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(Click for frequent words.) 72 gene expression 70 DNA methylation 68 methylation 68 epigenetics 66 chromatin structure 66 molecular pathways 65 epigenetic changes 65 genes 65 histone modifications 65 alternative splicing 65 epigenetic alterations 64 gene 64 histone modification 63 Epigenetic 63 genomic imprinting 63 gene mutations 63 microRNAs 62 acetylation 62 epigenetic modification 62 epigenome 62 tumor suppressor genes 62 imprinted genes 62 stem cell differentiation 62 SIRT3 62 Wnt signaling 62 miRNA expression 62 epigenetic modifications 62 protein kinases 62 microRNAs miRNAs 62 metabolic enzymes 62 hypermethylation 62 miRNA 61 LIS1 61 genetic 61 evolutionarily conserved 61 epigenetic mechanisms 61 transcription factors 61 microRNA expression 61 transcriptional regulation 61 miRNAs 61 signaling pathways 61 gene transcription 61 proteins 61 epigenetic regulation 61 chromatin 61 molecular 61 genetic mutations 61 micro RNAs 61 mutations 61 tyrosine kinases 61 genomic 60 tumor suppressor gene 60 GPR# [002] 60 methylation patterns 60 CFTR gene 60 synaptogenesis 60 p# gene 60 mitochondrial dysfunction 60 cell signaling pathways 60 chromosomal instability 60 kinase 60 histone 60 Wnt pathway 60 ubiquitination 60 Wnt signaling pathway 60 HOTAIR 60 signaling pathway 60 DNA methylation patterns 60 neurodegeneration 60 molecular pathway 60 genes encoding 60 5 hydroxymethylcytosine 60 beta catenin 60 JAK2 60 metabolic 60 noncoding RNAs 60 signal transduction 59 intracellular proteins 59 tumor suppressor protein 59 protein synthesis 59 carcinogenesis 59 histone methylation 59 tumorigenesis 59 DISC1 59 mutated gene 59 mutated genes 59 alternatively spliced 59 WT1 59 FOXO3a 59 regulates gene expression 59 p# protein 59 SGK1 59 Skp2 59 mitochondrial 59 transcriptional 59 epigenetic marks 59 Src 59 NFkB 59 Foxp3 59 biological pathways 59 membrane fusion 59 synapse formation 59 apoE 59 PTPN# 59 gene expression patterns 59 glutamate receptor 59 epigenetically 59 sirtuins 58 biochemical mechanisms 58 JAK STAT 58 glycosylation 58 transcriptional repressor 58 small RNAs 58 molecular mechanisms 58 proto oncogene 58 STAT4 58 Notch pathway 58 Hedgehog pathway 58 signaling molecule 58 piRNAs 58 actin cytoskeleton 58 microRNA molecules 58 metabolic pathways 58 genetic abnormalities 58 neuronal migration 58 chromosomal 58 lipid metabolism 58 genomic instability 58 serotonin receptor 58 neuroendocrine 58 FOXO 58 cystic fibrosis transmembrane conductance 58 molecular mechanism 58 mRNAs 58 ERK signaling 58 miR #a [002] 58 HBx 58 genetic variations 58 micro RNA 58 protein misfolding 58 mTOR signaling 58 cellular pathways 58 MECP2 gene 58 pre mRNA splicing 58 Sox9 58 glutamate receptors 58 biochemical pathway 58 chromosomal translocations 57 microRNA 57 mtDNA mutations 57 chromatin remodeling 57 VIPR2 57 non coding RNA 57 histone acetylation 57 morphogens 57 alpha synuclein 57 JAK2 enzyme 57 Hh pathway 57 molecular abnormalities 57 tau protein 57 Six3 57 Myc 57 MDM2 57 ubiquitylation 57 circadian clock genes 57 Epigenetics 57 SIRT1 57 phosphatases 57 epigenetic silencing 57 protein phosphorylation 57 mutation 57 microglial 57 neural crest 57 LRRK2 57 histone deacetylases 57 mutant genes 57 cellular metabolism 57 phenotype 57 epigenomic 57 kinases 57 chromosomal rearrangements 57 regulate