Related by context. All words. (Click for frequent words.) 70 APTIVUS r 69 urate lowering therapy 69 GERD symptoms 69 hypomagnesemia 68 recurrent VTE 68 atherothrombotic events 68 intravitreal injections 68 tapentadol ER 68 NATRECOR R 67 CIMZIA ™ 67 OAB symptoms 67 PASI scores 67 delayed CINV 67 oxycodone CR 67 severe exacerbations 67 endophthalmitis 67 spontaneous bowel movements 67 hematologic toxicity 67 RLS symptoms 67 thromboembolic events 67 serum urate 67 severe neutropenia 67 adalimumab 67 hypoglycemic events 67 RLAI 66 acute gout flares 66 EXJADE 66 upper gastrointestinal bleeding 66 COPD exacerbations 66 VIIBRYD 66 incontinence episodes 66 ACTEMRA TM 66 teriflunomide 66 BPH symptoms 66 morphometric vertebral fractures 66 FOLFOX4 66 delayed onset CINV 66 cerebrovascular events 66 annualized relapse 66 TEAEs 66 MULTAQ 66 dose colchicine 66 tolvaptan 66 hypercalcemia 65 sustained virologic response 65 PREZISTA r 65 venous thromboembolic events 65 virologic failure 65 PRADAXA 65 postoperative inflammation 65 tamsulosin 65 Hypotension 65 docetaxel chemotherapy 65 lopinavir r arm 65 nephrotoxicity 65 FROVA 65 PROMACTA 65 prednisone prednisolone 65 LANTUS R 65 mcg QD 65 CIMZIA TM 65 8mg/kg 65 bosentan 65 glycated hemoglobin levels 65 virologic response 65 nab paclitaxel 65 dosing cohorts 65 dose titration 65 HbA1c levels 65 PRADAXA #mg 65 serum phosphate levels 65 #mg BID [001] 65 #mg/day [002] 65 ARCOXIA 65 dosage regimens 65 solifenacin 65 plus methotrexate 65 intermittent claudication 65 octreotide LAR 65 desvenlafaxine succinate 65 oral rivaroxaban 64 ARCALYST ® 64 symptomatic hypotension 64 cytogenetic response 64 Infusion Reactions Severe 64 LEXIVA r 64 subcutaneous enoxaparin 64 postoperative AF 64 alpha blocker 64 salmeterol fluticasone 64 severe oral mucositis 64 opioid analgesia 64 nonvertebral fractures 64 recurrent genital herpes 64 febrile neutropenia 64 postoperative mortality 64 peripheral sensory neuropathy 64 ALT flares 64 ARIXTRA 64 #mg dose [003] 64 intravenous bisphosphonates 64 gout flare 64 invasive aspergillosis 64 receiving golimumab 64 mg QD 64 conjunctival hyperemia 64 KAPIDEX 64 post herpetic neuralgia 64 QTc interval 64 PRISTIQ 64 reinfarction 64 achieved ACR# 64 β blockers 64 4mg/kg 64 events AEs 64 adalimumab Humira 64 HBeAg seroconversion 64 HbA 1c levels 64 elevated intraocular pressure 64 oral FTY# 64 thrombotic events 64 endometrial hyperplasia 64 evaluable subjects 64 cilostazol 64 ibandronate 64 ruboxistaurin 64 Elitek 64 FOLFIRI 64 hypoglycemic episodes 64 biologic DMARD 64 candesartan 64 peginterferon alfa 2a 64 posaconazole 64 uric acid lowering 64 QTc prolongation 64 serum phosphate 64 PEGINTRON TM 64 hematological toxicity 63 plasma uric acid 63 moderate renal impairment 63 insulin detemir 63 paroxysmal AF 63 FOLPI regimen 63 systemic corticosteroid 63 TORISEL 63 BENICAR HCT 63 arterial thromboembolic events 63 nocturnal hypoglycaemia 63 biochemical relapse 63 oral allopurinol 63 postherpetic neuralgia 63 draining enterocutaneous 63 ACTEMRA 63 discontinuations due 63 edoxaban 63 deferiprone 63 HCV RESPOND 2 63 corticosteroid therapy 63 HBV DNA levels 63 atazanavir ritonavir 63 virological failure 63 ipsilateral stroke 63 CINV 63 dose cohort 63 DAPT 63 