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(Click for frequent words.) 79 neurons 78 neural 76 neuron 76 synaptic 75 axonal 73 neurones 72 nerve cells 72 cortical 70 hippocampal 69 dopaminergic neurons 68 hippocampal neurons 68 neuronal cell 67 neural circuits 67 BDNF 67 dopamine neurons 67 neurogenesis 66 cytoskeletal 66 synapses 66 inhibitory 66 interneurons 65 neuronal dysfunction 65 glial 65 synaptic plasticity 65 striatal 65 anterior cingulate 65 synaptogenesis 65 neuronal cells 65 neurodegeneration 65 synapse formation 65 basal ganglia 65 Wnt signaling 65 motor neuron 64 axons 64 visual cortex 64 neuronal activity 64 neuronal plasticity 64 intracellular signaling 64 dopamine signaling 64 hypothalamic 64 endothelial 64 neurochemical 64 neurone 64 granule cells 64 myelination 64 BMP signaling 64 glutamate receptors 64 NMDA receptors 63 retinal ganglion cells 63 neuronal differentiation 63 excitatory 63 cortical neurons 63 dendritic spines 63 glutamate 63 inhibitory interneurons 63 neurotransmitter 63 midbrain 63 synaptic transmission 63 neuronal degeneration 63 astrocyte 63 transcriptional regulation 63 GABAergic interneurons 63 Purkinje cells 63 dopaminergic 63 glutamatergic 63 synapse 63 presynaptic 62 calpain 62 tau protein 62 astrocytes 62 hippocampus 62 signaling pathways 62 phenotype 62 cerebellar 62 intracellular 62 Aβ 62 neuronal function 62 dentate gyrus 62 serotonergic 62 neurite outgrowth 62 NKT cell 62 AMPA receptors 62 autophagic 62 pyramidal neurons 62 synaptic function 62 neural cells 62 postsynaptic 62 MEF2 61 neuronal circuits 61 gene expression 61 plasticity 61 cortex 61 neuromuscular junction 61 neuroendocrine 61 Neuronal 61 glial cell 61 axon 61 sensory neurons 61 ERK1 2 61 endothelial cell 61 mitochondrial 61 adult neurogenesis 61 proteins 61 astrocytic 61 motor neurons 61 protein synthesis 61 striatum 61 MAP kinase 61 neuronal synapses 60 molecular mechanisms 60 apoptotic 60 alpha synuclein 60 myelin 60 cholinergic 60 neuronal migration 60 actin cytoskeleton 60 vascular endothelial cells 60 transcription factors 60 TGF b 60 DISC1 60 skeletal muscle 60 induced neuronal 60 cerebellum 60 HPA axis 60 proteolysis 60 demyelination 60 neuropeptides 60 kinase pathway 60 hindbrain 60 retinal neurons 60 nociceptive 60 NMDA receptor 60 glia 60 neuronal circuitry 60 posterior cingulate cortex 60 brain circuitry 60 oligodendrocyte 60 MAPK 60 tumorigenesis 60 phenotypes 60 Wnt 60 Purkinje cell 60 mPFC 60 catenin 60 cAMP signaling 60 FOXO 60 isoforms 59 vivo 59 dopaminergic neuron 59 endogenous 59 Notch signaling 59 histone 59 SIRT3 59 extracellular 59 GABAergic neurons 59 β catenin 59 microglial 59 dendrite 59 amyloid β 59 Smad3 59 synaptic proteins 59 myogenesis 59 neuronal connections 59 cAMP 59 phosphorylation 59 mutant protein 59 dorsolateral 59 renal fibrosis 59 mRNAs 59 genotoxic stress 59 mRNA 59 dendritic spine 59 endoplasmic reticulum 59 Notch1 59 overactivation 59 mitochondrial respiration 59 mTOR signaling 59 neural crest 59 Wnt pathway 59 F actin 59 serotonin signaling 59 brain 59 somatosensory cortex 59 beta catenin 59 modulatory 59 SIRT1 59 inducible 59 molecular mechanisms underlying 59 chromatin structure 59 cardiac myocytes 59 leptin signaling 59 podocytes 59 excitatory synapses 59 signaling pathway 59 TGF β 59 glutamatergic neurons 