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(Click for frequent words.) 78 ERK1 2 78 serine threonine 78 TNFalpha 77 mTOR mammalian target 77 thrombin receptor 77 extracellular signal 77 cell adhesion molecule 76 Hypoxia Inducible Factor 76 selective inhibition 76 pathophysiological effects 76 regulated kinase 76 VEGF receptor 76 Janus kinase 76 mitogen activated protein kinase 75 Upregulation 75 proto oncogene 75 Phosphorylation 75 phosphatidylinositol 3 75 HIF 1alpha 75 Factor Receptor 75 poly ADP ribose polymerase 74 sodium glucose cotransporter 74 protein tyrosine phosphatase 1B 74 vesicular monoamine transporter 74 chemokine receptor 74 serine protease 74 elastase 74 Protein Kinase C 74 Factor VEGF 74 receptor subtype 74 orally administered inhibitor 74 apoptotic pathway 74 catenin 74 phosphorylates 74 Overexpression 74 Tumor necrosis factor 74 JAK2 enzyme 74 c MET 74 MAP kinase 74 HER1 74 Clusterin 74 PDGFR 73 thrombospondin 73 selective modulator 73 cyclin dependent kinase inhibitor 73 Interferon gamma 73 antiapoptotic 73 colony stimulating factor 73 inducible nitric oxide synthase 73 p# mitogen activated 73 cyclin dependent kinase 73 HIF 1a 73 metalloproteinase 73 ERK pathway 73 induces apoptosis 73 HIF biology 73 isoenzyme 73 androgen receptor AR 73 peroxisome proliferator activated 73 5 lipoxygenase 73 tyrosine kinase 73 LRP6 73 IL 1β 73 homodimers 73 aberrantly activated 73 TNF α 73 soluble tumor necrosis 73 Macrophage 73 activin 73 FGFR3 73 IAP inhibitor 73 pro angiogenic 73 vWF 73 Nedd4 72 regulated kinase ERK 72 Oncogenic 72 hydroxylase 72 FGFR 72 Pathway Inhibitor 72 phosphate S1P 72 adhesion molecule 72 cystic fibrosis transmembrane conductance 72 5 HT2A serotonin 72 ENaC 72 cyclin dependent kinases 72 β catenin 72 Galectin 72 retinoic acid receptor 72 eNOS 72 proapoptotic 72 SIRT2 72 IL6 72 kinase PI3K 72 reductase 72 HIF 1α 72 CXCL# 72 interleukin IL 72 IL 1beta 72 CYP#A# CYP#D# 72 proteoglycan 72 antisense oligonucleotide 72 matrix metalloproteinase 72 cytokines IL 72 urate oxidase 72 serine threonine kinase 72 casein kinase 72 transcriptional repressor 72 protein phosphatase 72 factor HGF 72 Endothelin 72 cyclooxygenase COX 72 1α 72 V#F mutation 72 1alpha 72 N methyl 72 Tie2 72 Tumor Necrosis Factor 72 myelofibrosis polycythemia vera 71 neurofibromin 71 MEK1 71 PTP 1B 71 IL 1ß 71 VEGFR1 71 FLT3 71 effector function 71 c MYC 71 CDK inhibitor 71 selective inhibitor 71 STAT1 71 LRP5 71 interleukin IL -# 71 lysosomal 71 deacetylation 71 JAK1 71 ß catenin 71 acyl CoA 71 acyltransferase 71 FGFR1 71 4E BP1 71 UCP2 71 selective agonist 71 kinase pathway 71 humanized anti 71 Fas ligand 71 Aurora kinase 71 monocyte chemotactic protein 71 immune modulator 71 ERalpha 71 heme oxygenase 71 mediated apoptosis 71 histone deacetylase 71 FasL 71 cyclooxygenase 71 pan HDAC inhibitor 71 molecule epidermal 71 tyrosine phosphorylation 71 pDC 71 peptidic compound 71 lipoxygenase 71 MMP2 71 naturally occurring molecule 