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(Click for frequent words.) 75 Nedd4 74 immunoregulatory 74 MAPK pathway 73 serine protease 73 androgen receptor AR 73 uPAR 73 FGFs 73 mitogen activated protein kinase 72 oncogenic 72 constitutively expressed 72 selective inhibition 72 tropomyosin 72 phosphorylates 72 potent inhibitors 71 IL 1ß 71 MT1 MMP 71 cytokine signaling 71 catenin 71 phosphate S1P 71 micro RNAs 71 PPARγ 71 metabolic enzymes 71 calcineurin 71 tyrosine phosphorylation 71 activin 71 beta subunit 71 protein kinases 71 deacetylation 71 tRNA synthetase 71 evolutionarily conserved 71 thrombospondin 71 virulence genes 71 eNOS 71 cathepsins 71 ERK1 71 estrogen receptor beta 71 glycolipids 71 pRb 71 SIRT2 70 protein tyrosine phosphatases 70 upregulation 70 E3 ligase 70 cyclin dependent kinase inhibitor 70 glucocorticoid receptor 70 constitutively active 70 pleiotropic 70 ERK1 2 70 cyclins 70 Rho GTPases 70 p# MAPK 70 S1P 70 E#F# 70 phosphatidylinositol 3 70 Eg5 70 serine threonine kinase 70 PDGFR 70 cystic fibrosis transmembrane conductance 70 casein kinase 70 transcriptional activation 70 Kv#.# 70 cell adhesion molecules 70 γ secretase 70 inverse agonist 70 cell adhesion molecule 70 IL #p# 70 KLF4 70 TGF ß 70 somatostatin 70 mitogenic 70 VE cadherin 70 FasL 70 PAK1 70 TGF β 70 Smad3 70 MAPK 70 FOXO3a 70 aberrantly activated 70 prostaglandin synthesis 70 acetylcholine receptor 70 COX2 69 LRP6 69 Th2 69 TNFalpha 69 Wnt signaling pathway 69 HDACs 69 vimentin 69 Arp2 3 69 mutant huntingtin protein 69 FGFR3 69 homodimers 69 CCR9 69 GSK 3ß 69 ENaC 69 oncoproteins 69 PI3K Akt 69 adhesion molecule 69 genes encoding 69 downregulation 69 eotaxin 69 EGFR signaling 69 ubiquitylation 69 NFκB 69 NKG2D 69 pDCs 69 Upregulation 69 ERK2 69 regulating gene expression 69 signaling pathway 69 proto oncogene 69 IL 1β 69 transactivation 69 LRP5 69 c MET 69 Phosphorylation 69 TNFα 69 substrate specificity 69 β catenin 69 ERK signaling 69 TMEM#B 69 MAP kinase 68 anti apoptotic 68 c myc 68 NS5A 68 matrix metalloproteinases MMPs 68 FoxO1 68 HIF 1alpha 68 endogenous ligand 68 antiapoptotic 68 USP# 68 costimulatory 68 PAR1 68 retinoic acid receptor 68 PTP 1B 68 noncoding RNAs 68 hypermethylation 68 pro apoptotic 68 HDAC2 68 glycosyltransferase 68 oncoprotein 68 guanosine 68 transcriptional regulation 68 MEK1 68 overactivation 68 protein encoded 68 prolyl 68 microRNAs miRNAs 68 glucokinase 68 proteolysis 68 receptor tyrosine kinase 68 isoform 68 autocrine 68 ubiquitin ligase 68 HBx 68 CagA 68 Notch1 68 mediated inhibition 68 transcriptionally 68 protein kinase C 68 Hedgehog signaling 68 MAPKs 68 5 lipoxygenase 68 lysosomal 68 GRP# 68 PI3 kinase 68 Notch signaling 68 transcriptional repressor 68 PKC isoforms 68 STAT3 68 Wnt pathway 68 tumor suppressors 68 PPARg 68 potent inhibition 68 Cdc# 68 cyclooxygenase 68 Androgen receptor 68 Cathepsin B 68 NFAT 68 beta amyloid peptide 68 paxillin 68 Integrins 68 Cytotoxic T 68 HIF 1α 68 coding genes 68 proteases 68 hydrolases 68 missense mutations 68 matrix metalloproteinases 68 hypoxia inducible factor 68 downregulated 68 actin cytoskeleton 68 SOD1 protein 68 PTP1B 68 NKX#.