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(Click for frequent words.) 72 inhibition 71 excitatory 71 NMDA receptors 71 glutamate receptors 69 cAMP 69 glutamate 69 NMDA receptor 69 D2 receptor 69 serotonergic 69 AMPA receptor 68 ERK1 2 68 dopaminergic 68 mitogen activated protein kinase 68 IL 1β 68 muscarinic receptors 68 HPA axis 68 p# MAPK 68 paracrine 68 inducible 68 cyclic AMP 68 striatal 68 glucocorticoid receptor 68 glucocorticoid 68 glutamatergic 68 microglial 68 MAPK 68 eNOS 68 GABAergic 67 dopamine receptors 67 serotonin transporter 67 serotonin receptor 67 TGF β 67 signaling pathways 67 CEACAM1 67 beta catenin 67 p# activation 67 beta adrenergic receptors 67 protein kinase 67 PGE2 67 circadian clock genes 67 BDNF 67 microglial activation 67 Aβ 67 intracellular 67 noradrenergic 67 neurite outgrowth 67 β catenin 67 MAP kinase 67 PDGFR 67 PPAR gamma 67 TrkB 67 mRNA expression 66 opioid receptor 66 dopamine receptor 66 TGF ß 66 acetylcholine 66 neuronal 66 MEF2 66 sensory neurons 66 GABA receptors 66 Wnt signaling 66 IL 1beta 66 BMP signaling 66 receptors 66 inhibitory effect 66 hypothalamic pituitary adrenal axis 66 Th2 66 autocrine 66 Cdc# 66 noradrenaline 66 ENaC 66 synaptic transmission 66 cyclins 66 adhesion molecule 66 synaptic plasticity 66 autophagic 66 overexpressing 66 endogenous 66 IFN gamma 66 Hh 66 calpain 66 nicotinic receptors 66 nAChR 66 SIRT1 gene 66 pDCs 66 ACh 66 FasL 66 Notch1 66 overactivation 66 IFN γ 65 intracellular signaling 65 receptor 65 paxillin 65 mitogenic 65 beta endorphin 65 IKKß 65 STAT1 65 protein kinase C 65 somatostatin 65 D2 receptors 65 SUMOylation 65 acetylcholine receptor 65 Skp2 65 TNFalpha 65 neurotrophin 65 pRb 65 neuronal differentiation 65 TGFβ 65 neurotransmitter 65 SOCS3 65 FAK 65 proapoptotic 65 signaling pathway 65 downregulate 65 signaling molecule 65 synapse formation 65 mTOR 65 CB1 receptors 65 synaptogenesis 65 phosphorylation 65 Nrf2 65 catenin 65 apoptotic 65 hypothalamic 65 tyrosine phosphorylation 65 E#F# 65 downregulation 65 NR2B subunit 65 neurons 65 iNOS 65 NKT cell 65 pro angiogenic 65 TRPV3 65 receptor activation 65 tumor suppressive 65 VEGF receptor 65 EGF receptor 65 catecholamine 65 E cadherin 65 calcineurin 65 FOXO 65 proteolysis 65 neuropeptide 65 glutamate receptor 64 proinflammatory 64 inflammatory cytokine 64 dopamine 64 ErbB2 64 mTOR signaling 64 phosphatases 64 beta arrestin 64 cholinergic 64 chromatin remodeling 64 antiapoptotic 64 aromatase 64 amyloid β 64 Akt 64 excitatory synapses 64 FGFs 64 adrenergic receptors 64 Th1 64 transcription factors 64 acetylcholine receptors 64 neurotrophic 64 cofilin 64 HDAC2 64 cytokine 64 SIRT1 64 N methyl 64 IL 1ß 64 secretion 64 lysosomal 64 cyclooxygenase 64 dopamine signaling 64 serotonin receptors 64 CXCL# 64 FKBP# 64 proteolytic 64 excitatory neurotransmitter 64 RANKL 64 5 HT1A 64 phagocytosis 64 AMPA receptors 64 glucocorticoid receptors 64 opioid receptors 64 AT1R 64 MEK1 64 NKT cells 64 chemokine 64 mitochondrial respiration 64 neuromuscular junction 64 synaptic 64 nociceptive 64 GABAergic neurons 64 neurotransmitter GABA 64 CatB 64 overexpression 64 ERK signaling 64 TAp# 64 tyrosine kinases 64 p#NTR 