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(Click for frequent words.) 71 neuroprotective properties 68 dose dependently 68 antitumor effects 68 mediated inhibition 67 cardioprotective effects 67 hepatic fibrosis 67 antiproliferative effects 67 anti fibrotic 67 redox active 67 flavopiridol 66 immunomodulatory effects 66 antiapoptotic 66 eNOS 66 neuronal dysfunction 66 receptor antagonists 66 microglial activation 66 cardioprotection 66 neuroprotection 66 inhibitory effects 66 prostanoid 66 fatty acid oxidation 66 receptor inhibitor 66 neurotrophic factor 66 paricalcitol 66 LPS induced 66 lipoic acid 66 mGluR2 NAM 66 transgenic mouse models 65 HMG CoA reductase inhibitors 65 ERK signaling 65 lung fibrosis 65 selective inhibition 65 neuroinflammation 65 PPARγ 65 protein tyrosine phosphatase 65 anti amnesic 65 HepG2 cells 65 CCR1 65 superoxide dismutase 65 ERK1 2 65 mimetics 65 antitumor efficacy 65 inhibitory effect 65 anticancer activity 65 neuro protective 65 IL 1ß 65 receptor blocker 65 mGluRs 65 Fas ligand 65 erythropoietic 65 Lipoic acid 65 TNFa 65 TGF beta1 64 receptor antagonism 64 antidepressant efficacy 64 receptor blockers 64 activin 64 vasodilatory 64 #ß 64 antitumor 64 spermidine 64 somatostatin 64 neurotrophic 64 CEACAM1 64 murine model 64 dietary antioxidants 64 LTB4 64 lipoxygenase 64 neurotoxicity 64 PTHrP 64 renal fibrosis 64 TNFalpha 64 muscarinic 64 oxysterols 64 pathophysiological effects 64 CDK inhibitor 64 riociguat 64 pan HDAC inhibitor 64 E selectin 64 activated microglia 64 antiproliferative activity 64 bexarotene 64 remyelination 64 motor neuron degeneration 64 selective modulator 64 antitumor effect 64 dietary supplementation 64 5 HT1A 64 IL 1β 64 PEDF 64 immuno modulatory 64 elastase 64 interleukins 64 neuronal differentiation 63 CTGF 63 M1 muscarinic 63 parthenolide 63 metabolizing enzyme 63 antiangiogenic activity 63 vasodilatation 63 preclinically 63 coenzyme Q# CoQ# 63 vivo potency 63 bioactivity 63 glomerular 63 immunoreactivity 63 p# MAP kinase inhibitor 63 TGF ß 63 coenzyme Q 63 SIRT1 activator 63 CoQ 63 gamma secretase inhibitor 63 phosphatidylserine PS 63 acetyl L carnitine 63 fibrotic disease 63 carnosine 63 NMDA antagonist 63 selective agonist 63 vidofludimus 63 Preclinical studies 63 TNF α 63 arachidonic acid AA 63 potent inhibition 63 demonstrated antitumor activity 63 N acetyl 63 interferon IFN 63 adrenoceptor 63 osteopontin 63 PDGFR 63 plasma pharmacokinetics 63 upregulates 63 cardio protective 63 fosbretabulin 63 isoprostanes 63 cyclophilin D 63 pyridoxal 63 Pharmacokinetic studies 63 myo inositol 63 uricase 63 #beta HSD1 63 hepatotoxic 63 adult neurogenesis 63 Akt activation 63 Kupffer cells 63 Pterostilbene 63 Valproic acid 63 apoE 63 TrkB 63 N acetylcysteine 63 SAMe 63 MMP# 63 CYP#B# 63 clomipramine 63 RRM1 63 transgenic mouse model 63 peroxisomal 63 acetylcholine receptor 63 tryptase 63 p# activation 63 phospholipase 63 pharmacodynamic profile 63 SYN# 63 cholecystokinin CCK 63 VMAT2 63 cytoprotective 