gene expression 57 MicroRNA 57 epigenetic markers 57 Smad3 57 telomere dysfunction 57 CYP#D# gene 57 apoE4 57 MTHFR 57 NF kappa B 57 oncogenesis 57 progerin 57 LRRK2 gene 57 HSF1 57 hedgehog pathway 57 miR #b [002] 57 somatic mutations 57 CCR3 57 c myc 57 costimulatory 57 epigenetic inheritance 57 transcriptional activation 57 malignant transformation 57 SCD1 57 KIAA# 57 estrogen receptor alpha 57 ALK gene 57 RNA molecules 57 FGFs 57 MeCP2 57 oncogenic 57 huntingtin protein 57 TMEM#B 57 aldehyde dehydrogenase 57 tyrosine phosphorylation 57 LDL receptor 56 Hox gene 56 miRNA genes 56 receptor gamma 56 biochemical 56 p# activation 56 oncogenes 56 non coding RNAs 56 alpha synuclein gene 56 protein tyrosine phosphatases 56 RNA splicing 56 p#/CBP 56 DARPP 56 Genetic variations 56 tumor suppressors 56 calcineurin 56 breast cancer metastasis 56 cholesterol metabolism 56 PIK3CA 56 peroxisome 56 membrane protein 56 palladin 56 LKB1 56 beta1 integrin 56 BARD1 56 inhibitory 56 genotoxic stress 56 neurogenesis 56 protein kinase C 56 SIRT1 gene 56 neurofibrillary tangles 56 cyclin D1 56 genetic variation 56 cell motility 56 transcription factor 56 GSK3 56 Clusterin 56 Methylation 56 airway remodeling 56 p# pathway 56 sirtuin 56 Hedgehog signaling pathway 56 kinase pathway 56 MAPK pathway 56 signaling cascades 56 riboswitches 56 H#K# [002] 56 BMP signaling 56 RhoA 56 Rb gene 56 neuronal degeneration 56 immunological 56 sphingolipid 56 synaptic function 56 pathophysiological 56 Fragile X gene 56 tumor microenvironment 56 posttranslational modifications 56 epigenomes 56 aneuploidy 56 deacetylation 56 nucleosome 56 FGFR2 56 gene rearrangements 56 protein encoded 56 DNMT1 56 RNAs 56 susceptibility genes 56 neuronal 56 genetic susceptibility 56 p# [001] 56 DLX5 56 SH2 B 56 IGF2 56 NF kappaB 56 pRb 56 maternally inherited 56 Polycomb proteins 56 gene mutation 56 p# MAPK 56 transgenic mouse model 56 Rho GTPases 56 cypin 56 Pten 56 adult neurogenesis 56 Notch signaling 56 cyclins 56 biochemical pathways 56 Alu elements 56 neuronal differentiation 56 PTP1B 55 c Myc 55 phenotypic expression 55 lipid synthesis 55 causative genes 55 histone code 55 TGF β 55 PTEN gene 55 IGF1 55 mitochondrial mutations 55 microcephalin 55 biogenesis 55 DNA rearrangements 55 germ cells 55 LRP5 55 Hedgehog signaling 55 MDSCs 55 genomewide 55 VEGF receptor 55 innate immunity 55 secretory pathway 55 cell signaling pathway 55 autoimmunity 55 Kv#.# 55 FGFR3 55 genetically encoded 55 CYP#C# [002] 55 chromosomal regions 55 hippocampal function 55 CNVs 55 phenotypic 55 KLF4 55 ribosomal proteins 55 MEF2 55 sRNA 55 axon guidance 55 neuroligins 55 podocyte 55 mitogen activated protein kinase 55 mitochondria 55 gene locus 55 MECP2 55 protein conformation 55 glucocorticoid receptor 55 casein kinase 55 PPARγ 55 Cdc# 55 germline mutations 55 Rb#/p# 55 FMR1 gene 55 selective inhibition 55 pleiotropic 55 molecular mechanisms underlying 55 vimentin 55 proteolysis 55 protein kinase 55 Id1 55 polyamines 55 topoisomerases 55 druggable target 55 mutated protein 55 NMDA receptor 55 tumor suppressor 55 chromatin modifications 55 receptor gene 55 demethylating 55 heterochromatin 55 NF1 gene 55 chloroplasts 55 ERBB2 55 ribosomal genes 55 tRNA synthetase 55 X inactivation 55 gut microbiota 55 TAp# 55 calcium homeostasis 55 neuromuscular junction 55 oncogene 55 melanocyte 55 ERK