adjunctive placebo 63 timepoint 63 tolterodine ER 63 macrovascular 63 COPD exacerbation 63 dosage regimen 63 Lamictal XR 63 ritonavir boosted 63 efalizumab 63 telaprevir dosing 63 rosuvastatin #mg 63 aminotransferase elevations greater 63 rFVIIa 63 Tekamlo 63 paroxetine Paxil 63 generalized seizures 63 ximelagatran 63 QD dosing 63 post herpetic neuralgia PHN 63 corticosteroid dose 63 EDARBI 63 AGILECT R 63 inflammatory lesions 63 sUA 63 pruritus itching 63 treprostinil 63 Serious adverse reactions 63 postoperative atrial fibrillation 63 Natalizumab 63 generalized edema 63 anthracycline taxane 63 HBeAg positive patients 63 bisphosphonate therapy 63 metformin accumulation 63 FOLPI 63 NATRECOR ® 63 relapsing MS 63 ULORIC 63 cardiac toxicity 63 Lupuzor ™ 63 mcg kg 63 nicardipine 63 FASLODEX 63 postsurgical pain 63 invasive candidiasis 63 antiarrhythmic drug 63 baminercept 63 claudication 63 low dose Iluvien 63 INCB# [003] 63 sustained virological response 63 hyperphenylalaninemia HPA due 63 gastrointestinal perforation 63 #mg/day [001] 63 PONV 63 anakinra 63 divalproex sodium 62 zolmitriptan 62 nocturnal awakenings 62 severe hypoglycemic 62 INVEGA ® 62 peginterferon 62 hypophosphatemia 62 proliferative diabetic retinopathy 62 clopidogrel Plavix 62 relapsed MM 62 ropinirole 62 binary restenosis 62 oral diclofenac 62 MS relapses 62 GnRH agonists 62 recurrent atrial fibrillation 62 REYATAZ r arm 62 hemoglobin A1c HbA1c 62 severe renal impairment 62 flutamide 62 postprocedure 62 potent CYP#A# inhibitors 62 diabetic neuropathic pain 62 pulmonary exacerbation 62 Pegasys plus Copegus 62 DETROL LA 62 tumor lysis syndrome 62 GnRH agonist 62 PRE SURGE 62 elevated IOP 62 serum phosphorus 62 stable angina 62 adjunctive ABILIFY 62 virological response 62 dosing cohort 62 ribavirin therapy 62 mg kg dose 62 placebo dexamethasone 62 certolizumab pegol 62 definite stent thrombosis 62 chlorambucil 62 certolizumab 62 nonvertebral fracture 62 oral prednisone 62 primary generalized tonic 62 triamcinolone 62 glucocorticoid therapy 62 CIPN 62 mycophenolate mofetil 62 refractory gout 62 NPH insulin 62 clomipramine 62 clodronate 62 secondary efficacy endpoint 62 MADRS score 62 acne lesions 62 HPA axis suppression 62 pyridostigmine 62 angiographic outcomes 62 oral antidiabetic medication 62 vasospasm 62 CDI recurrence 62 CrCl 62 A1c levels 62 fasting plasma glucose 62 Febrile neutropenia 62 Toxicities 62 onset seizures 62 atherogenic dyslipidemia 62 Thrombocytopenia 62 mg BID 62 Eltrombopag 62 painful diabetic neuropathy 62 oral corticosteroids 62 vertebral fracture 62 quetiapine XR 62 placebo p = 62 receiving INTRON 62 recurrent venous thromboembolism 62 hemoglobin A1c levels 62 orthostatic hypotension 62 TNF antagonist 62 nasal symptoms 62 symptomatic VTE 62 colectomy 62 systemic embolism 62 severe hypersensitivity reactions 62 hemorrhagic complications 62 interferon ribavirin 62 thromboembolic 62 EDSS scores 62 gouty arthritis 62 EFFEXOR XR 62 keloid scarring 62 stent implantation 62 ALA PDT 62 ocular adverse 62 antihypertensive medications 62 AVELOX 62 detectable HCV RNA 62 variceal bleeding 62 serum cortisol 62 generalized anxiety disorder GAD 62 dose cohorts 62 dyspareunia 62 antiplatelet medication 62 μg dose 62 #mg