59 excitotoxic 59 NR2B 59 molecular mechanism 59 dopamine 59 sensorimotor 58 ubiquitination 58 caveolin 1 58 remyelination 58 paxillin 58 prefrontal cortical 58 neurotransmitter receptors 58 melanocyte 58 nerve fibers 58 retinal cells 58 histone acetylation 58 mutant SOD1 58 excitotoxicity 58 chromatin remodeling 58 E cadherin 58 neural circuitry 58 lysosomal 58 primary visual cortex 58 superior colliculus 58 GluR1 58 Aß 58 neuronal signaling 58 ACh 58 progranulin 58 circadian clock genes 58 HSF1 58 ERK pathway 58 protein kinase C 58 mRNA expression 58 signaling molecule 58 hippocampal cells 58 mitogen activated protein kinase 58 IL 1β 58 exocytosis 58 Htt 58 dystroglycan 58 mammalian brain 58 subcortical 58 calcium homeostasis 58 autophagy 58 POMC neurons 58 focal adhesions 58 molecular pathway 58 neurites 58 AMPA receptor 58 ubiquitin ligase 58 cypin 58 forebrain 58 afferent 58 p# protein 58 cytokine 58 SVZ 58 p# activation 58 habenula 58 cingulate 58 Ca2 + 58 genomic instability 58 hypocretin neurons 58 inhibitory neurons 58 glial cells 58 dendritic 58 connexin# 58 neurotransmission 58 huntingtin 58 MAPK pathway 58 microglia 58 corticospinal 58 neural mechanisms 58 GABAergic 58 BMP4 58 limbic 58 Wnt proteins 58 Neurons 58 overexpression 58 motoneurons 58 neural plasticity 58 neurophysiological 58 neurobiological 58 neurotransmitter glutamate 58 dendrites 58 p# pathway 58 knockout mice 58 thalamic 58 tumor suppressor protein 58 fatty acid oxidation 58 ATPase 58 molecular pathways 58 SIRT1 gene 58 protein kinase 58 Rab5 58 nNOS 58 transgenic mouse model 58 acetylcholine 58 evolutionarily conserved 57 entorhinal cortex 57 nAChR 57 intestinal epithelium 57 centrosome 57 cell motility 57 term potentiation 57 rhodopsin 57 MDSCs 57 osteoblast 57 apoE 57 biogenesis 57 dysregulation 57 Dysregulation 57 TrkB 57 Cdc# 57 brainstem 57 serotonin transporter 57 medial prefrontal cortex 57 β cells 57 hsp# 57 amygdala 57 epithelial cell 57 morphogen 57 overexpressing 57 IL 1beta 57 NR2B subunit 57 intracellular calcium 57 cyclin E 57 neurotrophic factors 57 cilium 57 neuroligin 57 S#A# [002] 57 alternative splicing 57 PIP2 57 rostral 57 catecholamine 57 pathophysiological 57 spermatogenesis 57 neural crest cells 57 NAc 57 CaM kinase II 57 PTPN# 57 hypothalamic pituitary adrenal axis 57 mutant huntingtin protein 57 H#K# [002] 57 serotonin receptor 57 p# MAPK 57 cellular senescence 57 ABCA1 57 Skp2 57 electrophysiological 57 transcriptional 57 subcellular 57 serotonin 57 afferents 57 podocyte 57 insulin receptors 57 cohesin 57 homeostatic 57 monocyte 57 membrane protein 57 ENaC 57 hepatic stellate cells 57 cytosol 57 Foxp3 57 myocyte 57 adhesion molecule 57 mesolimbic 57 GABAA receptors 57 mammalian 57 mitochondrial proteins 57 HOTAIR 57 excitatory neurons 57 hyperactivation 57 chromosome condensation 57 Rac1 57 estrogen receptor alpha 57 dopamine receptors 57 mitotic 57 GABA neurotransmitter 57 mirror neuron system 57 mutant mice 57 inhibition 57 signaling molecules 57 agonist induced 57 neuroanatomical 57 perirhinal cortex 57 factor BDNF 57 synapse maturation 57 PKMzeta 57 E3 ubiquitin ligase 57 neurite 57 acetylcholine receptors 57 metabolic enzymes 57 transcriptional activation 57 secretory cells 57 ubiquitylation 57 ectopic expression 57 intercellular communication 57 physiological 