64 Foxp3 64 UCP2 64 inhibitory neurotransmitters 64 uPAR 64 PTP1B 64 receptor subtypes 64 presynaptic 64 neuropeptides 64 Aß 64 Rac1 64 endocannabinoid system 64 sortilin 64 immunoreactivity 64 oncogenic 64 GRK2 63 MeCP2 63 receptor subtype 63 TSLP 63 monocyte 63 ATPase 63 #HT#A 63 TNF α 63 MAPK pathway 63 c myc 63 isoenzymes 63 neurotransmission 63 Hcrt 63 hedgehog pathway 63 deacetylation 63 ERK pathway 63 S#K# 63 anti apoptotic 63 retinoic acid 63 pro inflammatory cytokines 63 neuronal signaling 63 basal ganglia 63 TGF beta 63 inhibitory receptor 63 selective inhibition 63 mitochondrial enzyme 63 neurones 63 ERK2 63 cannabinoid receptors 63 kinase pathway 63 TRPV1 receptors 63 receptor tyrosine kinase 63 nAChRs 63 transactivation 63 cytokine signaling 63 p#Kip# 63 metabolic enzymes 63 inflammatory cytokines 63 NADPH oxidase 63 NF kB pathway 63 Wnt 63 c MYC 63 dopaminergic neurons 63 TLR4 63 PI3 kinase 63 Kv#.# 63 dopamine transporter 63 p# [001] 63 inhibitory effects 63 homeostatic 63 axonal 63 CB1 receptor 63 contractility 63 neurotransmitter glutamate 63 estrogen receptor alpha 63 upregulating 63 estrogen receptor beta 63 PPAR alpha 63 cadherin 63 Wnt pathway 63 caveolin 1 63 S6K 63 proinflammatory cytokine 63 GPR# [002] 63 costimulatory 63 constitutively active 63 SIRT3 63 neurogenesis 63 neuronal dysfunction 63 serotonin 63 XBP1 63 beta subunit 63 connexin# 63 HBx 63 BMP4 63 cyclin E 63 RhoA 63 ABCA1 63 thioredoxin 63 oligomerization 63 androgen receptor 63 transmembrane protein 63 glutamate signaling 63 vascular endothelial cells 63 ubiquitylation 63 NF kappaB activation 63 mu opioid receptors 63 GluR1 63 KLF4 63 MDSCs 63 miR# 63 neuronal plasticity 63 5 HT2A receptor 63 hippocampal neurons 63 cyclooxygenase 2 63 HDACs 63 Hedgehog signaling 63 extracellular 63 casein kinase 63 hyperactivation 63 EphA2 63 extracellular signal 63 PPARg 63 postsynaptic 63 NR2B 63 demethylation 63 renal fibrosis 63 adipocyte 63 SIRT2 63 motoneurons 63 Smad3 63 ß catenin 63 interneurons 63 astrocytic 63 NF kappaB 63 suppressor cells 63 Notch pathway 63 nicotinic 63 nicotinamide 63 S#A# [002] 63 glial 63 neurosteroid 63 adenosine receptor 63 progranulin 63 cyclic AMP cAMP 63 mTORC1 63 IKK2 63 Notch signaling 63 NF κB 63 morphogen 63 vWF 63 activin 63 STAT3 62 c Src 62 brain derived neurotrophic 62 Rab5 62 eotaxin 62 tumorigenesis 62 astrocyte 62 antioxidant enzymes 62 NF kB 62 catabolism 62 potent inhibitors 62 neurotransmitter dopamine 62 cannabinoid receptor 62 PI3K Akt 62 ubiquitination 62 cyclin D1 62 transcriptional repressor 62 HDAC 62 mPFC 62 dysregulated 62 signaling molecules 62 habenula 62 HepG2 cells 62 MnSOD 62 Lyn kinase 62 S1P 62 TNFa 62 effector memory 62 adenylate cyclase 62 ubiquitin ligase 62 P cadherin 62 neurofilament 62 IL #p# 62 neurotransmitters 62 anterior cingulate 62 neuronal excitability 62 #ß 62 upregulation 62 cytoprotective 62 acetylation 62 osteoblast 62 neuron 62 Treg cells 62 FGF2 62 kinase domain 62 PPARγ 62 PPARgamma 62 act synergistically 62 nicotinic receptor 62 D aspartate 62 TrkA 62 SGK1 62 proto oncogene 62 cingulate 62 endocannabinoids 62 cytoskeletal 62 neuropeptide Y 62 MT1 MMP 62 enzymatic activity 62 GSK 