Related by context. All words. (Click for frequent words.) 73 adaptive immune 72 mucosal immune 72 innate immune response 72 innate immune responses 71 adaptive immunity 71 humoral immunity 71 intracellular pathogens 70 innate immunity 70 antibody mediated 70 NOD2 69 Fc receptor 69 mucosal immunity 69 bacterial virulence 69 antimicrobial peptides 68 antioxidant enzymes 68 Innate immune 68 innate immune system 67 cyclic adenosine monophosphate cAMP 67 CCL5 67 beta defensins 67 T lymphocyte 67 phagocytosis 67 neurite outgrowth 67 IL 1β 67 FGFs 67 Th# cells 67 RNA silencing 67 p# MAPK 66 autophagic 66 TMEM#B 66 Th2 immune 66 immunological 66 regulating gene expression 66 tumor metastasis 66 TRIM5 66 tetherin 66 intracellular bacteria 66 costimulatory 66 RAS RAF MEK 66 superantigens 65 excitotoxic 65 cholesterol metabolism 65 nitric oxide synthase 65 renal fibrosis 65 serine proteases 65 cAMP signaling 65 metabolic enzymes 65 Th# 65 inflammasome 65 proinflammatory 65 TGFβ 65 pDCs 65 TXNIP 65 cytoprotective 65 neuroendocrine 65 tyrosine phosphorylation 65 HSF1 65 cytokine signaling 65 detoxify carcinogens 65 dendritic cells DCs 65 autoreactive 65 sortilin 65 Smad3 65 virulence genes 65 IKK2 65 NADPH oxidase 65 Innate immunity 65 CD1d 65 MAPKs 65 humoral 65 IFN γ 65 basophils 65 transcriptional regulation 64 chitinase 64 TSLP 64 neuromuscular junction 64 synaptogenesis 64 peroxisome 64 Th1 cells 64 oncogenesis 64 virulence factors 64 γ secretase 64 plasminogen 64 intracellular signaling 64 PAR1 64 antitumor immune 64 Oncogenic 64 NKT cells 64 oncogenic signaling 64 neuronal signaling 64 SCD1 64 commensal bacteria 64 downregulating 64 autoreactive T cells 64 activin 64 Hh pathway 64 pathophysiological 64 granzyme B 64 signaling cascades 64 HCV replication 64 NKT cell 64 TGF ß 64 microvascular endothelial cells 64 neurotrophic 64 apoptotic pathway 64 invading pathogen 64 cellular metabolism 64 TLR signaling 64 NKG2D 64 effector molecules 64 tumorigenesis 64 androgen receptor AR 64 microbial invaders 64 acetylcholine receptor 64 glutamate receptors 64 oncogenic transformation 64 heme oxygenase 64 neuroinflammatory 64 tumor suppressor protein 64 ERK pathway 64 BMP4 64 macrophage 64 Th2 63 genotoxic stress 63 MAPK pathway 63 potent inducer 63 Th1 type 63 alveolar macrophages 63 glycolipids 63 DNA demethylation 63 epigenetic alterations 63 induced neuronal 63 podocytes 63 MAP kinases 63 eNOS 63 c MET 63 IL 1beta 63 Treg cells 63 sphingolipid 63 calcineurin 63 experimental autoimmune encephalomyelitis 63 cathepsins 63 cholesterol homeostasis 63 lipopolysaccharide 63 HPA axis 63 oncogenic 63 hyperactivation 63 interleukins 63 dysregulation 63 TRPV4 63 TRIM# 63 hematopoietic cells 63 T lymphocytes 63 RIP1 63 aT cell 63 pleiotropic 63 CD8 cells 63 synapse formation 63 NFAT 63 p#NTR 63 prostaglandin synthesis 63 EGF receptor 63 LDL receptor 63 GnT 4a 63 C5aR 63 intestinal epithelium 