neurodevelopment

Related by string. Neurodevelopment * * neurodevelopment disorders . fetal neurodevelopment . neurodevelopment disorder *

Related by context. All words. (Click for frequent words.) 71 neurodevelopmental 68 neurobehavioral 66 neurodevelopmental outcomes 66 prenatal exposure 65 neuro developmental 64 prenatal exposures 64 utero exposure 63 neurodevelopmental outcome 63 thyroid hormone levels 63 reproductive abnormalities 63 thyroid hormones 63 neurodevelopmental disorders 62 neuromotor 62 phthalate exposure 62 thyroid function 62 cognitive deficits 62 carbohydrate metabolism 61 developmental abnormalities 61 synaptic function 61 neuroendocrine 61 bone metabolism 61 fetuses infants 61 Prenatal exposure 61 hypothalamic pituitary adrenal axis 60 FMRP protein 60 neurotoxic effects 60 cholesterol metabolism 60 IUGR 60 neurocognitive 60 pubertal 60 psychosocial functioning 60 epigenetic changes 60 reproductive hormones 59 onset puberty 59 brain neurochemistry 59 mitochondrial dysfunction 59 antenatal depression 59 Maternal obesity 59 hormone secretion 59 Secondhand smoke exposure 59 Genetic predisposition 59 ovarian hormones 59 cognitive function 59 cognitive 59 cognitive functioning 58 attention-deficit/hyperactivity disorder ADHD 58 endocrine disruption 58 hippocampal function 58 Stress hormones 58 impair cognitive 58 adrenal function 58 metabolic abnormalities 58 adult neurogenesis 58 hyperactivity inattention 58 adiposity 58 neuropsychiatric disorders 58 glucocorticoid hormones 58 calcium homeostasis 58 lipid metabolism 58 orofacial clefts 58 genital defects 58 bronchopulmonary dysplasia 58 airway reactivity 58 cognition 58 HPA axis 58 obesity insulin resistance 57 placental function 57 fatty acid oxidation 57 endocrine 57 neurocognitive deficits 57 hyperinsulinemia 57 environmental toxicants 57 Magnesium deficiency 57 maturational 57 insulin resistance 57 dysregulation 57 penile erection 57 pubertal maturation 57 teratogens 57 folate deficiency 56 ERK signaling 56 thyroid dysfunction 56 intestinal microflora 56 genital abnormalities 56 gastrointestinal dysfunction 56 neurodevelopmental disorder 56 endocrine disrupting chemicals 56 prepubertal 56 prefrontal cortical 56 inhibitory neurotransmitters 56 persistent pulmonary hypertension 56 psychomotor 56 estrogen metabolism 56 serotonin signaling 56 Thyroid hormone 56 neural plasticity 56 STAT3 signaling 56 glucose metabolism 56 neurological impairments 56 medium chain acyl 56 serotonin neurotransmitter 56 fetal malformations 56 airway responsiveness 56 hormone imbalances 56 male hormone androgen 56 neonatal encephalopathy 56 neurological abnormalities 56 metabolic abnormality 56 neuronal dysfunction 56 neuropsychological functioning 56 neurochemistry 56 endocrine dysfunction 56 glucose homeostasis 55 neuropsychological deficits 55 thyroid hormone deficiency 55 airway remodeling 55 synapse formation 55 cognitive dysfunction 55 neurobehavioural 55 preterm deliveries 55 atopic disease 55 Oxidative stress 55 Schoppe Sullivan 55 reproductive endocrine 55 synapse maturation 55 synaptic plasticity 55 dietary interventions 55 postnatally 55 menstrual irregularity 55 Rh incompatibility 55 synaptogenesis 55 impaired cognition 55 proinflammatory 55 Thyroid hormones 55 Irva Hertz Picciotto 55 Folic acid deficiency 55 growth hormone secretion 55 prostate carcinogenesis 55 inherited mutations 55 menarche 55 sleep deprivation impairs 55 structural abnormalities 55 attention-deficit/hyperactivity disorder 55 allergic sensitization 55 alexithymia 55 developmental delays 55 lipoprotein