Related by context. All words. (Click for frequent words.) 65 compulsive behaviors 64 addictive behaviors 63 compulsive eating 62 pathological gambling 60 binge eating 59 impulsive behaviors 59 binge eating disorders 58 compulsive 58 compulsive disorder 58 obsessive compulsive behaviors 58 compulsive gamblers 58 Obsessive compulsive disorder 57 compulsive tendencies 57 compulsive overeating 57 Compulsive gambling 57 compulsive gambling 57 Trichotillomania 57 destructive behaviors 57 obsessive compulsive disorder 56 hypersexuality 55 addiction 54 compulsivity 54 trichotillomania 54 Pathological gambling 54 addictions 54 alcoholics 54 overeating 53 obsessive compulsive disorders 53 compulsive disorders 53 antisocial tendencies 53 pathological gamblers 52 obsessive compulsive disorder OCD 52 workaholism 52 ritualistic behaviors 52 alcoholism 52 gambling addiction 52 anorexia bulimia 52 Obsessive Compulsive Disorder 51 Pathological gamblers 51 depression anxiety 51 hypochondriasis 51 Compulsive gamblers 51 depression 51 mood disorders 51 dopamine agonists 51 Obsessive Compulsive Disorder OCD 51 OCD 51 Compulsive 50 Binge eating 50 chronic relapsing 50 manic depressive disorder 50 compulsive overeaters 50 schizophrenic bipolar 50 mental illness 50 neuropsychiatric disorder 50 eating binges 50 repetitive behaviors 50 impulsive behavior 50 Sexual arousal 50 bulimia nervosa 50 addictions compulsions 50 anticipatory anxiety 50 nicotine cravings 50 CELEBRATE RECOVERY Bible 50 extreme mood swings 50 Essential tremor 50 behaviors 50 delusions hallucinations 50 compulsive overeaters anorexics 49 morbid jealousy 49 Disordered eating 49 eating disordered 49 compulsive hoarding 49 Anxiety disorders 49 coprolalia 49 body dysmorphic 49 Overindulgence 49 bulimics 49 Gambler Anonymous 49 Yo yo dieting 49 codependency 49 bipolar illness 49 Nar Anon 49 compulsive eaters 49 impulsivity 49 depressive moods 49 degenerative neurological diseases 49 cognitive behavioral 49 paraphilias 49 Attention Deficit Disorder ADD 49 biological predisposition 48 obesity anorexia bulimia 48 tic disorder 48 hormone imbalances 48 Bulimics 48 cravings 48 nocturnal enuresis 48 deviant behaviors 48 hyperactivity inattention 48 Compulsive shopping 48 Bedwetting 48 Perfectionism 48 Schizophrenics 48 Binge Eating Disorder 48 Cognitive therapy 48 manic episode 48 Gam Anon 48 oppositional defiance 48 insomnia 48 acamprosate 48 drug addiction 48 anxiety disorder 48 Mirapex 48 postpartum mood 48 psychiatric disorder 48 bipolar disorder 48 Nicotine addiction 48 Bulimia 48 overeaters 48 paranoia hallucinations 48 hyperarousal 48 stereotypy 48 jealousy possessiveness 48 attention-deficit/hyperactivity 48 painful muscle spasms 48 caregiver burnout 47 Bulimia nervosa 47 maladaptive behavior 47 daytime drowsiness 47 paraphilia 47 Cognitive behavioral therapy 47 sociopathic behavior 47 bipolar disorders 47 Hyperactivity 47 bi polar disorder 47 compulsive gambler 47 Male pattern baldness 47 Irritability 47 Cognitive Behavioral Therapy 47 ADHD Attention Deficit 47 hypochondria 47 nicotine addiction 47 OCD obsessive compulsive disorder 47 Oppositional Defiant Disorder 47 mental disorders 47 neurobiological disorder 47 deviant sexual 47 involuntary tics 47 anorexia nervosa bulimia 47 borderline