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(Click for frequent words.) 63 signal transduction pathways 62 kinases 62 protein kinase 62 protein kinases 61 GPCRs 61 tyrosine kinases 60 VIPR2 60 Kinases 59 histone deacetylases 59 transmembrane proteins 59 tumor suppressors 58 hypoxia inducible factor 58 signal transduction 58 rapamycin mTOR 58 tyrosine kinase 58 Aurora kinases 58 histone deacetylase 58 receptors PPARs 58 serine threonine kinase 58 sphingosine 1 58 serine protease 57 transient receptor 57 intracellular signaling pathways 57 transmembrane protein 57 protein tyrosine phosphatases 57 glutamate receptors 57 NMDA N 57 phosphoinositide 3 57 AT1R 57 HDAC 57 tRNA synthetase 57 serine threonine 57 potent inhibitors 57 cyclin dependent kinases 57 cathepsins 57 HDAC enzymes 57 deacetylase 57 proteases 57 ErbB3 57 chemokine 57 small molecule inhibitor 57 TLR8 56 PI3 kinase 56 intracellular protein 56 binding proteins 56 kinase 56 VEGF receptor 56 IGF 1R 56 methyl D aspartate 56 glutamate receptor 56 ErbB3 HER3 56 ubiquitin ligases 56 intracellular signaling 56 HDACs 56 mTOR 56 ribonuclease 56 adhesion molecule 56 CCR3 56 phosphate S1P 56 major histocompatibility complex 56 GPCR 56 ion channels 56 tyrosine kinase receptor 56 PI3K pathway 56 FLT3 56 chaperone protein 55 casein kinase 55 immunoregulatory 55 microRNAs miRNAs 55 CD# receptor 55 selective inhibitor 55 MAPK 55 peroxisome proliferator activated 55 anaphase promoting complex 55 SIRT1 gene 55 non coding RNA 55 chemokine receptor 55 signaling molecule 55 phosphatases 55 tumor suppressor protein 55 miR #b [002] 55 retinoic acid receptor 55 NS4B 55 kinase PI3K 55 secreted protein 55 neuropeptide 55 Protein Kinase C 55 activin 55 receptor molecule 55 regulates gene expression 55 JAK3 55 ErbB 55 selective inhibitors 55 receptor tyrosine kinase 55 sphingolipid 55 evolutionarily conserved 55 cyclin dependent kinase inhibitor 55 NF κB 55 beta arrestin 55 metabolic enzymes 55 mitogen activated protein kinase 55 5 HT2A receptor 55 selectively inhibit 55 Flt3 55 ENaC 55 5 HT4 receptor 55 small molecule inhibitors 55 serine proteases 55 synthetase 55 receptor 55 Janus kinase 54 HCV protease 54 estrogen receptor beta 54 histone deacetylase inhibitors 54 Abl 54 membrane receptors 54 signaling cascades 54 glycosyltransferase 54 Wnt signaling pathway 54 receptors 54 FGFR 54 cellular pathways 54 CCR2 54 hnRNP 54 enkephalin 54 acetylcholine receptor 54 cell signaling pathways 54 catenin 54 receptor alpha 54 encodes protein 54 glucocorticoid receptors 54 hedgehog pathway 54 EGFR pathway 54 transcription factors 54 Kinase 54 phosphatidylinositol 3 54 MEK ERK 54 G Protein Coupled 54 PPAR alpha 54 signaling pathways 54 signaling pathway 54 COX2 54 PKM2 54 cyclins 54 Wnt beta catenin 54 receptors EGFR 54 fusion proteins 54 Orexin 54 TNFR 54 serine threonine kinases 54 Skp2 54 androgen receptor AR 54 adenosine receptor 54 PPAR gamma 54 PPARg 54 lipoxygenase 54 ion channel 53 protein kinase C 53 5 lipoxygenase 53 NS5A 53 c MET 53 inverse agonist 53 GSK3B 53 inhibitory receptor 53 bacterial enzyme 53 ADAM# 53 potent inhibitor 53 LRP6 53 NF kappa B 53 TNFalpha 53 CB2 receptor 53 Aurora kinase 53 glucocorticoid