metabolism 55 callous unemotional traits 55 neurotransmission 55 hippocampal volume 55 pituitary hormone 55 neuronal differentiation 55 plasma lipids 55 organophosphate exposure 55 Nutritional deficiencies 55 CNTNAP2 55 metabolic acidosis 55 neuronal plasticity 55 mitochondrial oxidative 55 systemic inflammation 55 intestinal motility 55 mimics estrogen 55 precocious puberty 54 organochlorine compounds 54 folate metabolism 54 subclinical atherosclerosis 54 Hyperactivity 54 cardio metabolic 54 atherogenesis 54 estrogenic effects 54 genomic imprinting 54 ingestive behavior 54 pAkt 54 neurotransmitters serotonin 54 PON1 54 organophosphate pesticides 54 carcinogenesis 54 elevated cortisol 54 hormonal abnormalities 54 neurological impairment 54 Genetic variants 54 DHA supplementation 54 p# activation 54 nitric oxide synthase 54 neonatal morbidity 54 adiponectin levels 54 synaptic transmission 54 hypoxia ischemia 54 daytime alertness 54 behavioral disinhibition 54 cAMP signaling 54 cognitive affective 54 fetal neurodevelopment 54 neuropsychiatric diseases 54 neurofibromin 54 neuroligins 54 mitochondrial mutations 54 birthweight 54 hormone cortisol 54 causal pathways 54 dietary DHA 54 untreated ADHD 54 neurosensory 54 adrenal cortex 54 hyperbilirubinemia 54 platelet activation 54 colorectal carcinogenesis 54 antioxidant supplementation 54 Socioeconomic status 54 IGF1 54 neurodevelopment disorder 54 immunological mechanisms 54 metabolic dysfunction 54 neurotransmitter norepinephrine 54 autism spectrum disorders ASD 54 micronutrient intake 54 acetylcholine neurotransmitter 54 NMDA receptors 54 neurotrophins 54 neurological 54 mcg dl 54 neurosteroid 54 serum cholesterol 54 plasma lipid 54 docosahexaenoic acid 54 potentially modifiable 54 perinatal outcomes 54 verbal apraxia 54 epigenetic alterations 54 cognitive stimulation 54 cortical plasticity 54 p# mutations 54 congenital adrenal hyperplasia CAH 54 spermatogenesis 54 HGPS 54 perceptual reasoning 54 GABAergic interneurons 54 polyhydramnios 54 attentional 54 FeNO 54 phthalate metabolites 54 phthalate syndrome 53 Andrew Wyrobek 53 elevated homocysteine 53 prenatal testosterone 53 G6PD deficiency 53 severe hyperbilirubinemia 53 developmental disorders 53 immunotoxicity 53 endocrine disrupter 53 MCADD 53 neurotrophic 53 onset diabetes mellitus 53 Soy isoflavones 53 comorbid disorders 53 dysregulated 53 mental retardation epilepsy 53 pharmacologic treatments 53 endocrine disrupters 53 recurrent miscarriage 53 neuroinflammation 53 T1DM 53 neuroinflammatory 53 carotid atherosclerosis 53 low birthweight 53 vascular reactivity 53 calcium absorption 53 shorter telomere length 53 body fatness 53 mitochondrial function 53 malignant transformation 53 developmental neurotoxicity 53 dietary calcium 53 serotonergic 53 endocrine hormone 53 immunological 53 SIRT1 protein 53 M. vaccae 53 endothelial function 53 de novo mutations 53 neurodevelopmental disability 53 folate intake 53 neuro developmental disorders 53 Apert syndrome 53 cataract formation 53 nerve degeneration 53 neurotransmitter serotonin 53 insulin secretion 53 neurotoxicity 53 neurotransmitters dopamine 53 vascular dysfunction 53 recurrent abdominal pain 53 pathophysiological 53 Familial hypercholesterolemia 53 depressive symptomatology 53 primary ovarian insufficiency 53 hyperactivity 53 physiologic 53 dietary antioxidants 53 thyroid hormone 53 amyloid beta plaque 53 SRBD 53 undescended testicles 53 airway hyperresponsiveness 53 teratogenic 53 neuropathological 53 metabolic 53 unmeasured factors 53 impaired endothelial 53 behavioral disturbances 53 Elevated serum 53 biochemical abnormalities 53 amyloid peptide 53 untreated celiac disease 53 congenital toxoplasmosis 53 Decety 53 neuronal signaling 53 cognitive functions 53 oral clefts 53 PM#.