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(Click for frequent words.) 77 insulin resistance 73 abdominal obesity 72 cardiovascular disease 70 NAFLD 69 MetS 69 impaired glucose tolerance 68 hypertension 68 diabetes mellitus 67 atherosclerosis 66 heart disease 66 Metabolic syndrome 66 impaired fasting glucose 66 diabetes 66 C reactive protein 66 prehypertension 65 glucose intolerance 65 cardiovascular mortality 65 metabolic syndrome MetS 65 cardiovascular disease CVD 65 Metabolic Syndrome 65 coronary heart 64 lipid levels 64 gallstone disease 64 subclinical atherosclerosis 64 prediabetes 64 elevated triglycerides 64 adiposity 64 triglyceride levels 64 preeclampsia 64 metabolic syndrome cluster 64 fatty liver disease 64 insulin resistance syndrome 64 postmenopausal breast cancer 63 fasting glucose levels 63 vitamin D deficiency 63 mild cognitive impairment 63 coronary disease 63 microalbuminuria 63 serum cholesterol 62 coronary artery disease 62 onset diabetes 62 disease NAFLD 62 subclinical hypothyroidism 62 cardiometabolic risk 62 polycystic ovary syndrome PCOS 62 folate deficiency 62 blood lipids 62 gene variant 62 uric acid levels 62 HDL cholesterol 62 cardio metabolic 62 cognitive decline 62 gestational diabetes 61 hypercholesterolemia 61 modifiable risk 61 dietary patterns 61 arterial stiffness 61 elevated CRP 61 albuminuria 61 metabolic abnormalities 61 subclinical hyperthyroidism 61 elevated LDL cholesterol 61 waist circumference 60 gene variants 60 depressive symptoms 60 insulin sensitivity 60 endothelial dysfunction 60 fasting insulin 60 cognitive impairment 60 cardiovascular 60 fructose intake 60 obesity 60 lipid abnormalities 60 T2D 60 obese 60 trans palmitoleic acid 60 dysglycemia 60 insulin resistant 59 triglycerides 59 LDL cholesterol 59 diabetes mellitus DM 59 elevated triglyceride levels 59 genetic variants 59 hyperlipidemia 59 alcoholic fatty liver 59 obesity insulin resistance 59 T2DM 59 hyperglycemia 59 endometrial cancer 59 sleep disordered breathing 59 gestational diabetes mellitus 59 fasting glucose 59 elevated homocysteine 59 periodontal disease 59 brain shrinkage 59 hyperglycaemia 59 polycystic ovary syndrome 59 cholesterol 59 hydroxyvitamin D levels 59 narcolepsy cataplexy 59 APOE e4 59 inflammatory markers 59 APOE gene 58 hyperinsulinemia 58 pre eclampsia 58 atherogenic dyslipidemia 58 hypertensive 58 dyslipidemia 58 left ventricular hypertrophy 58 body fatness 58 visceral fat 58 coronary calcification 58 abdominal fat 58 elevated cholesterol 58 glucose tolerance 58 cardio vascular disease 58 LDL cholesterol levels 58 A1 allele 58 Insulin resistance 58 nonalcoholic fatty liver 58 magnesium intake 58 dietary intakes 58 nondiabetic 58 macroalbuminuria 58 abdominal adiposity 58 dietary glycemic index 58 Lp PLA2 58 cognitive function 58 genetic variations 58 genetic variant 58 homocysteine levels 58 thyroid dysfunction 57 hypertensives 57 adiponectin 57 preterm delivery 57 obstructive sleep apnea 57 DASH diet 57 elevated depressive symptoms 57 vegetable intake 57 type2 diabetes 57 serum lipid levels 57 adiponectin levels 57 RBP4 57 cystatin C 57 serum vitamin D 57 2 diabetes T2D 57 T1DM 57 antihypertensive therapy 57 cardiorespiratory fitness 57 nonalcoholic steatohepatitis 57 index BMI 57 colorectal cancer 57 Prehypertension 57 MYH9 gene 57 fatty liver 57 nephropathy 57 bulimia nervosa 57 dietary fat 57 basal cell nevus syndrome 57 familial hypercholesterolemia 57 cardiovascular diseases 