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(Click for frequent words.) 76 gene polymorphisms 72 genetic loci 72 genetic variants associated 72 ABCB1 71 biologic pathways 71 PTPN# 71 genetic determinants 71 bile acid metabolism 71 underlying pathophysiology 70 polymorphisms 70 gene locus 70 Genetic variants 70 VKORC1 70 SLC#A# [002] 70 susceptibility loci 70 genes CYP#C# 70 APOE genotype 70 susceptibility gene 70 prognostic significance 70 etiologic 69 gene polymorphism 69 gene variants 69 genetic variants 69 clinicopathological 69 genetic polymorphism 69 MTHFR 69 K ras mutations 68 rs# [004] 68 prostate cancer CaP 68 prognostic indicators 68 prognostic marker 68 LRRK2 gene 68 prognostic markers 68 Genetic variations 68 germline mutations 68 TCF#L# gene 68 pathogenic mechanisms 68 susceptibility locus 68 MSH2 68 causative genes 68 familial clustering 68 endophenotypes 68 molecular subtypes 67 functional polymorphism 67 receptor subtypes 67 SNP rs# [001] 67 chromosome #p#.# 67 MYH9 67 susceptibility genes 67 somatic mutations 67 HLA DRB1 67 MGUS 67 WNK1 67 causal variants 67 methylation patterns 67 epigenetic mechanisms 67 LRP5 67 miRNA expression 67 genomic alterations 67 GSTP1 67 missense mutations 67 potentially modifiable 67 chromosomal regions 67 sporadic ALS 67 breast cancer metastasis 66 pathophysiological 66 DNA methylation patterns 66 Logistic regression 66 genetic locus 66 molecular biomarkers 66 PTEN mutations 66 IPAH 66 rs# [001] 66 GBA mutations 66 MYH9 gene 66 pathophysiological mechanisms 66 IgA deficiency 66 CYP#D# gene 66 differential gene expression 66 genomewide 66 PARP inhibition 66 protein isoforms 66 Subgroup analyzes 66 metabolic dysfunction 66 #q# deletion 66 PALB2 66 drug metabolizing enzymes 66 ZNF# 66 rs# [002] 66 KIAA# 66 Genetic variation 66 alexithymia 66 cardioprotective effects 66 modifier genes 66 causal pathways 66 subclinical atherosclerosis 66 narcolepsy cataplexy 66 monogenic 66 adipokines 66 genetic variations 66 beta1 integrin 66 virulence genes 66 S. maltophilia 66 PON1 66 dopamine receptor gene 66 CYP#C# genotype 66 5 HTTLPR 66 APOE e4 66 myopathies 66 CDH1 66 cardiac troponin T 66 etiologic factors 66 ADPKD 66 CYP#C# gene 66 hereditary predisposition 65 Multiple logistic regression 65 chromosomal aberrations 65 chromosomal rearrangement 65 epigenetic changes 65 Hp2 2 65 nondemented 65 TCF#L# 65 hamartomas 65 clusterin 65 FGFs 65 histone deacetylases 65 HER2 expression 65 nongenetic 65 KRAS oncogene 65 APOL1 65 microdeletions 65 MTHFD1L gene 65 IDH1 mutation 65 IL#R 65 genetic susceptibilities 65 Clusterin 65 FGFR2 65 CYP#C# [002] 65 SNCA 65 MTHFR gene 65 coinfection 65 EGFR mutations 65 C. pneumoniae 65 Leydig cell 65 #q# [001] 65 tumor subtypes 65 PPARγ 65 CSF biomarkers 65 Lp PLA 2 65 apoE 65 airway hyperresponsiveness 65 serum biomarkers 65 lipid abnormalities 65 cerebral microbleeds 65 BCL#A 65 Observational studies 65 IL#B 65 biochemical abnormalities 65 stratifying patients 65 CYP#C# [001] 65 SSc 65 underlying molecular mechanisms 65 INTERHEART study 65 allelic variants 65 uPAR 65 Hashimoto thyroiditis 65 angiographically 64 multivariate logistic regression 