71 phosphoinositide 71 thymidylate synthase TS 71 related apoptosis inducing 71 adipogenic 71 receptor tyrosine kinase 71 glycogen synthase kinase 71 interleukin IL -6 71 miR #a [002] 71 selectively inhibited 71 5 hydroxytryptamine 71 cytokine signaling 71 CTLA 4 71 PDGF receptor 71 MEK ERK 71 ERK signaling 70 RAS RAF MEK 70 MEK inhibitor 70 PI3 kinase 70 oncoprotein 70 small molecule inhibitor 70 NFkB 70 PEGylated anti 70 somatostatin 70 adrenoceptor 70 Aurora Kinase 70 EGFR HER2 70 small molecule activator 70 MTP inhibitor 70 EGFr 70 Rap1 70 SGLT2 70 EGF receptor 70 methyl D aspartate 70 humanized monoclonal 70 COX2 70 peroxisomal 70 inverse agonist 70 IL #p# 70 glucocorticoid receptor 70 endothelial nitric oxide synthase 70 PI3K Akt 70 mitogen activated protein kinases 70 transmembrane protein 70 Janus Kinase 70 prolyl 70 prostanoid 70 vascular endothelial 70 downregulates 70 glyceraldehyde 3 70 erythropoiesis 70 Signaling Pathway 70 CYT# potent vascular disrupting 70 intercellular adhesion molecule 70 Caveolin 1 70 selective antagonist 70 transient receptor 70 TRAIL induced apoptosis 70 myeloid derived 70 anti inflammatory cytokine 70 autophagic 70 Fibroblast Growth Factor Receptor 70 calpain 70 HDAC 70 Rab5 70 TMEM#B 70 nicotinic acetylcholine receptor 70 GSTP1 70 decarboxylase 70 Epithelial 70 TNFa 70 colorectal carcinoma 70 IGF1R 70 acetylcholine receptor 70 potent inhibitor 70 TORC2 70 AT1R 70 glucose transporter 70 NFAT 70 5alpha reductase 70 Enzastaurin 70 pro inflammatory cytokine 70 Platelet Derived Growth 70 upregulating 70 upregulates 70 Selective Inhibitor 70 LDL receptor 70 TRAIL R2 70 monocytic 70 HDACi 70 uricase 70 lymphangiogenesis 70 receptors PPARs 70 iNOS 70 E#F# 70 caveolin 1 70 murine model 70 immunoregulatory 70 cytokine receptor 70 M1 muscarinic 70 adipokine 70 Hedgehog signaling 70 JAK2 70 tyrosine kinase receptor 70 CTGF 70 partial agonist 70 sphingosine 1 70 reversible inhibitor 70 ligand TRAIL 70 selectively inhibit 70 superoxide dismutase 70 selectively inhibits 69 ErbB1 69 cyclooxygenase 2 69 thyroid hormone receptor 69 phosphorylated tau 69 ErbB 69 IFN γ 69 osteoblast 69 cytoprotective 69 potential vanilloid 69 eIF4E 69 prostaglandin synthesis 69 TGF β1 69 Flt3 69 CD#b 69 immunostimulatory 69 HepG2 cells 69 AEG# 69 chemokine 69 receptor mediated endocytosis 69 WT1 69 Vascular endothelial growth 69 adenylate cyclase 69 Recombinant Human 69 5 HT4 69 phosphoinositide 3 69 XL# inhibits 69 PKC# 69 receptor inhibitor 69 polycystin 69 Angiotensin converting enzyme 69 interleukins 69 downregulation 69 TGF ß 69 prostaglandin E 69 interferon γ 69 protein tyrosine kinase 69 prostaglandin E2 PGE2 69 transcriptional activation 69 survivin 69 TIMP 1 69 plasmacytoid dendritic cells 69 NFκB 69 histone deacetylase inhibitor 69 PC# cells 69 Akt activation 69 TRAIL receptor 69 Src 69 69 IFN g 69 plasminogen activator inhibitor 69 chemokine receptors 69 1beta 69 MMP9 69 IL #E 69 fibrogenesis 69 bone