 64 TGF beta pathway 64 1beta 64 β catenin 64 EGFRvIII 64 enzymatic activity 64 LNCaP cells 64 receptor agonist 64 miR #a [002] 64 cholecystokinin CCK 64 antiinflammatory 64 isoenzymes 64 mGluR 64 ERBB2 64 proteolysis 64 transcriptional repressor 64 erlotinib Tarceva ® 64 HER2/neu 64 FGFs 64 IGFBP 64 HDAC inhibitors 64 Cyclin E 64 antioxidant enzyme 64 S#P# 64 factor TNF 64 Th1 cells 64 Tumor necrosis factor 64 IFN α 64 PKC inhibitors 64 pan HDAC inhibitor 64 Cathepsin B 64 thrombopoietin 64 acetylcholinesterase AChE 64 ubiquitination 64 noradrenergic 64 Vidofludimus 64 HDACs 64 MetAP2 64 serotonergic 64 neuroprotective properties 64 antimetastatic 64 receptor tyrosine kinase inhibitor 64 PKC isoforms 64 Rap1 64 NQO1 64 NFkB 64 autophagic 64 T#I [002] 64 CagA 64 cis retinoic acid 64 nitrotyrosine 64 hedgehog pathway 64 secretase 64 B7 H1 64 selective kinase inhibitor 64 agonism 64 acetylcholine receptor 64 triggers apoptosis 64 leukotriene 64 NF kappaB 64 Preclinical studies suggest 64 osteopontin 64 cathepsins 64 cyclin dependent kinases CDKs 64 GSK3B 64 cyclin dependent kinases 64 calcineurin 64 orally administered inhibitor 64 pRb 64 synuclein 64 Hedgehog pathway 64 Abeta# 64 NO synthase 64 PI3K/Akt pathway 64 tyrosine phosphorylation 64 AKT1 64 diphosphate 64 heme oxygenase 1 64 TGF b 64 Lp PLA 2 64 5 HT1A receptor 64 fatty acid oxidation 64 Src 64 cytochrome P# 64 glutamatergic 64 erythropoietic 64 Rac1 64 constitutively activated 64 BACE1 64 adenosine diphosphate ADP 64 Fibroblast Growth Factor Receptor 64 osteoclastic 64 costimulation 64 histone deacetylase inhibitors 64 TMEM#B 64 PI3K pathway 64 receptor partial agonist 64 thioredoxin reductase 64 redox active 64 Phosphorylation 64 chemokine receptor 64 antioxidant enzymes 64 GRK2 64 phosphoprotein 64 VE cadherin 64 interleukin IL -# 64 CLL cells 64 deacetylase 64 PLK1 64 potent anti angiogenic 64 beta amyloid peptide 64 FGFR2 64 CCR1 64 S1P 64 AChE 64 reductase 64 MT1 MMP 64 opioid receptor 64 CYP#B# 64 triphosphate 64 Wnt beta catenin 64 pharmacological inhibition 64 protein encoded 64 plasma fibrinogen 64 cytotoxic 64 lytic 64 fatty acid synthase 64 BH3 64 adrenergic receptors 64 TGF beta 64 5 lipoxygenase 64 IFN g 64 5HT 64 Notch receptor 64 FGF receptor 64 Lyn kinase 64 FUS1 64 naturally occurring molecule 64 excitotoxic 64 GSK3 64 CYP# [002] 64 Tumor Necrosis Factor 64 kinase PI3K Akt pathway 64 CB2 receptor 64 cell adhesion molecules 64 Angiotensin II 64 FGFR3 64 thymidylate synthase TS 64 inhibited tumor 64 BAL# [001] 64 EGFR 64 antidiabetic 64 paracrine 64 GSK 3ß 64 glutamate receptors 64 mTOR signaling 64 B Raf 64 nucleoside analog 64 protein tyrosine kinase 64 D aspartate NMDA receptor 64 platelet aggregation 64 Î ² 64 p# Shc 64 histone deacetylation 64 Bcl 2 64 osteocalcin 64 incretin 64 cytokine receptor 64 c Src 64 HGF 64 β amyloid 64 cytochrome P# #A# 64 kinase inhibitor 64 gamma tocotrienol 64 XIAP 64 tyrosinase 63 EP1 receptor 63 