64 ERK signaling 64 microRNA expression 64 ependymomas 64 inherited mutations 64 metabolizing enzymes 64 dysglycemia 64 SMAD4 64 KRAS mutations 64 monozygotic twins 64 inflammatory biomarkers 64 multiple logistic regression 64 cardioembolic stroke 64 gene expression patterns 64 mitochondrial toxicity 64 arterial calcification 64 splice variants 64 tumor suppressor protein 64 phenotypic differences 64 CC genotype 64 apoE4 64 renal fibrosis 64 miRNA genes 64 biomarkers 64 LRRK2 mutation 64 vimentin 64 molecular abnormalities 64 chromosomal anomalies 64 thyrotropin 64 pilocytic astrocytomas 64 murine models 64 aneuploidies 64 JAK2 mutation 64 Sjögren syndrome 64 rs# [003] 64 prostate carcinogenesis 64 intracellular bacteria 64 myeloproliferative diseases 64 TGFBR1 * 6A 64 neuropathologic 64 cellular pathways 64 Genotypes 64 cardiac fibrosis 64 promoter hypermethylation 64 plasma kallikrein 64 GPx 64 Multivariate analysis 64 BARD1 64 serum leptin 64 chromosome #p# [002] 64 lipoprotein metabolism 64 ERBB2 64 genes differentially expressed 64 epigenetic alterations 64 motor neuron degeneration 64 GABA receptor 64 Estrogen Receptor 64 EGFR mutation status 64 predisposing factors 64 micro RNAs 64 de novo mutations 64 genetic biomarkers 64 prostate cancer PCa 64 CagA 64 metabolic abnormalities 64 CYP#D# genotype 64 aberrant methylation 64 apolipoprotein E gene 64 CYP#D# 64 MIF protein 64 plasma lipid 64 carotid plaques 64 chromosome #q# [001] 64 hypermethylated 64 synovial cells 64 #F FDG PET 64 synuclein 64 mtDNA mutations 64 pleiotropic effects 64 histological subtype 64 NRF2 gene 64 arrhythmogenic 64 circadian genes 64 cystatin C 64 predisposing factor 64 diagnostic biomarker 64 autoantigens 63 oxysterols 63 gallstone disease 63 hypermethylation 63 differentially expressed genes 63 hypothalamic pituitary adrenal axis 63 ABCB1 gene 63 Lp PLA2 63 colorectal adenoma 63 subclinical hypothyroidism 63 variant rs# 63 quantitative trait loci 63 alkaline phosphatase ALP 63 phenotypes 63 T2D 63 protein kinase C 63 thiopurine 63 autism susceptibility genes 63 apolipoproteins 63 multivariate analyzes 63 pathophysiologic 63 CHD7 63 familial aggregation 63 gene loci 63 serum BDNF 63 DNA methylation markers 63 SE alleles 63 UGT#A# gene 63 COX2 63 thrombophilia 63 neuroligins 63 Brugada syndrome 63 serous ovarian cancer 63 herpesviruses 63 mitochondrial DNA mtDNA 63 ADAMTS# 63 atherothrombotic disease 63 KLF4 63 β1 63 caveolin 63 FUS protein 63 chromosome aberrations 63 Apolipoprotein E 63 hepatocellular carcinomas 63 BRAF mutation 63 gastric carcinoma 63 SLC#A# [001] 63 SNP rs# [002] 63 prognostic biomarker 63 perilipin 63 HIV HCV coinfected 63 aetiology 63 cell signaling pathways 63 CNVs 63 BRAF V#E 63 metalloprotease 63 genetic aberrations 63 histone modifications 63 obesity insulin resistance 63 G6PD deficiency 63 immunohistochemical analysis 63 HLA DRB1 * 63 gene expression profiles 63 chitinase 63 T2DM 63 breast endometrial 63 CYP#A# [002] 63 epigenetic regulation 63 RRM1 63 Polymorphisms 63 subtypes 63 PIK3CA 63 sCJD 63 endogenous ligands 63 Multiple linear regression 63 SPINK1 63 autoimmune thyroid 63 atherothrombotic 63 miR #a [001] 63 mesotheliomas 63 obstructive coronary artery 63 missense mutation 63 gene rearrangements 63 aetiological 63 Subgroup analysis 63 Chlamydia pneumoniae 63 LRRK2 mutations 63 myeloproliferative 63 pathogenetic 63 transcriptomic 63 familial pancreatic cancer 63 allele frequencies 63 chromosomal alterations 63 hyperhomocysteinemia 63 FGFR2 gene 63 #p# [001] 63 chromosomal anomaly 63 #q#.