Related by context. All words. (Click for frequent words.) 72 polymorphisms 71 SNPs 71 haplotypes 69 alleles 68 genes encoding 68 genetic loci 68 chromosomal regions 68 haplotype 67 genotypes 67 missense mutations 67 gene variants 67 #q# [001] 67 genetic variants 67 miRNAs 66 chromosome #q# [001] 66 intron 66 susceptibility genes 66 CNVs 66 rs# [003] 66 genes 65 nucleotide sequence 65 intergenic 65 coding sequences 65 mutations 65 phenotype 65 quantitative trait loci 64 miRNA expression 64 orthologs 64 mRNA expression 64 #S rRNA 64 homologs 64 PALB2 64 methylation patterns 64 noncoding RNAs 64 QTLs 63 #q#.# [002] 63 polymorphism 63 intronic 63 linkage disequilibrium 63 isoforms 63 DNA sequences 63 phenotypes 63 pseudogenes 63 chromosome #q# [002] 63 susceptibility loci 63 indel 63 rs# [002] 63 rs# [001] 62 allelic 62 autism susceptibility genes 62 single nucleotide polymorphism 62 microsatellite markers 62 histone modifications 62 #p#.# [001] 62 phylogenetic analyzes 62 rs# [004] 62 causal variants 62 exons 62 differentially expressed genes 62 genetic markers 62 paralogs 62 VNTR 62 chromosome #p#.# 62 gene expression 61 promoter methylation 61 chromosome #q 61 germline mutations 61 microdeletions 61 transcriptome 61 heterozygotes 61 chromosome #q#.# [001] 61 hypermethylated 61 methylation 61 indels 61 somatic mutations 61 microRNA expression 61 MLH1 61 splice variants 61 chromosome #p# [001] 61 genomic loci 61 allelic variants 61 hypermethylation 61 susceptibility gene 61 #q# [002] 61 UTRs 61 KIAA# 61 gene mutations 60 receptor binding 60 ncRNAs 60 genetic variants associated 60 PTPN# 60 IL#B 60 mRNA transcripts 60 transcriptomes 60 functional polymorphism 60 genotype 60 clades 60 allele 60 amino acid sequences 60 EGFR mutations 60 allele frequencies 60 kilobases 60 mRNAs 60 gene expression profiles 60 rRNA 60 transcriptional regulation 60 autosomal 60 chromosomal rearrangements 60 H#K#me# 60 heterozygous 60 imprinted genes 60 gene loci 60 #p#.# [002] 60 miRNA genes 60 ZNF# 60 C#Y 60 3'UTR 59 Alu elements 59 yeast genome 59 microRNA molecules 59 bacterial genomes 59 HLA DRB1 59 GSTM1 59 genotyped 59 homology 59 gene expression patterns 59 ultraconserved elements 59 gene polymorphisms 59 SLC#A# [002] 59 genomes 59 amino acid sequence 59 gene locus 59 mtDNA 59 cDNAs 59 subcellular localization 59 sequence homology 59 homologues 59 DLC1 59 genetic variations 59 Clusterin 59 missense mutation 59 ERBB2 59 SNP rs# [001] 59 homozygosity 59 splice junctions 59 KLF4 59 mutational 59 virulence genes 59 coding exons 59 genetic polymorphisms 58 subtypes 58 A. thaliana 58 #q#.# [001] 58 genome 58 codons 58 CDKN2A 58 transcriptional 58 Supplementary Fig 58 microRNAs 58 gene 58 FGFR2 58 chromosome #p# [002] 58 nucleotide 58 amino acid substitutions 58 mutation 58 amino acid residues 58 orthologous 58 MSH2 58 nucleotide sequences 58 intergenic regions 58 segmental duplications 58 exon 58 ALK mutations 58 PTEN mutations 58 cM 58 heterozygosity 58 allelic variation 58 operon 58 amplicon 58 transcription factors 58 protein kinases 58 coding genes 58 cDNA libraries 58 sporadic ALS 58 constitutively expressed 58 ORFs 58 CpG 58 methylated 58 #p# [001] 58 vimentin 58 chromosome 58 noncoding 58 peptide sequences 58 uPAR 58 MTHFR 58 tRNA genes 58 MAPK