63 LT NS# 62 ENMD # 62 Aldosterone 62 mediated apoptosis 62 db db mice 62 IFN β 62 PPAR γ 62 ENaC 62 Alpha lipoic acid 62 SGS# 62 neuropathologic 62 chemopreventive effects 62 chemoprotective 62 UDCA 62 antioxidant supplementation 62 glucocorticoid receptor 62 p#NTR 62 olmesartan 62 mutant huntingtin 62 endogenous ligands 62 liver fibrosis 62 Squalamine 62 pro angiogenic 62 selective antagonist 62 choroidal neovascularization 62 cardiac valvulopathy 62 neuroprotective 62 Vidofludimus 62 sulindac 62 mecamylamine 62 serum biomarkers 62 endothelial nitric oxide 62 dopamine reuptake 62 pharmacokinetic interactions 62 SSc 62 induced apoptosis 62 osteoblast activity 62 antiangiogenic 62 polyamines 62 amyloid deposition 62 atherogenesis 62 γ secretase 62 GRNCM1 62 polyamine 62 vascular inflammation 62 glutamatergic 62 induce apoptosis 62 isoenzymes 62 transgenic rats 62 silibinin 62 receptor subtypes 62 NKG2D 62 antidiabetic 62 ERalpha 62 pleiotropic effects 62 erythropoiesis 62 oncomodulin 62 experimental autoimmune encephalomyelitis 62 alpha7 62 potent inhibitors 62 radiolabeled 62 chemopreventive 62 SERMs 62 peptide CGRP 62 mitochondrial biogenesis 62 thyrotropin 62 #beta 62 induces apoptosis 62 inverse agonist 62 neovascularization 62 neurodegeneration 62 matrix metalloproteases 62 interleukin IL -6 62 macrolide antibiotics 62 atypical neuroleptics 62 biochemical abnormalities 62 mineralocorticoid 62 ACh 62 plasma kallikrein 62 beta 1a 62 leukemia AML 62 GHRH 62 DFMO 62 thrombin receptor 62 bile acid 62 anti angiogenic 62 Overexpression 62 nNOS 62 PC# cells 62 tumor necrosis 62 activate AMPK 62 lysosomal 62 CYT# potent vascular disrupting 62 airway remodeling 62 malate 62 triglyceride lowering 62 alpha lipoic acid 62 peroxidase 62 inosine 62 GSK3B 62 tumorigenicity 62 NK1R 62 neurite outgrowth 62 Symadex 62 nattokinase 62 coenzyme Q# 62 PDE7 inhibitors 62 lymphocyte activation 62 pyrimidines 62 S/GSK# 62 Interferon alpha 62 Protelos R 62 NTx 62 Angiotensin Converting Enzyme 62 immunomodulation 62 histone acetylation 62 endothelial dysfunction 61 IFN γ 61 VEGF receptor 61 HPA axis 61 p# alpha [001] 61 TGF β 61 Elevated serum 61 imatinib resistance 61 leptin deficient 61 serum retinol 61 #β estradiol 61 Posiphen 61 plasma renin activity 61 mitochondrial toxicity 61 GPx 61 cyanocobalamin 61 antiandrogens 61 mRNA expression 61 factor TNF 61 nitric oxide synthase 61 cis retinoic acid 61 c Fos 61 NMDAR 61 OGG1 61 cytokine receptor 61 retinoid X 61 Inosine 61 anti atherogenic 61 PDE1 61 muscarinic receptors 61 calcitonin gene related 61 favorable pharmacokinetic profile 61 chemopreventive agent 61 experimentally induced 61 pomalidomide 61 bronchial epithelium 61 acetylcholinesterase 61 naturally occurring molecule 61 type glutamate receptor 61 N methyl 61 platelet activation 61 TMEM#B 61 hydrolases 61 antitumour 61 azacytidine 61 endothelial nitric oxide synthase 61 immune modulating 61 overactivation 61 #ME# 61 5 HT2C receptor 61 IgG1 61 enzyme cofactor 61 CCR9 