pathway 55 p# mutations 55 DNA hypermethylation 55 missense mutations 55 mutant gene 55 genetic variants 55 serotonin transporter 55 meiotic recombination 55 lincRNAs 55 chromosomal rearrangement 55 CALHM1 55 germline cells 55 BRAF gene 55 neuropsychiatric diseases 55 phosphorylation 55 E3 ubiquitin ligase 55 CHD7 55 gut microbes 55 beta globin gene 55 coding RNA 55 messenger RNAs mRNAs 55 genetic alterations 55 PPAR gamma 55 mammalian cells 55 transcriptional repression 55 FGFR1 55 proteases 55 RNAi pathway 55 BMP4 55 suppressor gene 55 STAT3 55 receptor molecule 55 PINK1 55 medulloblastomas 55 IKK beta 55 S#K# 55 estrogen metabolism 55 adipogenesis 55 Hfq 55 MAPK 55 cis regulatory 55 HOX genes 55 P#X# 54 polymorphisms 54 LMNA gene 54 regulating gene expression 54 miR 54 hedgehog signaling 54 EGFR pathway 54 Treg cell 54 NFκB 54 C. elegans 54 Cyclin D1 54 mutant protein 54 Pax6 54 sortilin 54 GRP# 54 intracellular signaling 54 somatic mutation 54 dopamine transporter 54 protein 54 PDGFR 54 NRG1 54 RNA silencing 54 chromosomal aberrations 54 Sox2 54 Aβ 54 neuronal dysfunction 54 KLF# 54 transcriptional coactivator 54 homeobox gene 54 oxidase 54 proteostasis 54 GABAergic 54 intracellular signal transduction 54 Wnt proteins 54 estrogen receptor 54 HDAC 54 neurite outgrowth 54 DNA methyltransferases 54 ion channel 54 CNTNAP2 54 misfolding 54 HDACs 54 polyadenylation 54 tumorigenic 54 H#K# methylation 54 podocytes 54 TCF#L# gene 54 ubiquitin ligase 54 Smoothened 54 microdeletions 54 Dysregulation 54 NF κB 54 transcriptome 54 TGF b 54 NFAT 54 FoxO1 54 p# tumor suppressor 54 ribonucleic acids 54 neuronal plasticity 54 γ secretase 54 SOD1 54 phenotypes 54 stem cell pluripotency 54 radial glia 54 clusterin 54 inherited mutations 54 peroxisome proliferator activated 54 Akt 54 granule cells 54 histone H3 54 single nucleotide polymorphism 54 chloroplast 54 neurofibromin 54 huntingtin 54 ubiquitin ligases 54 Oct4 54 ubiquitin 54 PKMzeta 54 SOD1 gene 54 PKM2 54 breast cancer genes BRCA1 54 Sonic Hedgehog 54 SRY gene 54 receptor protein 54 modulatory 54 mRNA 54 mTOR pathway 54 cyclin dependent kinases 54 biosynthesis 54 androgen receptor 54 noncoding RNA 54 RNA polymerase II 54 Kinases 54 TSLP 54 microdeletion 54 tropomyosin 54 melanocortin receptors 54 brain neurochemistry 54 post transcriptional 54 drug metabolizing enzymes 54 BRCA1 gene 54 Wnt#b 54 transcriptional machinery 54 synaptic plasticity 54 Jhdm2a 54 histones 54 ERK1 2 54 ribonucleic acid RNA 54 neural crest cells 54 genetic polymorphism 54 endoplasmic reticulum stress 54 neuronal cell 54 immunoregulatory 54 DNA demethylation 54 adipogenic 54 NKG2D 54 FGF# 54 neurodegenerative disease 54 chromosome condensation 54 Chromosomal 54 presenilin 54 PPARg 54 telomere maintenance 54 ARID1A 54 Hox genes 54 4E BP1 54 IDH1 54 substrate specificity 54 Histone 54 Myostatin 54 Notch1 54 E3 ligase 54 MLH1 54 TORC2 54 myeloid cells 54 Genetic variation 54 apoptotic 54 neuroinflammation 54 sporadic ALS 54 BMAL1 54 activin 54 prodynorphin 54 MAP kinase 54 TLR4 54 LRP6 54 cellular signaling pathways 54 mammalian 54 perilipin 54 PI3 kinase 54 potent inhibitors 54 DNA replication 54 synaptic transmission 54 protein p# 54 endogenous ligands 54 SMN1 54 hypoxia inducible factor 54 BubR1 54 quantitative trait loci 54 centrosome 54 RNA polymerases 54 OCT4 54 Ras pathway 54 BCL#A 54 PARP inhibition 