pathway 58 RNA sequences 58 CpG islands 57 susceptibility locus 57 caveolin 57 LIS1 57 kilobase 57 isoform 57 fig. S1 57 genomewide 57 methylated DNA 57 dysbindin 57 mRNA 57 Haplotype 57 non coding RNAs 57 mitochondrial genomes 57 genetic mutations 57 nucleotide substitutions 57 genes BRCA1 57 LPA gene 57 DNA methylation 57 mammalian genomes 57 conserved sequences 57 HLA DR 57 centromere 57 centromeres 57 TCF#L# 57 phenotypic variation 57 inbred strains 57 ortholog 57 chromatin structure 57 genetic alterations 57 microdeletion 57 5 HTTLPR 57 untranslated regions 57 heterochromatin 57 globin genes 57 homozygotes 57 DARPP 57 DRD2 57 spontaneous mutations 57 operons 57 SNP rs# [002] 57 mutant allele 57 genotypic 57 genomic alterations 57 NNRTI resistance 57 KRAS mutations 57 sequenced genomes 57 contigs 57 substrate specificity 57 tumor suppressor gene 57 tyrosine phosphorylation 57 proto oncogene 57 isotypes 57 BDNF gene 57 GSTP1 57 gene encoding 57 MECP2 gene 57 Genetic variants 57 autoantibodies 57 mRNA molecules 57 amplicons 57 alpha synuclein gene 57 monogenic 56 phenotypic 56 overexpression 56 mitochondrial DNA mtDNA 56 haplogroups 56 chromosomal 56 #p# [003] 56 cytokeratin 56 endophenotypes 56 IKZF1 56 PTEN gene 56 microRNA miR 56 acetylation 56 inherited mutations 56 IgA deficiency 56 HOTAIR 56 clusterin 56 heterochromatic 56 LRRK2 gene 56 Genotypes 56 Arabidopsis genes 56 phenotypic traits 56 recombination hotspots 56 eukaryotic 56 orthologous genes 56 frameshift mutation 56 genomic DNA 56 RASSF1A 56 mitochondrial gene 56 SMAD4 56 genetic polymorphism 56 CagA 56 CDH1 56 telomere lengths 56 E#F# 56 gene sequences 56 Jhdm2a 56 TRAF1 C5 56 protein encoded 56 RRM1 56 chromosomal alterations 56 micro RNA 56 RUNX3 56 differentially expressed proteins 56 ribosomal protein 56 segmental duplication 56 proteome 56 histone H3 56 chromosomal aberrations 56 MYH9 56 transgene expression 56 genomic 56 DNA methylation patterns 56 LRAT 56 ribosomal DNA 56 mtDNA mutations 56 PICALM 56 chromosome #q#.# [002] 56 cytochrome b 56 deacetylation 56 3' UTR 56 miRNA 56 mutated genes 56 homozygous 56 subfamilies 56 lymph node metastasis 56 nucleolar 56 chromosomes 56 TOP2A 56 miR #b [002] 56 differentially expressed 56 HMGA2 56 kDa 55 CHEK2 55 lincRNA 55 microcephalin 55 protein isoforms 55 transcriptionally 55 BAC clones 55 kinases 55 codon 55 unmethylated 55 HLA genes 55 penetrance 55 molecular markers 55 HLA alleles 55 microarray experiments 55 lincRNAs 55 BRAF V#E 55 cDNA 55 eotaxin 55 activating mutations 55 transmembrane 55 primate genomes 55 karyotypes 55 valine 55 EBNA1 55 miR #a [001] 55 genomic sequences 55 downregulated 55 binding affinity 55 TACI mutations 55 insertions deletions 55 cyclin E 55 centrosome 55 #S rRNA gene 55 histone modification 55 fig. S4 55 E cadherin 55 immunostaining 55 sRNA 55 Immunohistochemical analysis 55 genetic variant 55 CAG repeats 55 heterodimers 55 phosphorylation 55 posttranslational modifications 55 NF1 gene 55 metalloprotease 55 cytoplasmic 55 splice variant 55 kDa protein 55 epigenetic mechanisms 55 FMR1 gene 55 mitochondrial 55 epigenetic alterations 55 D. melanogaster 55 histone 55 ribosomal proteins 55 centromeric 55 EphB4 55 membrane proximal 55 proteins 55 alternative splicing 55 genetic variation 