61 beta amyloid peptide 61 endotoxemia 61 cyclooxygenase 2 61 mice overexpressing 61 immune modulator 61 HDAC2 61 ALDH2 61 PARP1 61 highly selective inhibitor 61 p# MAPK 61 antisense inhibition 61 neuroregenerative 61 caspase inhibitors 61 HDACi 61 receptor agonists 61 pro apoptotic 61 heme oxygenase 1 61 immunomodulatory 61 CYP #A# 61 experimental allergic encephalomyelitis 61 caspofungin 61 GPR# [002] 61 CaPre ™ 61 extracellular dopamine 61 IL #E 61 reuptake inhibitor 61 alveolar epithelial cells 61 bronchodilatory 61 LRAT 61 Onconase 61 acyl CoA 61 galanin 61 ERK activation 61 HQK 61 malondialdehyde 61 TPMT 61 upregulation 61 serum cortisol 61 ApoA1 61 neuron degeneration 61 miR #a [001] 61 adrenocorticotropic hormone ACTH 61 thalidomide Thalomid 61 lipid synthesis 61 nonsteroidal 61 ellagitannins 61 PSN# [002] 61 hepatocyte growth 61 deferiprone 61 allopregnanolone 61 histone deacetylase inhibitor 61 tiotropium bromide 61 NAGS deficiency 61 Topiramate 61 endoplasmic reticulum stress 61 antisense inhibitor 61 ALB # 61 Enzastaurin 61 ubiquinol 61 mTOR inhibitors 61 idebenone 61 CIMZIA ™ 61 airway hyper responsiveness 61 platelet aggregation 61 prostate cancer CaP 61 citicoline 61 neuro degeneration 61 tetrahydrobiopterin 61 hepatotoxicity 61 excitotoxic 61 interstitial fibrosis 61 PKC beta 61 IL6 61 mitogen activated protein kinase 61 gastric carcinogenesis 61 LPA1 receptor 61 davunetide intranasal AL 61 null mice 61 enzyme inhibitors 61 Preclinical studies suggest 61 resolvin 61 PPAR gamma agonists 61 AST ALT 61 inhibit metastasis 61 autophagic 61 neurological manifestations 61 fatty acid synthase 61 #HT#A 61 nicotinamide 61 solithromycin 61 neuronal degeneration 61 Abeta# 61 β amyloid 61 mGlu2 3 61 61 ADAMTS# 61 Fenretinide 61 TG# [003] 61 Lactobacillus reuteri 61 BMP2 61 prostaglandin D2 61 ß carotene 61 Prodarsan ® 61 myeloproliferative diseases 61 proteasome inhibitor 61 Parkinson disease PD 61 dose proportionality 61 ganciclovir 61 vivo validation 61 Monocyte 61 neurotrophic factors 61 berberine 61 airway hyperresponsiveness 61 induced oxidative stress 61 Estradiol 61 serotonin receptor 61 antisense oligonucleotide 61 triglyceride concentrations 61 mdx mouse 61 mGluR5 antagonist 61 quinoline 61 natriuretic 61 estrone 61 nicotinic receptor 61 trans resveratrol 61 Angiotensin converting enzyme 60 CBLC# 60 dexpramipexole 60 selectively inhibits 60 TGF ß1 60 Hcy 60 MAPK pathway 60 DXL# 60 proteolysis 60 metabolic dysfunction 60 LSI #P 60 cobalamin 60 urothelium 60 cysteamine 60 parathyroid hormone PTH 60 GH secretion 60 IFN beta 60 serotonin synthesis 60 glutathione peroxidase 60 GSTM1 60 resolvins 60 beta adrenergic 60 CaPre TM 60 ionophore 60 Pgp 60 D aspartic acid 60 enzyme cytochrome 60 aminotransferase 60 prostaglandin synthesis 60 MPTP 60 isoenzyme 60 cytochrome P 60 inhibit platelet aggregation 60 relapsed MM 60 microsomal 60 CB2 receptor 60 depsipeptide 60 prostate cancer PCa 60 glutamate receptors 60 monohydrate 60 NMDA receptor antagonists 