57 carotid atherosclerosis 57 bone density 57 osteoporosis 57 lipoprotein 57 fetuin 57 central adiposity 57 systemic lupus erythematosus SLE 57 androgen deficiency 57 glucose metabolism 57 atherosclerotic disease 57 amnestic MCI 57 prediabetic 57 folate 57 Prediabetes 57 thyroid function 57 osteopenia 57 knee OA 56 calcium supplementation 56 pre menopausal 56 colorectal adenomas 56 knee osteoarthritis 56 hydroxyvitamin D 56 dietary sodium 56 homocysteine 56 HbA1c levels 56 CHD mortality 56 aldosterone 56 Stop Hypertension diet 56 MGUS 56 Diabetes Mellitus 56 dietary intake 56 CHD 56 LDL C 56 cardiac hypertrophy 56 retinopathy 56 systemic lupus erythematosus 56 APOL1 56 anovulatory infertility 56 folate intake 56 serum phosphate 56 artery calcification 56 HDL2 56 elevated blood glucose 56 untreated celiac disease 56 GERD 56 lipid metabolism 56 diabetic retinopathy 56 colorectal adenoma 56 fasting blood glucose 56 serum uric acid 56 folate supplementation 56 dietary calcium intake 56 tHcy 56 Hypertension 56 nonfasting triglycerides 56 sudden cardiac death 56 dietary calcium 56 metabolic disturbances 56 diabetes mellitus T2DM 56 APOE4 56 Vitamin D insufficiency 56 cardiovascular disease hypertension 56 plasma lipid 56 endothelial function 56 cholesterols 56 abnormal lipids 55 oxidative stress 55 hypothyroidism 55 glycosylated hemoglobin HbA1c 55 chronic pancreatitis 55 nicotine dependence 55 autonomic dysfunction 55 statins 55 prostate carcinogenesis 55 glycemia 55 lipoprotein levels 55 abnormal lipid 55 vascular dysfunction 55 abnormal lipid levels 55 esophageal adenocarcinoma 55 hepatic steatosis 55 vascular disease 55 Framingham Offspring Study 55 potentially modifiable 55 systemic inflammation 55 vitamin D insufficiency 55 parkinsonism 55 rs# [002] 55 adrenal function 55 nonalcoholic steatohepatitis NASH 55 adenoma 55 fasting plasma glucose 55 perimenopausal women 55 anorexia nervosa 55 non fasting triglycerides 55 glycemic diet 55 genetic variants associated 55 proliferative diabetic retinopathy 55 serum lipids 55 cardiovascular morbidity 55 MYH9 55 polyp recurrence 55 systolic hypertension 55 statin therapy 55 depressive disorders 55 density lipoprotein cholesterol 55 periodontitis 55 shorter telomeres 55 diabetic nephropathy 55 ApoE4 55 myocardial infarction 55 coronary artery calcification 55 leptin resistance 55 endometrial hyperplasia 55 familial adenomatous polyposis 55 glitazones 55 macrovascular disease 55 prehypertensive 55 TZDs 55 metabolic dysfunction 55 atherosclerosis hardening 55 hyperhomocysteinemia 55 hyperphosphatemia 55 Hashimoto thyroiditis 55 familial pancreatic cancer 55 hyperuricemia 55 apoC III 55 comorbidity 55 inflammatory bowel disease 55 colorectal neoplasia 55 vitamin B# deficiency 55 serum triglycerides 55 albumin excretion 55 calcium intake 55 primary biliary cirrhosis 55 ischemic stroke 55 colorectal polyps 55 Alzheimers disease 55 APOE e4 gene 55 systolic blood pressure 55 saturated fat intake 55 Alzheimer Disease AD 55 Vitamin D deficiency 55 IDDM 55 elevated uric acid 55 oxidized LDL 55 CETP gene 54 Genetic variants 54 bad cholesterol LDL 54 hematopoietic cancers 54 Lp PLA 2 54 carotid IMT 54 vitamin B6 54 fat diets 54 genetic predisposition 54 modifiable lifestyle 54 transferrin saturation 54 elevated LDL 54 hsCRP 54 glycemic load 54 PTEN mutations 54 vitamin D 54 ABCB1 54 liver fibrosis 54 Alzheimer disease AD 54 coronary artery calcium 54 hypovitaminosis D 54 elevated fasting