63 excitatory neurotransmitter glutamate 63 neuroinflammation 63 immunological tolerance 63 cytokine 63 C EBP alpha 63 epithelial barrier 63 RUNX3 63 Treg cell 63 Src kinase 63 cytokines 63 microglial 63 phagocytes 63 fatty acid biosynthesis 63 NK cells 63 PTPN# 63 immunological mechanisms 63 invading microbes 63 CCL# 63 retinoid X 63 invading pathogens 63 LRP5 63 serum antibodies 63 eotaxin 63 β catenin 63 Th2 cytokines 63 immune responses 63 cytotoxic T lymphocytes 63 inducible nitric oxide synthase 63 Th1 63 overactivation 63 lymphoid tissues 63 lymphoid organs 63 AT1R 63 arginase 63 proteolysis 63 Pim kinases 63 Cdc7 63 Helicobacter 63 GPx 63 C. albicans 63 heterologous 63 Src kinases 63 membrane receptors 63 podocyte 62 renal tubular 62 neuronal cells 62 Notch receptor 62 Nedd4 62 DNA methyltransferases 62 hypothalamic pituitary adrenal axis 62 neutralizing antibody 62 PPAR γ 62 ectopic expression 62 matrix metalloproteinases 62 Ets2 62 viral antigens 62 neuronal plasticity 62 microbial pathogens 62 neuronal dysfunction 62 pathophysiological effects 62 histone modification 62 ERK signaling 62 glucocorticoid receptor 62 cyclic AMP cAMP 62 adipogenic 62 fatty acid oxidation 62 subcellular compartments 62 interferon γ 62 Akt3 62 leukocyte adhesion 62 transduce 62 macrophage cells 62 non coding RNA 62 serine threonine kinase 62 Nrf2 62 Fc receptors 62 STAT4 62 intracellular 62 PDGFR 62 effector T 62 MT1 MMP 62 NF kappaB 62 phosphatases 62 intestinal microflora 62 FGFR1 62 leptin signaling 62 S6K 62 anthrax toxins 62 p# pathway 62 S#K# 62 AMPA receptor 62 NF κB 62 cytolytic 62 evolutionarily conserved 62 amyloid formation 62 p#Kip# 62 ubiquitination 62 NF kB pathway 62 tissue homeostasis 62 Rap1 62 c Src 62 EZH2 62 effector cells 62 UCP2 62 TGF β 62 p# activation 62 mitogenic 62 oncoprotein 62 CHD7 62 Hedgehog signaling 62 PB1 F2 62 ERK1 2 62 immunopathology 62 Th2 cells 62 NF KappaB 62 mitochondrial fusion 62 enzymatic pathways 62 antioxidant enzyme 62 lipid rafts 62 effector functions 62 synaptic transmission 62 lipid synthesis 62 proinflammatory cytokines 62 apoE 62 cholinergic 62 ENaC 62 Hypoxia Inducible Factor 62 peroxynitrite 62 adult neurogenesis 62 neuronal differentiation 62 ubiquitin ligase 62 anthrax toxin 62 PPAR alpha 62 IKKa 62 allergic inflammation 62 cholesterol efflux 62 intracellular signal transduction 62 haematopoietic 62 Stat1 62 Hsp# [001] 62 MAP kinase pathway 62 immunologic 62 proinflammatory cytokine 62 CD8 T cells 62 proapoptotic 62 biologic pathway 62 Nod1 62 interleukin 1beta 62 phagocytic cells 62 hedgehog pathway 62 epithelial tissues 61 RAS pathway 61 phenotypic expression 61 amyloidogenic 61 tropomyosin 61 Integrins 61 ARF1 61 vascular endothelial cells 61 microglial cells 61 reactive oxygen 61 TLR9 61 stem cell differentiation 61 thioredoxin 61 activated lymphocytes 61 bacterial toxins 61 GABAergic interneurons 61 superoxide