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(Click for frequent words.) 78 signaling pathway 77 molecular pathways 76 Wnt pathway 76 molecular mechanism 75 signaling pathways 73 Notch signaling 72 synapse formation 72 cell signaling pathway 72 Notch pathway 72 cell signaling pathways 72 hedgehog pathway 72 biochemical pathway 71 tumorigenesis 71 signaling cascade 71 tumor suppressor gene 71 biochemical mechanisms 71 tumor suppressor protein 71 STAT3 71 beta catenin 70 epigenetic mechanisms 70 Wnt signaling 70 MAPK 70 SIRT1 70 biochemical pathways 70 cellular pathways 70 mTOR 69 XBP1 69 molecular mechanisms 69 signaling molecule 69 TGF beta pathway 69 Akt 69 tumor suppressor genes 69 Wnt signaling pathway 69 androgen receptor 68 PPAR alpha 68 calpain 68 protein kinases 68 p# pathway 68 FGFR1 68 NF kB 68 SIRT1 gene 68 tumor suppressor 68 receptor protein 68 protein kinase 67 cellular metabolism 67 EGFR signaling 67 Skp2 67 PPAR gamma 67 TGF beta 67 metabolic enzymes 67 FOXO3a 67 PDE5A 67 Wnt 67 histone modifications 67 micro RNAs 67 Akt3 67 protein kinase C 67 LKB1 67 SGK1 67 transcription factors 67 DISC1 67 microRNAs 67 biological pathways 67 Wnt proteins 67 GSK3 67 chromatin structure 66 SOCS1 66 intracellular proteins 66 EZH2 66 Kv#.# 66 NMDA receptor 66 MAPK pathway 66 pRb 66 Wnts 66 glutamate receptors 66 Myc 66 ion channels 66 transcription factor 66 PKM2 66 mutant protein 66 cyclins 66 MAP kinase pathway 66 histone deacetylases 66 NF kappaB 66 NF kappa B 66 GATA3 66 BMP4 66 CaM kinase II 66 NF κB 66 Src 66 RNA splicing 66 Smad3 66 mTOR pathway 66 protein misfolding 66 breast cancer metastasis 66 Hedgehog signaling 66 receptor molecule 66 Six3 66 SIRT3 66 MAP kinase 66 regulates gene expression 66 signal transduction pathways 66 proteins 66 ubiquitination 66 tumor microenvironment 66 microRNA molecules 65 S1P 65 p# gene 65 JAK STAT 65 cholesterol metabolism 65 neuronal migration 65 IGF 1R 65 primary cilia 65 Cdk5 65 SOD1 65 sortilin 65 biochemical cascade 65 HOTAIR 65 FoxO1 65 Jagged1 65 signaling cascades 65 Smoothened 65 glutamate receptor 65 receptor gamma 65 peroxisome proliferator activated 65 neuroligin 65 NF kB pathway 65 proto oncogene 65 tumor angiogenesis 65 Nrf2 65 tyrosine kinases 65 LRP6 65 intracellular signaling 65 TGF b 65 serotonin receptor 65 calcineurin 65 synaptic transmission 65 TGF β 65 oncogene 65 Notch signaling pathway 65 C EBP alpha 65 protein fragment 65 LRP1 65 mitochondrial dysfunction 65 FGFs 65 transcriptional activation 65 apoptotic pathway 65 cellular senescence 65 RUNX3 65 PPAR γ 65 myogenesis 65 TORC2 65 acetylation 65 chromatin remodeling 65 c Abl 65 lipid metabolism 64 oncogenesis 64 Cdc# 64 activin 64 caspases 64 podocyte 64 Ago2 64 PAK1 64 epigenetic alterations 64 AMPA receptors 64 HDACs 64 SH#B# 64 regulated kinase ERK 64 fatty acid synthase 64 c Myc 64 metabolic pathway 64 Stat5 64 MEF2 64 ubiquitin ligase 64 signaling molecules 64 PPARg 64 PPARγ 64 oncoprotein 64 enzyme 64 receptor 64 GRP# 64 uPAR 64 TGF ß 64 gene expression 64 PI3K pathway 64 cytoskeletal 64 RANKL 64 cellular signaling pathways 64 beta arrestin 64 PI3 kinase 64 protein synthesis 64 fatty acid metabolism 64 NR2B 64 axon guidance 64 neurite outgrowth 64 