57 caveolin 57 cellular organelles 57 phagocytosis 56 axon guidance 56 cognition 56 BMAL1 56 metabolic 56 reactive oxygen species 56 p#Kip# 56 neuroligins 56 C. elegans 56 epigenetic alterations 56 intron 56 regulated kinase ERK 56 insulin secreting cells 56 oxidative stress 56 transcriptional repressor 56 caspase activation 56 cellular pathways 56 biological pathways 56 BDNF gene 56 receptor gamma 56 alpha synuclein protein 56 lipid metabolism 56 physiologic 56 D2 receptor 56 neurofilament 56 Pten 56 striatal neurons 56 MEF2D 56 Prox1 56 pyramidal cells 56 TNFR 56 c Myc 56 cardiomyocyte 56 photoreceptor cell 56 synaptic vesicles 56 transgene expression 56 cell adhesion 56 premotor 56 ERK signaling 56 lateral hypothalamus 56 extracellular signal 56 ion channels 56 proinflammatory 56 photoreceptor 56 TGF beta 56 p# [001] 56 ChR2 56 stromal cells 56 mutant proteins 56 calmodulin 56 protein tau 56 neurotransmitters 56 Nrf2 56 retinal photoreceptors 56 upregulation 56 CTGF 56 Jhdm2a 56 TGF ß 56 autocrine 56 Hh pathway 56 cyclins 56 eNOS 56 neural pathways 56 dopamine transporter 56 Sgk1 56 axonal damage 56 gene 56 PrP 56 hedgehog signaling 56 hepatocyte 56 Id1 56 CEACAM1 56 tumor suppressor gene 56 neurofibrillary tangles 56 BACE1 56 biochemical 56 calcineurin 56 noradrenergic 56 MyoD 56 myocardial tissue 56 immunological 56 TGF beta pathway 56 RhoA 56 cardiac fibroblasts 56 IKKß 56 Akt 56 retinal ganglion cell 56 noncoding RNAs 56 ß catenin 56 nitric oxide synthase 56 SOCS3 56 neurotransmitter dopamine 56 neuronal pathways 56 posterior cingulate 56 mesoderm 56 heterochromatic 56 mitochondrial dysfunction 56 myelin sheath 56 receptors 56 sensory neuron 56 LDL receptor 56 polyamines 56 c myc 56 cell signaling pathways 56 epithelial 56 myocardial 56 LKB1 56 Wnt1 56 TGFβ 56 gliosis 56 mutant huntingtin 56 striatal dopamine 56 OPHN1 56 cytosolic 56 transcriptional regulators 56 epigenetic regulation 56 epigenetic 56 motor neuron degeneration 56 tyrosine phosphorylation 56 antioxidant enzyme 56 LIS1 56 glomerular 56 adhesion molecules 56 TLR4 56 neuroinflammatory 56 glycosylation 56 tumor suppressor genes 56 oligodendrocytes 56 ErbB4 56 molecular chaperones 56 dopamine neuron 56 palytoxin 56 orexin neurons 56 transgenic mice expressing 56 β cell 56 metabolic pathways 56 Rap1 56 cortico 56 UCP2 56 inflammatory cytokine 56 mutated protein 56 amygdala neurons 56 serotonergic neurons 56 signaling cascades 56 biochemical pathway 56 synaptic connections 56 efferent 56 peroxisome 56 molecular 56 anterior temporal lobe 56 glutamate receptor 56 neurotrophin 56 cortical regions 56 hippocampal function 56 miRNAs 56 tyrosine 56 signal transduction 56 NADPH oxidase 55 myocytes 55 paracrine 55 neural pathway 55 MT1 MMP 55 Hh 55 GAPDH 55 thalamus 55 TGF ß1 55 chloroplast 55 mammalian cells 55 brain plasticity 55 Hox gene 55 serotonin neurons 55 β amyloid 55 telomeric 55 DNMT1 55 MAPKs 55 catabolism 55 D2 receptors 55 hyperexcitability 55 CaMKII 55 beta1 integrin 55 mitochondria 55 PC# cells 55 axonal degeneration 55 non coding RNA 55 neuroblasts 55 macrophage 55 hematopoiesis 55 pDCs 55 spectrin 55 chondrocyte 55 atherogenesis 55 FasL 55 EZH2 55 protein 55 plasma membrane 55 c MYC 55 locus coeruleus 55 embryogenesis 55 MeCP2 55 vagal 55 ciliary 55 organogenesis 55 neuronal stem cells 55 receptor