# 68 IRAK1 68 PKD1 68 histone modifications 68 neurite outgrowth 68 methyltransferases 68 C5aR 68 tumor suppressor protein 68 demethylase 68 transient receptor 68 GPR# [002] 68 GSK3B 68 FGFR1 67 VEGF receptor 67 mPGES 1 67 cellular pathways 67 catalytic subunit 67 apoE 67 JAK STAT 67 selective modulator 67 Th# cells 67 TNF α 67 tyrosine kinase 67 primary cilia 67 chemokine receptors 67 cyclase 67 Aurora kinases 67 LDL receptor 67 LIS1 67 BCL2 67 tyrosine kinase receptor 67 histone deacetylases 67 glutamate receptors 67 upregulates 67 deacetylase 67 aromatase 67 Smoothened 67 cyclin dependent kinases 67 MTHFR 67 serine proteases 67 histone deacetylation 67 NKT cells 67 mRNA expression 67 TRPV3 67 ERK pathway 67 Mcl 1 67 PIP2 67 coagulation cascade 67 alpha subunit 67 ADAM# 67 astrocytic 67 interleukins 67 signaling cascades 67 cytokine receptor 67 CXCR2 67 pyrimidine 67 chemokine receptor 67 Htt 67 FGFR2 67 miRNA expression 67 phagocytosis 67 melanocyte 67 innate immune responses 67 ligases 67 androgen receptors 67 IGF IR 67 chromatin remodeling 67 peroxisome proliferator activated 67 microRNA molecules 67 RNase L 67 peroxisome 67 serine threonine 67 phosphatase 67 cyclooxygenase COX 67 fusogen 67 overactivated 67 splice variants 67 HCV replication 67 synuclein 67 microglial activation 67 lymphoid cells 67 HMG CoA reductase 67 synthases 67 Hypoxia Inducible Factor 67 HOTAIR 67 sortilin 67 IGF 1R 67 c MYC 67 isotypes 67 JAK2 enzyme 67 iNOS 67 nAChRs 67 RANKL 67 AT1R 67 5 HT2A serotonin 67 oligomerization 67 extracellular signal 67 subcellular compartments 67 proinflammatory 67 autoreactive T cells 67 Fas ligand 67 proapoptotic 67 isoforms 67 transmembrane protein 67 NFkB 67 thrombin receptor 67 autophagic 67 CDKs 67 STAT1 67 secreted protein 67 presenilin 67 ERa 67 Akt 67 MDR1 67 oxidative phosphorylation 67 FGFR4 67 caveolin 67 RhoA 67 Macrophage 67 DISC1 67 Factor Receptor 67 phosphoprotein 67 Oct4 67 ubiquitination 67 myeloid cells 67 intracellular signaling 67 Cyclin E 67 serotonin receptor 66 epigenetic alterations 66 NF kappaB pathway 66 XBP1 66 FGF2 66 chemokine 66 Stat3 66 Overexpression 66 PIP3 66 mediated apoptosis 66 Notch receptor 66 neuromuscular junction 66 fibril formation 66 Rab5 66 dephosphorylation 66 nitric oxide synthase 66 HDAC 66 Pten 66 Akt signaling 66 siRNA mediated 66 4E BP1 66 cyclooxygenase 2 66 miR #a [001] 66 SGLT2 66 acyltransferase 66 protein phosphorylation 66 MDM2 66 protein tyrosine kinase 66 PPARgamma 66 thyroid hormone receptor 66 secretase 66 gamma secretase 66 metalloproteinase 66 antibody mediated 66 cytoplasmic domain 66 DLC1 66 oncogenesis 66 neuronal differentiation 66 renal fibrosis 66 5 HT2A receptor 66 cysteine protease 66 plasma kallikrein 66 cysteine residues 66 Rho GTPase 66 untranslated regions 66 tumor suppressor PTEN 66 nicotinic acetylcholine receptor 66 druggable target 66 cell signaling pathways 66 PDE#A 66 osteoblast 66 V#F mutation 66 Treg cells 66 muscarinic receptors 66 BMP signaling 66 kinase pathway 66 cytolytic 66 receptor gamma 66 Wnts 66 BMAL1 66 TGF beta 66 calpain 66 tyrosine kinases 66 Hedgehog signaling pathway 66 posttranslational modification 66 glycosylated 66 sequence homology 66 Sertoli cell 66 FGF# 66 downstream effector 66 prostaglandin E2 PGE2 66 FUS1 66 cytokine receptors 66 TAp# 66 Src 66 #beta HSD1 66 CXCL# 66 glycosylation 66 plasminogen 66 TGF b 66 chloride