cell motility 64 retinoblastoma protein 64 mitogen activated protein kinase 64 PGE2 64 neurexin 64 MicroRNA 64 cyclin D1 64 molecular signaling pathway 64 p#/CBP 64 IKKa 64 FOXO1 64 Mcl 1 64 FGF# 64 ERK1 2 64 IL 1β 64 neuronal plasticity 64 kinase 64 mTORC1 64 neurotransmitter glutamate 64 Sox9 64 PIP3 64 TSLP 64 integrins 64 retinoic acid 64 PI3K 64 LIS1 64 proNGF 64 insulin secreting cells 64 apoE 64 Sonic hedgehog 64 metabolic processes 63 SH2 B 63 PPAR delta 63 S#K# 63 membrane fusion 63 BMP signaling 63 PKC alpha 63 molecular underpinnings 63 nAChR 63 NFkB 63 intracellular signaling pathways 63 Pax6 63 adhesion molecule 63 physiological mechanisms 63 KLF# 63 KLF4 63 oncogenes 63 hormone leptin 63 costimulatory 63 Rab# 63 autophagy 63 ERK pathway 63 tyrosine phosphorylation 63 palmitoylation 63 bacterial enzyme 63 protein tau 63 LRRK2 63 Pten 63 PAR1 63 p# activation 63 FGFR3 63 FANCD2 63 cAMP signaling 63 secretory pathway 63 actin remodeling 63 miRNAs 63 cathepsins 63 E3 ligase 63 catenin 63 gene p# 63 molecular mechanisms underlying 63 MECP2 63 kinase pathway 63 calmodulin 63 NKT cell 63 Htt 63 actin cytoskeleton 63 nicotinic receptors 63 SCD1 63 overactivation 63 gluconeogenesis 63 synaptic plasticity 63 Hedgehog pathway 63 BCL6 63 epigenetic regulation 63 phosphorylation 63 MeCP2 63 neural mechanisms 63 PGC 1alpha 63 PI3K Akt 63 NFκB 63 membrane protein 63 pathogenic mechanisms 63 genes 63 cytokine 63 Cyclin D1 63 glucocorticoid receptor 63 proteolysis 63 gamma secretase 63 cyclin dependent kinases 63 sumoylation 63 transcriptional regulation 63 Id1 63 RNA molecule 63 microRNAs miRNAs 63 insulin receptors 63 epigenetically 63 CPEB 63 demethylase 63 ion channel 63 overexpression 63 TAp# 63 transcriptional machinery 63 serine threonine kinase 63 Robo4 63 endocannabinoids 63 NFAT 63 NKT cells 63 Frizzled 63 PGC1 63 MDM2 63 SIRT6 63 TFIIH 63 hedgehog signaling 63 biologic pathways 63 NRG1 63 Mdm2 63 PMR1 63 podocytes 63 protein p# 63 progerin 63 gene transcription 63 p# [001] 63 AMPK 63 tyrosine kinase 63 PGC 1α 62 Smurf1 62 neuronal differentiation 62 metabolic pathways 62 PIP2 62 micro RNA 62 lipid synthesis 62 arginase 62 CIB1 62 ACE2 62 carcinogenesis 62 telomerase enzyme 62 ubiquitylation 62 stem cell differentiation 62 Akt1 62 Stat3 62 Hh 62 TXNIP 62 hypermethylation 62 intracellular pathways 62 ß catenin 62 Oct4 62 eNOS 62 Hox gene 62 synaptogenesis 62 Sir2 62 plasma kallikrein 62 estrogen receptor alpha 62 IGFBP2 62 PRDM# 62 Sox# 62 genomic instability 62 neuronal degeneration 62 NMDA receptors 62 VEGF receptor 62 Notch1 62 CXCR2 62 regulating gene expression 62 underlying molecular mechanisms 62 neuromuscular junction 62 ARF1 62 Hypoxia Inducible Factor 62 HGPS 62 microRNA miR 62 aldose reductase 62 casein kinase 62 biochemical processes 62 estrogen receptor 62 p# MAPK 62 Methylation 62 Shh signaling 62 transgenic mouse model 62 CTGF 62 calcium homeostasis 62 secreted protein 62 5 hydroxymethylcytosine 62 transcriptional repressor 62 aromatase 62 protein interleukin 62 Sox2 62 CTLA 4 62 caveolin 1 62 oncomodulin 62 melanocyte 62 nNOS 62 Pin1 62 proteases 62 huntingtin protein 62 FGF2 62 MEK ERK 62 tRNA synthetase 62 apoE4 62 beta1 integrin 62 neurofibromin 62 TGF