Related by context. All words. (Click for frequent words.) 74 dysregulation 71 neuroendocrine 71 ERK signaling 71 Dysregulation 70 neuronal dysfunction 70 muscarinic receptors 69 neuroinflammatory 69 upregulates 68 protein kinase C 68 overactivity 68 IL 1β 68 lysosomal 68 overactivated 68 glutamate receptors 68 autocrine 68 HPA axis 68 synaptic transmission 67 TGF b 67 hyperactivation 67 podocyte 67 dopaminergic 67 AMPA receptor 67 circadian clock genes 67 hypothalamic 67 glutamatergic 67 autophagic 67 extracellular signal 67 inhibitory neurotransmitters 67 hyperinsulinemia 67 p# activation 67 induce apoptosis 67 noradrenergic 67 deacetylation 67 proto oncogene 67 MAP kinase 67 sortilin 67 AT1R 66 regulated kinase ERK 66 excitatory neurotransmitter 66 Smad3 66 ABCA1 66 downregulation 66 neurotransmission 66 mesolimbic 66 adrenal cortex 66 mutant huntingtin protein 66 neurotrophic 66 carbohydrate metabolism 66 ENaC 66 regulates gene expression 66 phosphatidylinositol 3 66 histone deacetylases 66 pRb 66 mineralocorticoid 66 catenin 66 potent inhibitors 66 Angiotensin II 66 proinflammatory 66 mitogen activated protein kinase 66 c MET 66 overactivation 66 galanin 66 β catenin 66 PDGFR 66 potent inhibition 66 synaptogenesis 66 hormone secretion 66 POMC neurons 66 androgen receptor AR 66 dopamine signaling 66 eNOS 66 upregulate 66 mGluR 66 TMEM#B 66 hypothalamic pituitary adrenal axis 66 metabolic abnormalities 65 somatostatin 65 caveolin 65 Notch signaling 65 NADPH oxidase 65 gluconeogenesis 65 TXNIP 65 endocannabinoid signaling 65 receptor subtype 65 neuronal differentiation 65 phosphatases 65 TLR4 65 PI3K pathway 65 inverse agonist 65 signaling cascades 65 adult neurogenesis 65 serotonin receptor 65 basal forebrain 65 factor BDNF 65 neuroinflammation 65 LRP5 65 TRPV4 65 upregulating 65 RIP1 65 NR2B 65 neuromuscular junction 65 MAPK pathway 65 palmitoylation 65 cytokine signaling 65 Macrophage 65 PTPN# 65 anti inflammatory cytokine 65 PPARg 65 Akt signaling 65 underlying pathophysiology 65 serine proteases 65 PON1 65 Phosphorylation 65 leptin signaling 65 ERK1 2 65 acetylcholine receptor 65 FGF2 65 serotonergic 65 apoptotic pathway 65 5 HT1A 65 NKG2D 65 LKB1 65 Clusterin 65 tyrosine phosphorylation 65 N methyl 65 neurotransmitter glutamate 65 glucocorticoid receptor 65 beta amyloid peptide 65 excitatory neurotransmitter glutamate 65 PTEN gene 65 TGF ß 65 NKX#.# 65 UCP2 65 PTH secretion 65 endocannabinoid system 65 NOD2 65 glucose homeostasis 65 aberrant activation 65 Treg cell 65 IL 1ß 65 proinflammatory cytokines 65 renal fibrosis 65 myopathies 65 fatty acid oxidation 64 synaptic function 64 constitutively expressed 64 FGFs 64 beta adrenergic receptors 64 cholesterol homeostasis 64 Wnt pathway 64 synapse formation 64 neuronal signaling 64 Wnt signaling 64 methyl D aspartate 64 proximal tubule 64 5 HT2A receptor 64 hypothalamic