channels 66 isoenzymes 66 NF κB 66 histone H3 66 CEACAM1 66 adenylate cyclase 66 ß catenin 66 SUMOylation 66 Hh 66 metalloprotease 66 HepG2 cells 66 cadherin 66 c Myb 66 adrenoceptor 66 viral proteins 66 secretory pathway 66 DNA methyltransferases 66 innate immune response 66 thymidylate synthase TS 66 CDK5 66 estrogen receptor alpha 66 dimerization 66 protein misfolding 66 Cdc7 66 IFNg 66 methyltransferase 66 glycogen synthase kinase 66 hematopoiesis 66 immunodominant 66 integrin 66 UCP2 66 synaptogenesis 66 peroxidase 66 caveolin 1 66 peroxisomal 66 downregulates 66 tumor suppressive 66 N Myc 66 EZH2 66 Runx2 66 Janus kinase 66 fatty acid synthase 66 synaptic transmission 66 regulates gene expression 66 leukocyte adhesion 66 kinase enzymes 66 Jhdm2a 66 Bcl 66 protein phosphatase 66 NF kB pathway 66 beta catenin 66 epigenetic modification 66 metalloproteases 66 receptor subtype 66 receptor activation 66 hedgehog pathway 66 PGC 1α 66 biogenesis 66 histone H4 66 p# alpha [001] 66 TRAIL induced apoptosis 66 MMPs 66 PTPN# 66 hydrolase 66 microRNA miR 65 cAMP signaling 65 myofibroblasts 65 acetylation 65 AMPA receptor 65 muscarinic 65 phosphoinositide 3 65 CCR2 65 endogenous ligands 65 reductase 65 RNA polymerases 65 non coding RNA 65 ErbB4 65 SOD1 65 Rb#/p# 65 CB2 receptor 65 Skp2 65 IKKß 65 cytoprotective 65 Th1 cells 65 HCV protease 65 superoxide dismutase 65 Hsp# [001] 65 adipogenic 65 beta globin gene 65 mTOR pathway 65 TNF receptors 65 oncogenic transformation 65 Hh pathway 65 dimeric 65 CIB1 65 lysophosphatidic acid LPA 65 kinase PI3K 65 CB1 receptor 65 lymphotoxin 65 GLI1 65 dysregulated 65 ncRNAs 65 PI3K pathway 65 tumorigenicity 65 F actin 65 hyperactivation 65 β1 65 tumor suppressor gene 65 IFN γ 65 cofactor 65 Foxp3 65 PPAR gamma 65 PTHrP 65 protein interleukin 65 EGF receptor 65 metalloproteinases 65 carboxyl terminal 65 ornithine decarboxylase 65 CD1d 65 syntaxin 65 acetyltransferase 65 Rap1 65 beta1 integrin 65 FGFR 65 ERBB2 65 selectively inhibits 65 proteolytic 65 D aspartic acid 65 cyclin D1 65 epithelia 65 caspases 65 membrane receptors 65 WNK1 65 inflammatory cytokines 65 integrins 65 vascular endothelial cells 65 retinoblastoma protein 65 phospho 65 phosphatidylinositol 65 ectopic expression 65 cell signaling pathway 65 mechanotransduction 65 geldanamycin 65 homeobox gene 65 antimicrobial peptide 65 Hedgehog pathway 65 homolog 65 TGF beta signaling 65 Vps# 65 proteoglycan 65 TGF beta pathway 65 adrenergic receptors 65 beta arrestin 65 receptor kinase 65 receptor signaling 65 Kinases 65 replicon 65 miR #b [002] 65 IGF1R 65 DNMT1 65 activating mutations 65 heterodimers 65 selective inhibitors 65 phosphoinositide 65 promoter methylation 65 sphingolipid 65 sphingosine 1 65 mitogen activated protein kinases 65 Kupffer cells 65 palytoxin 65 autoreactive 65 p# mitogen activated 65 TGF beta1 65 IGFBP2 65 peptidic 65 IMPDH 65 polyadenylation 65 induce apoptosis 65 voltage gated 65 inhibitory effects 65 VIPR2 65 chitinase 65 LKB1 65 matrix metalloproteinase 65 cyclic nucleotide 65 pharmacological inhibition 65 small molecule inhibitors 65 IRE1 65 adrenocortical 65 copper zinc superoxide 65 protein secreted 65 chromatin structure 65 adrenergic receptor 65 folate metabolism 65 lipoxygenase 65 XL# inhibits 