Beta 62 orexin 62 SIRT2 62 neuropeptide Y NPY 62 chaperone protein 62 huntingtin 62 E cadherin 62 mitogen activated protein 62 mitochondrial fusion 62 tumor suppressors 62 gene expression patterns 62 ADAM# 62 DNA methylation 62 encodes protein 62 kinases 62 macrophage activation 62 Sonic Hedgehog 62 oxidative phosphorylation 62 neuronal function 62 Wnt1 62 DNA methylation patterns 62 GPR# [002] 62 fibroblast growth 62 TORC1 62 glutamate signaling 62 UCP2 62 HCV replication 62 Bcr Abl 62 phosphatases 62 EGF receptor 62 Alu RNA 62 GluR1 62 IRS1 62 DLX5 62 messenger molecule 62 sphingolipid 62 neurotrophin 62 IRF5 62 miR# 62 sirtuin 61 AMPA receptor 61 p# protein 61 synaptic function 61 LDL receptor 61 kalirin 61 chemokine receptor 61 heparan sulfate 61 microglial activation 61 phosphatidylinositol 3 61 Chk1 61 EGFR pathway 61 PTEN protein 61 alpha synuclein gene 61 molecule 61 receptors 61 SATB1 61 PTEN gene 61 transthyretin 61 NKX2 61 E#F# 61 nitric oxide synthase 61 Rev erb 61 OCT4 61 endocannabinoid system 61 histone modification 61 pro angiogenic 61 CPT1c 61 Runx2 61 CCR3 61 cystic fibrosis transmembrane conductance 61 telomere maintenance 61 factor BDNF 61 naturally occurring molecule 61 PI3K AKT 61 EphA2 61 causative genes 61 neurotransmitter receptor 61 MC4R 61 RNA polymerase II 61 neural cells 61 Wnt#b 61 neurotransmitter GABA 61 JAK2 61 lincRNAs 61 fatty acid synthesis 61 PTP1B 61 cannabinoid receptors 61 Apoptosis 61 oncogenic signaling 61 oncogenic 61 osteoclasts 61 hypoxia inducible factor 61 ABCA1 61 glucocorticoid receptor GR 61 integrin 61 Rac1 61 kinase domain 61 estrogen receptors 61 alpha synuclein 61 tumor suppressor p# 61 Sirt1 61 miRNA 61 OPHN1 61 epigenetic changes 61 Th# cells 61 tyrosine kinase receptors 61 BCR ABL 61 mammary cells 61 c MET 61 thrombospondin 61 inflammasome 61 eotaxin 61 neural crest 61 mRNAs 61 enzyme telomerase 61 NF kappaB pathway 61 excitotoxicity 61 E1A 61 semaphorin 61 noncoding RNA 61 noncoding RNAs 61 tumor suppressing 61 neurogenesis 61 CK2 61 nicotinic receptor 61 progranulin 61 adult neurogenesis 61 Wnt beta catenin 61 c MYC 61 Rad# 61 BCL6 gene 61 myeloid cells 61 serotonin signaling 61 RANK ligand 61 organelle 61 airway remodeling 61 histone methylation 61 synapse maturation 61 polyamines 61 mutated protein 61 adenosine receptors 61 nAChRs 61 ATF2 61 Ets2 61 fusion protein 61 TRPV1 61 c myc 61 clusterin 61 IRAK1 61 TGF beta signaling 61 chromosomal instability 61 DARPP 61 autophagic 61 Argonaute 61 COX enzymes 61 USP# 61 Ras pathway 61 cofilin 61 FGF signaling 61 PDGFR 61 E3 ubiquitin ligase 61 beta adrenergic receptors 61 lipoxygenase 61 PGC 1a 61 enzyme HMG CoA 61 paxillin 61 SWI SNF 61 dendritic spine 61 IKK2 61 microRNA 61 FOXP3 61 mRNA decay 61 N Myc 61 biosynthetic pathway 61 CD#L 61 CD# ligand 61 methylation patterns 61 ATPase 61 phosphorylates 61 VE cadherin 61 Rho kinase 61 TLR4 61 β catenin 61 GRK2 61 TG2 61 cypin 61 hyperactivation 61 enzyme phosphodiesterase 61 MMPs 61 gene 60 epigenetic modification 60 MDSCs 60 LXRs 60 extracellular signal 60 tumor metastasis 60 amyloid formation 60 miR 60 mitochondrial function 60 osteopontin 60 cyclic AMP 60 TGFβ 60 small molecule inhibitors 60 GABA receptor 60 demethylation 60 