# [001] 63 genotypic 63 prognostic variables 63 flavopiridol 63 estrogen metabolism 63 metabolite concentrations 63 proto oncogene 63 RBP4 63 immunohistochemical 63 carotid atherosclerosis 63 HbF 63 mRNA expression 63 biologic pathway 62 Genetic predisposition 62 TOP2A 62 alpha synuclein gene 62 Epidemiologic studies 62 fatty acid synthase 62 HLA DQ2 62 extramedullary 62 impaired insulin secretion 62 GABRA2 62 endothelial activation 62 Heritability 62 BRCA1 mutations 62 clinicopathologic 62 Multivariate logistic regression 62 adiponectin levels 62 acute humoral rejection 62 substrate specificity 62 neurocognitive impairment 62 signaling cascades 62 TMEM#B 62 MAPK pathway 62 p# mutations 62 atherogenesis 62 TMPRSS2 ERG 62 microdeletion 62 serum GGT 62 IKZF1 62 proband 62 NSCLC tumors 62 pharmacodynamic biomarkers 62 SORL1 gene 62 autonomic dysfunction 62 COL#A# 62 PCa 62 cyclin E 62 isotypes 62 prognostic indicator 62 microglial 62 ESR1 62 somatostatin 62 noncoding RNAs 62 GRNCM1 62 glucocorticoid receptors 62 phenotypic expression 62 PTEN gene 62 prenatal exposures 62 nonalcoholic steatohepatitis NASH 62 CNTNAP2 62 unmeasured confounders 62 HepG2 cells 62 cardiac biomarkers 62 antiangiogenic therapy 62 LIS1 62 histologic subtypes 62 metabolic parameters 62 murine model 62 p# MAPK 62 histone acetylation 62 metabolic enzymes 62 APOE gene 62 Li Fraumeni 62 HG PIN 62 MDR1 62 genes predisposing 62 mitochondrial mutations 62 GPC5 62 autoantigen 62 gastric adenocarcinoma 62 transgenic mouse model 62 serotonin receptor 62 NOD2 62 univariate analyzes 62 #p# [003] 62 antiphospholipid antibodies 62 genetic syndromes 62 HER2 overexpression 62 dysregulation 62 phenotypic variation 62 CHEK2 62 breast cancer subtypes 62 #q# [002] 62 biomarker 62 prothrombotic 62 C1q 62 epithelial tumors 62 penetrance 62 chromosome #p# [001] 62 epistasis 62 molecular mechanisms underlying 62 cardiometabolic disorders 62 MAP#K# 62 DARPP 62 EBV infection 62 STAT4 62 type2 diabetes 62 APOE ε4 62 heterozygotes 62 TSC1 62 ABL1 62 lymphangiogenesis 62 UGT#A# * 62 pathophysiologic mechanism 62 eicosanoids 62 carcinoembryonic antigen 62 p# activation 62 GSTT1 62 thyrotropin levels 62 biochemical markers 62 KCNH2 62 gastric carcinogenesis 62 peptide antigens 62 elevated triglyceride levels 62 Cytochrome P# 62 apoptotic pathway 62 systemic inflammation 62 Nordestgaard 62 myeloproliferative neoplasms 62 5 HT1A 62 KIF6 gene 62 cathepsins 62 GSTM1 62 experimentally induced 62 induced sputum 62 Alpha synuclein 62 pharmacologic intervention 62 LV dysfunction 62 testicular germ cell 62 PICALM 62 LDL receptor 62 CDKN2A 62 receptor gamma 62 intestinal microbiota 62 E#F# 62 muscular dystrophies 62 elevated CRP 62 vascular dysfunction 62 C#Y 62 epigenetically 62 TRAF1 C5 62 sphingolipid 62 HLA molecules 62 sphingolipids 62 androgen receptor AR 62 Fas ligand 62 periodontal pathogens 62 microcephalin 62 TPMT 62 Cognitive impairment 62 HLA DR4 62 PPAR γ 62 hereditary hemochromatosis 62 RIP1 61 plasma pharmacokinetics 61 myelofibrosis polycythemia vera 61 #p#.