orphan GPCRs

Related by string. * orphaned . Orphans . Orphaned . orphans . orphaning . Orphan . ORPHAN . ORPHANS : Little Orphan Annie . widows orphans . Swedish Orphan Biovitrum . Orphan Drug Designation . Orphan Drug designation . FDA Orphan Drug . Malawi orphans / : coupled receptors GPCRs . coupled receptor GPCR . GPCR ligands . coupled receptors GPCR . GPCR targets . Receptors GPCRs . GPCR assays * *

Related by context. All words. (Click for frequent words.) 63 GPR# [002] 62 therapeutic monoclonal antibodies 62 GPCRs 61 VEGF receptor 61 small molecule inhibitors 61 splice variants 61 drugable targets 61 mAbs 60 siRNA therapeutics 60 dAbs 60 CCX# 60 AEG# 60 JAK3 60 druggable targets 60 siRNA therapeutic 60 antisense drugs 60 protein kinase inhibitor 60 glucagon receptor 60 anticancer therapeutics 60 prodrugs 59 HCV polymerase 59 tiapamil 59 recombinant antibodies 59 Protein Kinase C 59 kinase inhibitors 59 PDGF receptor 59 GPCR targets 59 integrin receptors 59 FLT3 59 peptide ligands 59 rxRNA compounds 59 interferon lambda 59 histone deacetylase HDAC 58 eTag assays 58 GPCR 58 siRNAs targeting 58 glycosylated 58 ALN TTR 58 biased ligands 58 Stapled Peptide 58 AV HALT 58 preclinical compounds 58 CEQ# 58 ETBs 58 ghrelin receptor 58 proteasome inhibitors 58 P#X# 58 multiplexed assays 58 NEUGENE 58 Chemokine Receptor 58 HDACs 58 Symadex 57 adenosine receptor 57 metabotropic glutamate receptors 57 antagomirs 57 CXCR4 receptor 57 TLR8 57 proprietary LNA 57 antisense inhibitors 57 vivo potency 57 HIV integrase inhibitors 57 histone deacetylase 57 rxRNA 57 Receptors GPCRs 57 DXL# 57 cytokine receptor 57 hormone gastrin 57 fusion proteins 57 Janus Kinase 57 MAPK pathway 57 polymerase inhibitors 57 protein kinases 57 IAP inhibitors 57 romazarit 57 mRNA antagonists 57 co stimulatory molecules 57 secreted proteins 57 dasatinib Sprycel 57 molecular biomarkers 57 antisense oligonucleotides 57 HuLuc# 57 miRview mets 57 Factor VIIa 57 GAP #B# 57 monoclonal antibody mAb 57 humanized antibody 56 undruggable targets 56 viral proteins 56 humanized antibodies 56 Nanobodies 56 CCR3 56 G Protein Coupled 56 small molecule defensin 56 PI3K/mTOR 56 MAbs 56 selective antagonists 56 nicotinic receptors 56 humanized monoclonal antibodies 56 PARP inhibitors 56 monoclonal antibodies MAbs 56 agonist compounds 56 cancer immunotherapies 56 HDAC enzymes 56 PGL# 56 EZN 56 Nanobodies ® 56 MEK inhibitor 56 novel peptides 56 novel peptide 56 mitotic kinesins 56 epothilones 56 epothilone 56 AMPK activators 56 methyltransferases 56 novel antiviral therapeutics 56 SAR# [002] 56 JAK2 inhibitors 56 ENMD # 56 HDAC inhibition 56 adrenergic regulation 56 adenoviral 56 OMP #M# 56 metabolic enzymes 56 LNP formulations 56 A3 adenosine receptor 56 proteasome inhibitor 56 androgen receptor AR 56 JAK2 inhibitor 56 predictive biomarkers 56 diagnostic biomarker 56 molecularly targeted 56 nucleoside analogs 56 Spiegelmers ® 56 MEK inhibitors 56 anti CD3 56 chemokine receptors 56 Nanobody 56 Janus kinase 56 virulence genes 56 Nanobody ® 56 antisense drug 56 receptor tyrosine kinase inhibitor 56 NSCLC tumors 56 TLR antagonists 56 prophylactic vaccines 55 