receptor 53 E#F# 53 cell adhesion molecules 53 potently inhibit 53 proto oncogene 53 cytochrome P# 53 telomerase reverse transcriptase 53 uPAR 53 TNF receptors 53 ERK1 2 53 eotaxin 53 Notch receptor 53 cell adhesion molecule 53 thyroid hormone receptor 53 PTP 1B 53 beta amyloid peptide 53 NF kB pathway 53 cyclin dependent kinase 53 miR #a [002] 53 serotonin receptor 53 calcineurin 53 MUC1 53 oncogenic 53 NFkB 53 MAPK pathway 53 CDKs 53 receptor kinase 53 p# MAPK 53 P#X# receptor 53 Hsp# inhibitors 53 GTPases 53 deacetylases 53 cell signaling pathway 53 Cytotoxic T 53 PI3K 53 cannabinoid receptors 53 coactivator 53 kinase enzymes 53 Akt1 53 tumor antigen 53 PPARgamma 53 apoptotic pathway 53 tumor suppressor gene 53 signaling molecules 53 p# mitogen activated 53 thrombospondin 53 oncogenesis 53 nNOS 53 FGFs 53 receptor protein 52 catalytic subunit 52 noncoding RNA 52 aberrantly activated 52 NKG2D 52 ligases 52 JAK2 52 neuromuscular junction 52 poly ADP ribose polymerase 52 Hedgehog pathway 52 PI3 K 52 glycoprotein 52 LDL receptor 52 Upregulation 52 microRNA molecules 52 glycolipids 52 NF kappaB pathway 52 NKT cells 52 MAP kinase 52 adenylyl cyclase 52 GPR# [002] 52 peptide 52 CD# ligand 52 receptor antagonists 52 cyclooxygenase 2 52 Smad3 52 Syk 52 proteoglycan 52 GPR# [001] 52 glucagon receptor 52 receptor agonist 52 HCV replication 52 calpain 52 intracellular pathways 52 beta adrenergic receptors 52 superfamily 52 HMG CoA reductase 52 EphA2 52 STAT3 52 FoxO1 52 PDGFR 52 E3 ligase 52 GABA receptors 52 PKC alpha 52 chemokine receptors 52 downregulation 52 PI3K Akt 52 thrombin receptor 52 Factor Receptor 52 bispecific 52 molecular pathway 52 prolyl 52 tumor suppressor genes 52 effector functions 52 ubiquitin ligase 52 Rho GTPase 52 vanilloid receptor 52 regulated kinase ERK 52 FGFR1 52 Stat3 52 FOXO3a 52 micro RNA 52 Hedgehog signaling pathway 51 receptor agonists 51 kinase inhibitors 51 MEK1 51 KLF4 51 downstream effector 51 innate immunity 51 EGFR protein 51 cytoplasmic domain 51 sortilin 51 NF kappaB 51 RNA splicing 51 EGF receptor 51 IGF1R 51 protein phosphatase 51 E2F 51 agonist compounds 51 Kv#.# 51 NFAT 51 FGFR2 51 SIRT2 51 costimulatory 51 STIM1 51 Tumor necrosis factor 51 CDK9 51 protein phosphorylation 51 USP# 51 cyclooxygenase 51 Arp2 3 51 biosynthesis 51 NF kB 51 HDAC inhibitors 51 molecular pathways 51 allosteric 51 CRAC channel 51 JAK2 enzyme 51 cAMP signaling 51 DNA methyltransferases 51 NFκB 51 biological pathways 51 interleukins 51 nicotinic receptor 51 phosphatidylinositol 51 TRPV1 51 oxidase 51 Mcl 1 51 T#R# 51 kinase substrate 51 synaptogenesis 51 γ secretase 51 nicotinic receptors 51 RANKL 51 kinase domain 51 messenger molecule 51 P#X# 51 S1P 51 endogenous ligands 51 Huntingtin 51 IL 1β 51 HER1 51 antiapoptotic 51 CXCR2 51 TLRs 51 splice variant 51 PKC isoforms 51 Wnt pathway 51 kinase pathway 51 protein fragment 51 SIRT1 51 FOXO 51 metabotropic glutamate receptors 51 mediated apoptosis 51 metalloprotease 51 PPARγ 51 membrane protein 51 mitotic kinesin 51 receptor PPAR 51 CK2 51 PLK1 51 CXCR4 51 apoptosis pathways 51 FKBP# 51 splice variants 51 EP3 receptor 51 fusion protein 51 micro RNAs 51 cyclin dependent kinases CDKs 50 receptor subtype 