personality disorder 47 Urge incontinence 47 Borderline Personality Disorder 47 Chronic fatigue 47 sexual compulsivity 47 suicidal impulses 47 addictive substances 47 premenstrual syndrome PMS 47 untreated ADHD 47 obsessional 47 overeater 47 anxiety disorders 47 Compulsive hoarding 47 Peripheral neuropathy 47 Phobias 47 neurological degeneration 47 Social Phobia 47 unhealthy behaviors 47 orthorexia 47 tourette syndrome 47 Kleptomania 47 obsessive compulsive tendencies 47 bulimia anorexia 46 depressive illnesses 46 EATING DISORDERS Food Addicts 46 nicotine dependence 46 compulsive shoppers 46 scrupulosity 46 disordered eating 46 sugar cravings 46 Orthorexia 46 Alcoholics 46 psychostimulant drugs 46 Chronic constipation 46 binge eaters 46 obsessive compulsive 46 body dysmorphic disorder 46 muscle dysmorphia 46 neurobiological mechanisms 46 carbohydrate craving 46 manic depression bipolar disorder 46 Hyperactivity Disorder 46 Overactive bladder 46 impulsiveness 46 antisocial traits 46 schizophrenia manic depression 46 unhealthy snacking 46 disease NAFLD 46 maladaptive behaviors 46 Compulsive hoarders 46 Premature ejaculation 46 comorbid disorders 46 Agoraphobia 46 compulsive obsessive 46 histrionic personality 46 undesirable behaviors 46 depressive relapse 46 neurochemistry 46 psychopathic tendencies 46 maladaptive 46 compulsiveness 46 gambling addictions 45 Fecal incontinence 45 enuresis 45 chronic heartburn 45 Bruxism 45 deviant behavior 45 Body Dysmorphic Disorder BDD 45 disinhibition 45 phobias 45 hyper arousal 45 hopelessness helplessness 45 compulsive masturbation 45 dysphoria 45 psychosomatic illnesses 45 ADHD 45 Chronic cough 45 disinhibited 45 disorder 45 Sexual Addiction 45 paranoia delusions 45 manic depressive illness 45 catastrophizing 45 Restless legs 45 ADD ADHD 45 RECOVERY ANONYMOUS 45 Social Anxiety Disorder 45 irritability nervousness 45 relapse prevention 45 reticular formation 45 personality traits 45 Attention Deficit Hyperactive Disorder 45 inattention hyperactivity 45 Tourette syndrome 45 neurodevelopmental disorder 45 Separation anxiety 45 Tourette Syndrome 45 nicotine craving 45 schizoid personality disorder 45 depression suicidal ideation 45 factitious disorder 45 dopamine agonist therapy 45 overactive bladder symptoms 45 physiological reactions 45 habituation 45 ADHD symptoms 45 neurosis 45 Relaxation techniques 45 Obsessive compulsive disorder OCD 45 pathological gambler 45 neural pathway 45 bulimia 45 undereating 45 carbohydrate cravings 45 cognitive behavioral therapy 45 anxiety insomnia 45 vivid hallucinations 45 attentional bias 44 externalizing disorders 44 ventral prefrontal cortex 44 Zopiclone 44 kleptomania 44 Body dysmorphic disorder 44 Interpersonal psychotherapy 44 chocolate cravings 44 neurobiological 44 Chronic insomnia 44 pathologizing 44 Meth addicts 44 priapism 44 Conduct Disorder 44 schizophrenia bipolar 44 PROMETA Treatment Program 44 assortative mating 44 biochemical imbalance 44 parasomnia 44 male pattern baldness 44 neurochemical 44 overstimulation 44 pharmacological treatments 44 pathological gambling disorder 44 dopaminergic therapy 44 self injurers 44 ego dystonic 44 obsessions compulsions 44 Debtors Anonymous 44 Migraine headache 44 Mindfulness meditation 44 mu opioid agonists 44 