subtypes 55 neural stem cells 55 cholesterol metabolism 55 cognitive deficits 55 presenilin 55 trophic factors 55 rostral anterior cingulate cortex 55 TAp# 55 proto oncogene 55 midbrain dopamine neurons 55 prefrontal 55 TNFalpha 55 dorsolateral prefrontal cortex 55 enzymatic activity 55 NF kB 55 activin 55 neuroprotection 55 FGF# 55 plasminogen 55 neuroepithelial cells 55 DARPP 55 miR# 55 tau 55 Androgen receptor 55 LXRs 55 glucocorticoid receptors 55 autoregulation 55 osteoclast 55 homodimers 55 STAT3 55 microglial cells 55 neuropathological 55 secretory 55 epigenetic silencing 55 cortical plasticity 55 costimulatory 55 progerin 55 cytokinesis 55 nociceptors 55 ERK2 55 glutamate signaling 55 neural tissue 55 apoptosis 55 methylation 55 Kv#.# 55 phosphorylated 55 amyloid beta 55 mRNA translation 55 transcriptional regulator 55 apoptotic pathway 55 DNA methylation 55 gene p# 55 RANKL 55 gene transcription 55 axonal transport 55 HSCs 55 amyloid protein 55 dysregulated 55 Abeta 55 estrogen receptor 55 leptin receptors 55 biochemical pathways 55 PPAR γ 55 RGCs 55 caudate 55 PON1 55 beta globin 55 glucose metabolism 55 induced apoptosis 55 cadherin 55 CD1d 55 neural substrates 55 basal forebrain 55 glucocorticoid 55 Sonic hedgehog 55 sortilin 55 actin 55 hypothalamus 55 ß amyloid 55 stathmin 55 leptin 55 neurotrophic factor 55 subventricular zone 55 miR 55 hippocampal formation 55 acetylcholine neurotransmitter 55 histone modification 55 gene encoding 55 cyclic AMP 55 morphogenesis 55 nicotinic receptors 55 Schwann cells 55 myofibroblasts 55 tumor suppressor 55 Aâ 55 apoptotic cell 55 transmembrane 55 glucocorticoid receptor 55 mirror neuron 55 sensory axons 55 insulin secretion 55 photoreceptors 55 GPR# receptor [002] 55 mTORC1 55 focal adhesion 55 melanocortin receptors 55 neurosteroid 55 sphingolipid 55 myosin II 55 γδ T cells 55 MyD# 55 FGF signaling 55 downregulate 55 neurodegenerative diseases 55 MMP2 55 PPAR gamma 55 kinase domain 55 matrix metalloproteinases 55 radial glia 55 neurosteroids 55 FGF2 55 polyglutamine 55 epigenetic mechanisms 55 IFN γ 55 netrin 1 55 palmitoylation 55 Mcl 1 54 fronto 54 MAP kinases 54 SOD1 54 basolateral 54 MAP kinase pathway 54 EGFR signaling 54 P cadherin 54 ontogeny 54 phenotypic 54 Shh signaling 54 acetylation 54 morphogens 54 c Myb 54 neuropeptide Y 54 serine threonine kinase 54 microRNAs 54 nucleosome 54 cognitive 54 Abeta protein 54 transthyretin 54 neurotrophins 54 monoamine 54 secretory pathway 54 IKK2 54 NKG2D 54 3'UTR 54 Clusterin 54 cognitive functions 54 DNA methylation patterns 54 gyrus 54 Lhx2 54 micro RNAs 54 oligomerization 54 airway remodeling 54 exon 54 microglial activation 54 neuregulin 54 RNA polymerase II 54 brain derived neurotrophic 54 TRPV1 receptors 54 dorsal horn 54 vimentin 54 huntingtin protein 54 acetylcholine receptor 54 FMRP 54 genes encoding 54 DLC1 54 signaling cascade 54 TORC2 54 neuronal apoptosis 54 Fig. 1C 54 posterior parietal 54 axon regeneration 54 locomotor activity 54 RNA polymerases 54 pRb 54 GRP# 54 transgenic mice 54 thymocyte 54 cilia 54 BMP receptor 54 ventral prefrontal cortex 54 endoplasmic reticulum ER 54 adherens junctions 54 endonuclease 54 IGF2 54 Hox genes 54 tau phosphorylation 54 oscillatory 54 CHD7 54 iNOS 54 Golgi apparatus 54 aldosterone 54 protein phosphorylation 54 Sonic