# [002] 61 basal cell nevus syndrome 61 paraneoplastic 61 haplotypes 61 plasma lipids 61 fibrate drugs 61 metastatic lymph nodes 61 mitochondrial dysfunction 61 causative mutations 61 small molecule activators 61 NAT2 61 inducible nitric oxide synthase 61 selective antagonists 61 FLT3 61 esophageal squamous cell carcinoma 61 logistic regression analysis 61 chromosome #q# [002] 61 metabolic abnormality 61 FGFR1 61 serum lipids 61 podocyte 61 serum antibodies 61 tumor hypoxia 61 cTnT 61 cAMP signaling 61 sequence homology 61 chemosensitivity 61 NPY gene 61 folate metabolism 61 Epstein Barr Virus EBV 61 mutational analysis 61 conditional logistic regression 61 lipid metabolism 61 hormone aldosterone 61 Smad3 61 thyroid dysfunction 61 ConclusionThis 61 anemias 61 spontaneous mutations 61 homozygotes 61 V#F mutation 61 tumor histology 61 polycythemia vera PV 61 confounders 61 EGFR blockers 61 glial tumors 61 haplogroups 61 carotid plaque 61 tumorigenicity 61 biological pathways 61 AT1R 61 urothelial cancer 61 TLE3 61 HNSCC 61 macrovascular disease 61 protein conformation 61 IGF IR 61 KRAS mutation 61 genetic markers 61 chromosome #q#.# [001] 61 Epidermal Growth Factor Receptor 61 PCA3 gene 61 NOMID 61 APOE4 61 promoter polymorphism 61 P#X# receptor 61 prognostic factors 61 BMP2 61 calcium homeostasis 61 KRAS mutation status 61 TNFalpha 61 TMPRSS2 ERG fusion 61 anti fibrotic 61 nicotinic receptor 61 molecular pathways 61 subcellular localization 61 univariate 61 EGFR tyrosine kinase inhibitors 61 remnant lipoproteins 61 antidepressant efficacy 61 potent inhibitors 61 CEACAM1 61 lymphoma subtypes 61 microRNA molecules 61 Predisposition 61 metabolic disturbances 61 TT genotype 61 tumor subtype 61 alpha synuclein protein 61 gene amplification 61 promoter methylation 61 clinico pathological 61 CYP#B# 61 haematopoietic 61 cell adhesion molecule 61 EGFR inhibition 61 ataxias 61 circadian clock genes 61 mutational status 61 transgenic mouse models 61 coinfected patients 61 MRSA isolates 61 MLH1 61 genetic mutations 61 cytogenetic abnormalities 61 dopamine transporter gene 61 longitudinal cohort study 61 differentially expressed proteins 61 supratentorial 61 subclinical 61 immunoregulatory 61 logistic regression analyzes 61 metabolic alterations 61 outer membrane proteins 61 transthyretin 61 genomewide association studies 61 obstructive coronary 61 LPA gene 61 electrophysiologic 61 myeloproliferative disorders 61 serum concentrations 61 neuropathological 61 previously uncharacterized 61 euthymic patients 61 HLA B# 61 S#A# [002] 61 MR spectroscopy 61 activating mutation 61 KCNQ1 61 normal karyotype 61 genotype phenotype 61 antiproliferative effects 61 molecular underpinnings 61 mammographic density 61 non coding RNA 61 silent myocardial ischemia 61 SNPs 61 intronic 61 splice junctions 61 lymphoid cells 61 SIBO 61 mRNA transcripts 61 familial