Alzheimer Dementia 44 chronic pain 44 NAR ANON 44 Emotional Freedom 44 Spinal cord injury 44 Practicing yoga 44 bruxism 44 Hyperthyroidism 44 repetition compulsion 44 pathological 44 bulemia 44 cortisol secretion 44 dopamine agonist 44 contagious yawning 44 Antisocial Personality Disorder 44 stimming 44 neurobehavioral disorder 44 bedwetting 44 reflux symptoms 44 neediness 44 frontal lobe dysfunction 44 depression schizophrenia bipolar 44 eating disorders 44 prosocial behavior 44 antisocial behaviors 44 Asperger disorder 44 depressives 44 Mood disorders 44 Workaholism 44 perfectionist tendencies 44 anorexia bulimia binge 44 temporomandibular joint disorder 44 Mental Disorders IV 44 Withdrawal symptoms 44 anxiety sleeplessness 44 Impostor Syndrome 44 psychosomatic symptoms 44 countertransference 44 drug induced psychosis 44 undiagnosed bipolar disorder 44 SAD Seasonal Affective Disorder 44 flashbacks nightmares 44 overeating bulimia 44 addictive disorders 44 Binge Eating 44 socially deviant 44 obsessive compulsion 44 Maushart admits 44 Sleep disturbances 44 Bipolar disorder 44 mental illnesses 44 habitual drunkenness 44 clinginess 44 adrenal fatigue 44 Wernicke Korsakoff syndrome 44 Personality disorders 44 Binging 44 psychopathic traits 44 Carpal tunnel 44 maladjustment 44 polydrug 43 Sleeplessness 43 hyperactive impulsive 43 neural substrates 43 Asperger Disorder 43 Migraine headaches 43 addictive tendencies 43 addictive 43 Postnatal depression 43 parasomnias 43 schizotypal 43 childhood traumas 43 neglectful parenting 43 behavioral disinhibition 43 hormonal surges 43 Untreated depression 43 somatic symptoms 43 Obsessive compulsive 43 CYP#E# gene 43 Ciguatera poisoning 43 dyscalculia 43 Gamblers Anonymous meetings 43 Bulimia Nervosa 43 pathological narcissism 43 eating disorders anorexia nervosa 43 Acamprosate 43 dopamine pathways 43 substance abuse 43 neurobiological underpinnings 43 Psoriatic arthritis 43 Body Dysmorphic Disorder 43 temporal arteritis 43 PMS symptoms 43 manic episodes 43 mindfulness 43 psychosomatic illness 43 acrophobia 43 Tourette's 43 chronic migraine headaches 43 Addiction 43 hypothalamic pituitary adrenal axis 43 psychiatric illnesses 43 Habituation 43 dopamine receptor gene 43 migraine aura 43 Binge eaters 43 Posttraumatic stress disorder PTSD 43 se xual 43 brain circuitry 43 nocebo 43 headaches mood swings 43 metabolic readjustment 43 hypoglycemic coma 43 Restless Legs Syndrome 43 Vaginal dryness 43 psychotic episodes 43 Gamblers Anonymous 43 involuntary movements 43 Generalized anxiety disorder 43 depressive illness 43 debilitating affliction 43 Personality Disorder 43 metabolic disturbances 43 hypervigilance 43 obsessive 43 sexually compulsive 43 migranes 43 Sensory Integration Disorder 43 Bipolar Disorder 43 serotonin imbalance 43 neuropsychiatric diseases 43 vertigo dizziness 43 AUDs 43 body dysmorphia 43 Excessive sweating 43 cognitive distortions 43 Myotonic dystrophy 43 intractable hiccups 43 affect lability 43 psychosocial variables 43 Restless Leg Syndrome 43 depressive tendencies 43 PCOD 43 Chronic sleep deprivation 43 distractibility 43 psychopathy 43 overeating anorexia 43 Bed wetting 43 emotional reactivity 43 temper outbursts 43 psychotic disorders 43 sexual dysfunctions 43 sleeplessness 43 inherit