dismutase 61 pathogenic mechanisms 61 Wnt pathway 61 neuroligins 61 PI3K pathway 61 P. gingivalis 61 renin angiotensin aldosterone 61 biofilm formation 61 uPAR 61 immunoregulatory 61 abnormal angiogenesis 61 IFN gamma 61 Notch1 61 catabolism 61 viral proteins 61 defensins 61 Hh 61 neutrophil recruitment 61 erythropoiesis 61 CD8 T cell 61 SIRT3 61 ACAT2 61 ryanodine receptor 61 IL 1ß 61 IRAK1 61 serpin 61 RNAi pathway 61 cell signaling pathways 61 CCR9 61 transgene expression 61 glial derived neurotrophic 61 prostaglandin E2 PGE2 61 LPA1 receptor 61 Lyn kinase 61 intestinal mucosa 61 hematopoiesis 61 E3 ubiquitin ligase 61 matrix metalloproteinases MMPs 61 anti inflammatory cytokine 61 iNOS 61 cell motility 61 mitogen activated protein kinase 61 LIS1 61 STAT3 signaling 61 alveolar macrophage 61 genomic instability 61 neuropeptide Y NPY 61 prostaglandin E2 61 Clusterin 61 immune cells 61 upregulating 61 aldose reductase 61 biogenesis 61 effector function 61 COX2 61 regulates gene expression 61 FOXO3a 61 alpha synuclein gene 61 paracrine 61 hematopoietic 61 modulate gene expression 61 EphA2 61 P cadherin 61 selective inhibition 61 STAT1 61 protein conformation 61 posttranslational modification 61 NFκB 61 CTGF 61 Prox1 61 uPA 61 EphB2 61 dopaminergic neurons 61 AhR 61 fibrin deposition 61 Quorum sensing 61 TAp# 61 Cytotoxic T 61 microRNAs miRNAs 61 transgenic rats 61 HBx 61 CPEB 61 oxidative phosphorylation 61 invading microorganisms 61 Galectins 61 TNF α 61 inhibitory 61 #T# L1 61 IMPDH 61 proinflammatory mediators 61 naturally occurring enzyme 61 caveolin 1 61 APOBEC3G 61 Fas ligand 61 cardiolipin 61 EGFR signaling 61 hsp# 61 secrete proteins 61 NLRP3 61 neuropeptides 61 peptide antigens 61 TNFR 61 osteoclast formation 61 p#INK#a 61 protein secretion 61 upregulation 61 Apobec3 61 beta1 integrin 61 messenger molecule 61 glutamatergic 61 PPARg 61 PHD2 61 TLR3 61 deacetylation 61 heme oxygenase 1 61 osteoclast 61 peripheral tissues 61 gastric carcinogenesis 61 Skp2 61 follistatin 61 Notch signaling 61 immunoregulation 61 neurotrophins 61 c myc 61 synuclein 60 elastase 60 neurotransmitter receptors 60 IL #p# 60 stathmin 60 superoxide radicals 60 cellular pathways 60 TGF beta pathway 60 neuronal degeneration 60 phenotypic plasticity 60 inflammatory cascade 60 neurotransmitter GABA 60 epigenetic modifications 60 CYP#B# 60 Mcl 1 60 Genetic variation 60 lung epithelium 60 organogenesis 60 immunized mice 60 FOXO 60 RNA splicing 60 antigenic variation 60 4E BP1 60 POMC neurons 60 upregulate 60 overactivated 60 M1 macrophages 60 γδ T cells 60 Jhdm2a 60 beta adrenergic receptors 60 epigenetic mechanisms 60 humoral responses 60 CYP#A# enzyme 60 immunomodulation 60 costimulation 60 TRIM5 alpha 60 Entamoeba 60 fibrogenesis 60 BMP signaling 60 paxillin 60 ADAMTS# 60 adenylate cyclase 60 motor neuron degeneration 60 epithelial cells lining 60 lymphotoxin 60 PI3 kinase pathway 60 encodes