# exposure 53 steroid hormones 53 motor neuron degeneration 53 serum IGF 53 mild cognitive 53 Hormonal changes 53 prothrombotic 53 excitatory synapses 53 asthma rhinitis 53 autonomic dysfunction 53 PPAR γ 53 chromosomal anomaly 53 Calcium intake 53 Vitamin D insufficiency 53 BLLs 53 hormones leptin 53 inattention hyperactivity 53 Hertz Picciotto 53 Repeated concussions 53 neurocognition 53 congenital malformations 53 serotonin synthesis 53 hormone disrupting 53 elevated serum ALT 53 serum BDNF 53 #ß HSD1 53 male reproductive tract 53 perinatal complications 53 insulin signaling pathways 53 antiphospholipid antibodies 53 hormones neurotransmitters 53 microglial 53 iron supplementation 53 gallstone formation 53 podocytes 53 behavioral abnormalities 53 mitochondrial metabolism 53 nongenetic 53 leptin receptor 53 alpha amylase 53 endothelial dysfunction 53 telomere maintenance 53 neurocognitive functioning 53 allergic inflammation 53 neural tube defects NTDs 53 cerebellar 52 mental retardation syndromes 52 Genetic variation 52 beta endorphin 52 CNTNAP2 gene 52 circulating estrogens 52 LIS1 52 serum parathyroid hormone 52 myo inositol 52 neurobiological 52 oncomodulin 52 term potentiation LTP 52 genetic susceptibility 52 prostaglandin E2 52 endocrine disruptors 52 fatty acid metabolism 52 pulmonary hypoplasia 52 inadequate calcium intake 52 congenital anomalies 52 #q# deletion syndrome 52 sensorimotor 52 sonographic diagnosis 52 brainstem serotonin 52 chronic periodontitis 52 neurohormone 52 serum lipids 52 POMC neurons 52 physiological 52 Glucocorticoids 52 neurogenesis 52 aetiological 52 PDGFR 52 lymphangiogenesis 52 cardiorespiratory fitness 52 neurohormonal 52 excitotoxic 52 FGF2 52 lymphocyte activation 52 endocrine disrupting 52 coronary artery atherosclerosis 52 cardio respiratory fitness 52 KIBRA 52 Notch signaling 52 mutant huntingtin protein 52 developmental trajectories 52 probiotic supplementation 52 telomere length 52 hypothalamic pituitary axis 52 UVB induced 52 hormonal milieu 52 Breastfed infants 52 parietal cortices 52 Wnt signaling 52 clefting 52 adrenal suppression 52 thyrotropin 52 p#INK#a 52 dietary intakes 52 premorbid 52 intermittent exotropia 52 polycystic ovary syndrome PCOS 52 nongenetic factors 52 female hormones estrogen 52 researchers hypothesised 52 epilepsy cerebral palsy 52 activate AMPK 52 gastric carcinoma 52 pathophysiological mechanisms 52 externalizing behaviors 52 chromosomal instability 52 cognitive abilities 52 APOE genotype 52 Neurogenesis 52 STAT4 52 sleep disturbances 52 predisposing factor 52 reproductive toxicity 52 Choline 52 myelination 52 hematological abnormalities 52 Prolactin 52 Iron deficiency 52 hormone IGF 52 synaptic dysfunction 52 Estrogen deficiency 52 insulin sensitivity 52 prefrontal cortex PFC 52 monoamine 52 congenital hypothyroidism 52 dopamine signaling 52 pre eclamptic 52 estrogen receptor alpha 52 D2 receptor 52 neurocognitive function 52 UCP2 52 CYP#B# 52 endogenous opioids 52 ACh 52 autistic traits 52 subclinical hypothyroidism 52 prenatal phthalate exposure 52 gut microbiota 52 internalizing disorders 52 skeletal abnormalities 52 hypopituitarism 52 hedgehog signaling 52 GH deficiency 52 heterozygous familial 52 neuronal degeneration 52 Smad3 52 BCL#A 52 malformations 52 glutamate receptors 52 craniofacial anomalies 52 dopamine receptor gene 52 neurocircuitry 52 adrenocortical 