54 Dpp 54 genetic underpinnings 54 EGFR signaling 54 MSH2 54 UTRs 54 IRF5 54 placental function 54 nucleolar dominance 54 phytochrome 54 progranulin 54 Akt1 54 PICALM 54 cytokine 54 glucocorticoid receptor GR 54 caspases 54 mitochondrial function 53 virulence genes 53 retinoic acid 53 genomic alterations 53 overexpression 53 TGF beta 53 germline 53 genes CYP#C# 53 telomere shortening 53 mutant huntingtin protein 53 primary cilia 53 PI3K pathway 53 budding yeast 53 MLL2 53 regulated kinase ERK 53 induce apoptosis 53 p#INK#a 53 GAB2 53 endogenous 53 APOE4 53 Akt signaling 53 transgene expression 53 colorectal carcinogenesis 53 recessive trait 53 lipoprotein metabolism 53 uPAR 53 TP# gene 53 genetic recombination 53 enzyme 53 multigenic 53 cellular senescence 53 Rev erb 53 kinase domain 53 H#K# [001] 53 mitochondrial proteins 53 Signal transduction 53 CYP#E# 53 DRD2 gene 53 nucleotide 53 neurotransmission 53 DLC1 53 misregulation 53 cytoskeletal 53 mitochondrial gene 53 underlying molecular mechanisms 53 FOXP3 53 HDAC inhibitors 53 beta amyloid plaques 53 microglial activation 53 CNTNAP2 gene 53 homologous recombination 53 intracellular 53 calpain 53 SATB1 53 adipocyte 53 sumoylation 53 clefting 53 ADAM# 53 ectopic expression 53 chromosomal abnormalities 53 MAPKs 53 oxidative phosphorylation 53 ABCA1 53 molecular signaling pathway 53 transdifferentiation 53 RNase L 53 proapoptotic 53 gene variants 53 oncoprotein 53 mRNA expression 53 small molecule inhibitors 53 FGF signaling 53 RUNX3 53 protein tau 53 gene amplification 53 tyrosine kinase 53 mitosis 53 H#K#me# 53 gene p# 53 molecular underpinnings 53 proteins encoded 53 ADDLs 53 FASPS 53 de novo mutations 53 molecular biomarkers 53 mutant huntingtin 53 Nedd4 53 SIRT2 53 OGG1 53 pharmacogenetic 53 aberrant methylation 53 beta amyloid peptides 53 BCR ABL 53 FTLD 53 X chromosome 53 HDAC2 53 #beta HSD1 53 c Myb 53 NR2B 53 E cadherin 53 hepatocyte 53 phenotypic variability 53 FGF2 53 Th2 53 β catenin 53 IKZF1 53 SORL1 53 PALB2 53 signaling cascade 53 cell adhesion molecules 53 TCF#L# 53 glutamate signaling 53 environmental toxicants 53 Htt 53 transduce 53 BRAF protein 53 transmembrane receptor 53 PKC isoforms 53 glial 53 intestinal epithelium 53 Runx1 53 TOP2A gene 53 morphogen 53 mutational 53 Cdk5 53 COMT gene 53 mutant proteins 53 metazoan 53 HGPS 53 fatty acid synthesis 53 phosphorylates 53 COX enzymes 53 Transcriptional 53 thrombospondin 53 matrix metalloproteinases 53 neuronal function 53 TSC1 53 aromatase 53 ERK2 53 ras gene 53 Helicobacter 53 catenin 53 TIR1 53 isoform 53 C EBP alpha 53 antiapoptotic 53 glycoproteins 53 Aurora kinases 53 huntingtin gene 53 epithelial cell 53 SMAD4 53 IL#R 53 Bcl 2 53 CHI#L# 53 dysregulation 53 dopaminergic 53 biochemical processes 53 ErbB 53 MicroRNAs 53 molecular chaperones 53 Th1 53 FLT3 53 paxillin 53 IFRD1 53 COUP TFII 53 neuronal circuits 53 Kinase 53 downregulation 53 oligomeric 53 IL 1beta 53 autism susceptibility genes 53 ncRNA 53 E#F# 53 V#F mutation 53 carbohydrate metabolism 53 paralogs 53 overactivation 53 beta amyloid peptide 53 neurochemical 53 BRCA1 53 molecularly targeted 53 5 methylcytosine 53 Prox1 53 EZH2 53 NFKBIA 53 signal transduction pathways 53 chaperone proteins 53 PP2A 53 dysbindin 53 epigenetic reprogramming 53 genetic imprinting 53 cystic fibrosis transmembrane 53 receptor proteins 53 HLA genes 