protein 60 mRNA translation 60 cofilin 60 Lymphocytes 60 potent inhibition 60 C5a 60 catenin 60 neutralizing antibody responses 60 ACE2 60 intracellular proteins 60 protein kinase C 60 galectins 60 IRF5 60 CD8 + 60 protease enzyme 60 apoptotic 60 N Myc 60 leukocytes 60 excitotoxicity 60 GLI1 60 chromatin remodeling 60 CXCL# 60 myeloid derived 60 MMP9 60 commensals 60 Abeta peptide 60 CTLs 60 SUMOylation 60 mutant proteins 60 GABAA receptors 60 trophoblast 60 endogenous cannabinoids 60 phosphorylates 60 evolutionarily ancient 60 interferon pathway 60 neuronal cell 60 NFkB 60 lectins 60 activated macrophages 60 oligomerization 60 mutant huntingtin 60 FOXP3 60 aberrantly activated 60 TNFa 60 receptor molecule 60 potent inhibitors 60 TNFalpha 60 CD#L 60 Htt 60 Cathepsin B 60 c MYC 60 p#/CBP 60 vitamin D receptors 60 protein synthesis 60 cyclic AMP 60 pathogenetic 60 synovial cells 60 Dopaminergic 60 anti apoptotic 60 metalloproteinases 60 bone morphogenetic proteins BMPs 60 Foxp3 60 pRb 60 mucociliary clearance 60 insulin signaling pathway 60 CB2 receptor 60 antibody IgE 60 homodimers 60 Hedgehog pathway 60 intestinal microbiota 60 tumor suppressive 60 glucocorticoid receptor GR 60 vascular endothelium 60 Sirt3 60 spermidine 60 C. neoformans 60 PAK1 60 TLE3 60 signaling molecules 60 LXRs 60 neurotransmitter glutamate 60 TrkB 60 bacterial fungal 60 membrane fusion 60 mitochondrial dysfunction 60 TGF b 60 outer membrane proteins 60 IGF IR 60 serine protease 60 tau phosphorylation 60 immunomodulatory effects 60 intracellular signaling pathways 60 Rab5 60 CagA 60 receptor mediated endocytosis 60 viral antigen 60 SH#B# 60 membrane lipids 60 Dietary restriction 60 suppressor cells 60 constitutively expressed 60 Macrophage 60 CD4 + T lymphocytes 60 HIF 1alpha 60 FMRP protein 60 aP2 60 CaM kinase II 60 chemokine receptor 60 bacteria Streptococcus pneumoniae 60 Sirtuins 60 reactive oxygen species ROS 60 LKB1 60 cardiac fibroblasts 60 TGF beta signaling 60 cell adhesion 60 dependent cellular cytotoxicity 60 TGF beta1 60 gut mucosa 60 Sgk1 60 lysosomal 60 Ashwell receptor 60 Wnt signaling 60 leukocyte recruitment 60 kinase pathway 60 endogenous ligands 60 proteases 60 Vpu 60 abzymes 60 transmembrane receptor 60 MAP kinase 60 replicon 60 inflammatory cytokines 60 ischemia reperfusion injury 60 VE cadherin 60 EBV infection 60 Epstein Barr Virus EBV 60 pro angiogenic 60 endogenous retroviruses 60 pancreatic islet 60 upregulates 60 CXCR2 60 protein misfolding 60 PI3K signaling 60 biosynthetic pathways 60 VEGF protein 60 cisplatin resistant 60 insect herbivores 60 JAZ proteins 60 leptin receptor 60 mycobacteria 60 bacterial colonization 60 Wnt signaling pathway 60 PPARγ 60 platelet activation 60 genes encoding 60 oxidative stress 60 FANCD2 60 HbF 60 p# alpha [001] 60 mtDNA mutations 60 mutant huntingtin protein 60 Stat5 60 focal adhesion kinase FAK 60 airway remodeling 60 mRNA decay 