50 TGF b 50 VE cadherin 50 CDK5 50 pRb 50 peptide hormone 50 extracellular domain 50 beta catenin 50 PKD1 50 nAChRs 50 PDGF receptor 50 somatostatin 50 dimerization 50 Protein Kinase 50 sensory neurons 50 FGFR3 50 transcriptional activation 50 transcriptional repressor 50 inhibitory 50 Cdc7 50 GGTase 50 CTLA 4 50 membrane proteins 50 Rab# 50 proteins encoded 50 CENP E 50 LSD1 50 proteins 50 T lymphocytes 50 superoxide dismutase 50 peptides 50 PAK1 50 mTOR pathway 50 phosphoinositide 50 noncoding RNAs 50 secreted proteins 50 p#/CBP 50 5 HT1A 50 arginase 50 #HT#A 50 c MYC 50 Notch receptors 50 MAPKs 50 tumor microenvironment 50 epigenetic 50 cytochrome P 50 c myc 50 kinase inhibition 50 reductase 50 Sox2 50 siRNA mediated 50 selective inhibition 50 cannabinoid receptor 50 cellular organelles 50 E3 ubiquitin ligase 50 miRNAs 50 HER2 receptor 50 tumor angiogenesis 50 NMDA receptor 50 regulating gene expression 50 C1q 50 synaptic transmission 50 TLR9 50 TGF alpha 50 constitutively activated 50 LXRs 50 mu opioid receptors 50 kinase inhibitor 50 genes encoding 50 Notch signaling 50 EGFr 50 DARPP 50 IKK2 50 glucokinase 50 chromatin remodeling 50 apoE 50 tumor suppressor 50 receptor gamma 50 B Raf 50 receptor gene 50 virulence genes 50 opioid receptors 50 partial agonist 50 transcription factor 50 endocannabinoid system 50 phosphorylates 50 polypeptide 50 protein 50 iNOS 50 c Myc 50 dephosphorylation 50 lysosomal 50 TRPV3 50 costimulation 50 induce apoptosis 50 GTPase 50 BCR ABL 50 Rap1 50 antisense oligonucleotide 50 c KIT 50 glial cell 50 K + ATPase 50 protein interleukin 50 muscarinic 50 glycogen synthase kinase 50 oligomerization 50 PIK3CA 50 methyltransferase 50 incretin 50 Survivin 50 LPA1 50 secretory pathway 50 UCP2 50 nicotinic acetylcholine receptor 50 membrane glycoprotein 50 integrin receptors 50 CaM kinase II 50 pro angiogenic 50 oncoprotein 50 PPAR γ 50 methyltransferases 50 mTOR signaling 49 transcriptional regulation 49 rRNA 49 LRRK2 49 β catenin 49 dopamine receptors 49 forkhead 49 microRNAs 49 Src 49 IGFBP2 49 ENMD # 49 potent inhibition 49 cofactor 49 GRP# 49 CD#b 49 isoenzymes 49 POMC neurons 49 triphosphate 49 adhesion molecules 49 opiate receptors 49 TRAF6 49 Ras pathway 49 JAK STAT 49 small molecule 49 tumor vasculature 49 transmembrane receptor 49 NFkappaB 49 decarboxylase 49 PCSK9 49 transduce 49 TrkA 49 FasL 49 amino acid residues 49 nicotinic 49 Interferon gamma 49 CaMKII 49 IL #R 49 homodimers 49 homolog 49 lectins 49 c Abl 49 sirtuin 49 SMAD4 49 CRF1 receptor 49 tropomyosin 49 NR2B subunit 49 PI 3K 49 matrix metalloproteinases 49 Notch1 49 cadherin 49 Clusterin 49 mGluRs 49 receptor tyrosine kinases 49 CIB1 49 syntaxin 49 downstream effectors 49 gamma secretase 49 paxillin 49 pDCs 49 NMDA receptors 49 biochemical pathway 49 Nedd4 49 TMEM#B 49 RANK ligand 49 CD1d 49 DLX5 49 transactivation 49 H#K# [002] 49 NF KappaB 49 SWI SNF 49 cyclic AMP cAMP 49 Hedgehog signaling 49 HDAC6 49 glycoproteins 49 MMP9 49 HER3 49 BCL6 49 Vps# 49 Cdc# 49 antisense oligonucleotides 49 biochemical pathways 49 cell motility 49 antisense 49 estrogen receptors 49 fascin 49 cyclin D1 49 caveolin 49 4E BP1 49 Akt signaling 49 VEGFR2 49 CB1 receptors 49 GRK2 49 