morphogenetic protein 69 integrin alpha 69 p# alpha [001] 69 PPARg 69 IL #R 69 receptor kinase 69 phosphorylate 69 Mcl 1 69 gastric carcinogenesis 69 receptor monoclonal antibody 69 acetylcholinesterase 69 FOXO3a 69 PEGylated Fab fragment 69 Cyclin E 69 glutathione peroxidase 69 avidin 69 receptor alpha 69 eotaxin 69 Angiotensin II 69 LPS induced 69 Chemokine Receptor 69 Th2 cytokines 69 matrix metalloproteinases MMPs 69 Cytochrome P# 69 caveolin 69 Aldosterone 69 NF kB pathway 69 CCR9 69 Cathepsin B 69 TNF Tumor Necrosis Factor 69 thromboxane A2 69 mediated phosphorylation 69 mitogen activated protein 69 MAPK 69 microglial activation 69 highly selective inhibitor 69 targetters 69 serine proteases 69 HDAC2 69 familial amyloidotic polyneuropathy FAP 69 Notch receptor 69 protein kinase C 69 Epidermal Growth Factor 69 tumor antigen 69 anaphase promoting complex 69 carcinoembryonic antigen 69 keratinocyte 69 cyclic adenosine monophosphate cAMP 69 Smad3 69 Th1 type 69 NKG2D 69 LPA1 69 muscarinic 69 gamma secretase inhibitor 69 topoisomerase II inhibitor 69 calcium calmodulin dependent 69 CD#L 69 metalloprotease 69 TGF alpha 69 Adrenergic 69 Angiotensin 69 histone deacetylases 69 Polymorphisms 69 p# MAPK 69 MET VEGFR2 69 NF kappaB activation 69 aspartyl 69 BCR ABL 69 Secretase 69 peptibody 69 potently inhibit 69 pyrimidines 69 cyclic AMP cAMP 69 methionine aminopeptidase 69 Smad7 69 cytidine 69 TNF receptors 69 peroxidase 69 mediated inhibition 69 EGFR signaling 69 Glucocorticoid 69 Wnt signaling pathway 69 downstream effector 69 potently inhibited 69 Huntingtin 69 glucagon receptor 69 Epidermal Growth Factor Receptor 69 p# MAP kinase 69 VEGF receptors 69 triphosphate 69 LNCaP cells 69 tumor suppressor protein 69 c myc 69 receptor partial agonist 69 constitutively active 69 induced apoptosis 69 Cytotoxic T 69 calcitonin gene related 69 IGFBP 69 investigational humanized monoclonal antibody 69 #beta HSD1 69 guanosine 69 deacetylase 69 BMP2 69 polymerase inhibitor 69 constitutively activated 69 Autoantibodies 69 bone morphogenic protein 69 phospholipase A2 69 Protein Kinase 68 E cadherin expression 68 potent inhibitors 68 apoptosis proteins 68 RANK ligand 68 IGF IR 68 Androgen Receptor 68 novel VDA molecule 68 nAChRs 68 gonadotropin releasing hormone GnRH 68 Proteasome 68 lyase 68 PPARgamma 68 P#X# 68 Rho GTPase 68 transthyretin TTR 68 osteoprotegerin 68 HER3 68 Smoothened 68 Receptor Agonist 68 TNF alpha selectively neutralizing 68 multikinase inhibitor 68 FGF receptor 68 Î ² 68 orally bioavailable mimics 68 TGF Beta 68 Epstein Barr Virus EBV 68 cAMP signaling 68 pRb 68 Tyrosine Kinase Inhibitor 68 angiopoietin 68 E selectin 68 phosphoprotein 68 BMP4 68 kidney urologic 68 C5aR 68 oxidase 68 Omacetaxine 68 telomerase reverse transcriptase 68 alpha folate receptor 68 VE cadherin 68 adipogenesis 68 HCV protease 68 Kinase 68 constitutively expressed 68 bFGF 68 Akt signaling 68 Histone 68 pyrimidine 68 PPAR gamma 68 TGF b 68 Histone