glucose 54 rs# [003] 54 haptoglobin 54 dyslipidaemia 54 cortisol levels 54 Diabetes mellitus 54 diabetes cardiovascular disease 54 telomere length 54 TCF#L# 54 remnant lipoproteins 54 intra abdominal fat 54 APOE ε4 54 hyperlipidaemia 54 insulin secretion 54 lipid profiles 54 NKX2 54 c reactive protein 54 myocardial ischemia 54 phytoestrogens 54 lipid disorders 54 polycystic ovarian syndrome 54 hereditary predisposition 54 thyrotropin levels 54 genetic variation 54 mood disorders 54 genotype 54 lipid lowering medications 54 preserved ejection fraction 54 Homocysteine 54 APOE 54 dietary folate 54 obese adolescents 54 bone mineral 54 cognitively normal 54 premenstrual syndrome PMS 54 genetic polymorphisms 54 caffeine intake 54 cerebral infarction 54 Obstructive sleep apnea 54 serum calcium 54 FTO gene 54 homozygous familial hypercholesterolemia 54 COPD 54 Sarcopenia 54 behavioral disinhibition 54 colorectal tumors 54 sporadic ALS 54 soy isoflavones 54 atopy 54 homocysteine concentrations 54 lowfat diet 54 gout 54 postoperative AF 54 chronic diseases 54 atopic disease 54 Alzheimer disease 54 binge eating 54 irritable bowel syndrome IBS 54 G allele 54 extrapyramidal symptoms 54 uric acid 54 thiazide diuretics 54 underactive thyroid 54 cardio respiratory fitness 54 angiotensin receptor blockers ARBs 54 hyperkalemia 54 diabetes dyslipidemia 54 CVD mortality 54 primary ovarian insufficiency 54 resistant hypertension 54 Chronic insomnia 54 gamma tocopherol 54 chronic kidney 54 gum disease 54 cryptorchidism 54 Cardiovascular Risk 54 autoantibodies 53 glycated hemoglobin levels 53 atopic 53 diverticulosis 53 Stop Hypertension DASH diet 53 kidney function 53 hyperparathyroidism 53 macrovascular 53 LUTS 53 nonfasting triglyceride levels 53 attention-deficit/hyperactivity disorder ADHD 53 precocious puberty 53 triglyceride concentrations 53 metabolic 53 telomere lengths 53 BRCA1 mutations 53 atherogenic 53 irregular menstrual cycles 53 sarcopenia 53 belly fat 53 comorbidities 53 lactose malabsorption 53 celiac disease 53 statin 53 stone formers 53 amino acid homocysteine 53 serum IGF 53 colorectal cancer CRC 53 dietary antioxidants 53 benign breast 53 serum glucose 53 atherosclerotic cardiovascular disease 53 silent myocardial ischemia 53 fructose intolerance 53 density lipoprotein HDL cholesterol 53 fructose diet 53 AAT deficiency 53 triacylglycerol concentrations 53 microvascular complications 53 iron overload 53 alpha carotene 53 dopamine receptor gene 53 white matter hyperintensities 53 HNPCC 53 underactive thyroid gland 53 untreated sleep apnea 53 recurrent wheezing 53 proteinuria 53 urinary symptoms 53 Coronary artery calcification 53 normotensive 53 abnormal glucose tolerance 53 impaired glucose metabolism 53 juvenile idiopathic arthritis JIA 53 microvascular disease 53 isolated systolic hypertension 53 psychotic symptoms 53 carotid bruit 53 leptin 53 hypocaloric diet 53 adenomas 53 atherothrombotic disease 53 testosterone supplementation 53 Chronic Kidney Disease 53 STAT4 53 ADPKD 53 fasting triglyceride levels 53 HbA1C 53 mitochondrial mutations 53 AAT Deficiency 53 Binge eating 53 asymptomatic 53 serum leptin 53 dietary fats 53 attention-deficit/hyperactivity disorder 53 open angle glaucoma 53 blood glucose levels 53 systolic dysfunction 53 airway hyperresponsiveness 53 prostate cancer CaP 53 distal colon cancer 53 Nonalcoholic Fatty Liver Disease 53 nonvertebral fractures 53 plasma folate 53 thyroid hormone levels 53 