52 neuronal migration 52 Essential fatty acids 52 arachidonic acid AA 52 neuropsychiatric disorder 52 stress hormone corticosterone 52 recurrent wheezing 52 hypothalamic pituitary 52 placental 52 Neural tube defects 52 Chronic sleep deprivation 52 NF1 52 Alzheimer pathology 52 oxidative stress 52 lipid homeostasis 52 hypocretin 52 dietary folate 52 Hypothalamic 52 Th1 cells 52 preterm infant 52 VLBW 52 autophagic 52 impairs cognitive 52 allergen induced 52 Depressive symptoms 52 genetic susceptibilities 52 neural tube defect 52 humoral immunity 52 renal fibrosis 52 brain neurotransmitter 52 Chronic insomnia 52 creatine supplementation 52 intra uterine 52 neurodevelopmental impairment 52 chromosomal disorder 52 Sleep disordered breathing 51 guinea pigs lubiprostone 51 hypothalamic pituitary adrenal HPA 51 Neurodevelopmental 51 maladaptive behaviors 51 extrapyramidal symptoms 51 Angiotensin converting enzyme 51 facial clefts 51 mtDNA mutations 51 Dysregulation 51 cortical thinning 51 hypoxic ischemic brain 51 hippocampal neurogenesis 51 docosahexaenoic acid DHA 51 caveolin 51 apoE 51 axon outgrowth 51 IKK2 51 axon regeneration 51 neurodegeneration 51 dietary supplementation 51 socioemotional 51 PGD PGS 51 Oxidative damage 51 confounder 51 peroxynitrite 51 phyto oestrogens 51 coinfection 51 exposed prenatally 51 Radiographic findings 51 Endothelial function 51 tumorigenesis 51 bile acid metabolism 51 comorbid anxiety 51 intelligence quotient IQ 51 neuroimaging studies 51 circadian disruption 51 mitochondrial toxicity 51 psychosocial variables 51 serotonergic neurons 51 glucose intolerance 51 antioxidant enzyme 51 tryptase 51 prenatally exposed 51 Developmental Disorders 51 PBDE exposure 51 utero 51 EBV infection 51 cortical excitability 51 mimic estrogen 51 cardiac malformations 51 habitual snoring 51 adverse perinatal 51 epigenetic silencing 51 retinoid X 51 polycystic ovary syndrome 51 serotonin 51 Klinefelter syndrome 51 lipid levels 51 adrenocorticotropic hormone ACTH 51 Hh pathway 51 necrotizing enterocolitis 51 Rubinstein Taybi syndrome 51 sFlt 1 51 hypothalamic 51 Angelman syndrome 51 sodium valproate 51 middle ear effusion 51 Adequate vitamin D 51 irregular menstrual cycles 51 51 underlying pathophysiology 51 dopamine D2 receptors 51 atopy 51 neurodevelopmental disabilities 51 unmeasured confounders 51 overactivated 51 androgen depletion 51 extracellular dopamine 51 NR#A# 51 comorbid depression 51 depressive symptoms 51 MECP2 gene 51 somatic symptoms 51 physiological mechanisms 51 Sjögren syndrome 51 neuropeptide Y NPY 51 spastic diplegia 51 mitochondrial enzyme 51 juvenile idiopathic arthritis 51 amino acid homocysteine 51 Erb palsy 51 hyperactivation 51 fatty acid supplementation 51 serotonin transporter gene 51 middle frontal gyrus 51 affective psychoses 51 ASDs 51 selenium deficiency 51 oxidized LDL 51 inflammatory markers 51 serum homocysteine 51 disorder ASD 51 muscarinic receptors 51 corticotrophin releasing hormone 51 irregular menstrual periods 51 arterial stiffness 51 bronchopulmonary dysplasia BPD 51 autoregulation 51 cryptorchidism 51 autism spectrum disorders 51 inhaled allergens 51 Preterm babies 51 tic disorders 51 mitochondrial fusion 51 Genistein 51 renal scarring 51 serum estradiol 51 circadian clock genes 51 enterocolitis 51 atopic diseases 51 factor BDNF 51 periodontal infection 51 placental insufficiency 51 amenorrhea 51 neurogenerative diseases 51 synaptic proteins 51 syndrome FAS 51 severe Primary IGFD 51 TGF ß 51 insulin resistance syndrome 51 parkinsonism 51 leptin signaling 51 brain derived neurotrophic 