3ß 62 TGF beta1 62 Abeta 62 adrenergic 62 MDM2 62 integrins 62 ASIC1a 62 leptin receptor 62 GABAergic interneurons 62 LRP6 62 isoforms 62 effector cells 62 TGF ß1 62 phosphorylate 62 H#K# [002] 62 ERa 62 serotonin reuptake 62 Stat3 62 striatal dopamine 62 inhibitory neurotransmitter 62 neurotransmitters serotonin 62 H#K#me# 62 PKC isoforms 62 MMPs 62 c Myc 62 miR #a [002] 62 Phosphorylation 62 KLF# 62 granule cells 62 intracellular calcium 62 malonyl CoA 62 adrenoceptor 62 antiangiogenic 62 neuroinflammatory 62 cAMP signaling 62 proinflammatory cytokines 62 oncoprotein 62 exocytosis 62 Cx# [001] 62 modulatory 62 neurotransmitter receptors 62 endocytic 62 humoral 62 Hedgehog pathway 62 tumor suppressor protein 62 vasopressin 62 histone acetylation 62 apoE 62 vimentin 62 neuropeptide Y NPY 62 glucokinase 62 CaMKII 62 MyD# 62 oxidase 62 D aspartic acid 62 arginase 62 NF kappa B 62 4E BP1 62 FGF# 62 tyrosine hydroxylase 62 alpha synuclein 62 Bcl xL 62 NFAT 62 androgen receptor AR 62 MyoD 62 neuroendocrine 62 dentate gyrus 62 midbrain 62 aberrantly activated 62 PC# cells 62 TNFα 62 focal adhesions 62 TGF b 62 histone deacetylases 62 Akt signaling 62 Sirt1 62 proteases 62 claudin 62 astrocytes 62 interleukins 62 Jhdm2a 62 basolateral 62 E3 ligase 62 cytokines 62 Src 62 IGFBP2 62 gut mucosa 62 interleukin 1beta 62 PAK1 62 CCR2 62 overactivity 62 Purkinje cells 62 PKM2 61 GSK3 61 NKG2D 61 transcriptional activation 61 CD1d 61 Nampt 61 calcium homeostasis 61 immunomodulatory effects 61 PHD2 61 NAD + 61 TMEM#B 61 tubulin 61 Ca2 + 61 T lymphocyte 61 PTPN# 61 lateral hypothalamus 61 caspases 61 HOTAIR 61 monoamine 61 endothelial nitric oxide synthase 61 cortical neurons 61 MDMX 61 Androgen receptor 61 Dpp 61 mutant huntingtin protein 61 miR #b [001] 61 HDAC6 61 61 IGFBP 3 61 receptor signaling 61 plasminogen 61 orexin receptors 61 induced apoptosis 61 POMC neurons 61 peroxisome proliferator activated 61 genes encoding 61 allergic inflammation 61 phosphorylates 61 endogenous cannabinoids 61 NFkB 61 c MET 61 HCV replication 61 cellular pathways 61 CTGF 61 mPGES 1 61 methyl D aspartate 61 evolutionarily conserved 61 BMAL1 61 gamma secretase 61 phosphorylated 61 neuronal activity 61 dephosphorylation 61 estrogen receptors 61 basal forebrain 61 GABAA receptors 61 inhibitory interneurons 61 WT1 61 opiate receptors 61 incretin 61 utrophin 61 ouabain 61 synapse maturation 61 mu opioid 61 Sgk1 61 osteocalcin 61 GABA receptor 61 mediated inhibition 61 constitutively 61 EZH2 61 cytosolic 61 secreted protein 61 T lymphocytes 61 HIF 1a 61 NAc 61 NMDAR 61 adaptive immunity 61 proteoglycan 61 c fos 61 CCL# 61 GTPase 61 tyrosine 61 tyrosine kinase 61 siRNA mediated 61 E3 ubiquitin ligase 61 adenosine receptors 61 messenger molecule 61 Purkinje cell 61 neurotransmitter receptor 61 survivin 61 TGFbeta 61 Brain derived neurotrophic 61 elastase 61 prostaglandin E2 PGE2 61 induce apoptosis 61 ChR2 61 secretory 61 ER alpha 61 serine protease 61 Notch receptor 61 P glycoprotein 61 inhibitory neurons 61 caveolin 61 receptor gamma 61 inhibitory synapses 61 mice lacking 61 histone 61 chemotactic 61 GAPDH 61 adult neurogenesis 61 tumor suppressor genes 61 opioid peptides 61 glucose transporter 61 NF kappaB pathway 61 JNK1 61 inhibitory activity 61 EGFR signaling 61 enkephalins 61 innate immune 61 TGF beta pathway 61 ErbB4 61 transgene expression 61 syntaxin 61 mesolimbic 61 AMPK 61 micro RNAs 61 neurotrophins 61 IGF 1R 61 Th1 type 61 B7 H1 61 serine proteases 61 endogenous opioids 61 endocannabinoid 61 signaling cascade 61 norepinephrine 61 γδ T cells 61 chemokine receptor 61 NKX#.