fusion inhibitor 55 ALK inhibitors 55 Sym# 55 proprietary phage display 55 siRNA sequences 55 RNAi therapeutic 55 JAK inhibitors 55 Preclinical studies suggest 55 GeneICE 55 short hairpin RNAs 55 Phylomer ® 55 herpesviruses 55 CCR9 antagonist 55 peptide antigens 55 5 HT2C receptor 55 IAP inhibitor 55 Pharmos pipeline 55 FBPase 55 engineered RAP peptides 55 monoclonal antibodies mAbs 55 BRAF kinase 55 Anticalins 55 UsiRNAs 55 rxRNA ™ compounds 55 potent inhibitors 55 K ras mutations 55 PI3K inhibitor 55 molecular abnormalities 55 biomarker identification 55 inhibit EGFR 55 tubulin inhibitor 55 oncolytic 55 Anticalins R 55 peptidomimetic 55 KinomeScan 55 oral gallium 55 Bafetinib 55 XmAb# 55 potently inhibit 55 Fibroblast Growth Factor Receptor 55 proprietary Dicer Substrate Technology 55 transient receptor 55 alpha folate receptor 55 polyketides 55 serine protease 55 selective inhibitors 55 Tarvacin TM 55 biologic therapeutics 55 VitiGam 55 small molecule modulators 55 tumor antigens 55 anti mitotic 55 orally bioavailable 55 neuroprotective properties 55 antisense molecules 55 CB2 selective 55 Smac mimetics 55 HER1 55 lipidoid 55 HCV protease inhibitors 55 CRAC channel 55 coupled receptors GPCRs 55 TLR9 agonists 55 NS4A 55 phage display 55 SIMPLE Antibody TM 55 miR #a [002] 55 polyclonal antibody 55 IgG antibodies 55 replicon 55 Azedra 55 histone deacetylase HDAC inhibitors 55 RGB # 55 OncoVEX 55 ACTCellerate 55 nanoviricides 55 shRNA libraries 55 reverse transcriptase inhibitors 55 Notch receptors 55 ncRNA 55 Tyrima 54 chemically modified siRNA 54 myelofibrosis polycythemia vera 54 receptor alpha 54 cathepsins 54 anionic backbone 54 HDAC inhibitors 54 TRAIL receptor 54 aptamer therapeutics 54 FGFR 54 vascular disrupting agents 54 PI3K inhibitors 54 microRNA therapeutics 54 HSP# inhibitors 54 anti CD# antibodies 54 splice variant 54 histone deacetylase inhibitors 54 monoclonal antibodies 54 Adnectins 54 JAK kinases 54 immunotherapeutic 54 BCR ABL inhibitors 54 PI3 K 54 cleavable linker 54 SERMs 54 metalloenzymes 54 glucocorticoid receptor 54 #beta HSD1 54 CD# monoclonal antibody 54 humanized monoclonal antibody 54 endogenous ligands 54 antisense compounds 54 delta isoform 54 polypeptides 54 inhibit metastasis 54 targeted radiotherapeutic 54 sd rxRNA compounds 54 DsiRNA 54 Spiegelmer ® 54 preclinically 54 siRNA duplexes 54 PROfusion 54 immune modulators 54 histone deacetylase inhibitor 54 Alfacell proprietary ribonuclease 54 Adenosine Therapeutics 54 DNA methyltransferases 54 selective inhibition 54 investigational therapies 54 HTS assay 54 affinity antibodies 54 nicotinic acetylcholine receptor 54 IL# PE 54 Notch receptor 54 Gleevec resistant 54 hedgehog pathway 54 Chemokine 54 C5aR 54 BiTE 54 protein kinase inhibitors 54 microRNA miRNA 54 neuro inflammatory 54 biologic pathway 54 therapeutic monoclonal antibody 54 Aurora kinase 54 Locked Nucleic Acid LNA 54 OGeS 54 butyrylcholinesterase 54 Streptomyces bacteria 54 Litx 54 anti angiogenic drugs 54 CENP E 54 Panzem 54 siRNA mediated 54 RNA antagonist 54 Hemopurifier 54 antibody therapeutics 54 Anticalins ® 54 mAb 54 RNAi molecules 54 orally bioavailable