51 serotonin deficiency 51 MYCN amplification 51 urinary excretion 51 adenotonsillectomy 51 nulliparous 51 p# MAPK 51 atopic eczema 51 HRQOL 51 hormone secreted 51 amblyopic 51 LPS induced 51 Th1 type 51 lethargy irritability 51 salivary cortisol 51 Singh Manoux 51 CB2 receptor 51 physiological arousal 51 lipid profiles 51 Personality traits 51 neurotransmitter GABA 51 Iron deficiency anemia 51 oestrogenic 51 hypocalcaemia 51 fasting insulin 51 prefrontal regions 51 preterm infants 51 NRF2 gene 51 podocyte 51 endogenous opioid 51 prolactin 51 hyperactivated 51 metabolic alterations 51 organogenesis 51 intercellular communication 51 heterotaxy 51 biologic pathways 51 RBP4 51 Frontal lobe 51 infertility miscarriages 51 tic severity 51 chromosomal alterations 51 NOD2 51 genistein 51 Fatty acids 51 hyperstimulation 51 dietary fatty acids 51 breastfed infants 51 cAMP pathway 51 excitatory neurotransmitter 51 AMPK activation 51 macrophage migration 51 myelomeningocele 51 juvenile idiopathic arthritis JIA 51 HUCB cells 51 catecholamine 51 noradrenergic 51 pleiotropic effects 51 adaptive immunity 51 hormone aldosterone 51 glucose tolerance 51 hormones secreted 51 cerebral palsy blindness 51 Postpartum depression 51 antitumor efficacy 51 abstinent alcoholics 51 hormone prolactin 51 pathogenetic 51 Reye syndrome rare 51 chromosomal disorders 51 intraventricular hemorrhage 51 neurexins 50 prolactin levels 50 HDAC2 50 protein tau 50 Brain derived neurotrophic 50 #q#.# deletion syndrome 50 underactive 50 hormone angiotensin II 50 iodine intake 50 preeclamptic women 50 dietary acrylamide 50 neuromotor delays 50 serotonin transporter 50 obstetric complications 50 Prolla 50 estrone 50 VEGF expression 50 thermoregulatory 50 paraneoplastic 50 impulsivity 50 RIP1 50 Dietary restriction 50 unhealthy dietary habits 50 endocrine abnormalities 50 tremors numbness 50 gestational diabetes mellitus GDM 50 ADAMTS# 50 inherited metabolic disorders 50 CYP#C# [002] 50 progranulin 50 post natally 50 fluoxetine Prozac 50 modifiable risk 50 amyloid plaque formation 50 Van Cauter 50 urocortin 50 intrauterine 50 shortened telomeres 50 postmenopausal breast cancer 50 temporoparietal 50 leptin deficient 50 endotoxemia 50 metabolic disorders 50 TSLP 50 macrovascular complications 50 brain lesions 50 masculinization 50 kainate 50 residual confounding 50 hydrops 50 dietary nitrate 50 perceptual abilities 50 Neumark Sztainer 50 antioxidant nutrients 50 hormone disruptor 50 disregulation 50 gestational diabetes mellitus 50 pthalates 50 preterm newborns 50 dysglycemia 50 airway hyper responsiveness 50 FASPS 50 Six3 50 signaling cascades 50 diabetic microvascular complications 50 chromosomal aberrations 50 adulthood Fuentes Afflick 50 oxidases 50 Methylmercury 50 puerperal psychosis 50 receptor inhibitor 50 hyperprolactinemia 50 prematurity ROP 50 insulin resistance precursor 50 Alzheimer disease pathology 50 mitochondrial disorders 50 Wernicke Korsakoff syndrome 50 CREB protein 50 Cognitive impairment 50 cardiac conduction 50 endocannabinoid system 50 cholesterol homeostasis 50 Homocysteine 50 psychomotor skills 50 FGFs 50 genotoxicity 50 E selectin 50 metabolic disturbances 50 neurosteroids 50 hepatocellular 50 Inhibitory 50 Down syndrome chromosomal disorder 50 vitamin D inadequacy 50 Endocrine disruptors 50 aneuploidy 50 oncogenesis 50 gastrointestinal motility 50 excitotoxicity 50 CYP #A# 50 adrenal hormones 50 endocrine glands 50 cardiac hypertrophy 50 maternal fetal 50 bone marrow suppression 50 cognitive impairment 50 Notch pathway 50 autism spectrum disorders ASDs 50 