55 DNMT1 55 CISH 55 PRNP 55 epitopes 55 proteomes 55 chromosomal rearrangement 55 biomarkers 55 proteins encoded 55 Rap1 55 TCF#L# gene 55 hepatocellular carcinomas 55 cytosine methylation 55 5 hmC 55 HLA DQ2 55 K ras mutations 55 CpG island 55 genomic variation 55 causative mutations 55 RNA transcripts 55 APOC3 55 cysteines 55 probands 55 epitope 55 K#R [002] 55 Chromosome 55 non coding RNA 55 apoE 55 array CGH 55 p# mutation 55 receptor gene 55 homodimers 55 transfected 55 telomeric 55 gene duplications 55 phenotypically 55 proband 55 maternally inherited 55 histone acetylation 55 homologous 55 At#g# 55 OCA2 55 SH#B# 55 overexpressed 55 APOE e4 55 PTP1B 55 archaeal 54 circadian genes 54 lymph node metastases 54 epigenetic modification 54 p# activation 54 Drosophila genome 54 C1q 54 phosphorylated 54 serine threonine kinase 54 gene amplification 54 dinucleotide 54 epistasis 54 exomes 54 genetic determinants 54 homodimer 54 dopamine transporter gene 54 selective antagonists 54 epigenetically 54 tumor suppressor genes 54 major histocompatibility complex 54 COL#A# 54 genetic aberrations 54 heritable 54 familial ALS 54 vitamin D receptor 54 RNAs 54 IGFBP 54 genome rearrangements 54 CD#b 54 monozygotic twins 54 microsatellite instability 54 transmembrane domains 54 TP# mutations 54 CNTNAP2 54 DRD2 gene 54 hypomethylation 54 quantitative RT PCR 54 phylogenies 54 GSTT1 54 coexpression 54 luciferase reporter 54 evolutionarily conserved 54 taxa 54 VHL gene 54 extracellular domains 54 micro RNAs 54 catechol O methyltransferase 54 herpesviruses 54 genes differentially expressed 54 Supplementary Table 54 cadherin 54 S#A# [002] 54 chromosomal deletions 54 cyclin D1 54 isoenzymes 54 rs# rs# 54 proline rich 54 circadian clock genes 54 transcriptional activation 54 DISC1 54 mitochondrial genes 54 subunit 54 c Myb 54 parkin gene 54 perilipin 54 MLL2 54 alternatively spliced 54 5 hydroxymethylcytosine 54 MC4R gene 54 fungal genomes 54 heterozygote 54 postsynaptic 54 Fig. 1C 54 breast carcinomas 54 distinct subtypes 54 maize genome 54 SCN5A 54 methyltransferase 54 miR #a [002] 54 tumor suppressor protein 54 upregulated 54 PON1 54 epigenetic silencing 54 PPARg 54 CYP#D# gene 54 sCJD 54 methylated genes 54 mitogen activated protein kinase 54 polyadenylation 54 karyotype 54 SLITRK1 54 enterotypes 54 #q# deletion 54 cysteine residues 54 genetic locus 54 IL#R 54 molecular subtypes 54 cis regulatory 54 nucleosome 54 previously uncharacterized 54 TP# gene 54 RNA binding 54 BARD1 54 piRNAs 54 pathogenic mutations 54 glycosylation 54 lymphoblastoid cell lines 54 hamartomas 54 beta1 integrin 54 dimerization 54 ncRNA 54 TSC1 54 HDACs 54 serine 54 metazoans 54 noncoding RNA 54 amyloidogenic 54 eukaryote 54 EGFR gene 54 endonuclease 54 mice lacking 54 STAT3 54 biochemical marker 53 UGT#B# 53 MLL gene 53 mitochondrial genome 53 PCa 53 CGG repeats 53 mutant alleles 53 Fig. 1A 53 familial pancreatic cancer 53 QTL 53 single nucleotide polymorphisms 53 oxytocin receptor 53 nanomolar 53 inactivating mutations 53 proapoptotic 53 ESR1 53 GTPase 53 histologically 53 VEGF receptor 53 H#K# [002] 53 enolase 53 uncharacterized genes 53 CHI#L# 53 transcription factor 53 immunoblotting 53 methylenetetrahydrofolate reductase 53 constitutively active 53 CRISPR Cas 53 