60 semisynthetic 60 tHcy 60 Oxidative damage 60 glucose homeostasis 60 antioxidative 60 histone deacetylase inhibitors 60 PD LID 60 SLC#A# [002] 60 agonist induced 60 serine protease 60 estrogen receptor beta 60 antiarrhythmic 60 immunostaining 60 Afatinib 60 Tyrima 60 motilin 60 endocannabinoid signaling 60 beta sitosterol 60 VA# [002] 60 pulmonary toxicity 60 ubiquinone 60 cytokine IL 60 N acetylcysteine NAC 60 Apoptone 60 calcitriol 60 5 HT1A receptor 60 prolyl 60 mitochondrial function 60 proteoglycan 60 tumor regressions 60 β2 60 ß1 60 Angiotensin 60 adenosine receptors 60 Th1 type 60 oxidative metabolism 60 amyloid plaque formation 60 gastrointestinal stromal tumors GISTs 60 cannabinoid receptor 60 superoxide dismutase SOD 60 serum concentrations 60 androgen dependent 60 hippocampal neurogenesis 60 proteolytic enzyme 60 SCD1 60 ob ob mice 60 OHR/AVR# 60 PlGF 60 PHD2 60 agonism 60 protein tyrosine phosphatase 1B 60 CG# [003] 60 Co enzyme Q# 60 vascular disrupting agents 60 xenograft models 60 axonal damage 60 dopamine transporter 60 lymphocyte proliferation 60 allergic inflammation 60 CLA supplementation 60 preclinical efficacy 60 potentiation 60 podocytes 60 gamma aminobutyric acid 60 opioid antagonists 60 NF kappaB activation 60 PKC inhibitor 60 Aß 60 hydroxylase 60 cyclooxygenase 60 beta carotene supplementation 60 reductase 60 visilizumab 60 synaptogenesis 60 cefotaxime 60 plasma lipid 60 cardiac repolarization 60 mu opioid receptor antagonist 60 pharmacodynamic properties 60 rHuEPO 60 parkinsonism 60 lymphocyte counts 60 Natalizumab 60 peroxisome proliferator activated 60 protein kinase C 60 metreleptin 60 Immunohistochemical analysis 60 anticancer agent 60 equol 60 downregulated 60 Glypromate 60 hypoxia inducible factor 60 STX# 60 Upregulation 60 cardiotoxic 60 MMP2 60 colorectal adenoma 60 4E BP1 60 antiinflammatory 60 gene polymorphism 60 colorectal carcinogenesis 60 tyrosine phosphorylation 60 antitumoral 60 ibudilast 60 uPA 60 ADAGIO study 60 acetyltransferase 60 mu opioid 60 epithelial sodium 60 ectopic expression 60 osteoblast 60 SR# [004] 60 metastatic malignant 60 iron chelators 60 thromboxane A2 60 peptide hormone 60 partial agonist 60 receptor subtype 60 β blockers 60 PI3K Akt 60 TAT2 60 CD#c 60 monocyte chemotactic protein 60 lenalidomide dexamethasone 60 inhibit enzymes 60 antioxidant enzyme 60 aminobutyric acid 60 silymarin 60 Htt 60 beta amyloid peptides 60 edifoligide 60 CGEN # 60 genotoxicity 60 noscapine 60 amyloid peptide 60 cMET 60 axonal degeneration 60 bone metabolism 60 AT1R 60 triacylglycerol 60 lymphoid cells 60 urate oxidase 60 nAChR 60 PPAR gamma agonist 60 NRG1 60 pressure natriuresis 60 NMDA antagonists 60 somatostatin analog 60 enzyme inhibitor 60 Notch1 60 neuroprotectant 60 FasL 60 Raf MEK ERK 60 adipogenic 60 serine threonine 60 anti inflammatory cytokine 60 pDCs 60 Jurkat cells 60 serum triglycerides 60 HuLuc# 60 neurofibrillary 60 pharmacokinetic characteristics 60 Teriflunomide 60 HIF PHIs 60 L lysine 60 