improves insulin sensitivity 50 intestinal permeability 50 pituitary hormones 50 COX enzymes 50 biologic plausibility 50 growth restriction IUGR 50 deformational plagiocephaly 50 2A receptor 50 innate immune responses 50 cognitive dysfunctions 50 subcortical structures 50 DNA methylation patterns 50 Fortified foods 50 amino acid metabolism 50 auditory processing 50 impair fertility 50 causal pathway 50 dietary calcium intake 50 handgrip strength 50 seizures comas 50 hemoglobinopathies 50 respiratory illnesses birth defects 50 gastric carcinogenesis 50 vasodilatation 50 masculinizing 50 NKT cell 50 adiponectin 50 calcium supplementation 50 born preterm 50 TNFalpha 50 affective disorders 50 Marc Weisskopf 50 Severe Primary IGFD 50 predisposing factors 50 mRNA expression 50 activated microglia 50 fibrotic disease 50 MAOA 50 eNOS 50 carbohydrate cravings 50 hyperoxia 50 disorders FASD 50 highly heritable 50 intracellular signal transduction 50 psychosocial dwarfism 50 glucocorticoid receptors 50 innate immune 50 FMR1 50 familial clustering 50 TGF β 50 basal ganglia 50 histone deacetylases 50 intestinal inflammation 50 gastrointestinal disturbances 50 LRP5 50 polyamines 50 oxidative stress markers 50 Factor XIII 50 impaired insulin secretion 50 antiphospholipid syndrome 50 protein kinase C 50 Mitochondrial diseases 50 modifiable lifestyle 50 histone methylation 50 hormonal 50 fetal microchimerism 50 Mild hypothermia 50 incretins 50 painful menstrual periods 50 HRQL 50 galanin 50 neuroligin 50 activin 50 GABA gamma aminobutyric acid 50 pharmacokinetic interaction 50 glucocorticoids 50 pharmacological therapies 50 Leukotrienes 50 congenital CMV 50 endocrine diseases 50 placental abnormalities 50 neuropsychological 50 physiologic mechanisms 50 holoprosencephaly 50 adiponectin hormone 50 Alzheimer Disease AD 50 cortisol secretion 50 elastase 50 endocrine disrupting chemicals EDCs 50 perfluorooctanoate PFOA 50 micronutrient supplementation 50 Thiamine 50 mental retardation cerebral palsy 50 dysbindin 50 MCAD deficiency 50 chromosomal anomalies 50 analgesic effects 50 serum folate 50 perimenopausal women 50 MAO B 50 psychobiological 50 β amyloid 50 mutant huntingtin 50 valproate 50 steroidogenic 50 cervical secretions 50 osteomalacia 50 Flavanols 50 hypercoagulability 50 oestrogens 50 compensatory mechanisms 50 triiodothyronine 50 Adiponectin 50 periodontal diseases 50 Sociodemographic 50 chorioamnionitis 50 Cotinine 50 Abeta protein 50 carbohydrate intolerance 50 anterior cingulate gyrus 50 Chronic ITP 50 airway constriction 50 ADAM# 50 Leydig cell 50 antidepressive 50 Disrupted sleep 50 epileptogenic 50 striatal dopamine 50 congenital disorders 50 mucosal immune 50 BMI percentiles 50 thrombophilia 50 dietary nitrite 50 stimulant medications 50 dysfunctional voiding 50 behavioral interventions 50 serotonin receptor 50 methylation patterns 50 innate immunity 50 OPHN1 50 incretin 50 cardiometabolic risk 50 DHA fatty acid 50 Wnt signaling pathway 50 chemical serotonin 50 vitamin B# deficiency 50 ELBW 50 Neuropsychological 50 beta1 integrin 50 genotoxic stress 49 hyperinsulinism 49 #q# deletion 49 MeHg 49 folic acid supplementation 49 apoE4 49 APOE ε4 49 placenta praevia 49 immunodeficiencies 49 heritable disorders 49 dietary intake 49 autism dyslexia 49 PDE#A 49 perfluorooctane sulfonate PFOS 49 PTEN protein 49 prolactin elevation 49 overactivity 49 folate folic acid 49 allergic eczema 49 vascular endothelial 49 interleukins 49 cochlear implantation 49 endogenous hormones 49 pathophysiologic

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