oligonucleotide probes 53 mammalian genome 53 GLUT1 53 protein coding 53 uncharacterized 53 gene rearrangements 53 C. neoformans 53 metazoan 53 bcl 2 53 ABCB1 53 TMPRSS2 ERG fusion 53 biological pathways 53 glycan 53 adenocarcinomas 53 short hairpin RNAs 53 GPC5 53 microsatellite loci 53 breast cancer subtypes 53 CCL#L# 53 cellular pathways 53 tumor biopsies 53 IDH1 gene 53 PAK1 53 R#W [002] 53 STK# [002] 53 isotype 53 histone H4 53 causative genes 53 miRNAs miR 53 homozygote 53 breast cancer genes BRCA1 53 androgen receptor gene 53 CD1d 53 hierarchical clustering 53 estrogen receptor 53 Sanger sequencing 53 histone deacetylases 53 MDM2 53 TNFalpha 53 PKC isoforms 53 sarcosine 53 ADAM# 53 somatic mutation 53 ribosomal RNA rRNA 53 genotyping arrays 53 SPINK1 53 paternally inherited 53 ß catenin 53 BRAF protein 53 hypervariable 53 FLT3 53 viral genomes 53 genetic alteration 53 ADRB2 53 immunohistochemical staining 53 homologous genes 53 missense 53 pleiotropic 53 promoter hypermethylation 53 FGF signaling 53 TIMP 53 aberrant methylation 53 colocalization 53 MC1R gene 53 iNOS 53 transmembrane protein 53 metabolic pathways 53 phosphatases 53 ligand receptor 53 CDK4 53 NPY gene 53 modifier genes 53 mutant enzymes 53 tyrosine kinases 53 DLX5 53 Vps# 53 homolog 53 HFE gene 53 thrombospondin 53 immunohistochemical 53 multigenic 53 #S rRNA genes 53 Htt 53 WNK1 53 differential gene expression 53 MYH9 gene 53 chromosome aberrations 53 genomic deletions 53 mitochondrial proteins 53 transactivation 53 MAPK 53 estrogen receptor alpha 53 fascin 53 heritability 53 chimpanzee genomes 53 caveolin 1 53 M. pneumoniae 53 Plasmodium vivax 53 lymphoid 53 transcriptome sequencing 53 chromosomal translocations 53 vertebrate genomes 53 superfamily 53 HG PIN 53 shRNAs 53 ALK gene 53 homologue 53 protein tyrosine phosphatase 53 PKD1 53 viral RNA 53 coactivator 53 CYP#E# gene 53 EF Tu 53 miRNA molecules 53 tRNA synthetase 53 Foxp3 53 presenilin 53 PIK3CA 53 AMACR 53 synteny 53 β 53 IDH1 mutation 53 metabolic abnormalities 53 polyploid 53 aneuploidies 53 TMEM#B 52 chromosomal DNA 52 proteolytic cleavage 52 FGFR3 52 CYP#E# 52 causative mutation 52 secreted proteins 52 lineages 52 transcriptional repressor 52 variant allele 52 NFKBIA 52 SNP arrays 52 introns 52 FGFR4 52 Activating mutations 52 T2D 52 eIF4E 52 outer membrane proteins 52 metabolites 52 cytosolic 52 MetS 52 chromatin 52 condensin 52 chromosomal abnormalities 52 DQB1 * 52 obstructive coronary artery 52 ligand binding 52 genes CYP#C# 52 K#N 52 glycoproteins 52 Wwox 52 noncoding regions 52 rRNA genes 52 nucleoli 52 X chromosome 52 dimers 52 deuterostomes 52 zebrafish genome 52 cytosine 52 phylogenetic analysis 52 #S rDNA 52 thioredoxin 52 differentially regulated 52 RNA polymerases 52 p# mutations 52 P. falciparum 52 PrPSc 52 prostate cancer CaP 52 trimer 52 matK 52 matrix metalloproteinase 52 serine protease 52 ChIP seq 52 rDNA 52 enzymatic activity 52 H#K# [001] 52 carcinoembryonic antigen 52 MeCP2 gene 52 gene fusions 52 DRD4 52 morphological 52 MC4R 52 cell adhesion molecule 52 ERalpha 52 colorectal carcinomas 52 eukaryotic genomes 52 hepatoma 52 receptor kinase 52 MiRNAs 52 serum concentrations 52 HLA antigens 52 cDNA microarray 52 tetramers 52 Polymorphisms 52 biomarker 52 Multivariate