60 intercellular communication 60 hepatic stellate cell 60 neural tissue 60 morphogen 60 CPT1c 60 IKKß 60 noncoding RNA 60 neurotransmission 60 cytotoxic T 60 metalloproteinase 60 Androgen receptor 60 SOCS1 60 proton pump 60 Gamma interferon 60 glucocorticoid receptors 60 RANK Ligand 60 astrocytic 60 CD# ligand 60 Bacteroides 60 FasL 59 redox reactions 59 flagellin 59 phagocyte 59 Six3 59 carbohydrate metabolism 59 JAK2 enzyme 59 ErbB receptors 59 MDSCs 59 urease 59 epithelial cell 59 neuro endocrine 59 cholinergic neurons 59 VIPR2 59 muscarinic receptors 59 signaling pathways 59 oncoproteins 59 FGF2 59 multigenic 59 Neuropeptide Y 59 SIRT1 gene 59 signal transduction 59 myogenesis 59 CRISPR Cas 59 downregulation 59 SGK1 59 norepinephrine reuptake inhibition 59 mucosal surfaces 59 cyclophilin D 59 cholecystokinin CCK 59 T. cruzi 59 intracellular pathogen 59 genetic recombination 59 endocannabinoid system 59 proximal tubule 59 CCR7 59 dimerization 59 JAK STAT pathway 59 E#F# 59 SETDB1 59 S#A# [002] 59 protein CETP 59 effector memory 59 proNGF 59 TLR2 59 chromatin structure 59 ADAM# 59 neurofibromin 59 primary cilia 59 ubiquitylation 59 epigenetic inheritance 59 glutamate signaling 59 peroxisomes 59 TSC1 59 vascular endothelial 59 inhibiting enzymes 59 microbiota 59 interleukin 1β 59 epithelia 59 retinal neurons 59 GRP# 59 neutrophil 59 TB bacterium 59 mitochondrial metabolism 59 adipogenesis 59 posttranslational modifications 59 topoisomerase II 59 Angiotensin converting enzyme 59 protein tyrosine phosphatases 59 peroxisomal 59 autocrine 59 Th2 responses 59 diphtheria toxin 59 monocyte 59 axonal damage 59 beta lactamases 59 hypothalamic pituitary 59 receptor CD# 59 Francisella 59 TGF β1 59 Skeletal muscle 59 ABCA1 59 activate p# 59 miR# 59 malonyl CoA 59 GSK3B 59 Smoothened 59 hormone secretion 59 inhibitory neurotransmitters 59 NF kB signaling 59 TRPV3 59 infectious prion proteins 59 Ku# 59 epigenetic silencing 59 mononuclear phagocytes 59 homeostatic 59 inhibit viral replication 59 HIF1 alpha 59 serotonergic 59 Francisella tularensis 59 receptor gamma 59 genes encode proteins 59 biologic pathways 59 XBP1 59 Aβ 59 neural precursor 59 diffusible 59 p# mutations 59 mucins 59 Endocannabinoids 59 KRAS oncogene 59 replicase 59 hedgehog signaling 59 dysregulated 59 EGFR pathway 59 matrix metalloproteinase 59 molecular chaperones 59 retroviral infection 59 immunological responses 59 hepatocyte 59 TRIM5a 59 FGFR2 59 c myc gene 59 Mdm2 59 mitochondrial enzyme 59 COX enzymes 59 CIB1 59 digesting enzymes 59 Oxidative stress 59 TLR8 59 potent stimulator 59 estrogen metabolism 59 PKC alpha 59 ACh 59 TSP1 59 secretory pathway 59 protein tyrosine kinase 59 FUS1 59 hypoxia inducible transcription 59 hyperactivated 59 interleukin IL -# 59 tumor antigens 59 ChR2 59 protein tau 59 transcriptional activation 59 NAD + 59 killer NK 59 lipid metabolism 59 histone deacetylases 59 Akt1 