# 61 signaling cascades 61 excitotoxic 61 Flt3 61 enzyme 61 serine threonine kinase 61 secretory pathway 61 alpha MSH 61 miR 61 thyroid hormone receptor 61 molecular pathways 61 acid GABA 61 neurone 61 HIF 1alpha 61 calmodulin 61 osteoclast formation 61 inhibitory transmitter 61 pro apoptotic 61 agonism 61 tumor microenvironment 61 proteins 61 receptor mediated 61 oxidative phosphorylation 61 Rho GTPase 61 hypothalamic pituitary 61 Th1 cells 61 Bcl 61 potentiation 61 neuronal cells 61 TGFß 61 androgen receptors 61 protein tyrosine kinase 61 virulence genes 60 phosphoinositide 60 gastrointestinal motility 60 corticosterone 60 podocytes 60 tumor suppressor 60 GABAB receptors 60 CaM 60 Smoothened 60 dorsolateral prefrontal cortex 60 glycosyltransferase 60 superoxide dismutase 60 insulin secretion 60 potent inhibition 60 lymphocyte activation 60 dehydrogenase 60 TRPV1 60 nitric oxide synthase 60 dorsal horn 60 TGF beta signaling 60 EGFr 60 SOCS1 60 PI3K 60 polyamine 60 antioxidant enzyme 60 effector T 60 gamma oscillations 60 innate immune responses 60 CYP#B# 60 N cadherin 60 heterodimers 60 enkephalin 60 inverse agonist 60 lymphotoxin 60 melatonin receptors 60 gene encoding 60 cortical 60 angiotensin II 60 reuptake 60 c Fos 60 mutant huntingtin 60 ERK activation 60 c Abl 60 prostaglandin synthesis 60 Mcl 1 60 upregulates 60 costimulation 60 miR #a [001] 60 secretase 60 LDL receptor 60 hypothalamic pituitary adrenal HPA 60 PIP3 60 tumor vasculature 60 dopamine D1 60 Inhibitory 60 innate immunity 60 Runx2 60 apoE4 60 thymic 60 phenotypes 60 muscarinic receptor 60 lipopolysaccharide 60 neuroinflammation 60 MMP9 60 anti inflammatory cytokine 60 neuronal apoptosis 60 netrin 1 60 mRNA translation 60 endothelial 60 bradykinin 60 PDGF receptor 60 aldehyde dehydrogenase 60 hormone secretion 60 antibody mediated 60 Abl 60 phosphatase 60 cyclin 60 NKCC1 60 DISC1 60 pharmacologically 60 somatosensory 60 antitumor 60 Hh pathway 60 p# pathway 60 serotonin neurons 60 immunostimulatory 60 Dysregulation 60 SCD1 60 VEGFR1 60 HbF 60 neuregulin 60 ß 60 NF KappaB 60 transduction 60 signal transduction 60 coexpression 60 occludin 60 nerve cells 60 protein tyrosine phosphatases 60 G9a 60 P#X# receptors 60 oncogenic transformation 60 neural 60 dopamine D2 receptors 60 FoxO1 60 DARPP 60 NFkappaB 60 receptor gene 60 cytokine interleukin 60 STAT4 60 biosynthesis 60 leptin signaling 60 vascular endothelial 60 genotoxic stress 60 insulin receptors 60 Htt 60 Wnt proteins 60 afferent 60 muscarinic 60 TRP channels 60 BCL2 60 PDE1 60 CDKs 60 overactivated 60 EphB2 60 anterior pituitary 60 tyrosinase 60 serpin 60 transcriptional 60 CD8 + T 60 estrogen receptor 60 beta amyloid peptide 60 F actin 60 upregulate 60 palytoxin 60 adipogenic 60 cardiac myocytes 60 