analysis 52 deleterious mutations 52 P2X 52 MHC genes 52 mammographic density 52 EAAT2 52 μ opioid receptor 52 polygenic 52 heritable traits 52 transcriptional profiles 52 GPR# [002] 52 molecular pathways 52 colorectal neoplasia 52 extramedullary 52 LRRK2 52 mosaicism 52 homeobox gene 52 chromosome rearrangements 52 Prox1 52 5 methylcytosine 52 epigenetic changes 52 dbSNP 52 phospho 52 V3 loop 52 familial clustering 52 CRISPR 52 TAp# 52 beta globin gene 52 C. pneumoniae 52 CHRNA5 52 MDR1 52 radial glia 52 breast carcinoma 52 LDL receptor 52 X inactivation 52 SRY gene 52 N acetyltransferase 52 subpopulations 52 globin gene 52 phylogenetically 52 morphologically 52 heterologous expression 52 histone demethylase 52 genomic rearrangements 52 receptor ligand 52 dopamine transporter 52 PcG proteins 52 Figure 2C 52 transgene 52 UCRs 52 gp# [002] 52 amino terminal 52 NPM1 mutations 52 GBA mutations 52 genetic lineages 52 Wnt signaling pathway 52 HLA DRB1 * 52 potent inhibition 52 monophyletic 52 phylogenetic 52 eukaryotic cells 52 gene variant 52 IGF 1R 52 chromatin immunoprecipitation ChIP 52 histologic subtypes 52 BRAF mutation 52 apoE4 52 polymerases 52 Aß 52 amino acid substitution 52 CDX2 52 activating mutation 52 APOE genotype 52 miR 52 transcriptional regulators 52 plastid 52 subtype 52 HER3 52 beta catenin 52 miR #b [001] 52 sRNAs 52 WT1 52 telomere length 52 ErbB2 52 transgenic mouse model 52 RNA polymerase II 52 causative gene 52 nucleic acid sequence 52 Arabidopsis genome 52 Plasmodium 52 VKORC1 52 gene APOE 52 YKL 52 HPV# 52 neutralizing antibody 52 TP# mutation 52 variant alleles 52 apolipoprotein E gene 52 KCNQ1 52 HNPCC 52 transposable elements 52 generalized vitiligo 52 pathologic 52 cystatin C 52 HepG2 cells 52 OGG1 52 microRNAs miRNAs 52 metabolomic profiles 52 meiotic 52 lipoxygenase 52 Phylogenetic analysis 52 constitutively 52 hydroxylase 52 ligands 52 carboxyl terminal 52 GBM tumors 52 leptin receptor 52 prognostic markers 52 QTL mapping 52 epigenetic regulation 52 G allele 52 thyroglobulin 52 gene polymorphism 52 genomic instability 51 lysine residues 51 synthases 51 inhibitory receptor 51 etiologic 51 pRb 51 ERK2 51 microglial 51 Methylation 51 SLC#A# [001] 51 V#F mutation 51 prodynorphin 51 HRCT 51 morphologic 51 EGF receptors 51 prion proteins 51 BRCA1 BRCA2 51 subunits 51 Hox gene 51 tropomyosin 51 cytogenetic 51 serotonin receptor 51 IFN gamma 51 disulfide bond 51 MMP# 51 Genetic variations 51 NR#A# gene 51 EZH2 51 UGT#A# * 51 PAX5 51 nicotinic receptor 51 haploid 51 L. pneumophila 51 mitotic spindles 51 immunoreactivity 51 PCR amplified 51 codon usage 51 Pin1 51 monozygotic 51 dizygotic twins 51 P cadherin 51 neoplastic 51 p# [001] 51 S. cerevisiae 51 Skp2 51 coiled coil 51 pseudogene 51 nucleotide substitution 51 C. albicans 51 catenin 51 antigenic 51 RCAN1 51 DNA polymerases 51 lymphoid cells 51 Li Fraumeni syndrome 51 IRAK1 51 unmethylated DNA 51 ApoE 51 TT genotype 51 demethylase 51 Drosha 51 hyperplastic 51 microRNA 51 prion strains 51 c MYC 51 TIMP 1 51 ubiquitin ligase 51 kinase 51 autosomes 51 plastids 51 epigenetic 51 APOL1 51 HER2 expression 51 C. jejuni 51 nucleolin 51 MIF protein 51 Cyclin E 51 genomic sequence 51 outbred 51 PALB2 gene 51 nAChR 51 Cyclin D1 51 SORL1 51 covariates 51 MnSOD 51 GAPDH