EGFR HER2 60 Janus kinase 60 enzyme inhibition 60 extrapyramidal symptoms 60 recombinant erythropoietin 60 endogenous glucose 60 tartrate 60 UCP2 60 infliximab Remicade 60 BMP signaling 60 cell adhesion molecule 60 chemokine receptor 60 cardiac myocytes 60 growth hormone secretion 60 blood clotting protein 60 N acetyl cysteine 60 sensitizer 60 IL 1beta 60 bFGF 60 vaso occlusive crisis 60 glucagon receptor 60 c MYC 60 pomegranate extract 60 DITPA 60 nondemented 60 Clusterin 60 myeloperoxidase 60 CagA 60 immunomodulatory properties 60 urate lowering 60 CDDO Im 60 COX enzymes 60 insulin sensitizers 60 pDC 60 pathogenic mechanisms 60 prostate carcinoma 60 developmental neurotoxicity 60 intestinal absorption 60 kallikrein 60 cyclin dependent kinase inhibitor 60 potent vasodilator 60 vWF 60 prostaglandin E1 60 PGC 1α 60 PsA 60 rBChE 60 chitinase 60 anti proliferative 60 glutamyl 60 analgesic effects 60 inducible nitric oxide synthase 60 osteogenic differentiation 60 Aâ 60 HIF 1α 60 enkephalin 60 nicotinic acetylcholine receptor 60 degranulation 60 MELAS 60 tau pathology 60 apolipoprotein 60 receptor gamma 60 trodusquemine 60 ABCA1 60 cynomolgus monkeys 60 JAK inhibitors 60 sitosterol 60 noradrenergic 60 serum cholesterol 60 MAO B 60 genetically altered mouse 60 luteolin 60 metabolomic profiles 60 superoxide anion 60 antifibrotic 60 PKCi 60 lymphotoxin 60 selective adenosine 60 partial agonists 59 HSP# inhibitor 59 tea polyphenols 59 trastuzumab Herceptin ® 59 neprilysin 59 AKT inhibitor 59 highly selective endothelin 59 hydrolase 59 K ras mutations 59 intracellular accumulation 59 pituitary hormone 59 osteocalcin 59 lesional 59 selectively binds 59 neurokinin 1 59 tocopherol 59 serotonin transporter 59 imexon 59 pro inflammatory cytokine 59 MTHFR 59 adenosine A2A receptor 59 phosphatidylinositol 3 59 PTP 1B 59 radiosensitivity 59 oligomerization 59 leukotriene B4 59 hyperalgesia 59 vivo 59 dopamine D1 59 oxcarbazepine 59 prolactin elevation 59 liver histology 59 FGFR1 59 alkaline phosphatase ALP 59 prucalopride 59 Granulocyte Colony Stimulating Factor 59 coenzyme 59 anti androgen 59 tubulin polymerization 59 memantine Namenda 59 Nicotinic acid 59 EP1 receptor 59 S#A# [002] 59 miRs 59 Subgroup analysis 59 bronchoalveolar 59 p# mitogen activated 59 rolipram 59 conventional DMARDs 59 Homocysteine 59 interleukin IL -# 59 constitutively expressed 59 enterolactone 59 antitumour activity 59 exendin 4 59 polycythemia vera PV 59 potent anticancer 59 MMP7 59 transthyretin 59 plasminogen activator 59 coadministration 59 LNCaP cells 59 potent inhibitor 59 resistant mutants 59 curcuminoids 59 malondialdehyde MDA 59 urocortin 59 5 HT2A 59 transcriptional regulation 59 HIF PHI 59 Angiolix 59 neovascular 59 miglustat 59 hypericin 59 oxidative stress markers 59 Valdoxan 59 Nicotinamide 59 intact parathyroid hormone 59 vivo efficacy 59 pegylated liposomal doxorubicin 59 CRF antagonists 59 monogenic 59 TRAIL induced apoptosis 59 endostatin 59 anticonvulsants 59 prostate epithelial