osteoclast activity 60 Wnt#b 60 efferent 60 nNOS 60 Akt1 60 PI3K pathway 60 mediated apoptosis 60 PAR1 60 membrane protein 60 allosteric 60 hepatic glucose production 60 prostaglandin E 60 Cdk5 60 β cells 60 metabolizing enzymes 60 eIF4E 60 SH2 B 60 serine threonine 60 paraventricular nucleus 60 adenosine diphosphate ADP 60 LPS induced 60 glomerular 60 FOXO3a 60 neurotransmitter serotonin 60 Th2 immune 60 Th2 cytokines 60 phagocytes 60 gene expression 60 hsp# 60 cytochrome P# 60 TGF β1 60 downregulated 60 melanocyte 60 lysophosphatidic acid 60 β 60 c Myb 60 Rap1 60 cofactor 60 constitutively expressed 60 CHD5 60 urocortin 60 γ secretase 60 cell adhesion molecule 60 adrenocortical 60 fatty acid synthesis 60 agonist induced 60 BACE1 60 gamma amino butyric 60 LKB1 60 Myc 60 beta adrenergic 60 ceramide 60 cyclin B1 60 IFNg 60 Fc receptor 60 innate immune response 60 VEGF 60 EP1 receptor 60 neurotrophic factors 60 PDE5A 60 RNAi pathway 60 neurochemical 60 tyrosine residues 60 neurotransmitter acetylcholine 60 palmitoylation 60 FGFR1 60 alpha secretase 60 excitatory neurotransmitter glutamate 60 Hsp# [001] 60 TRPV4 60 kinase 60 M1 muscarinic 60 immunological 60 neuronal cell 60 JAK STAT signaling 60 transcriptional regulation 60 integrin 60 EGFR pathway 60 cerebellar 60 NFκB 59 fatty acid oxidation 59 mitochondrial 59 IFN alpha 59 TORC1 59 angiogenic 59 PIP2 59 TH1 59 microglial cells 59 COX2 59 NPD1 59 MAP kinases 59 PU.1 59 partial agonist 59 neurite 59 metalloproteinases 59 CYP#E# 59 hippocampal 59 GH secretion 59 dimerization 59 p# alpha [001] 59 CD8 + 59 airway remodeling 59 HERV 59 RUNX3 59 protein p# 59 axon outgrowth 59 prostaglandin E2 59 raphe 59 Akt activation 59 selectively inhibits 59 actin cytoskeleton 59 inflammatory mediators 59 5 lipoxygenase 59 myo inositol 59 E1A 59 mRNAs 59 Aâ 59 cyclin dependent kinase 59 cell signaling pathway 59 bile acid 59 galanin 59 RIP1 59 Oncogenic 59 neutralizing antibody 59 drug metabolizing enzymes 59 transcription factor 59 repressor 59 cytokine secretion 59 EGFR protein 59 MEK ERK 59 Pin1 59 GLI1 59 semaphorin 59 phosphatidylinositol 3 59 nicotinic acetylcholine receptor 59 Vps# 59 ubiquitin ligases 59 PPAR γ 59 molecular pathway 59 ligand TRAIL 59 phenotype 59 TORC2 59 posterior cingulate 59 allopregnanolone 59 mutant proteins 59 Cytotoxic T 59 hypermethylation 59 aldosterone 59 epigenetic silencing 59 myeloid derived 59 glial cell 59 CD8 T cell 59 FGFR4 59 Vpr 59 gamma aminobutyric acid GABA 59 granzyme B 59 acetylcholinesterase 59 synaptic vesicles 59 cathepsins 59 cyclic GMP 59 GABAA receptor 59 CTLA 4 59 BCL#A 59 kappa opioid receptor 59 locomotor activity 59 epigenetic alterations 59 ligases 59 adrenal cortex 59 adhesion molecules 59 dendritic spines 59 HER2 receptors 59 ERBB2 59 TNF receptors 59 ß1 59 cathepsin B 59 CaM kinase II 59 mutated protein 59 neural pathway 59 TTR gene 59 cellular metabolism 59 TLR2 59 hindbrain 59 myocytes 59 cyclic nucleotide 59 leukemic cell 59 leukocyte recruitment 59 enterocytes 59 glycolipids 59 miR #b [002] 59 serotonergic neurons 59 nicotinic acetylcholine receptors 59 LIS1 59 Wnt1 59 transferase 59 Immunohistochemical analysis 59 huntingtin protein