65 eukaryotic cells 65 EphA2 65 myeloid derived 65 Fibroblast 65 acyl CoA 65 mTOR signaling 65 RANK Ligand 65 GABAA receptors 65 cannabinoid receptor 65 occludin 65 c myc gene 65 inhibits protein synthesis 65 FLT3 65 Th1 65 mTORC1 65 Protein Kinase C 65 RAS RAF MEK 65 cytokine 65 Hfq 65 exocytosis 65 outer membrane proteins 65 epithelial tissues 65 genotoxic stress 65 pro angiogenic 65 receptor inhibitor 65 SWI SNF 65 MMP2 65 transferrin receptor 65 androgen receptor 65 selenoproteins 65 cytotoxin 65 TRPV4 65 adenosine receptor 65 S#K# 65 mimetics 65 cAMP 65 apoptotic pathway 65 phosphorylate 65 homodimer 65 signaling pathways 65 constitutively activated 65 fatty acid biosynthesis 65 NADPH oxidase 65 gene encodes protein 65 ncRNA 65 apoptosis pathways 65 epigenetically 65 cotransporter 65 GNAQ 65 nAChR 65 selectively inhibited 65 partial agonists 65 epigenetic mechanisms 65 primary cilium 65 effector cells 65 MDSCs 65 germline mutations 65 Transcription factors 65 mTOR 65 signaling cascade 65 glutamate receptor 65 cholesterol homeostasis 65 oxidase 65 posttranslational modifications 65 Rab# 65 C1q 65 TrkA 65 MAP kinases 65 intracellular proteins 65 Lyn kinase 65 overexpressing 65 tRNA synthetases 64 APOBEC3G 64 Oncogenic 64 peptide hormone 64 leptin receptor 64 CXCR4 64 neuronal nitric oxide synthase 64 GTPase 64 Abeta peptide 64 subcellular localization 64 transcriptional machinery 64 Mesenchymal 64 forkhead 64 signal transduction 64 enzyme COX 64 SIRT6 64 antigenic epitopes 64 Rho kinase 64 TRPV1 receptors 64 coactivator 64 RNA binding 64 5 HT1A 64 Polymorphisms 64 inhibitory 64 neutrophil recruitment 64 gene locus 64 anterior pituitary 64 cytokine IL 64 thioredoxin 64 TSC1 64 Src kinase 64 neurotrophic 64 lymphoid organs 64 ribosomal protein 64 eIF4E 64 Pax6 64 NR2B subunit 64 Aurora kinase 64 circadian clock genes 64 protein tyrosine phosphatase 1B 64 HIF 1a 64 lymphocyte activation 64 intracellular bacteria 64 neuroinflammation 64 Vpu 64 BMP2 64 IGFBP 64 Flt3 64 histone deacetylase 64 SCD1 64 FOXP3 64 replicase 64 signal transduction pathways 64 hypothalamic pituitary 64 p#NTR 64 phosphorylated 64 CTLA 4 64 IGFBP 3 64 tubulin 64 protein p# 64 peptide antigens 64 lyase 64 non coding RNAs 64 TSP1 64 receptor ligand 64 induces apoptosis 64 cyclic AMP cAMP 64 osteoclast 64 Akt activation 64 ARF1 64 histone acetylation 64 kinases 64 Akt1 64 ADAMTS# 64 histone deacetylase HDAC 64 Aβ 64 JNK1 64 MAP kinase pathway 64 serpin 64 IL 1beta 64 TLR8 64 steroidogenic 64 Abl 64 N methyl 64 small molecule defensin 64 adrenal hormone 64 biosynthesis 64 aminopeptidase 64 gene rearrangements 64 triphosphate 64 Sp1 64 selective inhibitor 64 evolutionary conserved 64 mda 7 64 HER2 HER3 64 signaling molecules 64 oligomeric 64 TXNIP 64 IFN gamma 64 Huntingtin 64 basophils 64 upregulating 64 Syk 64 tumorigenic 64 ERalpha 64 mGluRs 64 reversible inhibitor 64 p#Kip# 64 cholecystokinin CCK 64 CCL5 64 Clusterin 64 Cx# [001] 64 COX enzymes 64 adipogenesis 64 histone demethylase 64 telomerase reverse transcriptase 64 Transcriptional 64 receptor molecule 64 tumor suppressor genes 64 H#K# [001] 64 factor HGF 64 mutated protein 64 polyamine 64 DGAT1 64 Lrp5 64 P#X# receptor 64 T lymphocyte 64 myeloma cells 64 IgG1 64 effector T 64 64 ß1 64 