doses [002] 62 CMV disease 62 intravitreal injection 62 serum calcium levels 62 Events MACE 62 APTIVUS 62 PEGylated interferon beta 1a 62 androgen suppression 62 receiving VELCADE 62 forodesine 62 Durezol 62 symptomatic BPH 62 Adalimumab 62 asymptomatic carotid stenosis 61 cholinesterase inhibitor 61 serum potassium levels 61 levodopa therapy 61 abatacept 61 ropivacaine 61 microvascular complications 61 post operative ileus 61 VELCADE melphalan 61 coadministration 61 urinary symptoms 61 plasma HCV RNA 61 Traficet EN 61 aripiprazole 61 bronchospasm 61 gastrointestinal toxicities 61 LEXIVA 61 bolus dose 61 monoamine oxidase inhibitors MAOIs 61 #mg/m# [001] 61 enalapril 61 undetectable HCV RNA 61 primidone 61 Torisel 61 relapsing remitting multiple sclerosis 61 vasomotor symptoms 61 plus ribavirin 61 mcg BID 61 highly emetogenic 61 esomeprazole Nexium 61 canakinumab 61 AGILECT ® 61 sUA levels 61 EVIZON 61 mucositis 61 antihypertensive therapy 61 FOLFIRI alone 61 menstrual migraine 61 aminotransferases 61 PAOD 61 Fibrillex TM 61 serum urate levels 61 plus dexamethasone 61 candidemia 61 renal toxicity 61 postoperative bleeding 61 warfarin therapy 61 mucosal healing 61 clinically meaningful improvements 61 severe hypoglycemia 61 CANCIDAS 61 HbA 1c 61 systemic corticosteroids 61 retinal thickness 61 extrapyramidal symptoms 61 diabetic gastroparesis 61 leucopenia 61 induce orthostatic hypotension 61 RSD# oral 61 hepatic impairment 61 ACAPODENE 61 blastic phase 61 salivary flow 61 ATACAND 61 subtrochanteric 61 tocilizumab 61 XGEVA 61 alteplase 61 IBS symptoms 61 ARB telmisartan 61 #.#mg/dL 61 colorectal adenoma 61 cytogenetic responses 61 XIENCE V PROMUS Stent 61 diarrhea nausea fatigue 61 deep venous thromboses 61 angiographic restenosis 61 acarbose 61 myelosuppression 61 intravenous methylnaltrexone 61 BROVANA 61 blood phenylalanine Phe 61 intracerebral hemorrhage 61 teriparatide 61 Aloxi injection 61 postoperative ileus POI 61 DMARD therapy 61 Cimzia ® 61 STRIDE PD 61 Peg IFN 61 asthma exacerbation 61 hypokalemia 61 5-FU/LV 61 alfa 2a 61 TREDAPTIVE 61 Free Survival PFS 61 Erythropoietic therapies may 61 ARIMIDEX 61 eptifibatide 61 Kepivance 61 homozygous familial hypercholesterolemia 61 antimuscarinic 61 acromegalic patients 61 non hematological toxicities 61 QTc 61 azacitidine 61 hypoglycaemic episodes 61 pioglitazone HCl 61 mitoxantrone 61 Psoriasis Area 61 neurologic progression 61 intravascular hemolysis 61 postoperative nausea 61 placebo controlled clinical 61 DEXILANT 61 zonisamide SR 61 ribavirin RBV 61 alfuzosin 61 achieved PASI 61 Restenosis 61 REMICADE ® 61 riociguat 61 primary hypercholesterolemia 61 titration phase 61 icatibant 61 dexamethasone Decadron 61 prodromal symptoms 61 oral antidiabetes 61 MACCE 61 abdominal pain abdominal discomfort 61 TOPAMAX 61 tiotropium 61 gastrointestinal toxicity 61 #mg dose [002] 61 laboratory abnormalities 61 β blocker 61 postoperative pain 61 piperacillin tazobactam 61 alvimopan 61 active comparator 61 reflux symptoms 61 mg/m2 dose 61 left ventricular dysfunction 61 urinary retention 61 plasma glucose levels 61 BENICAR 61 recurrent glioblastoma multiforme 61 cerebral vasospasm 61 retinal vein occlusion RVO 61 myopathy rhabdomyolysis 61 oral corticosteroid 61 radiographic progression 61 ALND 61 treat dysmenorrhea 61 serum clusterin levels 61 #.