cholecystokinin CCK 49 anti apoptotic 49 IL 1beta 49 Galectin 49 hyperactivation 49 polypeptides 49 GATA3 49 Vascular endothelial growth 49 extracellular signal 49 adaptive immune 49 Fibroblast Growth Factor Receptor 49 Cyclin E 49 receptor subtypes 49 histone modifications 49 5 HT2A 49 Hh 49 MDSCs 48 ERK pathway 48 p# gene 48 Methylation 48 Rho kinase 48 N Myc 48 macrophage activation 48 hTERT 48 isoforms 48 melatonin receptors 48 PTPN# 48 epigenetically 48 glycosylation 48 ligands 48 S#P# 48 Abeta peptide 48 glycosylated 48 Akt activation 48 colony stimulating factor 48 CD# [002] 48 oncogenic proteins 48 tetherin 48 cellular metabolism 48 inhibitor 48 neurotransmitter receptors 48 DISC1 48 TNFα 48 related apoptosis inducing 48 AMPA receptor 48 selenoproteins 48 podocytes 48 topoisomerases 48 dopaminergic 48 MMP2 48 muscarinic receptors 48 inducible 48 cystic fibrosis transmembrane conductance 48 HDAC2 48 PTP1B 48 proapoptotic 48 microglial activation 48 IRAK1 48 ligase 48 vimentin 48 estrogen receptor alpha 48 RNAi pathway 48 ncRNAs 48 TGF β 48 Bcr Abl 48 HSP# 48 epitopes 48 gene expression 48 adenosine receptors 48 miRNA 48 isotypes 48 tumorigenesis 48 ras gene 48 TLR7 48 synapse formation 48 receptor molecules 48 TRPV1 receptors 48 SGLT2 48 retinoblastoma protein 48 vitamin D receptors 48 pleiotropic 48 DGAT1 48 TLR4 48 Apoptosis 48 chromatin structure 48 upregulated 48 Nav#.# 48 receptor signaling 48 ESCRT 48 Wnt1 48 uPA 48 XBP1 48 phosphorylate 48 demethylase 48 IRE1 48 PAR1 48 ABCA1 48 AMPA receptors 48 Akt 48 Fc receptor 48 VEGFR 48 acetylcholinesterase 48 isoform 48 RAR beta 48 Th# 48 mTOR inhibitors 48 neurite outgrowth 48 chitinase 48 NKX#.# 48 p# tumor suppressor 48 Notch pathway 48 FGF# 48 DNA gyrase 48 primary cilia 48 phosphorylated 48 nitric oxide synthase 48 STAT1 48 IKKa 48 factor receptor 48 H#K# methylation 48 Rb#/p# 48 autoantibody 48 pro apoptotic 48 galectin 48 tyrosine phosphorylation 48 HDAC inhibitor 48 acetylation 48 Receptors 48 WASp 48 gene encoding 48 alternatively spliced 48 protease 48 TGFβ 48 oxidative phosphorylation 48 coreceptor 48 lymphotoxin 47 oncogene 47 Eg5 47 membrane fusion 47 TRP channels 47 Smurf1 47 serotonin receptors 47 non coding RNAs 47 EGFR 47 Wnt#b 47 TORC1 47 gene transcription 47 miR #a [001] 47 MAP kinase pathway 47 IKKß 47 SGK1 47 inhibitory receptors 47 ubiquitylation 47 ERK signaling 47 Pten 47 neurofibromin 47 cytokines IL 47 mRNA molecules 47 downregulated 47 P#X# receptors 47 RUNX3 47 eNOS 47 viral proteins 47 STK# [002] 47 EZH2 47 Lyn kinase 47 nAChR 47 MAP kinases 47 D aspartic acid 47 CXCL# 47 substrate specificity 47 IFN γ 47 cytokine receptors 47 epigenetic alterations 47 thioredoxin 47 oncogenes 47 cytosolic 47 caveolin 1 47 lipid synthesis 47 protein CETP 47 deacetylation 47 proteolysis 47 osteoclast activity 47 Wnts 47 survivin 47 TRPA1 47 SH2 B 47 secretase 47 kappa opioid receptor 47 IL 1ß 47 PKCi 47 autocrine 47 synapse maturation 47 neurotransmitter glutamate 47 upregulation 47 ErbB4 47 LIS1 47 beta2 adrenergic receptor 47 cannabinoid 47 chemokines 47 cyclic nucleotide 47 innate immune response 47 podocyte 47 vWF 47 PC# cells 47 GluR1 47 Overexpression 47 interneurons 47 cyclin E 47 