Hedgehog 54 lymphocyte 54 retinal pigment epithelium 54 thioredoxin 54 HSP# 54 microRNAs miRNAs 54 Hedgehog signaling 54 cytokines 54 protein misfolding 54 toxic beta amyloid 54 subgenual cingulate 54 amino acid 54 circadian genes 54 SH2 B 54 auxin 54 receptor 54 oxidative phosphorylation 54 Brain derived neurotrophic 54 synuclein 54 proinflammatory cytokines 54 stem cell differentiation 54 mTOR 54 tissue homeostasis 54 neurotransmitter receptor 54 contractile 54 neural tissues 54 hemichannels 54 fibroblasts 54 senescent cells 54 chromosomal regions 54 primary cilia 54 ventromedial 54 miR #a [001] 54 neural connections 54 mitochondrial function 54 T lymphocyte 54 vacuolar 54 oncomodulin 54 coding RNA 54 neurofibromin 54 apoE4 54 p# mutations 54 HIF 1a 54 H#K#me# 54 mutant SOD1 protein 54 Fc receptor 54 temporal lobe 54 Treg cells 54 medial temporal 54 NAD + 54 NF κB 54 cerebral cortex 54 transcriptional repression 54 dephosphorylation 54 transmembrane receptor 54 PGE2 54 caveolae 54 isoform 54 PU.1 54 SUMOylation 54 paralogs 54 miRNA expression 54 activated microglia 54 angiogenesis 54 neocortical 54 TRPA1 54 axonal regeneration 54 TRPV4 54 VE cadherin 54 acinar 54 gamma secretase 54 arcuate nucleus 54 oncoprotein 54 Notch signaling pathway 54 deficient mice 54 epithelia 54 ncRNAs 54 MALAT1 54 Cdk5 54 amyloid deposition 54 arginase 54 regulate gene expression 54 NPD1 54 glutamate transporters 54 vmPFC 54 cellular metabolism 54 induces apoptosis 54 inosine 54 miR #a [002] 54 cyclin 54 Notch pathway 54 ventromedial prefrontal cortex 54 endocannabinoid system 54 lymphoid cells 54 palladin 54 RUNX3 54 chromatin 54 humoral 54 glucose transporter 54 dynamin 54 p#INK#a 54 HDAC6 54 proteases 54 myogenic 54 hypermethylation 54 innate immune 54 c Src 54 endoplasmic reticulum stress 54 temporoparietal junction 54 intracellular proteins 54 tubulin 54 PDGFR 54 prefrontal cortex 54 paraventricular nucleus 54 somatic 54 epithelial tissues 54 cytochrome c 54 NFAT 54 inflammatory cytokines 54 X inactivation 54 calcium ion 54 photoreceptor cells 54 osteoclast formation 54 Mitochondrial 54 cyclooxygenase 2 54 chromatin remodeling complex 54 neurturin 54 hedgehog pathway 54 neuropeptide 54 apoptosis programmed cell 54 intronic 54 PINK1 54 nerve axons 54 XBP1 54 proteoglycan 54 PGC 1α 54 ncRNA 54 Cdx2 54 endogenous stem cells 54 p# Shc 54 TRPV3 54 IGFBP2 54 RNA splicing 54 CD#L 54 PI3K 54 centromere 54 Hsp# [001] 54 GLUT4 54 telomerase activity 54 suppressor gene 54 phosphorylated tau 54 caspase 54 cofilin 54 PTEN protein 54 p# gene 54 cortices 54 FoxO1 54 posterior parietal cortex 54 microtubule 54 amygdala reactivity 54 IL 1ß 54 neurofibrillary 54 mechanotransduction 54 neutrophil 53 amyloid deposits 53 histone modifications 53 monocytes 53 DNA demethylation 53 chemokine 53 amyloid proteins 53 synaptic vesicle 53 Sirt1 53 mitochondrial biogenesis 53 meiotic 53 CA3 53 beta endorphin 53 JAK2 53 polyamine 53 downregulation 53 somatosensory 53 erythropoiesis 53 mediated phosphorylation 53 serine protease 53 sirtuin 53 E#F# 53 GnRH neurons 53 NF kappaB 53 transcriptional coactivator 53 PIP3 53 beta globin gene 53 cellular signaling pathways 53 hippocampal neurogenesis 53 deacetylation 53 medial frontal cortex 53 CTCF 53 STAT1 53 integrin 53 frontal parietal 53 inhibitory synapses 53 angular gyrus