pituitary 64 NMDA receptors 64 STAT3 64 glutamate signaling 64 beta1 integrin 64 thioredoxin 64 selectively inhibited 64 phosphorylates 64 mitogenic 64 CXCL# 64 γ secretase 64 SCD1 64 apoE4 64 Upregulation 64 hydrolases 64 selective inhibition 64 TORC2 64 Factor Receptor 64 GABAA receptors 64 fatty acid synthase 64 Protein Kinase C 64 circadian genes 64 excitotoxic 64 nitric oxide synthase 64 Factor VEGF 64 ACh 64 TGF β 64 Hedgehog signaling 64 cell adhesion molecule 64 thyrotropin 64 ERK pathway 64 coagulation cascade 64 4E BP1 64 protein tyrosine kinase 64 leptin receptor 64 LPA1 receptor 64 COMT 64 glycolipids 64 mitochondrial enzyme 64 chromatin remodeling 64 MMP2 64 beta endorphin 64 LDLR 64 microglial activation 64 induces apoptosis 64 apoE 64 Hedgehog pathway 64 IGFBP2 64 downregulates 64 fatty acid metabolism 64 FasL 64 Brain derived neurotrophic 64 Hypoxia Inducible Factor 64 GSK 3ß 64 NFAT 64 E#F# 64 upregulation 64 neurotransmitters serotonin 64 CagA 64 MAPK 64 potent inducer 64 microtubule dynamics 64 eotaxin 64 IL6 64 paracrine 64 activin 64 nAChRs 64 Pten 64 nicotinic receptor 63 corticotropin releasing factor 63 epigenetic modification 63 partial agonist 63 amyloid β 63 endocrine glands 63 HIF 1a 63 acyl CoA 63 Wnt signaling pathway 63 excitotoxicity 63 receptor tyrosine kinase 63 CYP #A# 63 gene polymorphisms 63 PPARγ 63 oxidative enzymes 63 tumor suppressor protein 63 activated microglia 63 Dystrophin 63 EZH2 63 PAR1 63 inherited mutations 63 pathophysiological 63 oncogenic 63 tumorigenesis 63 Kv#.# 63 tyrosine kinases 63 allergic inflammation 63 cyclin E 63 MAP kinases 63 proapoptotic 63 LRP6 63 hyperactivated 63 JAK2 63 NMDA N 63 #HT#A 63 mice lacking 63 Activating mutations 63 TNFalpha 63 5 HT1A receptor 63 JAK2 enzyme 63 XBP1 63 SIRT3 63 Hypothalamic 63 antiapoptotic 63 polyamines 63 adhesion molecule 63 NR#A# 63 modulatory 63 PI3K Akt 63 downregulate 63 arginase 63 adipokine 63 CaM kinase II 63 p# MAPK 63 nociceptive 63 TRPV1 receptors 63 neuronal apoptosis 63 inducible nitric oxide synthase 63 tyrosine kinase 63 hypothalamus pituitary 63 epigenetic alterations 63 neurogenic 63 cholinergic 63 DISC1 63 V#F mutation 63 nAChR 63 metabolic enzymes 63 TRAIL induced apoptosis 63 PKC inhibitors 63 mRNA expression 63 NMDAR 63 isoenzyme 63 BMP signaling 63 adrenocortical 63 pDCs 63 pathophysiological effects 63 insulin signaling pathways 63 HGPS 63 Hh pathway 63 arcuate nucleus 63 MEK1 63 VEGF receptor 63 axon guidance 63 synapse maturation 63 GABA receptor 63 BRAF protein 63 neurosteroid 63 neurofibromin 63 CEACAM1 63 p#Kip# 63 evolutionarily conserved 63 S6K 63 mTOR signaling 63 NF kB pathway 63 neuronal plasticity 63 downstream effector 63 TGF β1 63 Akt 63 PI3K/AKT 63 beta catenin 63 MECP2 gene 63 proinflammatory cytokine 63 RUNX3 63 airway remodeling 63 leukocyte adhesion 63 Oxidative stress 63 serotonin