defensin 47 CpG 47 tubulin 47 subunit 47 SREBP 47 vascular endothelial growth 47 proteolytic cleavage 47 ryanodine receptor 47 cyclic guanosine monophosphate cGMP 47 SOD1 47 sensing neurons 47 osteoblast 47 TNF α 47 heterodimer 47 EGF receptors 47 plasminogen 47 neurodegeneration 47 Hsp# [002] 47 endothelial nitric oxide synthase 47 Histone 47 TrkB 47 Cyclin D1 47 acetylcholine receptors 47 adrenergic receptors 47 HDAC inhibition 47 NR2B 47 Htt 47 histone acetylation 47 XIAP 47 heterodimers 47 Nampt 47 messenger RNAs 47 cyclin 47 SIRT3 47 druggable target 47 Ago2 47 cyclic AMP 47 intracellular 47 S#K# 47 Dysregulation 47 ChR2 47 CCL# 47 hydroxylase 47 anti angiogenic 47 monocyte 47 Id1 46 HER2 receptors 46 CDK4 46 Caspase 46 glutamatergic 46 caspases 46 DNMT1 46 cytokine 46 phosphorylation 46 fibroblast growth 46 inhibit viral replication 46 endonuclease 46 adaptive immunity 46 topoisomerase 46 invadopodia 46 ERK2 46 Cdk5 46 signaling cascade 46 leptin receptor 46 enzyme 46 effector protein 46 ERa 46 huntingtin 46 TSLP 46 semaphorin 46 inhibitors 46 orexin receptors 46 CD#L 46 exocytosis 46 TLR3 46 receptor subunit 46 enzymatic activity 46 proteinase 46 chaperone proteins 46 receptor mediated 46 Aß 46 estrogen receptor 46 porphyrins 46 lipid rafts 46 RNA molecules 46 ectopic expression 46 transmembrane domains 46 aldose reductase 46 glia 46 thymidylate synthase TS 46 phosphatase 46 HOTAIR 46 elastase 46 tyrosine 46 bile acid 46 beta subunit 46 mesothelin 46 PIP3 46 TRPV1 receptor 46 messenger RNAs mRNAs 46 RhoA 46 biomarker 46 neurotransmitter 46 phospholipid 46 Plk1 46 PHD2 46 nicotinic acetylcholine receptors 46 antibody 46 intron 46 microglial cells 46 eIF4E 46 neuronal plasticity 46 Receptor 46 histone H3 46 Bcl 2 46 MMPs 46 ERK1 46 dsRNA 46 inflammatory cytokines 46 transmembrane 46 shRNAs 46 aT cell 46 MEF2 46 odorant receptor 46 opioid receptor 46 HIF 1alpha 46 CTLs 46 Wnt proteins 46 neuropeptides 46 VEGF 46 Th1 46 morphogen 46 microglial 46 Smoothened 46 homologs 46 prostaglandin E2 PGE2 46 phosphoprotein 46 CB1 receptor 46 single nucleotide polymorphism 46 FOXO1 46 matrix metalloproteinase 46 LED# 46 dopamine transporter 46 clusterin 46 regulated kinase 46 SCD1 46 nucleolin 46 protein encoded 46 chloride channels 46 TGF beta 46 oncoproteins 46 endocannabinoids 46 C. elegans 46 tumor suppressor proteins 46 tyrosine kinase receptors 46 RNA polymerase II 46 TGF ß 46 Th# cells 46 ERBB2 46 androgen receptors 46 LKB1 46 overactivation 46 ligand binding 46 Foxp3 46 immunoglobulin genes 46 ubiquitinated 46 Beta catenin 46 intracellular compartments 45 enzymes 45 cytochrome 45 mu opioid receptor 45 Phosphorylation 45 homodimer 45 induces apoptosis 45 ADDLs 45 integrins 45 RNA polymerase 45 TNFa 45 HLA genes 45 C EBP alpha 45 CYP#E# 45 CB2 receptors 45 gene silencing 45 neuronal differentiation 45 cysteine 45 PGE2 45 transferrin receptor 45 odorant receptors 45 biochemical mechanisms 45 Androgen receptor 45 FGF ligands 45 protein p# 45 calmodulin 45 PPAR 45 endoplasmic reticulum 45 overexpressed 45 GABAA receptors 45 MicroRNA 45 RecA 45 TNF alpha 45 GABA receptor 45 metabolic pathway 45 repressor 45 MDM2 45 pharmacologically 45 neuropeptide Y NPY 45 orexin