mitochondrial enzyme 63 potent inhibitory 63 sunitinib Sutent ® 63 bleomycin 63 gamma secretase 63 microglial 63 myeloma cells 63 GPx 63 calcitonin gene related 63 imatinib Gleevec ® 63 hydrolase 63 potent antibacterial 63 endothelial activation 63 transcriptionally 63 H#K#me# 63 DNA intercalator 63 colorectal carcinoma 63 synthase TS 63 pro inflammatory cytokines 63 osteoprotegerin 63 leukotrienes 63 bcl 2 63 IGF IR 63 vasoactive 63 cytosolic 63 eotaxin 63 inhibit tumor 63 autocrine 63 interleukin 1β 63 ABCB1 63 activated lymphocytes 63 Th2 63 HDAC enzymes 63 HSP# 63 SETDB1 63 ß amyloid 63 osteoclast activity 63 microsomal 63 investigational humanized monoclonal antibody 63 Epidermal Growth Factor Receptor 63 histone H3 63 antitumoral 63 bradykinin 63 GAPDH 63 vascular disrupting agent 63 PTHrP 63 intracellular accumulation 63 CDK5 63 apoptosis proteins 63 Treg cell 63 constitutively 63 topoisomerase 63 costimulatory 63 PPAR gamma 63 Hsp# inhibitors 63 dopamine transporter 63 neuronal nitric oxide synthase 63 delta isoform 63 prolyl 63 gamma secretase inhibitor 63 KLF4 63 neurturin 63 TNFR 63 HER2 overexpression 63 Rho GTPase 63 glucocorticoid 63 IFN ß 63 PTP1B 63 mTORC1 63 reversible inhibitors 63 derived neurotrophic factor 63 Ki# 63 NFAT 63 CEACAM1 63 substrate specificity 63 substrates inhibitors 63 lipoxygenase 63 dasatinib Sprycel 63 E cadherin 63 glial cell 63 beta adrenergic 63 overexpressing 63 leukotriene pathway 63 GPR# [002] 63 cytokine IL 63 proinflammatory cytokines 63 metalloprotease 63 angiopoietin 63 leukotriene B4 63 thyroid hormone receptor 63 intratumoral injection 63 alpha#beta# integrin 63 lipoprotein lipase 63 dimeric 63 hydrolases 63 multikinase inhibitor 63 induced apoptosis 63 CCL2 63 adipogenesis 63 cytokine interleukin 63 regulated kinase ERK 63 CD#b 63 AMACR 63 Gleevec resistant 63 TLR2 63 FOXO1a 63 chemokine 63 D aspartic acid 63 proteasome inhibitors 63 muscarinic receptors 63 oncoproteins 63 TET2 63 ErbB 63 MAP kinases 63 CDK4 63 PPAR peroxisome proliferator activated 63 agonists antagonists 63 PKC inhibitor 63 binding affinity 63 AMPA receptor 63 Akt phosphorylation 63 SOCS3 63 potent inhibitors 63 protein CETP 63 AZD# ARRY # 63 tyrosine kinases 63 aberrant activation 63 K + ATPase 63 VEGFR 63 nucleolin 63 microvessel density 63 ERK activation 63 #ME# 63 flavopiridol 63 ubiquitin ligase 63 WT1 63 erythropoiesis 63 tumor suppressor protein 63 P selectin 63 coactivator 63 NS#/#A protease 63 PPAR γ 63 transmembrane receptor 63 plasmacytoid dendritic cells 63 promoter methylation 63 RIP1 63 intracellular uptake 63 potentiation 63 1alpha 63 EGFR HER2 63 c myc gene 63 mitotic progression 63 5 hydroxytryptamine 63 VEGF receptors 63 Fas ligand 63 Her-2/neu 63 microtubule targeting 63 apoptotic cell 63 OXi# 63 CD4 + CD# 63 PKCi 63 TGF ß1 63 rhIL 7 63 HCV replication 63 Macrophage 63 Blinatumomab 63 PKM2 63 neurotrophic factors 63 polyamines 63 Raf MEK ERK 63 demethylation 63 kinase PI3K 63 