cells 59 thymosin beta 4 59 bleomycin 59 IKK2 59 xanthine 59 systemically administered 59 MGd 59 IMP# 59 PON1 gene 59 COX2 59 SIRT1 activation 59 aurora kinase 59 retinoid 59 p#INK#a 59 sulphonylureas 59 glucocorticoid 59 benfotiamine 59 Angiotensin II 59 PEGPH# 59 estrogen metabolism 59 amyloid β 59 transgene expression 59 insulin sensitizing 59 viral titers 59 eicosanoids 59 LRP5 59 neuronal nitric oxide synthase 59 renoprotective 59 ABCB1 59 mineralocorticoid receptor 59 ERK pathway 59 5alpha reductase 59 sulfasalazine 59 V#F mutation 59 phosphate S1P 59 5HT 59 physico chemical properties 59 pharmacokinetics PK 59 cannabinor 59 epigallocatechin gallate EGCG 59 BACE1 59 urothelial cancer 59 NMDA receptor antagonist 59 neurosteroid 59 anti inflammatory cytokines 59 LHRH agonists 59 cystic fibrosis transmembrane conductance 59 NPD1 59 mitochondrial respiration 59 alpha glucosidase 59 costimulation 59 cyclin E 59 Darapladib 59 Hepatotoxicity 59 Dasatinib 59 5 hydroxytryptamine 59 Mg Uk 59 NS#/#A protease 59 pharmacokinetic parameters 59 HDL2 59 vitro cytotoxicity 59 annexin 59 adrenal function 59 palmitoleate 59 potently inhibits 59 MP4OX 59 prodrugs 59 pentoxifylline 59 forskolin 59 P2X 59 thermosensitive 59 catabolism 59 potently inhibited 59 gonadotrophin releasing hormone GnRH 59 aripiprazole Abilify 59 Anticalins ® 59 IFN α 59 NADPH oxidase 59 astrocytic 59 metaplasia 59 ZD# [001] 59 dopaminergic neurons 59 metabolic parameters 59 brivaracetam 59 treat benign prostatic 59 Lp PLA 2 59 beta Estradiol 59 nicotinic acid 59 N Acetyl 59 mice genetically altered 59 t# c# CLA 59 monocytic 59 osteogenic 59 anti androgens 59 tumor hypoxia 59 polymerase inhibitor 59 colorectal carcinoma 59 TNF receptors 59 phosphorylated tau 59 lupus anticoagulant 59 promoter polymorphism 59 phytoestrogen 59 tocotrienols 59 adrenomedullin 59 beta lactamases 59 systemic inflammation 59 cediranib 59 urinary excretion 59 Wnts 59 tipifarnib 59 NKT cells 59 TLR4 59 heterozygotes 59 cytotoxicity 59 monoamine oxidase inhibitors 59 autoantigens 59 splenocytes 59 GSK3 59 Pharmacodynamics 59 mitochondrial enzyme 59 effector function 59 cAMP signaling 59 Sirtuin 59 enzymatic activity 59 trabedersen 59 cognitive dysfunction 59 hepatoma 59 JAK3 59 GliSODin 59 substrate specificity 59 Superoxide 59 acadesine 59 collagen degradation 59 mTOR mammalian target 59 clioquinol 59 mutant huntingtin protein 59 neurogenic 59 Safinamide 59 zileuton 59 hyperinsulinemia 59 paraneoplastic 59 Epidemiologic studies 59 eicosanoid 59 soluble fms 59 Xanafide 59 mucins 59 Celecoxib 59 GSTT1 59 SRT# [003] 59 oxidase 59 anti CD3 59 PTPN# 59 neurotransmitters serotonin 59 sCD# 59 bile acid metabolism 59 kinase inhibition 59 Amino acid 59 alagebrium 59 glycogen synthase kinase 59 TTR gene 59 peroxidation 59 serotonin uptake 59 cardiac toxicity 59 pharmacologically active 59 myocyte 59 SIRT2 59 probiotic supplementation 59 dioxygenase 59 PI3K/mTOR 59 melatonin receptor 59 nicotinic acetylcholine receptors 59 WNK1