predisposition 61 atherosclerotic lesions 61 cerebral infarction 61 TNF α 61 XMRV infection 61 HMGA1 61 gastric carcinomas 61 MetAP2 61 epithelial barrier 61 ALK gene 61 PB1 F2 61 HNPCC 61 causal pathway 61 causative mutation 61 hepatotoxicity 61 alleles 61 GRP# 61 leiomyomas 61 secreted protein 61 endogenous opioid 61 sonographic appearance 61 allelic 61 Glucocorticoids 61 serum markers 61 gene mutations 61 immunohistochemical staining 61 Autoantibodies 61 neuroimaging studies 61 Hypothalamic 61 MEF2A 61 cardiac channelopathies 61 airway remodeling 61 kinase inhibition 61 carcinoid 61 KIF6 gene variant 61 RUNX3 61 microvascular disease 61 C. trachomatis 61 physiologic mechanisms 61 shorter telomere length 61 Genetic Variation 61 SLC#A# gene [001] 61 Serum concentrations 61 quasispecies 61 predictive biomarker 61 pathogenetic mechanisms 61 genotype 61 adenomatous 61 primary biliary cirrhosis 61 metastatic neuroendocrine tumors 61 transthyretin amyloidosis 61 microsatellite instability 61 BRCA1 BRCA2 61 gene APOE 61 N glycan 61 Logistic regression analysis 61 genotypes 61 confounder 61 cardiac conduction 61 PTEN protein 61 plasminogen 61 ultrastructural 61 developmental neurotoxicity 61 vascular endothelial 61 gut microbiota 61 iNOS 61 Genetic mutations 61 lung epithelium 61 EGFR HER2 61 folate deficiency 61 Protein Kinase C 61 IGFBP2 61 mutated K ras 61 SH#B# 61 gefitinib Iressa 61 VHL gene 61 cardiolipin 61 MC1R 60 molecular determinants 60 COX enzymes 60 GABAB receptors 60 BRCA2 carriers 60 HLA alleles 60 cardiac troponin 60 glutamic acid decarboxylase 60 MECP2 gene 60 ApoE 60 mucins 60 pathogenic mutations 60 torsade de pointes 60 selective inhibition 60 HPA axis 60 MLL2 60 thromboembolic complications 60 multigene 60 methylenetetrahydrofolate reductase 60 cryptogenic 60 microbleeds 60 psychosocial variables 60 micro RNA 60 bronchopulmonary dysplasia BPD 60 abnormal glucose metabolism 60 β amyloid 60 neuroinflammation 60 miRs 60 Leukemias 60 G allele 60 ovarian hormones 60 urolithiasis 60 HER2 HER3 60 ATTR CM 60 JAK mutations 60 VIPR2 60 STK# [002] 60 fronto temporal dementia 60 CP CPPS 60 NKG2D 60 nNOS 60 receptor inhibitor 60 antiphospholipid syndrome 60 myeloperoxidase 60 eotaxin 60 glomerular 60 catechol O methyltransferase 60 neurologic complications 60 Cathepsin B 60 intestinal polyps 60 susceptibility alleles 60 serotonin transporter 60 subclinical hyperthyroidism 60 Prognostic factors 60 amyloid cascade 60 sortilin 60 paralogs 60 adrenal cortex 60 Dysregulation 60 indels 60 residual confounding 60 oxidized phospholipids 60 NKX#.# 60 breast cancer genes BRCA1 60 genetic variant 60 epigenetic modification 60 vitamin D receptors 60 HBeAg negative 60 FCGR3A 60 assay detects 60 subtype selective 60 DQB1 * 60 nucleotide substitutions 60 APOC3 60 vitro experiments 60 fetuin 60 chemokine receptor 60 prolonged QT interval 60 Fc gamma receptor 60 signaling pathways 60 transient elastography 60 androgen receptor gene 60 KRAS status 60 QTc prolongation 60 skeletal metastases 60 neuropsychiatric diseases 60 Galectin 3 60 podocytes 60 elevated homocysteine 60 PAR1 60 histologic subtype 60 gene fusions 60 coagulation