cisplatin resistant 63 glycosyltransferase 63 alkylating agent 63 miR #b [001] 63 Dysregulation 63 Nrf2 63 NADPH oxidase 63 LPA1 63 enzyme inhibitors 63 tyrosine hydroxylase 63 NK1R 63 immune modulatory 63 Rab5 63 TCF#L# 63 ERK5 63 avidin 63 superoxide 63 TGFβ 63 pDCs 63 protein phosphatase 63 fibrotic 63 apoptosis induced 63 IMPDH 63 VEGF induced 63 anti atherogenic 63 IL 1Ra 63 Hedgehog signaling pathway 63 NMDAR 63 antiangiogenic activity 63 T#M 63 alpha Gal 63 depsipeptide 63 vasodilatation 63 FK# 63 receptor antagonists 63 ß1 63 effector functions 63 IGFBP2 63 EZH2 63 histone deacetylase 63 Immunohistochemical analysis 63 decarboxylase 63 specific lectin receptors 63 anti angiogenic agent 63 Src kinase 63 orally bioavailable 63 effector cells 63 VEGF vascular endothelial 63 PKC# 63 macrophage colony stimulating 63 Symadex 63 lysosomal 63 endothelial nitric oxide 63 GSTT1 63 VIPR2 63 tyrosine kinase inhibitor 63 extracellular domain 63 mineralocorticoid receptor 63 seliciclib 62 Cdc# 62 dehydrogenase 62 Anti Tumor 62 arginase 62 PECAM 1 62 alpha7 62 interleukin IL -6 62 SCD1 62 lysophosphatidic acid LPA 62 Rho kinase 62 TAp# 62 endoplasmic reticulum stress 62 mecamylamine 62 melanocyte stimulating hormone 62 K ras mutations 62 polyadenylation 62 Wnt signaling 62 SGLT2 62 basophils 62 antibody mediated 62 thymidylate synthase 62 PC3 cells 62 azacytidine 62 GPC3 62 BMAL1 62 integrin 62 5 HT2A inverse 62 CD# monoclonal antibody 62 effector memory 62 lyase 62 collagen synthesis 62 SERMs 62 MTHFR 62 neuroinflammation 62 bone resorption 62 estramustine 62 cysteine 62 protein tyrosine phosphatase 62 prostaglandin E2 62 downregulating 62 HPA axis 62 c Myc 62 RANK ligand 62 alpha folate receptor 62 signal transduction inhibitor 62 microtubule dynamics 62 oligomerization 62 HbF 62 phagocyte 62 CD# receptor 62 retinoic acid 62 Smad7 62 costimulatory molecules 62 HER2 receptors 62 interleukin IL 62 Interferon gamma 62 Sp1 62 telomerase reverse transcriptase 62 fast skeletal troponin 62 VEGFb 62 B7 H4 62 NR2B selective 62 RANTES 62 colony stimulating factor 62 Pgp 62 PKC beta 62 oxidative enzymes 62 inhibit angiogenesis 62 Integrin 62 signaling cascades 62 oxytocin receptor 62 ApoB 62 3' UTR 62 T#I mutant 62 proteasome inhibitor 62 PDE4 62 D2 receptor 62 ErbB3 62 GMX# 62 inhibitory neurotransmitters 62 antisense inhibitors 62 excitatory neurotransmitter glutamate 62 Preclinical studies 62 amyloid beta peptides 62 Kinoid 62 nucleoside analogues 62 neuroblastoma cells 62 ErbB4 62 endoxifen 62 #beta HSD1 62 muscarinic receptor 62 ACE2 62 Hypoxia Inducible Factor 62 alkaline phosphatase ALP 62 osteoclast 62 UsiRNAs 62 glutamyl 62 bioactive lipids 62 allosteric 62 metalloproteinase 62 GHRH 62 FGF2 62 IKK 62 neuro protective 62 oxidase 62 suppressor cells 62 HDAC inhibition 62 inhibits protein synthesis 62 small molecule inhibitors 62 oral prodrug 62 TLR8 62 CD#c 62 COX enzymes 62 E3 ubiquitin ligase 62 dopaminergic 62 MCF7