Deacetylase 68 c myc gene 68 estrogen receptor beta 68 NF kappa B 68 N acetylgalactosamine 6 68 polyamine 68 mRNA expression 68 beta amyloid peptide 68 PKC beta 68 ERK phosphorylation 68 Dendritic Cells 68 dopamine D2 68 cyclin dependent kinases CDKs 68 immunotoxin 68 heme oxygenase 1 68 SGLT1 68 alpha TNFa 68 uPAR 68 adipocyte 68 ALN TTR 68 B lymphocyte stimulator 68 inhibitory effects 68 secretory pathway 68 cytotoxic T lymphocyte 68 voltage gated 68 RIP1 68 monocytes macrophages 68 lysophosphatidic acid 68 RANK Ligand 68 FGF2 68 stem cell pluripotency 68 targeted antifolate 68 S1P 68 PNP inhibitor 68 PTHrP 68 selectively binds 68 adrenergic receptors 68 antiproliferative activity 68 synthetase 68 chimeric monoclonal antibody 68 CDKs 68 antisense inhibitor 68 LRAT 68 colon carcinoma 68 Eg5 68 Cyclooxygenase 68 phosphatidylinositol 68 cell signaling pathway 68 protein interleukin 68 potently inhibits 68 focal adhesion kinase 68 NS5A 68 prostaglandin D2 68 receptor blocker 68 PKC isoforms 68 OCT4 68 mitogen 68 histone acetyltransferase 68 Immunohistochemical analysis 68 PPARγ 68 VEGFR2 68 Mutational 68 TGF beta 68 TGF ß1 68 protein tyrosine phosphatases 68 Kinase Inhibitor 68 syngeneic 68 alpha#beta# integrin 68 Hedgehog signaling pathway 68 NKX#.# 68 PAR1 68 TGFβ 68 nitric oxide synthase 68 H#K# [002] 68 RANKL 68 Caspase 68 Granulocyte Colony Stimulating Factor 68 GNAQ 68 TGF beta1 68 pDCs 68 MT1 MMP 68 anti CD3 68 5 HT1A 68 Dystrophin 68 antibody MAb 68 thymidylate synthase 68 potent topoisomerase II 68 sphingomyelin 68 Bruton tyrosine kinase 68 histone deacetylase HDAC 68 peptide receptor 68 Inactivation 68 Derived Factor 68 IGF 1R 68 potent inhibition 68 PI3K/mTOR 68 CD1d 68 fibroblast growth 68 pharmacological inhibition 68 Kv#.# 68 CYP# [002] 68 phosphatases 68 PKM2 68 Raf kinase 68 glycosyltransferase 68 matrix metalloproteinases 68 Cdc7 68 GPx 68 ErbB3 68 5' monophosphate 68 enzyme inhibitor 68 TGF β 68 T#M 68 mda 7 68 CagA 68 IFNg 68 mononuclear 68 neurite outgrowth 68 TNFα 68 thioredoxin 68 protein CETP 68 upregulate 68 RAF kinase 68 RANTES 68 immune modulatory 68 hepatoma 68 glucokinase 68 methyltransferase 68 DNA intercalator 68 mutational status 68 Lymphocytic 68 depsipeptide 68 microglial 67 pro apoptotic 67 NF κB 67 anti apoptotic 67 Gleevec resistant 67 β cells 67 HDAC enzymes 67 small molecule thrombopoietin 67 small molecule Hedgehog 67 CD4 + CD# 67 paxillin 67 protein tyrosine phosphatase 67 induce apoptosis 67 coronary vasodilation 67 kinesin spindle protein 67 coactivator 67 Src kinases 67 mineralocorticoid 67 Tumour Necrosis Factor 67 STAT3 67 P#Y# [001] 67 vinca alkaloid 67 accumulate preferentially 67 transgenic mouse model 67 copper zinc superoxide 67 E3 ligase 67 Vascular Endothelial Growth 67 histone H3 67 intracellular signaling 67 5HT 67 GATA3 67 neurotrophin 67 SGPT 67 macrophage colony stimulating 67 oral prodrug 67 phospho 67 cholecystokinin CCK 67 von Willebrand Factor vWF 67 Transcription Factor 