mimics 54 glycosylation profile 54 c MET 54 Marqibo TM 54 Stapled Peptides 54 FGFR1 54 DNA plasmids 54 camptothecin 54 triphosphate 54 sd rxRNA 54 CYT# potent vascular disrupting 54 peptides 54 phosphorylated proteins 54 chemotherapeutics 54 RNAi therapeutic targeting 54 monoclonals 54 immunotoxin 54 enzyme inhibitors 54 Epidermal Growth Factor Receptor 54 Tr DNA 54 renin inhibitors 54 cellular pathways 54 monoclonal 54 cyclin dependent kinases 54 dimerization 54 selectively inhibited 54 Hsp# inhibitors 54 NS#/#A protease 54 PDE4 inhibitor 54 immunotherapeutics 54 antibody fragment 54 lentiviral vectors 54 pertussis toxin 54 kinase profiling 54 affinity ligands 54 Corgentin 54 kinases 54 RTP #i 54 THR beta agonist 53 silico prediction 53 sodium glucose transporter 53 isotypes 53 CD# CEA 53 targeting CD# 53 kinase inhibitor 53 biochemical assays 53 AvalonRx R 53 TLR9 agonist 53 human hepatocytes 53 Posiphen 53 siRNA compounds 53 AKT inhibitor 53 ddRNAi 53 aptamers 53 tyrosine kinase inhibitors 53 imatinib Gleevec 53 Seliciclib 53 K RAS 53 short interfering RNA 53 stem cell pluripotency 53 integrase inhibitor 53 SGLT2 53 thymidylate synthase TS 53 JAK1 53 adipiplon 53 protein tyrosine phosphatases 53 5 HT4 53 NNR Therapeutics 53 virulence factors 53 mertansine 53 mda 7 53 anticancer compound 53 morpholino 53 chemokine receptor 53 HDACi 53 CORT # 53 nucleic acid molecules 53 HDAC6 53 Beta catenin pathway 53 SIRT1 activators 53 mGluR2 NAM 53 NTDDS 53 receptor ligand 53 novel VDA molecule 53 CB1 antagonists 53 transferrin protein 53 Pancreate 53 small molecule activator 53 histone deacetylases 53 XmAb 53 4E BP1 53 PDE# inhibitors 53 immunological diseases 53 EGFR HER 53 inhibit viral replication 53 CCR2 receptor 53 TG# [003] 53 therapeutic peptide 53 outer membrane proteins 53 molecular imaging radiopharmaceuticals 53 Squalamine 53 oncogenic pathways 53 enzyme inhibitor 53 therapeutic antibody 53 carbohydrate polymers 53 IMC #B 53 SARMs 53 HER pathway 53 LEX System 53 small molecule activators 53 aptamer 53 Kinases 53 nucleoside analogues 53 benzimidazole 53 Integrase 53 antiviral therapeutics 53 SMARTICLES ® 53 anticancer agents 53 ErbB3 HER3 53 immune stimulatory 53 cytostatic 53 macrocycles 53 MCSP respectively 53 lipopeptide 53 clinically validated targets 53 effector function 53 human antibody therapeutics 53 #ME# 53 Fleximer 53 humanized monoclonal 53 liposome formulations 53 chemical entities NCEs 53 antiviral compounds 53 protein kinase C 53 selectively inhibit 53 epigenetic enzymes 53 PPARg 53 superantigens 53 tumor specific antigen 53 Cyclosert 53 secretory pathway 53 metalloprotease 53 mTOR inhibitors 53 immatics 53 nanobodies 53 DOS# 53 virus AAV 53 nanomolar 53 Zysolin TM 53 M2 subunit 53 ADME properties 53 oral prodrug 53 optimal dosing regimens 53 eIF 4E 53 Anticalin 53 MEK ERK 53 radiolabeled monoclonal antibody 53 PSMA ADC 53 polyclonal antibodies 53 Enkephalin 53 prostanoid 53 XmAb ® 53 Aganocide 53 PEGylated 53 NS5b 53 Clusterin 53 EndoTAG TM -1 53 XL# XL# 53 defensin mimetic antibiotic 53 orally administered inhibitor 53 DNA gyrase 53 NEUGENE antisense 52 phage display libraries 52 Factor