53 mTOR 53 conformational changes 53 mitochondrial enzyme 53 Tregs 53 RAR beta 53 GPCRs 53 mRNA splicing 52 serine protease 52 tumor angiogenesis 52 Fibroblast Growth Factor Receptor 52 evolutionary conserved 52 chromosomal translocation 52 tumor suppressor p# 52 NF1 52 GPx 52 CB2 receptor 52 noncoding 52 spontaneous mutation 52 primordial germ cells 52 sequence homology 52 chromosomes 52 neurotransmitter glutamate 52 FANCD2 52 NF kB pathway 52 Ago2 52 metabolic processes 52 PAR1 52 SMN2 52 TGF beta pathway 52 epithelial mesenchymal transition 52 cytosine methylation 52 mRNA molecules 52 KRAS oncogene 52 MC4R gene 52 TFIIH 52 HIF 1alpha 52 fruitflies 52 Notch receptor 52 MAPK signaling pathway 52 glycogen synthase kinase 52 Thyroid hormones 52 sphingolipids 52 hepatic stellate cells 52 retinoblastoma protein 52 VHL gene 52 SLC#A# [001] 52 Hsp# [001] 52 HMGA2 52 demethylation 52 serine threonine 52 enzymatic activity 52 Raf MEK ERK 52 intracellular signaling pathways 52 serine threonine kinase 52 rRNA 52 NMDA receptors 52 apoptosis 52 CTLA 4 52 cellular organelles 52 FMR1 52 nicotinic receptor 52 spontaneous mutations 52 SWI SNF 52 XBP1 52 motor neuron degeneration 52 chromosome #q# [002] 52 protein homeostasis 52 PRDM# 52 mRNA decay 52 gene silencing 52 modulate gene expression 52 RANKL 52 Wnt1 52 cohesin 52 lysosomal storage diseases 52 heritable 52 neoplastic transformation 52 estrogen receptor beta 52 activating mutations 52 cathepsins 52 methyltransferases 52 MC1R 52 chromosomal DNA 52 genetic mutation 52 polyamine 52 neuropsychiatric disorders 52 Nrf2 52 S#A# [002] 52 muscular dystrophies 52 mesenchymal cell 52 TRPV3 52 fatty acid synthase 52 telomere length 52 retinoblastoma Rb 52 laforin 52 conformational 52 NS5A 52 haematopoietic 52 eukaryotic 52 #q# [001] 52 SORL1 gene 52 pathophysiologic 52 MAP kinases 52 lysosomal 52 gamma H2AX 52 telomere 52 TGF ß 52 netrin 1 52 Sir2 52 molecular signaling pathways 52 Sonic hedgehog 52 tumor suppressive 52 renal fibrosis 52 Symadex 52 neurodegenerative diseases 52 rDNA 52 ALK mutations 52 SCN5A 52 membrane proteins 52 HCV replication 52 HbF 52 xenobiotic 52 neural precursor 52 Cdc7 52 suppressor genes 52 MDMX 52 neuroligin 52 promoter hypermethylation 52 FOXP2 52 familial ALS 52 forkhead 52 PcG 52 habenula 52 cryptochromes 52 messenger RNAs 52 miR #b [001] 52 MLL gene 52 postsynaptic 52 estrogen receptors 52 hippocampal neurons 52 macrophage activation 52 functional polymorphism 52 biologic pathways 52 signaling molecules 52 metazoans 52 neurexin 52 EGFR 52 mesenchymal 52 hematopoiesis 52 Wnt beta catenin 52 gene expression profiles 52 nicotinic receptors 52 untranslated regions 52 circadian 52 BRCA2 gene 52 acetyl groups 52 pathogenesis 52 cyclin B1 52 antitumor 52 misfolded protein 52 ligases 52 inosine 52 FGFR 52 S1P 52 SIR2 52 folate metabolism 52 TLRs 52 endocannabinoid system 52 allosteric 52 mitochondrial fusion 52 CEACAM1 52 hormone leptin 52 neurobiological 52 ion channels 52 ß catenin 52 Hh 52 MAP kinase pathway 52 Brd4 52 cdk5 52 GABAergic neurons 52 Wnt 52 mitogen activated protein 52 STK# [002] 52 major histocompatibility complex 52 PDE#A 52 HIF 1a 52 eukaryotic cells 52 NF kB 52 transient receptor 52 E1A 52 histone proteins 52 myelination 52 cAMP 52 LMNA 52 superoxide dismutase 52 GABAB receptors 52 meiotic 52 messenger RNA 52 immunodominant 52 caveolin