67 liposomal formulation 67 NMDA N 67 Anti Tumor 67 cytokine interleukin 67 granulocyte macrophage colony stimulating 67 K + ATPase 67 Aromatase 67 Superoxide 67 aspartate 67 PGE2 67 peripheral blood mononuclear 67 triggers apoptosis 67 fast skeletal troponin 67 Tubulin 67 enhance ApoA 67 CD# CD# 67 IFN gamma 67 PHD2 67 somatostatin analogue 67 extracellular domain 67 reversible inhibitors 67 arginase 67 promoter methylation 67 DNA methyltransferases 67 mitogenic 67 small molecule defensin 67 dependent protein kinase 67 Beta catenin pathway 67 IGFBP 3 67 cytochrome P# #A# 67 alpha TNF 67 MAPK pathway 67 defensin 67 A3 adenosine receptor 67 uPA 67 PI3K inhibitor 67 Bone Morphogenetic Protein 67 heparanase 67 underlying vasculopathy 67 Leydig cells 67 chronic eosinophilic leukemia 67 FUS1 67 beta actin 67 nutlin 3a 67 SGLT 67 Fibroblast Growth Factor 67 PTPN# 67 histone acetylation 67 Survivin 67 CCR2 67 gluconeogenesis 67 Rho kinase 67 mRNA translation 67 exocrine 67 Mucosal 67 ectopic expression 67 mesenchymal cell 67 ERBB2 67 serotonin receptor 67 Wnt signaling 67 Neutrophil 67 metabolic enzymes 67 FOXP3 67 phosphate dehydrogenase 67 cytochrome P 67 Th1 cells 67 erythropoietic 67 targeting CD# 67 Catenin 67 generation antisense inhibitor 67 erlotinib Tarceva ® 67 LDLR 67 MDM2 67 antioxidant enzyme 67 PKC alpha 67 aromatase 67 oxidative phosphorylation 67 immunomodulator 67 glycosylated 67 Elvitegravir 67 uncoupling protein 67 mTOR signaling 67 LTB4 67 potent inducer 67 Phospholipase A2 67 Extracellular 67 p#Kip# 67 5 HT2A receptor 67 steroidogenesis 67 phosphatase 67 immuno modulatory 67 hormone LHRH 67 metabotropic glutamate receptor 67 prostate epithelial cells 67 galectin 67 GPR# [002] 67 lymphotoxin 67 Dysregulation 67 Akt 67 TTR gene 67 TIMP 67 suppressor cells 67 hTERT 67 mRNA encoding 67 miR #a [001] 67 Integrin 67 MetAP2 67 cMET 67 vascular disrupting agents 67 EphB4 67 Antitumor 67 TRAIL receptors 67 receptor PPAR 67 SETDB1 67 tumorigenicity 67 irreversible inhibitor 67 NF kappaB 67 dihydrofolate reductase 67 ADAMTS# 67 mTOR 67 melanocyte 67 alkylating 67 encodes protein 67 GSTT1 67 Hsp# Inhibitor 67 T#I mutant 67 HCV replication 67 neurotrophic factor 67 GRP# 67 enkephalin 67 dehydrogenase 67 dephosphorylation 67 retinoid X 67 leukocyte adhesion 67 triacylglycerol 67 5 HT6 receptor 67 tensin homolog 67 mTOR pathway 67 hedgehog pathway 67 glutamyl 67 PECAM 67 Wnt beta catenin 67 Bcl xL 67 Th1 67 CK2 67 glucocerebroside primarily 67 HER2 HER2 67 CXCR2 67 TNF receptor 67 PKC enzyme 67 CD# monoclonal antibody 67 complement inhibitor eculizumab 67 diphosphate 67 costimulation 67 cofilin 67 CCR1 67 palmitate 67 deoxy 67 effector functions 67 potent anti angiogenic 67 Fc fusion protein 67 cytokines interleukin 67 protein p# 67 ligand receptor 67 renal fibrosis 67 bcl 2 67 B lymphocyte 67 dasatinib Sprycel ® 67 ACh 67 Peroxisome proliferator activated 67 endothelin receptor 67 G Protein Coupled 67 replicon 67 tRNA