Receptor 52 PKM2 52 ESBA# 52 proliferative disorders 52 selective HDAC inhibitors 52 multitargeted 52 New Chemical Entities 52 recombinant protein 52 mGluR2 52 myeloma cells 52 antisense 52 NuMimetic TM 52 glycolipids 52 generation URAT1 inhibitor 52 hybridomas 52 CDK inhibitor 52 TPI ASM8 52 protein quantitation 52 Pathway Inhibitor 52 TTR gene 52 pharmacodynamic biomarkers 52 novel immunomodulatory 52 c Raf kinase 52 Aurora kinase inhibitor 52 FOLOTYN ® 52 Vaccinex 52 CD# ligand 52 therapeutic antibodies 52 Hsp# inhibition 52 UniBody 52 CRTH2 52 IL 7R 52 anticancer therapies 52 NS4B 52 Pertuzumab 52 oncolytic viruses 52 CXCR4 52 PTP 1B 52 HepDirect 52 pRb 52 Poly ICLC 52 microRNA biomarkers 52 HER3 52 interferon IFN 52 Camptothecin 52 ONCONASE R 52 ribonuclease 52 nucleosides 52 gamma secretase inhibitor 52 antisense therapies 52 PDE# 52 prostone 52 microtubule inhibitor 52 EndoTAG 52 mimetic compounds 52 soluble proteins 52 anticancer agent 52 induce apoptosis 52 bispecific antibody 52 immunotoxins 52 aggregated Abeta 52 LentiVector technology 52 #beta HSD 1 52 cMET 52 Antisense 52 HCV protease inhibitor 52 transgenic rats 52 Locked Nucleic Acid 52 rifamycin 52 quinoline 52 AKT1 52 Spiegelmer 52 transfection reagents 52 hypoxia inducible factor 52 ligases 52 CCR1 52 PNP inhibitor 52 epigenetic therapeutics 52 penetrating peptides 52 rBChE 52 efflux pump 52 TKB# 52 pyrimidine 52 vidofludimus 52 glucan 52 T#I [002] 52 MAb 52 anticancer compounds 52 neuronal nicotinic receptors NNRs 52 oncolytic virus 52 PLX# 52 Spiegelmers R 52 IMPDH 52 Bavituximab 52 Affibody ® molecules 52 Sphingomab 52 CCR9 52 liposomal delivery 52 Epstein Barr Virus EBV 52 telomerase inhibitors 52 proteins peptides 52 muscarinic 52 OXIGON TM 52 CCR5 mAb 52 immunogens 52 pDCs 52 bispecific antibodies 52 AVI NEUGENE 52 protein tyrosine phosphatase 52 neuropsychiatric diseases 52 investigational humanized monoclonal antibody 52 PI3K/Akt pathway inhibitor 52 miRNAs 52 nanoparticle formulation 52 plasmid DNA vaccine 52 ketolide antibiotic 52 SMaRT ™ 52 GRNVAC1 52 IGF IR 52 transthyretin TTR 52 FGFR3 52 peptide inhibitors 52 5 HT2A inverse 52 CollaFix TM 52 HCV polymerase inhibitors 52 MIF protein 52 myeloproliferative disorders 52 antisense inhibitor 52 Adnectin 52 nicotinic alpha 7 52 peptide fragments 52 chronic viral infections 52 Angiocept 52 selective androgen receptor modulators 52 IMA# 52 JAK inhibitor 52 NXL# 52 RAV# 52 hemorrhagic fever viruses 52 TMEM#B 52 Lisofylline LSF 52 TRAIL receptor antibodies 52 isotype 52 small molecule 52 small molecule agonists 52 lentiviral 52 Protease inhibitors 52 anti CD# antibody 52 protein ligand 52 CBLC# 52 Xencor XmAb 52 DXL TM 52 anti EGFR antibody 52 sphingolipid 52 secretase 52 Olig2 52 granzyme B 52 HCV antiviral 52 antiangiogenesis therapies 52 apoptotic pathway 52 receptor agonists 52 factor receptor FGFR 52 Cdc7 52 mGluR4 51 nanocarriers 51 HepDirect prodrug 51 intracellularly 51 apoptosis proteins 51 virosome 51 ZFP TF 51 MetAP2 51 ligands 51 PEG SN# 51 peptidic 51 peptide therapeutics 51 missense mutations 51 siderophores 51 novel anticancer 51 bafetinib 51 endostatin 51 mGluR5 