#/#.# mmHg [001] 60 postoperative morbidity 60 idraparinux 60 glatiramer acetate 60 fistula closure 60 MYCAMINE 60 carboplatin paclitaxel 60 fluticasone salmeterol 60 ZYVOX 60 lopinavir r 60 transurethral resection 60 vandetanib 60 hyperkalemia 60 Dasatinib 60 #mmHg [001] 60 KOMBIGLYZE XR 60 undetectable viral 60 ribavirin USP 60 FOLFOX6 60 macroalbuminuria 60 opioid induced bowel dysfunction 60 Gabapentin GR 60 leukopenia 60 pouchitis 60 gastrointestinal adverse reactions 60 urinary N telopeptide 60 ketoconazole 60 symptomatic hyponatremia 60 knee osteoarthritis OA 60 lumbar spine BMD 60 superficial bladder cancer 60 PREZISTA r arm 60 thrombotic complications 60 ALGRX 60 paroxysmal atrial fibrillation 60 oxcarbazepine 60 dosing intervals 60 visilizumab 60 ZOLINZA 60 lacosamide 60 IV bolus 60 phase IIb trial 60 DMARD 60 nadolol 60 REYATAZ ritonavir 60 KRAS mutations occur 60 Tiotropium 60 mg dose 60 receiving XGEVA 60 candesartan cilexetil 60 intra articular injection 60 valacyclovir 60 chemoradiotherapy 60 renal dysfunction 60 proton pump inhibitor PPI 60 noninfectious uveitis 60 androgen deprivation 60 mg TID 60 comparator arm 60 R# #mg BID 60 revascularization procedures 60 telaprevir dosed 60 serum uric acid 60 renal flares 60 dapagliflozin plus 60 BYSTOLIC 60 LAMICTAL 60 sertraline Zoloft 60 ARCALYST 60 IOP lowering 60 tirofiban 60 Adverse events 60 lomitapide 60 menstrual bleeding 60 complete cytogenetic response 60 standard chemotherapy regimen 60 BARACLUDE ® 60 rapid virologic response 60 atheroma volume 60 urate lowering 60 exacerbations 60 apremilast 60 albiglutide 60 intraocular inflammation 60 IELT 60 allopurinol 60 erythema redness 60 anticoagulation therapy 60 nighttime awakenings 60 FIRMAGON 60 beta blocker therapy 60 vertebral fractures 60 thromboembolism 60 revascularizations 60 serum testosterone 60 AVANDIA 60 gemifloxacin 60 cytopenias 60 calculated creatinine clearance 60 palifermin 60 creatinine clearance 60 serum phosphorous 60 BoNTA 60 haloperidol Haldol 60 A1C levels 60 unresectable HCC 60 prolonged QT interval 60 postoperative complication 60 MoxDuo TM IR 60 rt PA 60 MoxDuo IR 60 paricalcitol 60 Angioedema 60 antiandrogen 60 nonmetastatic prostate cancer 60 gastric stomach ulcers 60 AZOR 60 alanine aminotransferase 60 mL/min/#.# m 2 60 #.#g/day 60 plus MTX 60 clinically meaningful improvement 60 elotuzumab 60 mcg kg REBETOL 60 severe hypoglycaemia 60 RAPTIVA 60 ischemic complications 60 strong CYP#A# inducers 60 rebleeding 60 tipranavir 60 APTIVUS ritonavir 60 oral vancomycin 60 Hepatotoxicity 60 #mg BID [003] 60 perioperative mortality 60 elagolix 60 fraction LVEF 60 pregabalin 60 hyperalgesia 60 T2DM 60 paresthesias 60 myocardial ischemia 60 INTEGRILIN R 60 statin monotherapy 60 bezafibrate 60 pericardial effusion 60 liver resection 60 dopaminergic therapy 60 GOUT 60 COPAXONE R 60 painful menstruation 60 trastuzumab Herceptin ® 60 Raptiva r 60 non menstrual pelvic 60 Pioglitazone 60 CR CRu 60 venlafaxine Effexor 60 anterior uveitis 60 spine fractures 60 femoral shaft fractures 60 gastric pH 60 dysmenorrhoea 60 MCyR 60 ACR# response 60 Monotherapy 60 salmeterol inhalation powder 