synthetase 67 tumor xenograft models 67 cytokine receptors 67 integrin receptor 67 small molecule tyrosine 67 plasma kallikrein 67 cardiac fibroblasts 67 Angiotensin Converting Enzyme 67 FGFs 67 cardiolipin 67 haematopoietic 67 imatinib resistant 67 IFN alpha 67 immunomodulatory effects 67 mGluR4 67 TNF IL 67 AKT inhibitor 67 hepatic lipase 67 receptor tyrosine kinase inhibitor 67 hematopoiesis 67 sPLA2 67 bronchoalveolar lavage fluid 67 proliferator activated receptor 67 epithelial tumors 67 FGFR4 67 Mesenchymal 67 Runx2 67 muscarinic receptors 67 γ secretase 67 glucocorticoid receptors 67 BMAL1 67 CCL# 67 matrix metalloproteases 67 CCL2 67 fibrin deposition 67 transthyretin 67 Vidofludimus 67 sphingolipid 67 VEGFR 67 5 HT6 67 osteoclast formation 67 cisplatin resistant 67 Factor NGF 67 mitochondrial biogenesis 67 Endothelial 67 melatonin receptor 67 sulfatase 67 dismutase 66 Antitumor Activity 66 Modulates 66 Epothilones 66 heterodimers 66 ribonuclease 66 alpha GAL 66 anionic backbone 66 targeted radiotherapeutic 66 EZN 66 β2 66 SH2 domain 66 ß1 66 sortilin 66 carboxyl terminal 66 TrkA 66 plasmid encoding 66 cyclic peptide 66 nicotinic receptor 66 inhibits protein synthesis 66 CFTR cystic fibrosis transmembrane 66 Pegylated 66 fatty acid oxidation 66 KLF4 66 superoxide dismutase SOD 66 #HT#A 66 PPAR alpha 66 allergic inflammation 66 Myeloid 66 gene encodes 66 sunitinib Sutent ® 66 somatostatin receptors 66 Alu RNA 66 p#NTR 66 RRM1 66 MAPKs 66 protein secreted 66 H#K# methylation 66 immune modulating 66 galectins 66 constitutively 66 KLF2 66 alpha2 66 inflammasome 66 AAG geldanamycin analog 66 TET2 66 IGFBP2 66 ADAM# 66 oncogenic transformation 66 GLUT4 66 Foxp3 66 Hepcidin 66 converting enzyme 66 LPA1 receptor 66 Bcl 66 overexpress 66 sphingosine kinase 66 receptor antagonists 66 Stat3 66 chitinase 66 PDE1 66 JUVISTA R Human 66 endogenous ligands 66 TGR5 66 Pim kinases 66 nucleoside analog 66 BRAF kinase 66 ,#,# [002] 66 eIF 4E 66 myocyte enhancer factor 66 hypothalamic pituitary 66 PIK3CA 66 apolipoprotein AI 66 enzymatic activity 66 tyrosine hydroxylase 66 acinar 66 imatinib Gleevec 66 tumorigenesis 66 peptide hormone 66 experimental autoimmune encephalomyelitis 66 SREBP 66 Pralatrexate 66 vimentin 66 hepatocyte 66 polysaccharide polymer 66 polyglutamate 66 cell adhesion molecules 66 Six3 66 ADP receptor antagonist 66 Endothelial Cells 66 glycolipids 66 intratumoral injection 66 cholesteryl ester transfer 66 intracellular protein 66 acetylcholinesterase AChE 66 novel topoisomerase 66 PDE#A 66 TXNIP 66 R Saizen R 66 monocyte chemoattractant protein 66 CRAC channel 66 osteocalcin 66 Panzem R 66 Sphingosine 1 66 selective kinase inhibitor 66 cellular metabolism 66 cis retinoic acid 66 Rac1 66 cytoplasmic domain 66 PPAR peroxisome proliferator activated 66 Multiple Myeloma MM 66 Heterozygous 66 focal adhesion kinase FAK 66 alpha antagonist 66 #ß 66 regulator CFTR gene 66 Kinoid 66 P selectin 66 rhIL 7 66 syntaxin 66 ENMD #