transporter 63 IL #p# 63 Inhibitory 63 neuronal nitric oxide synthase 63 SIRT1 gene 63 serine protease 63 endogenous opioid 63 proteolysis 63 STAT1 63 hepatic lipase 63 oncogenesis 63 receptor gamma 63 peroxisomal 63 catecholamine 63 vWF 63 FMRP protein 63 5 HT6 receptor 63 TORC1 63 downregulated 63 mTORC1 63 Oncogenic 63 Prolactin 63 brain hypothalamus 63 FGFR3 63 selective modulator 63 Aß 62 lowers blood glucose 62 hypoxia inducible factor 62 Neurogenesis 62 gamma aminobutyric acid 62 protein tau 62 missense mutations 62 Notch receptor 62 huntingtin protein 62 Rab5 62 antibody mediated 62 TSC1 62 AhR 62 AgRP 62 inhibitory 62 H#K# methylation 62 synaptic plasticity 62 phosphorylate 62 SH2 B 62 LIS1 62 HIF 1alpha 62 glucocorticoid 62 lipid homeostasis 62 SLC#A# [002] 62 ADAM# 62 NKT cell 62 casein kinase 62 excitatory synapses 62 endogenous cannabinoids 62 GABAergic 62 Leydig cell 62 Notch1 62 phosphate S1P 62 fibrogenesis 62 CB1 receptors 62 mitochondrial dysfunction 62 improves insulin sensitivity 62 lymphocyte activation 62 neuropeptide Y 62 intestinal epithelium 62 prostaglandin synthesis 62 WNK1 62 caveolin 1 62 HbF 62 GSTT1 62 excess glutamate 62 melatonin receptors 62 leptin resistance 62 pro angiogenic 62 CCR2 62 ornithine decarboxylase 62 IL 1beta 62 functional polymorphism 62 nicotinic receptors 62 p# mutations 62 Gleevec inhibits 62 CHD5 62 airway hyperresponsiveness 62 mediated inhibition 62 Kupffer cells 62 calcium homeostasis 62 cAMP signaling 62 homodimers 62 Skp2 62 folate metabolism 62 lipid metabolism 62 lipid rafts 62 neurotransmitter GABA 62 D2 receptor 62 anti apoptotic 62 lipoprotein metabolism 62 transcriptional activation 62 motor neuron degeneration 62 inhibitory transmitter 62 pancreatic endocrine 62 cardiolipin 62 ectopic expression 62 NK1R 62 Cyclin E 62 cell adhesion molecules 62 glomerular 62 CB2 receptor 62 E3 ligase 62 cell signaling pathways 62 Thyroid hormone 62 uPAR 62 amyloid peptide 62 signaling cascade 62 demyelination 62 TrkB 62 receptor subtypes 62 receptor activation 62 MMP9 62 NF kappaB activation 62 opioid peptides 62 PTP1B 62 HIF 2alpha 62 DQB1 * 62 PECAM 1 62 SGLT1 62 phospholipase A2 62 FANCD2 62 colorectal carcinogenesis 62 resistin 62 nNOS 62 SGK1 62 alpha glucosidase 62 phosphoinositide 62 SGLT2 62 Glutamate 62 MDM2 62 GRK2 62 cAMP 62 aberrantly activated 62 induced apoptosis 62 HMG CoA reductase 62 CTGF 62 Th1 cells 62 Elevated serum 62 prostaglandin E2 PGE2 62 p# alpha [001] 62 cypin 62 Rap1 62 NFkB 62 cyclooxygenase 2 62 TNFα 62 Th2 62 Hsp# [001] 62 autoimmune thyroiditis 62 serine threonine 62 acetylcholinesterase 62 cellular metabolism 62 acid GABA 62 adipogenic 62 KRAS oncogene 62 COX2 62 PDE#A 62 intracellular signal transduction 62 PDGF receptor 62 microglial cells 62 PI3 kinase 62 urocortin 62 glutamate receptor 62 NF kappaB pathway 62 BDNF 62 orexin receptors 62 metabolizing enzymes 62 Kir#.