60 pentoxifylline 60 docetaxel Taxotere ® 60 bowel resection 60 tolterodine 60 aspartate aminotransferase AST 60 dosing interval 60 mg ustekinumab 60 zoledronic acid 60 baseline HbA1c 60 MIRAPEX 60 Thal Dex 60 beclomethasone dipropionate 60 chemoradiation therapy 60 partial onset seizures 60 timepoints 60 composite endpoint 60 valdecoxib 60 CYPHER Stent 60 Keppra R 60 rotigotine 60 KETEK 60 Major Depressive Disorder MDD 60 CIMZIA 60 arthralgias 60 levetiracetam 60 periprocedural 60 dose regimens 60 recurrent ischemia 60 Soliris therapy 60 PSA nadir 60 xanthine oxidase inhibitor 60 platelet inhibition 60 adenotonsillectomy 60 treatment emergent adverse 60 transaminases 60 Postoperative complications 60 odanacatib 60 thromboembolic complications 60 risedronate Actonel 60 gastrointestinal bleeds 60 hypocalcemia 60 acute GvHD 60 eosinophilic asthma 60 NovoLog ® Mix 60 peg IFN 60 NOLVADEX 60 NEXIUM 60 repeat paracentesis 60 hepatotoxicity 60 blepharospasm 60 neutropenia dehydration dyspnea 60 Dose escalation 60 placebo controlled studies 60 trials RCTs 60 Perforomist Inhalation Solution 60 pathologic fracture 60 Pegasys ® 60 CSBMs 59 DLTs 59 xerostomia 59 PSADT 59 bicifadine 59 hypertrophic scars 59 fallopian tube cancers 59 AVODART 59 atrophic gastritis 59 TMC# r 59 #mg QD [001] 59 heterozygous FH 59 tumor recurrence 59 OADs 59 Bosentan 59 systolic hypertension 59 angiotensin converting enzyme inhibitor 59 Ranolazine 59 leukemia AML 59 VAPRISOL 59 maximal doses 59 antithrombotic therapy 59 tumor shrinkage 59 curative resection 59 antiretroviral naive 59 radioiodine therapy 59 refractory NSCLC 59 clopidogrel therapy 59 DMARDs 59 bronchodilation 59 doxazosin 59 rimonabant #mg/day 59 external genital lesions 59 vaginal atrophy 59 heavy menstrual bleeding 59 abacavir lamivudine 59 serum aminotransferase levels 59 serum potassium 59 abciximab 59 DOXIL 59 remission CR 59 bone metastasis 59 hemoptysis 59 clonic seizures 59 autoantibody positive 59 ADHF 59 hypersensitivity reaction 59 menopausal symptom 59 TNF Tumor Necrosis Factor 59 dacarbazine 59 bronchial thermoplasty 59 lixisenatide 59 detrusor overactivity 59 lamotrigine 59 omeprazole Prilosec 59 infusional 59 IFN alfa 59 GLP1 agonist 59 infusion reactions 59 H2 receptor antagonists 59 vitreous hemorrhage 59 NNT = 59 placebo controlled Phase 59 ERBITUX therapy 59 Insulin PH# 59 post thrombotic syndrome 59 TDF FTC 59 TNF inhibitor 59 Ejection Fraction 59 virologic breakthrough 59 Aortic Stenosis 59 postherpetic neuralgia PHN 59 endometrial carcinoma 59 acute decompensation 59 Hypersensitivity reactions 59 LVEF 59 inhibitor RG# 59 NOXAFIL 59 hematologic adverse 59 advanced adenoma 59 budesonide formoterol 59 neutropenic patients 59 XIENCE V demonstrated 59 sotalol 59 VFEND 59 Viread Emtriva 59 mg q8h 59 goserelin 59 EDSS score 59 CIMZIA TM certolizumab pegol 59 Pemetrexed 59 FFNS 59 pulmonary exacerbations 59 6R BH4 59 mg administered orally 59 ARICEPT 59 carotid endarterectomy CEA 59 lipid lowering therapy 59 etanercept 59 postoperative chemotherapy 59 nitazoxanide 59 lispro 59 olmesartan 59 dysuria 59 neutrophil counts 59 AZILECT 59 idarubicin 59 ULTRAM ER 59 purpura ITP 59 Telintra 59 prospectively stratified 59 symptomatic intracranial 59 clinically