abnormalities 60 inherited predisposition 60 MMP inhibitors 60 B7 H3 60 multi factorial disease 60 monozygotic twin 60 increased intestinal permeability 60 cholesterol metabolism 60 CD# expression [001] 60 Darapladib 60 androgen deficiency 60 Skeletal muscle 60 dysbindin 60 incidentalomas 60 NR#A# 60 myo inositol 60 diabetes mellitus DM 60 protein tyrosine phosphatase 60 HLA genes 60 trans retinoic acid 60 IDH1 60 mGluR5 antagonist 60 lung adenocarcinoma 60 mesothelin 60 cervical lymph nodes 60 SORL1 60 TNFR1 60 hypercalciuria 60 tyrosine phosphorylation 60 homodimers 60 papillary renal cell carcinoma 60 ribosomal protein 60 genetic underpinnings 60 AMACR 60 JAK2 60 psychobiological 60 mitochondrial metabolism 60 chorioamnionitis 60 microbiota 60 nucleotide sequence 60 genes encoding 60 Epstein Barr virus EBV 60 M. pneumoniae 60 AAT deficiency 60 p tau 60 LVNC 60 multivariate Cox 60 behavioral disinhibition 60 bronchial epithelial cells 60 karyotypes 60 hyperacute 60 activin 60 unmeasured confounding 60 sarcosine 60 Homocysteine 60 CTEPH 60 hypoxic tumors 60 oxidases 60 apolipoprotein E 60 PDE#A 60 genomewide association study 60 Angiotensin converting enzyme 60 fasting plasma 60 PDGF receptor 60 CXCL5 60 Mesothelin 60 TP# mutation 60 cardiomyopathies 60 intact parathyroid hormone 60 Brain derived neurotrophic 60 CD# expression [002] 60 MMP# 60 liver metastasis 60 kallikrein 60 diabetic kidney 60 NFTs 60 B7 H4 60 chromosomal translocations 60 clefting 60 FGFR3 60 Single Nucleotide Polymorphisms SNPs 60 HERmark assay 60 familial ALS 60 PI3K AKT 60 receptor gene 60 bone scintigraphy 60 gastric cardia 60 transcriptional activation 60 pharmacodynamic markers 60 antioxidant supplementation 60 ADRB2 60 Activating mutations 60 deCODE AF TM 60 metaplasia 60 leptin deficiency 60 amino acid substitutions 60 TGF ß 60 biologic plausibility 60 carotid bruit 60 miRNA expression patterns 60 transcriptional regulation 60 covariate 60 hematological parameters 60 pDCs 60 Autoimmune disorders 60 ERalpha 60 UCRs 60 Genotypic 60 IgG antibody 60 Cystatin C 60 orthologs 60 IGFBP 60 WT1 60 T1DM 60 Brugada Syndrome 60 bivariate analyzes 60 transgenic mice expressing 60 serine protease 60 ductal carcinomas 60 melatonin receptor 60 R#W [002] 60 thyroglobulin 60 HER2 amplification 60 cardioprotective effect 60 histone methylation 60 virulence determinants 60 etiologic agent 60 nonischemic 60 microRNA miR 60 posttranslational modifications 60 ALI ARDS 60 isoenzymes 60 retrospective cohort 60 transgene expression 60 comorbid depression 60 caveolae 60 hyperinsulinemia 60 neurexins 60 prognostically 60 hyperplastic 60 BMPR2 60 autosomal dominant polycystic kidney 60 proteomes 60 polymorphism 60 cTnI 60 humanin 60 sonographic diagnosis 60 Treg cell 60 TTR gene 60 adiponectin 60 LDL particle 60 clinicopathological features 60 immune dysregulation 60 Dr. Pasinetti 60 PI3K pathway 60 IL 1β 60 molecular markers 60 isotype 60 HBV genotypes 60 adenocarcinomas 60 neurological abnormalities 60 chlamydial 60 oligodendrogliomas 60 microarray experiments 60 Wwox 60 clade B 60 bone metabolism 60 KCNE2 60 Teriflunomide 60 untreated celiac disease 60 synovial tissue