antagonist 51 membrane receptors 51 daptomycin 51 antibacterial compounds 51 non nucleoside 51 Aviptadil 51 IGF 1R 51 endoglin 51 stapled peptides 51 methyl D aspartate 51 proprietary PEGylation 51 HuCAL R 51 HAAH 51 viral antigens 51 oral antiviral 51 prolyl hydroxylase inhibitors 51 5 hmC 51 novel anti infective 51 p# activation 51 cytotoxin 51 PARP inhibitor 51 engineered proteases 51 immunomodulators 51 HSP# inhibitor 51 HuCAL 51 Sertoli cell 51 effector functions 51 Scil Proteins 51 Onconase 51 p# subunit 51 Liposomal 51 Cellzome 51 radiolabeled 51 small interfering RNA 51 Immunotherapeutic 51 melanocortin receptor agonists 51 glioblastoma cells 51 ANGPTL4 51 RIP1 kinase 51 susceptibility genes 51 #HT#A 51 telomerase inhibitor 51 naturally occurring antibodies 51 AVP #D# 51 HGS ETR1 mapatumumab 51 Tumor Necrosis Factor 51 anticoagulant reversing agent 51 MOR# 51 CCR5 receptor 51 single stranded oligonucleotides 51 including eniluracil ADH 51 synthetic cannabinoid compounds 51 synthetic analogues 51 recombinant polyclonal antibody 51 picomolar 51 histone methyltransferases HMTs 51 GPR# agonist 51 GMX# 51 vivo validation 51 modulates Akt 51 novel antibody therapeutics 51 Tarvacin 51 Onalta 51 Euroscreen 51 ALN VSP 51 RAF kinase 51 IFNs 51 PRLX # 51 NF KB 51 sirtuin therapeutics 51 Reports Preclinical Data 51 monoclonal antibody therapeutics 51 retroviral vectors 51 EML4 ALK 51 integrase inhibitors 51 Activating mutations 51 ADME Tox 51 polyketide 51 Ceflatonin 51 bacterial enzyme 51 Pentraxin 2 51 IgGs 51 Solazed TM 51 miRNA molecules 51 Macrophage 51 VEGF pathway 51 MAbs targeting 51 neuropilin 51 p# mitogen activated 51 Tranzyme 51 HDAC 51 POTELLIGENT ® 51 HuMax CD# 51 anti secretory 51 kappa opioid receptor 51 nanoparticle formulations 51 maturation inhibitors 51 survivin 51 RECOTHROM R 51 Vegenics 51 stem cell therapeutics 51 binding affinities 51 nanoviricide drug 51 defensins 51 small molecule tyrosine 51 radezolid 51 PORxin 51 cyclin dependent kinase inhibitor 51 Viprovex TM 51 c myb 51 posttranslational modifications 51 IgG1 51 Hypoxia Inducible Factor 51 serine proteases 51 diagnostic biomarkers 51 GPNMB 51 DXL TM antibodies 51 SinuNase ™ 51 ArQule Kinase Inhibitor Platform 51 antisense RNA 51 SGLT2 inhibitors 51 liposomal formulation 51 PPAR gamma 51 GSK3B 51 CD3 monoclonal antibody 51 synthetic peptides 51 heterocyclic 51 MVA BN R 51 cytoprotective 51 Systemic Delivery 51 HER2 ErbB2 51 potent cytotoxic 51 Dapagliflozin 51 HQK 51 T#M 51 bcl 2 51 opioid receptors 51 Novosom 51 ATL# [002] 51 MT#/MEDI-# 51 RenaZorb TM 51 monocytes macrophages 51 ERK pathway 51 JAK2 enzyme 51 glioma cells 51 Monoclonal Antibody 51 RONDEL TM 51 RONDEL ™ 51 anti infective treatments 51 histone deacetylase HDAC inhibitor 51 TNFa 51 inhibit angiogenesis 51 HepDirect R 51 HGS ETR2 51 multiplex assay 51 novel therapeutic antibodies 51 Exelixis compounds 51 fusion inhibitors 51 selective kinase inhibitor 51 AtuRNAi 51 NeoLipid TM 51 KRAS oncogene 51 DNA methylation biomarkers 51 tkRNAi technology 51 taxane derivative 51 theranostic 51 IMiDs 51 Cathepsin S 51 recombinant adeno associated 51 CDDO Im 51 humanized anti 51 