ryanodine receptor 60 glial cell 60 chromatin remodeling complex 60 neural pathway 60 TMEM#B 60 mTOR signaling 60 BDNF 60 mRNA translation 60 palladin 60 cardiac hypertrophy 60 NF kB signaling 60 RhoA 60 neurotransmission 60 methylation 60 osteocalcin 60 glutamate 60 ERK2 60 connexin# 60 ubiquitin ligases 60 homodimers 60 antisense RNA 60 innate immune response 60 GTPases 60 Foxp3 60 Notch receptor 60 POMC neurons 60 TNFα 60 plexin D1 60 epigenome 60 Vascular endothelial growth 60 cell adhesion molecules 60 PHLPP 60 habenula 60 CaM kinase 60 molecular abnormalities 60 cPLA2 60 TNFalpha 60 enzyme COX 60 NFkappaB 60 susceptibility gene 60 P#X# 60 Keap1 60 dystroglycan 60 receptor subtype 60 upregulation 60 downstream effectors 60 HHMI investigator 60 immune cells 60 PTPN# 60 aP2 60 non coding RNA 60 telomere dysfunction 60 Nedd4 60 transferrin receptor 60 morphogens 60 hedgehog signaling pathway 60 genetic underpinnings 60 downregulation 60 androgen receptor AR 60 osteoclast activity 60 fibrogenesis 60 serine protease 60 cdk5 60 dentate gyrus 60 morphogen 60 chromosome condensation 60 COX2 60 JAK STAT pathway 60 insulin signaling pathway 60 caveolae 60 GSK 3ß 60 TSP1 60 melatonin receptor 60 lymphangiogenesis 60 NEDD9 60 Nurr1 60 angiogenesis 60 FMRP 60 HDAC6 60 GATA4 60 tetherin 60 estrogen metabolism 60 pericytes 60 catalytic subunit 60 epigenetic 60 neurotrophic factor 60 Vpu 60 enzymatic activity 60 histone 60 centrosome 60 SOD1 protein 60 epigenetic silencing 60 dynein 60 glycosylation 60 HIP1 60 naturally occurring enzyme 60 WWP2 60 cytokine signaling 60 vitamin D receptors 60 innate immunity 60 ERK signaling 60 microglial cells 60 mutant SOD1 60 MEF2D 60 carbohydrate metabolism 60 PP2A 60 gene mutation 60 SREBP 60 neural circuitry 60 acetylcholine receptor 60 Arp2 3 60 selective inhibition 60 cAMP 60 tau protein 60 CHD7 60 pre mRNA splicing 60 HMGA2 60 NKX#.# 60 4E BP1 60 transcriptional regulators 60 neuronal circuitry 60 #beta HSD1 60 TNF receptors 60 adhesion proteins 60 Nrf2 pathway 60 receptor tyrosine kinase 60 chromosomal regions 60 Tregs 60 hypocretin 60 PML RARA 60 HIF 1α 60 STAT1 60 PHD2 60 leukocyte recruitment 60 neuronal stem cells 60 ligases 60 superoxide dismutase 60 FOXO 60 MECP2 gene 60 XBP 1 60 microglial 60 adaptive immunity 60 miR #b [002] 60 hematopoiesis 60 biosynthesis 60 Hox genes 60 transmembrane receptor 60 RNAi pathway 60 brain derived neurotrophic 60 mesenchymal cells 60 RIP1 59 inhibitory receptors 59 BACE1 59 Clusterin 59 renal fibrosis 59 alternative splicing 59 neural circuits 59 KLF2 59 hepatic stellate cell 59 Phosphorylation 59 molecular biomarkers 59 dopamine receptors 59 beta amyloid peptide 59 NKG2D 59 HDAC2 59 MUC1 * 59 HSP# 59 histone acetylation 59 cilium 59 chitinase 59 beta globin gene 59 Epigenetic 59 adipokine 59 autocrine 59 inhibit angiogenesis 59 Epidermal Growth Factor 59 Hh pathway 59 phosphatase 59 galanin 59 Cathepsin B 59 TRPV3 59 RNA polymerase 59 IL 7R 59 endogenous cannabinoids 59 breast epithelial cells 59 dopaminergic neurons 59 neuronal signaling 59 Salk researchers 59 molecular signaling pathways 59 neurotransmitter 59 Apobec3 59 beta subunit 59 plasminogen 59 netrin 1 59 hepatic stellate cells 59 neurodegeneration 