# 62 p# mitogen activated 62 PPAR γ 62 Purkinje cell 62 CYP#B# 62 S#A# [002] 62 NOTCH1 62 fibrotic disease 62 glucagon receptor 62 mTOR 62 beta catenin protein 62 VE cadherin 62 TCF#L# 62 LDL receptor 62 systemic inflammation 62 sphingolipid 61 Src 61 PKC beta 61 mitochondrial mutations 61 Angiotensin converting enzyme 61 Overexpression 61 PGC 1α 61 antidiuretic hormone 61 triggers apoptosis 61 Glucocorticoids 61 DNMT1 61 leptin receptors 61 signaling molecule 61 myeloproliferative diseases 61 mGluR2 NAM 61 JAK STAT signaling 61 Th2 cells 61 protein tyrosine phosphatases 61 podocytes 61 chemokine receptor 61 TrkA 61 Rho GTPases 61 virulence genes 61 chromosomal rearrangement 61 Htt 61 mutated protein 61 FGFR1 61 chronic eosinophilic leukemia 61 isoenzymes 61 gene locus 61 EGFR signaling 61 pathogenetic 61 inflammatory cytokines 61 insulin receptors 61 serine threonine kinase 61 apoptosis pathways 61 malonyl CoA 61 underlying vasculopathy 61 Fibroblast 61 tumor stroma 61 alpha catenin 61 V2 receptor 61 MT1 MMP 61 neurotransmitter 61 EBV infection 61 myeloid 61 calpain 61 upregulated 61 baroreceptor 61 oncoprotein 61 XL# inhibits 61 methylenetetrahydrofolate reductase 61 HepG2 cells 61 p# mutation 61 Neuronal 61 paxillin 61 genotoxic stress 61 CDKs 61 estrogen receptor alpha 61 calcineurin 61 mTOR pathway 61 Cyclin D1 61 PHD2 61 HSF1 61 GABA receptors 61 astrocytic 61 dystroglycan 61 FLT3 61 AMPA receptors 61 synovial cells 61 histone deacetylation 61 #beta HSD1 61 FOXO3a 61 dephosphorylation 61 IRAK1 61 CHD7 61 metalloprotease 61 related apoptosis inducing 61 Cdc7 61 TSLP 61 M1 macrophages 61 lysyl oxidase 61 Aβ 61 D aspartate 61 costimulatory 61 matrix metalloproteinases 61 intracellular protein 61 microglial 61 downregulating 61 FoxO1 61 Stat5 61 iNOS 61 glutamate neurotransmitter 61 BMPR2 61 eicosanoids 61 hypermethylation 61 tyrosine hydroxylase 61 renal tubular 61 prefrontal cortical 61 PTP 1B 61 HDAC enzymes 61 tumor vasculature 61 peroxynitrite 61 HDACs 61 Abeta protein 61 glucocorticoid receptors 61 Smoothened 61 renin angiotensin system 61 stathmin 61 neuropeptides 61 monoamine 61 aldehyde dehydrogenase 61 leaky gut 61 erythropoiesis 61 Monocyte 61 retinoid X 61 receptor gene 61 DARPP 61 GluR1 61 Oxidative damage 61 SMAD4 61 SIRT1 61 cathepsins 61 cyclic AMP cAMP 61 osteoclast formation 61 hereditary predisposition 61 VIPR2 61 GTPases 61 predisposing factor 61 interferon pathway 61 polyglutamine 61 LPA1 61 catechol O methyltransferase 61 adrenal hormone 61 endothelial activation 61 locus coeruleus 61 enzymatic activity 61 neurite outgrowth 61 interleukins 61 tau phosphorylation 61 cell signaling pathway 61 MTHFR 61 osteoblast 61 transcriptional repressor 61 kappa opioid receptors 61 PPAR gamma 61 hedgehog pathway 61 neuronal cell 61 KCNH2 61 E selectin 61 hydrolase 61 Dopaminergic 61 