trimeric 51 isoform selective 51 metabolite profiling 51 kallikrein 51 plectasin 51 bispecific 51 S#P# 51 Phylomer 51 VIPR2 51 Blinatumomab 51 NPC 1C 51 noncoding RNA 51 NCEs 51 5 HT2A serotonin 51 antisense oligonucleotide 51 CellPort Technologies 51 monoclonal antibody MAb 51 BiTE antibody 51 cancer therapeutics 51 protein tyrosine phosphatase 1B 51 Pentad TM 51 pathophysiological effects 51 antibodies 50 PDGFR 50 LY# [003] 50 pharmacological chaperone 50 busulfan 50 signal transduction inhibitor 50 liposomal formulations 50 Cylene 50 selective antagonist 50 Omacetaxine 50 MUC1 50 MolecularBreeding 50 SGLT inhibitors 50 alpha#beta# integrin 50 CDK inhibitors 50 Monoclonal antibodies 50 NF kB pathway 50 epithelial tissues 50 tyrosine kinase receptor 50 VDAs 50 allosteric modulator 50 RNAi compounds 50 telomerase activators 50 RhuDex ® 50 delipidation 50 targeted antifolate 50 exon skipping 50 Dicer Substrate Technology 50 5 hydroxymethylcytosine 50 vitro assay 50 Wnt signaling pathway 50 fatty acid biosynthesis 50 PDE4 inhibitors 50 tests miRview TM 50 NovaBay Aganocide compounds 50 LJ# [002] 50 CCR5 receptor antagonists 50 Photodynamic therapy PDT 50 acetylcholine receptor 50 alvespimycin 50 ProtAffin 50 auristatin 50 CDK4 50 siRNA molecules 50 anti CD3 antibody 50 mesothelin 50 Nedd4 50 Fleximer R 50 LNA TM 50 IGF1R 50 pharmacokinetic properties 50 ERK1 2 50 targeting PCSK9 50 CD# antibody [001] 50 CD# expressing 50 protein therapeutics 50 therapeutics 50 Tissue Factor 50 aerosolized AAT 50 somatic mutations 50 toxic amyloid beta 50 immunoregulatory 50 photosensitizer 50 dSLIM 50 Scancell 50 Nrf2 pathway 50 Tarvacin Anti Viral 50 ALN TTR# 50 microRNA molecules 50 Personalized Immunotherapy 50 methylation markers 50 novel orally bioavailable 50 stranded LNA 50 phage display technology 50 Abeta peptide 50 deacetylase inhibitors 50 synthetic siRNA 50 prognostic markers 50 Smac mimetic 50 Wnt beta catenin 50 c MYC 50 pyrimidines 50 effector molecules 50 transmembrane proteins 50 Curaxin 50 macrolide antibiotics 50 Gammagard Liquid 50 Nautilus Biotech 50 micro RNA 50 ErbB3 50 anti CD# monoclonal 50 AKIP ™ 50 JAK#/JAK# 50 Zolinza 50 siRNA constructs 50 biotherapeutics 50 mRNA sequences 50 DGAT 50 specific lectin receptors 50 IGFBP2 50 agonistic human 50 plasma proteins 50 Darapladib 50 polymerase inhibitor 50 tumor antigen 50 PI3K 50 Sudhir Agrawal D.Phil 50 TRAIL induced apoptosis 50 Debio 50 Archexin 50 PI3K AKT 50 EGF receptor 50 nonviral 50 MAGE A3 ASCI 50 lysosomal storage diseases 50 MyVax R 50 EGFR pathway 50 ProNAi 50 XmAb ™ 50 interleukin IL -# 50 albumin binding 50 protein antigens 50 AAV vector 50 5 lipoxygenase 50 mammaglobin 50 biotherapeutic 50 TLR9 50 tkRNAi 50 endosomal release 50 drug conjugate 50 siRNA binds 50 PLX cells 50 biomarkers 50 acetylcholinesterase AChE 50 antibody reagents 50 hydrolases 50 intranasal delivery 50 Hepatocellular Carcinoma HCC 50 antifungal compounds 50 synthetic peptide 50 BRAF protein 50 hypermethylated 50 sigma receptors 50 small molecule thrombopoietin 50 fusion protein 50 CYC# 50 DepoVax 50 activate SIRT1

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