dietary supplementation 53 juvenile idiopathic arthritis 53 VLDL cholesterol 53 serum triglyceride levels 53 polycystic ovarian syndrome PCOS 53 LDL 53 carotid plaque 53 lobular breast cancer 53 psychiatric disorders 53 inadequate calcium intake 53 postmenopausal 53 psychotic disorders 53 habitual snoring 53 onset diabetes mellitus 53 GSTP1 53 transaminase levels 53 SE alleles 53 diabetic kidney 53 gestational hypertension 53 glucose homeostasis 53 improves insulin sensitivity 53 hereditary hemochromatosis 53 esophageal squamous cell carcinoma 53 LDL HDL ratio 53 menarche 53 overt hypothyroidism 53 HMGA1 53 severely obese 53 serum calcium levels 53 vascular dementia 53 Helicobacter pylori infection 53 folic acid intake 53 antidiabetic medication 53 premenopausal breast cancer 53 abdominally obese 53 hypothalamic amenorrhea 53 slow metabolizers 53 LQTS 53 hypothyroid 52 Barrett esophagus 52 lung function 52 ApoE4 gene 52 atrial fibrillation 52 heterozygous familial 52 anxiety disorders 52 hippocampal volume 52 IGFBP 52 diastolic heart 52 calcium intakes 52 ovulatory infertility 52 urate levels 52 vitamin D deficient 52 low density lipoprotein 52 #mg/dL [001] 52 GSTT1 52 serum folate 52 waist circumferences 52 PPAR γ 52 Atherosclerosis 52 inflammatory polyarthritis 52 Physical inactivity 52 Lipoprotein 52 LDLs 52 mtDNA mutations 52 late onset hypogonadism 52 dietary fiber intake 52 tibolone 52 FTLD 52 Sleep disordered breathing 52 gastric carcinogenesis 52 HNSCC 52 plasma lipids 52 serum GGT 52 arterial thickening 52 C Reactive Protein 52 metformin 52 impaired cognition 52 subclinical 52 Reynolds Risk Score 52 waist girth 52 serum creatinine levels 52 arterial hypertension 52 glycated hemoglobin 52 diabetes hyperlipidemia 52 urolithiasis 52 overt nephropathy 52 alanine aminotransferase ALT 52 iron deficient 52 amnestic mild cognitive impairment 52 serum ferritin 52 polymorphism 52 HGPS 52 hypertension diabetes mellitus 52 rs# [001] 52 ALDH2 52 disordered eating behaviors 52 hypertensive patients 52 Mediterranean diet 52 ApoE 52 depressive symptomatology 52 skeletal fluorosis 52 fatty acid oxidation 52 postprandial insulin 52 co morbidities 52 Ascherio 52 adiponectin concentrations 52 LPA gene 52 pramlintide 52 mitochondrial dysfunction 52 colorectal carcinogenesis 52 Proteinuria 52 metabolically healthy 52 CC genotype 52 neovascular AMD 52 HDL C 52 triglyceride concentration 52 islet autoimmunity 52 EBV infection 52 gene mutation 52 thyrotropin 52 estrogen metabolism 52 atopic eczema 52 sleep apnea 52 CAG repeats 52 pubertal 52 phytoestrogen 52 autoimmune thyroid 52 Haptoglobin 52 SNPs 52 dietary modification 52 atherosclerotic 52 GSTM1 52 saturated fatty acids 52 GH deficiency 52 H. pylori infection 52 flavanol rich foods 52 diabetics 52 lowering LDL cholesterol 52 MTHFR 52 Severe Primary IGFD 52 artherosclerosis 52 APOE genotype 52 mitochondrial toxicity 52 severe periodontitis 52 motor neuron degeneration 52 resistin 52 serum urate levels 52 neuroendocrine 52 loop diuretics 52 plasma homocysteine levels 52 Gestational diabetes 52 gestational diabetes mellitus GDM 52 glucose intolerant 52 estrogen deficiency 52 lowering cholesterol 52 thyroid disorders 52 serum parathyroid hormone 52 cholesterol LDL C 52 airway inflammation 52 periodontal infections 52 somatic symptoms 52 exfoliation glaucoma 52 familial clustering 52 triacylglycerol 52 inflammatory rheumatic 52 blood glucose concentrations 52 cardiac fibrosis 52 primary