mediated apoptosis 61 SOD1 protein 61 epigenetic mechanisms 61 growth hormone secretion 61 elevated cortisol 61 Flt3 61 efferent 61 Aldosterone 61 SOCS1 61 Rho GTPase 61 IGFBP 3 61 lymphangiogenesis 61 CaMKII 61 MEK ERK 61 interleukin 1β 61 dopaminergic neurons 61 TGF beta 61 CD#b 61 PP2A 61 misregulation 61 elastase 61 histone methyltransferase 61 Acetylcholine 61 neutrophil recruitment 61 neurofibrillary tangles 61 transmembrane protein 61 mevalonate 61 c myc gene 61 overexpressed 61 striatal dopamine 61 Src kinase 61 PDGFR alpha 61 P#X# receptor 61 superoxide dismutase 61 Six3 61 TGFß 61 Insulin resistance 61 mu opioid 61 cardiac hypertrophy 61 PAK1 61 SIRT6 61 ERBB2 61 kinase pathway 61 dopamine D2 61 UCP1 61 apo AI 61 dentate gyrus 61 chemokine 61 E cadherin expression 61 β1 61 neurosteroids 61 oncomodulin 61 BCR ABL 61 N Myc 61 Smad7 61 PIK3CA 61 5 hydroxytryptamine 61 IKKß 61 FUS1 61 Th1 61 serotonin transporters 61 MDSCs 60 soluble fms 60 hormone secreted 60 vascular endothelial 60 endoplasmic reticulum stress 60 dopamine transporter 60 mitogen 60 mTOR mammalian target 60 striatal neurons 60 β cells 60 peptide hormone 60 lipid peroxides 60 overexpression 60 Endocannabinoids 60 hepatic stellate cells 60 beta subunit 60 PKC isoforms 60 FKBP# 60 Cathepsin B 60 p#INK#a 60 p# Shc 60 CatB 60 axonal damage 60 BCL#A 60 Parkinsonian 60 glycogen metabolism 60 HIF 1α 60 α synuclein 60 Hashimoto thyroiditis 60 cholecystokinin CCK 60 5 HT2A serotonin 60 neuronal synapses 60 neuropeptide Y NPY 60 Orexin 60 DLX5 60 MLH1 60 inflammatory cytokine 60 glucagon secretion 60 pro apoptotic 60 protein p# 60 Androgen 60 vitamin D receptors 60 catabolism 60 Nedd4 60 autoantigen 60 HDAC2 60 constitutively activated 60 cytoskeletal 60 receptor mediated endocytosis 60 gastric carcinogenesis 60 Bcl xL 60 muscarinic 60 metabolizing enzyme 60 neuropsychiatric diseases 60 overexpressing 60 diffusible 60 KLF4 60 stellate cells 60 miR #a [001] 60 immunoregulatory 60 LPS induced 60 basophils 60 GRP# 60 aldosterone 60 CYP# [002] 60 act synergistically 60 opioid receptor 60 nicotinic 60 serotonin signaling 60 TGF ß1 60 neurotrophin 60 vimentin 60 progranulin 60 hypothalamic pituitary adrenal HPA 60 procaspase 3 60 CB1 receptor 60 melanocyte 60 pro inflammatory cytokine 60 ouabain 60 ADAMTS# 60 undergo apoptosis 60 Mice lacking 60 encodes protein 60 CDK inhibitor 60 tyrosine kinase receptor 60 acetyltransferase 60 pathogenic mechanisms 60 aP2 60 inhibitory neurotransmitter 60 H#K#me# 60 IFN γ 60 downstream effectors 60 vascular endothelial cells 60 adrenal hormones 60 excitatory 60 FGFR4 60 FGFR 60 estrogen receptor beta 60 caveolae 60 bile acid 60 Vascular endothelial growth 60 epigenetically 60 tumor suppressor gene 60 HBx 60 exocrine 60 TGF Beta 60 nitric oxide synthase NOS 60 NF kB signaling 60 C5aR 60 cellular pathways 60 corticotropin releasing