59 sRNA 59 hormone adiponectin 59 HOX genes 59 inhibitory 59 evolutionarily conserved 59 neuregulin 59 IDH1 59 helicase 59 HDAC inhibitors 59 neuronal dysfunction 59 thyroid hormone receptor 59 CB2 receptor 59 p# tumor suppressor 59 TRAF6 59 biochemical signaling pathway 59 HDAC 59 dimerization 59 Aβ 59 myosin II 59 CDK8 59 protein 59 mutant proteins 59 myelination 59 effector functions 59 HPA axis 59 neurotransmitter serotonin 59 ERK 59 mesenchymal transition 59 menin 59 tau tangles 59 c myc gene 59 NADPH oxidase 59 neuronal circuits 59 TRP channels 59 SIR2 59 PKC isoforms 59 neurotrophins 59 miRNA expression 59 cohesin 59 homeobox gene 59 N myc 59 galectin 3 59 nicotinamide 59 prostaglandin synthesis 59 HDAC3 59 TGFß 59 coactivator 59 ectopic expression 59 Siglec 8 59 MALAT1 59 osteoblast 59 TNFa 59 RNAs 59 caspase 59 cyclophilin 59 tropomyosin 59 Ang2 59 NPD1 59 LRP5 59 CXCL# 59 Hh signaling 59 SUMOylation 59 GABAergic neurons 59 Hedgehog signaling pathway 59 protein complexes 59 membrane proteins 59 TRF1 59 Sirt3 59 humanin 59 STIM1 59 ligase 59 STK# [002] 59 epigenetic modifications 59 secretase 59 Androgen receptor 59 glycogen synthase kinase 59 disulfide bond 59 H#K# [002] 59 BubR1 59 enzymes 59 melanocortin receptors 59 glycan 59 RNA sequences 59 FLT3 59 n cofilin 59 urocortin 59 apoptosis 59 VHL gene 59 suppresses tumor 59 amyloid beta protein 59 receptor proteins 59 endocytosis 59 matrix metalloproteinases MMPs 59 dopamine signaling 59 Jhdm2a 59 DNA replication 59 glycogen metabolism 59 Src kinases 59 phytochrome 59 naturally occurring protein 59 microtubule 59 metalloproteinases 59 SMN2 59 acetylcholine receptors 59 protein tyrosine phosphatases 59 neuroinflammation 59 adipogenesis 59 granzyme B 59 PEDF 59 cannabinoid receptor 59 chaperone proteins 59 DNA demethylation 59 Orexin 59 cyclooxygenase 2 59 gene encodes protein 59 epigenetic inheritance 59 remyelination 59 phosphoinositide 3 59 cell adhesion molecule 59 antibody mediated 59 fast skeletal troponin 59 Prox1 59 RSK2 59 γ secretase 59 miR #a [002] 59 cadherin 59 atherogenesis 59 TRPV1 channel 59 adenosine A2A receptor 59 Rab5 59 gene amplification 59 tenascin C 59 messenger RNA 59 amyloid peptide 59 cardiac fibrosis 59 phagocytosis 59 biologic pathway 59 mTOR signaling pathway 59 RKIP 59 caveolin 59 regulate gene expression 59 GABA receptors 59 NF KB 59 sporadic ALS 59 TH# cells 59 interleukin 1beta 59 obestatin 59 PTP 1B 59 methyltransferases 59 NAADP 59 myelin repair 59 NS4B 59 MIF protein 59 signal transduction 59 stathmin 59 adrenergic receptors 59 nerve cells 59 costimulation 59 Dystrophin 59 c Src 59 amyloid cascade 59 endothelial nitric oxide synthase 58 MetAP2 58 ADDLs 58 osteoblast differentiation 58 nucleolus 58 FGFR2 58 lipoprotein metabolism 58 vimentin 58 neuropeptide Y 58 CB1 receptors 58 factor GDNF 58 transcriptional repression 58 Olefsky 58 RAR beta 58 urokinase plasminogen activator 58 Galectin 58 adipokines 58 MEF2A 58 focal adhesion kinase FAK 58 ALDH2 58 MDMX 58 protein tyrosine kinase 58 LRRK2 gene 58 intracellular signaling pathway 58 astrocyte 58 enzymatic pathways 58 VEGF 58 follistatin 58 zebrafish 58 inflammatory cytokines 58 histone code 58 oligodendrocyte 58 genes encoding 58 GTPase