aldosteronism 52 kaempferol 52 SHPT 52 fasting hyperglycemia 52 colon polyps 52 urinary calcium 52 reflux symptoms 52 atherothrombosis 52 alexithymia 52 IUGR 52 fat diet 52 recurrent acute pancreatitis 52 ACE inhibitors 52 BRCA2 mutations 52 testicular germ cell 52 clusterin 52 Hb A1C 52 fat hormone leptin 52 underlying pathophysiology 52 inflammatory biomarkers 52 iron deficiency 51 HPA axis 51 carbohydrate intolerance 51 aneuploidy 51 Adiponectin 51 atypical hyperplasia 51 hypercalciuria 51 alcoholic cirrhosis 51 PSA velocity 51 elevated liver enzymes 51 hemoglobin A1c levels 51 highest tertile 51 gene variation 51 shorter telomere length 51 serum PSA 51 Stop Hypertension 51 left ventricular dysfunction 51 contrast induced nephropathy 51 coronary calcium 51 Abdominal fat 51 major depressive disorder 51 venous thrombosis 51 vasomotor symptoms 51 non aspirin NSAIDs 51 advanced adenoma 51 plasma homocysteine 51 STK# gene 51 oesophageal adenocarcinoma 51 TMEM#B 51 Aortic stenosis 51 disc degeneration 51 telomere shortening 51 antioxidant intake 51 APOE e4 allele 51 salt intake 51 SORL1 51 nondiabetics 51 brain atrophy 51 Obesity 51 plasma triglycerides 51 atherosclerotic vascular disease 51 serum selenium 51 metabolic acidosis 51 macronutrient intake 51 calcium oxalate stones 51 nutrient intake 51 venous thromboembolism 51 Dietary Approaches 51 dementia 51 DRD2 51 kidney disease 51 penetrance 51 TCF#L# gene 51 statin medications 51 disease CHD 51 chronic periodontitis 51 hypercholesterolaemia 51 Sjögren syndrome 51 CYP#C# [001] 51 polyphenol 51 amenorrhea 51 genetic susceptibility 51 hypertrophy 51 Fatty Liver Disease 51 premenopausal 51 urinary tract symptoms LUTS 51 psychosocial variables 51 hemochromatosis 51 CARDIA 51 highest quintile 51 HbA 1c 51 dysregulation 51 pathophysiologic 51 cardiac insufficiency 51 calorie diets 51 ketogenic 51 E selectin 51 osteoporotic fracture 51 SRBD 51 bowel polyps 51 Parkinson disease PD 51 Major depressive disorder 51 lipohypertrophy 51 coronary atherosclerosis 51 multivitamin supplements 51 LDL cholesterol concentrations 51 insulin resistance precursor 51 IgA deficiency 51 dietary fiber 51 familial ALS 51 Abdominal obesity 51 urinary albumin 51 vitamin D intake 51 paraneoplastic 51 recurrent miscarriage 51 subclinical inflammation 51 persistent pulmonary hypertension 51 serum homocysteine 51 serum folate concentrations 51 hormone therapy estrogen 51 glycated hemoglobin HbA1c 51 POAG 51 ADHD 51 SIRT1 51 tic severity 51 visceral adiposity 51 DHEAS 51 postoperative delirium 51 systolic 51 Nonalcoholic fatty liver 51 nonmelanoma skin cancer 51 lipid lowering therapy 51 hypospadias 51 hsCRP levels 51 angiotensin converting enzyme 51 neuropsychiatric disorder 51 progressive dyspnea 51 pulmonary hypertension PH 51 AUDs 51 BRCA mutation 51 serum PTH 51 flavonoid intake 51 baseline HbA1c 51 antihypertensive drugs 51 hormone aldosterone 51 urinary albumin excretion 51 obese postmenopausal 51 metabolic parameters 51 B# deficiency 51 polyphenol content 51 glucocorticoid 51 cardiometabolic syndrome 51 acute myelogenous leukemia AML 51 lipoprotein metabolism 51 SHBG 51 postoperative pulmonary 51 HIV HCV coinfected 51 PCOS 51 aminotransferase levels 51 Osteopenia 51 cholesterol HDL 51 rheumatoid arthritis RA 51 diastolic function 51 uncontrolled asthma 51 muscle dysmorphia 51 Alzheimer pathology 51 Elevated triglycerides 51 trigylcerides 51 premenopausal women 51 caloric restriction 51 cirrhosis 