hormone 60 insulin secretion 60 regulated kinase 60 mPFC 60 oncogenes 60 ERa 60 TLR8 60 cardiac fibrosis 60 experimental autoimmune encephalomyelitis 60 MAP kinase pathway 60 antiproliferative activity 60 peroxisome proliferator activated 60 neurotrophins 60 osteopontin 60 neuroligins 60 PGC1 60 NMDA receptor 60 cdk5 60 oxidases 60 acinar 60 druggable target 60 alpha synuclein gene 60 transcriptional regulation 60 INH naturally occurring 60 utrophin 60 receptor partial agonist 60 FOXO 60 nitrotyrosine 60 TGF beta pathway 60 GLI1 60 vasodilatation 60 TGFβ 60 neurotrophic factors 60 chemokine receptors 60 malignant transformation 60 neurotransmitters dopamine 60 CCL# 60 NFκB 60 clusterin 60 dysgenesis 60 polyamine 60 PDE1 60 inhibitory effects 60 tumor suppressive 60 neuronal cells 60 trastuzumab resistant 60 lymphoid cells 60 super oxide dismutase 60 plasminogen 60 heme oxygenase 1 60 P glycoprotein 60 ErbB4 60 p tau 60 GATA3 60 tryptase 60 telomere maintenance 60 gastric carcinoma 60 ERK5 60 VEGF expression 60 presenilin 60 sporadic ALS 60 TRPV3 60 adenylate cyclase 60 cyclic nucleotide 60 acetylated 60 adenosine receptors 60 tau protein 60 p#NTR 60 enkephalin 60 cortical excitability 60 endothelial nitric oxide synthase 60 epithelia 60 PKD1 60 intracellular signaling 60 GABA gamma aminobutyric acid 60 insulin signaling pathway 60 neuropsychiatric disorders 60 #HT#A receptor 60 metabolize cholesterol 60 incretin 60 Wnt1 60 cellular prion protein 60 Mcl 1 60 glial tumors 60 hypocretin 60 Fas ligand 60 NKX2 60 heme oxygenase 60 Akt pathway 60 neuronal degeneration 60 protein kinases 60 renin angiotensin aldosterone 60 lipoprotein lipase 60 hormone aldosterone 60 Raf MEK ERK 60 cannabinoid receptors 60 p# pathway 60 proNGF 60 Androgen receptor 60 IL#R 60 regulating gene expression 60 cytoprotective 60 transactivation 60 uPA 60 SOD1 60 NF KB 60 hyperalgesia 60 vascular permeability 60 melanocortin 60 PI3K/Akt 60 neurohormone 60 serotonin reuptake 60 adrenoceptor 60 huntingtin 60 brain neurotransmitter 60 FSH receptor 60 dorsolateral 60 hepatic steatosis 60 ABCB1 60 endogenous ligand 60 DNA methylation patterns 60 hyperphosphorylation 60 transmembrane receptor 60 MetAP2 60 metalloproteinases 60 Th1 type 60 neurofibrillary 60 CGRP 60 genes encode proteins 60 oxidative phosphorylation 60 RBP4 60 estrogen metabolism 60 TNF α 60 histone acetylation 60 mitogen activated protein kinases 60 cytokine receptor 60 ligand TRAIL 60 TNFa 60 immunomodulatory effects 60 acetylcholine receptors 60 5 lipoxygenase 60 SMN1 60 C1q 60 sulfatase 60 pathophysiologic 60 Aurora kinase 60 hepatic glucose production 60 Immunohistochemical analysis 60 epithelial tissues 60 SIRT2 60 Chronic pancreatitis 60 Genetic predisposition 60 neuregulin 60 autoregulation 60 myocyte 60 polyglutamine diseases 60 Nampt 60 neurotransmitter dopamine 60 leukemic stem cells