meaningful reductions 59 otamixaban 59 steroid dexamethasone 59 QT prolongation 59 tacrolimus ointment 59 neutrophil count 59 tamoxifen therapy 59 PGTC seizures 59 sitaxsentan 59 ACZ# 59 mitoxantrone plus 59 progression TTP 59 receiving prophylactic anticoagulation 59 nortriptyline 59 ZOMIG Nasal Spray 59 HAM D# scores 59 INVEGA R 59 Oral corticosteroids 59 Doxil ® 59 TMP SMX 59 mg/m2/day 59 Treatment emergent adverse 59 contrast induced nephropathy 59 LYSTEDA 59 Secondary endpoints 59 tumor necrosis 59 mg RDEA# 59 ecchymosis 59 pretreatment baseline 59 lymphocytosis 59 pimecrolimus 59 DPNP 59 REYATAZ 59 timolol 59 recurrent stroke 59 symptomatic intracranial hemorrhage 59 peginterferon alfa 59 Ophena TM 59 evaluating tivozanib 59 LATUDA 59 decitabine 59 aldosterone antagonist 59 active ankylosing spondylitis 59 eplerenone 59 macular edema 59 #mg/m# [002] 59 HbA1C levels 59 postmenopausal osteoporotic women 59 bisphosphonate 59 retinal vein occlusion 59 ulcer healing 59 mesalamine granules 59 argatroban 59 Sustained Virological Response 59 Hydroxyurea 59 non metastatic osteosarcoma 59 myalgia arthralgia 59 cinacalcet 59 estramustine 59 RAPAFLO R 59 RoACTEMRA 59 serum triglyceride levels 59 postintervention 59 amoxicillin clavulanate 59 acute mania 59 intravenous cyclophosphamide 59 aspartate aminotransferase 59 Scale EDSS 59 rectovaginal fistulas 59 budesonide pMDI 59 molindone 59 COMBIVIR 59 cobiprostone 59 cabazitaxel 59 intermittent dosing 59 postop 59 RRMS patients 59 bone marrow reticulin 59 perioperative complications 59 NSAID therapy 59 eltrombopag 59 proteinuria 59 eculizumab therapy 59 non squamous NSCLC 59 idiopathic thrombocytopenic purpura ITP 59 PEG INTRON 59 corrected QT interval 59 docetaxel prednisone 59 artery stenosis 59 INFERGEN 59 elective PCI 59 acute gout 59 QTcF 59 administered subcutaneously 59 acutely decompensated congestive heart 59 febuxostat 59 rimonabant #mg 59 Lantus ® 59 adrenal insufficiency 59 CCyR 59 adrenal suppression 59 amphotericin B 59 vaginal hysterectomy 59 oxymorphone ER 59 weekly subcutaneous injections 59 hallucinations dyskinesia 59 HoFH 59 weekly intravenous infusions 59 nadroparin 59 FOSRENOL ® 59 EGFRIs 59 mg qd 59 voriconazole 59 MAOI 59 bone metastases 59 tipranavir r 59 infarct size 59 bleeding pallor 59 dosing frequency 59 Zoledronic acid 59 ELOXATIN 59 ischemic cardiomyopathy 59 REYATAZ r 59 subcutaneous injections 59 Hb A1C 59 fluvastatin 59 infliximab 59 Welchol 59 ziprasidone 59 underwent resection 59 serum HCV RNA 59 paracentesis 59 heparin induced thrombocytopenia 59 carotid stenosis 59 relapsed refractory multiple myeloma 59 biochemical recurrence 59 postoperatively 59 peripheral arterial occlusive disease 59 ONGLYZA 59 INC# 59 pegylated interferon alpha 59 atrioventricular block 59 laxation 59 peg interferon 59 herpes zoster 59 metformin sulfonylurea 59 hypogonadal men 59 cardiovascular hospitalization 59 CR nPR 58 saline placebo 58 esomeprazole 58 hour bronchodilation 58 neutropaenia 58 related hematological toxicity 58 catheter occlusion 58 p = NS 58 CLARITY study 58 Cimzia R 58 AA Amyloidosis 58 HeFH 58 VIRAMUNE XR 58 Aptivus ® 58 events TEAEs 58 FOLFOX 58 CorVue ™ 58 debilitating complication 58 acute GVHD 58 intravenous diuretics