microtubule dynamics 64 Activating mutations 64 constitutively 64 cofactors 64 adipocyte 64 small molecule inhibitor 64 mTOR inhibitors 64 inflammasome 64 tumorigenesis 64 STIM1 64 c myb 64 ganglioside 64 messenger molecule 64 Epidermal Growth Factor Receptor 64 aldose reductase 64 receptor PPAR 64 amyloid fibrils 64 HDACi 64 monocytes macrophages 64 small molecule agonists 64 microglial 64 TERT 64 genes encode proteins 64 receptor subtypes 64 osteopontin 64 sGC 64 NR#A# 64 anaphase promoting complex 64 monocyte 64 ABCA1 64 acetylcholinesterase 64 SOCS3 64 steroidogenesis 64 PTEN gene 64 alternatively spliced 64 immune modulator 64 axon guidance 64 potent inhibitor 64 perivascular 64 transgenic mice expressing 64 cofilin 64 melatonin receptor 64 RNA silencing 64 AhR 64 calcium homeostasis 64 thrombopoietin 64 HDAC3 64 cyclic peptide 64 T#M 64 CYP#B# 64 miRNAs 64 CHD5 64 effector molecules 64 Cyclin D1 64 NF kappaB activation 64 preferentially bind 64 osteocalcin 64 ras gene 64 mitogen activated protein 64 tubulin polymerization 64 oncogenic proteins 64 Interferon gamma 64 polypeptides 64 neuronal dysfunction 64 RNAi pathway 64 ER alpha 64 binding proteins 64 Factor VEGF 64 glucocorticoid receptors 64 immunomodulatory effects 64 tumor suppressor 64 SH2 B 64 DLX5 64 arginase 64 amyloidogenic 64 SGK1 64 fibrogenesis 64 inducible nitric oxide synthase 64 amine oxidase 64 haematopoietic 64 perilipin 64 Prox1 64 esterase 64 DNA hypermethylation 64 EF Tu 64 S nitrosylation 64 lysine residues 64 kinase domain 64 proximal tubule 64 PKC inhibitors 64 factor receptor FGFR 64 vesicle formation 64 cytokines IL 64 rRNA 64 SOX9 64 TORC2 64 Histone 64 tumor microenvironment 64 TGFß 64 TGF alpha 64 5 HT4 receptor 64 antisense oligonucleotide 64 transmembrane 64 neuropilin 64 lymphoid tissue 64 HER3 64 IL #R 64 BMP4 64 cytochrome 64 Wnt beta catenin 64 c Myc 64 nicotinic receptor 64 inducible 64 endogenous retroviruses 64 targeting CD# 64 Dpp 64 sRNA 63 CCL# 63 JAK3 63 retinoic acid 63 Smad 63 resistin 63 gene polymorphisms 63 gene encodes 63 morphogen 63 FKBP# 63 pyrimidines 63 inflammatory cytokine 63 p#/CBP 63 DARPP 63 CatB 63 Th2 cytokines 63 kinase inhibition 63 NOTCH1 63 phospholipase A2 63 cyclin E 63 E3 ubiquitin ligase 63 PI3K signaling 63 OCT4 63 #HT#A 63 poly ADP ribose polymerase 63 ribosomal proteins 63 K + ATPase 63 enolase 63 mTOR mammalian target 63 Wnt signaling 63 amino terminal 63 Smurf1 63 biochemical mechanisms 63 proteinases 63 endonuclease 63 kallikrein 63 neurofibromin 63 PON1 63 tetramer 63 inhibit angiogenesis 63 IL#R 63 Cadherin 63 multiprotein complex 63 noncoding RNA 63 interferon IFN 63 Î ² 63 PIK3CA 63 cytidine 63 PGE2 63 neuroligins 63 cyclin dependent kinases CDKs 63 regulate gene expression 63 Klf4 63 decarboxylase 63 mitochondrial respiration 63 plasmacytoid dendritic cells 63 SOD2 63 PKM2 63 immunoreactivity 63 modulatory 63 MEK ERK 63 c KIT 63 protein conformation 63 tetherin 63 CTGF 63 p# tumor suppressor 63 methyl D aspartate 63 P2X 63 cypin 63 hydroxylase 63 selectively binds 63 S6K 63 GABAergic 63 defensin 63 lipid homeostasis 63 inhibit viral replication 63 P selectin 63 chaperone protein 63 keratinocyte 63 apoptosis induced 63 mutational status 63 mucins 63 miR# 63 GPx 63 epigenetic modifications