51 antioxidant enzyme 51 postmenopausal women 51 endogenous estrogen 51 coronary artery aneurysms 51 PUFA intake 51 secondary hyperparathyroidism 51 recurrent UTI 51 genetic determinants 51 MMSE scores 51 arterial stiffening 51 serum potassium 51 CYP#C# gene 51 genotypes 51 glomerular filtration rate 51 plasma selenium 51 intensive statin therapy 51 nephrolithiasis 51 Vitamin B# deficiency 51 PON1 activity 51 antihypertensive medications 51 neural tube defect 51 #p# [001] 51 CLA supplementation 51 intima media thickness 51 carbohydrate intake 51 NF1 51 vertebral fracture 51 disease progression 51 humanin 51 flavonoids 51 diabetes hypertension 51 Depressive symptoms 51 pre eclamptic 51 Buijsse 51 spontaneous preterm delivery 51 bone resorption 51 glycosylated hemoglobin 51 subclinical cardiovascular disease 50 platelet reactivity 50 arterial calcification 50 neuropsychiatric disorders 50 mIU L 50 ORMDL3 50 cognitive dysfunction 50 nonobese 50 ApoE gene 50 monounsaturated fatty acids 50 psychosocial functioning 50 preterm birth 50 thrombotic events 50 carotid intima media 50 ovarian hormones 50 amyloid deposition 50 improves glycemic 50 soluble CD# ligand 50 isoflavones 50 orofacial clefts 50 Klinefelter syndrome 50 APOE allele 50 lactic acidosis 50 APOC3 50 BRCA mutations 50 Anorexia nervosa 50 FMRP protein 50 genetically susceptible 50 undergoing bariatric surgery 50 hip BMD 50 RBP4 levels 50 Genetic predisposition 50 linoleic acid 50 periodontal diseases 50 psychotic illness 50 metabolic abnormality 50 antioxidant nutrients 50 urinary oxalate 50 Migraine headaches 50 serum BDNF 50 antihypertensive medication 50 SHBG levels 50 neurological abnormalities 50 autoimmune thyroiditis 50 nitrotyrosine 50 NHANES III 50 vascular inflammation 50 hypercoagulable 50 Major Depressive Disorder 50 apolipoprotein B 50 atherosclerotic lesions 50 binge eating disorders 50 klotho 50 cortisol secretion 50 rheumatic disease 50 hypoglycemia 50 polyunsaturated fatty acids 50 hypertensive rats 50 calorie restriction 50 serum retinol 50 hyperinsulinemic 50 urate 50 Hyperlipidemia 50 URTI 50 hs CRP 50 #q# [001] 50 valproate 50 essential thrombocythemia 50 hormone adiponectin 50 BMI percentile 50 IL6 50 UCP2 50 cardiomyopathies 50 valvular disease 50 PTPN# 50 multifactorial 50 dietary interventions 50 Grodstein 50 comorbid disorders 50 Von Willebrand disease 50 COMT gene 50 systolic BP 50 thrombophilia 50 oxidized cysteine 50 breast cancer metastasis 50 non alcoholic steatohepatitis 50 CKD 50 Polycystic ovary syndrome PCOS 50 carotid plaques 50 Insulin Resistance 50 GRK5 50 zinc deficiency 50 liver cirrhosis 50 isoflavone intake 50 antigen PSA 50 prothrombotic 50 restless legs 50 steatohepatitis 50 elevated serum creatinine 50 preterm deliveries 50 Waist circumference 50 Bibbins Domingo 50 ALLHAT 50 folate vitamin B 50 disordered eating 50 renal disease 50 nondepressed 50 observational studies 50 vitamin D inadequacy 50 atypical neuroleptics 50 gallstone formation 50 Cognitive impairment 50 recurrent stroke 50 triglyceride 50 Clinical Nutrition 50 heterozygotes 50 chronic prostatitis 50 EGFR mutations 50 Wernicke Korsakoff syndrome 50 LRP5 50 Darapladib 50 sCJD 50 postmenopausal hormone therapy 50 noncardiovascular mortality 50 kidney dysfunction 50 fructose intolerant 50 mixed hyperlipidemia 50 Leitzmann 50 Irritable bowel syndrome IBS 50 ARIs 50 macrovascular complications 50 phenotypes 50 XMRV infection 50 euthyroid 50 cardioembolic stroke