59 effector proteins 59 stem cell pluripotency 59 mitogen activated protein kinases 59 neural tissues 59 molecular mimicry 59 endothelial nitric oxide synthase 59 chemotactic 59 chemokine 59 oxidative damage 59 ERK5 59 molecular determinants 59 quorum sensing 59 intestinal epithelial cells 59 SMN1 59 autophagy 59 Dystrophin 59 D aspartic acid 59 CEACAM1 59 NPD1 59 eukaryotic cells 59 gene p# 59 synthetase 59 β1 59 mitochondrial mutations 59 neutrophils 59 fibrotic disease 59 ciliates 59 adipocyte 59 malarial parasites 59 TRP channels 59 FGFR4 59 kidney urologic 59 ErbB4 59 TRPV1 receptors 59 steroidogenic 59 Robo4 59 midgut 59 mitochondrial respiration 59 isoenzymes 59 TERT 59 motor neuron 59 Aromatase 59 SH2 B 59 HDAC6 59 acetyltransferase 59 somatostatin 59 TCF#L# 59 secrete hormones 59 drug metabolizing enzymes 59 TLRs 59 proteinases 59 Toxoplasma gondii 59 GABAergic 59 cryopyrin 59 cAMP 59 telomere maintenance 59 transcriptional repressor 59 MyD# 59 mRNA degradation 59 TNF receptors 59 oxidized lipids 59 transcriptional regulators 59 NF kappaB activation 59 vesicular stomatitis virus 59 Stress hormones 59 Dysregulation 59 cellular prion protein 59 amyloid beta peptide 59 tubulin polymerization 59 adrenoceptor 59 axon outgrowth 59 tumorigenicity 59 glucocerebroside primarily 59 molecular pathogenesis 59 coagulation cascade 59 gluconeogenesis 59 Nf1 59 Rb#/p# 59 acetylcholinesterase 59 GPR# [002] 59 BRAF protein 59 thymidylate synthase 59 inflammatory cytokine 59 phospholipid membranes 59 TLR4 59 palytoxin 59 mutated protein 59 PIP2 59 Or#b 59 viral genomes 59 autoimmunity 59 Wnts 59 cytokine secretion 59 antigen receptor 59 calpain 59 miR #a [001] 59 super oxide dismutase 59 inverse agonist 59 integrins 59 endogenous opioid 59 E1A 59 nAChR 59 multiprotein complex 59 mitochondrial function 59 nitric oxide synthase NOS 59 resolvins 59 Upregulation 59 pertussis toxin 59 Bt toxins 59 Nurr1 59 estrogen receptor alpha 59 AT1 receptor 59 tenascin C 59 PIP3 59 siRNA mediated 59 carcinogenesis 59 cypin 59 epigenetic regulation 59 intercellular signaling 59 atherogenesis 59 non mammalian vertebrates 58 sensory neuron 58 microtubule dynamics 58 naturally occurring molecule 58 SIRT6 58 homologous recombination 58 pancreatic endocrine 58 pathogen interactions 58 granuloma formation 58 herpesviruses 58 polyamines 58 Angiotensin II 58 isotypes 58 p# MAP kinase 58 AMP kinase 58 Sonic Hedgehog 58 antiapoptotic 58 RNA polymerases 58 incretin 58 tumor microenvironment 58 mesenchymal cell 58 Notch signaling pathway 58 eicosanoids 58 RNase L 58 aryl hydrocarbon receptor 58 Aldosterone 58 kappa opioid receptor 58 major histocompatibility complex 58 F actin 58 IRS1 58 methyl D aspartate 58 systemic inflammation 58 inducible 58 Rac1 58 epigenetically 58 tuberculosis bacterium 58 osmotic stress 58 Wnt1 58 tumor angiogenesis 58 NMDA receptors 58 enzymatic activity 58 Eg5 58 neural crest