predisposition 43 chronic sleep deprivation 43 addict 43 convulsive seizures 43 loneliness boredom 43 urine leakage 43 psychiatric disorders 43 inherited neurological disorder 43 Electroconvulsive therapy 43 sedatives hypnotics 43 suicidal thoughts 43 hypoactive 43 Overeaters Anonymous 43 opioid dependent 43 repressed desires 43 bibliotherapy 43 persistent sexual arousal 43 recovering alcoholics 43 cholinergic tone 43 generalized anxiety 43 Food Addicts 43 Tourette 43 Narcissism 43 intensely pleasurable 43 menstrual migraines 43 Korsakoff syndrome 43 reflux disease 43 tonic clonic seizures 43 inherited retinal degeneration 43 inattentional blindness 43 lowers inhibitions 43 sleep disorders 43 behavioral disturbances 43 Suicidal thoughts 43 Pathological Gambling 43 Reformers Unanimous Christ 43 snoring sleep apnea 43 symptomatology 43 neurobiological basis 43 Adult Attention Deficit 43 unfaithfulness 43 anorexia 43 disc degeneration 43 Co Dependents Anonymous CoDA 43 Chronic Fatigue Syndrome 42 epilepsy 42 psychosis 42 relational aggression 42 irritability 42 Attention Deficit Disorder 42 C1 INH deficiency 42 Irritable bowel syndrome 42 hormonal imbalances 42 anxiety irritability 42 anorexia nervosa 42 Antidepressant medications 42 leptin resistance 42 genetic predisposition 42 schizoid personality 42 gambling addicts 42 Nicotine dependence 42 pleasurable sensations 42 Hashimoto thyroiditis 42 Alateen 42 food intolerances 42 disorders 42 schizo affective disorder 42 akinetic mutism 42 Raynaud syndrome 42 psychotic illnesses 42 addicts 42 premature ejaculation 42 underactive thyroid gland 42 degenerative neurological disease 42 Sexsomnia 42 sexually deviant 42 anorexia sufferers 42 psychotic illness 42 sociopathy 42 potent hallucinogen 42 fibromyalgia 42 possessive jealous 42 sexual deviance 42 affliction 42 Love Addicts Anonymous 42 fearfulness 42 hypomanic 42 persecutory delusions 42 ADD Attention Deficit 42 GABRA2 gene 42 Al-Anon/Alateen 42 Naltrexone 42 agoraphobia 42 homosexual inclinations 42 pro ana sites 42 manic depression 42 risky behaviors 42 baclofen 42 sexless marriage 42 loneliness 42 schizophrenia bipolar disorders 42 mental derangement 42 dyskinesias 42 asperger syndrome 42 inhalant abuse 42 forgetfulness 42 carb cravings 42 Anti depressant 42 mood altering 42 depersonalization disorder 42 schizophrenics 42 Lafora disease 42 psychomotor retardation 42 Cognitive Behavioural Therapy CBT 42 Hypochondria 42 sexless marriages 42 retrograde amnesia 42 Male Menopause 42 Personality Disorders 42 salvinorin 42 Anorexia bulimia 42 recurrent abdominal pain 42 Candida overgrowth 42 norepinephrine dopamine 42 restlessness irritability 42 Cohabiting 42 attention-deficit/hyperactivity disorder ADHD 42 alcohol addictions 42 Alzheimers disease 42 stiff achy joints 42 chronic illness 42 orofacial pain 42 GABA receptor 42 depressive disorder 42 Genital herpes 42 nighttime heartburn 42 yeast overgrowth 42 insomnia irritability 42 migraines 42 behavioral 42 Comorbid 42 hallucinations delusions 42 anhedonia 42 crippling shyness 42 pharmacological approaches 42 Frequent urination 42 unexplained fainting 42 SRBD 42 nerve degeneration 42 disorder ADD ADHD 42 Gamanon 42 Lyme arthritis 42 schizophrenia 42 REM sleep behavior 42 disorder ADHD 42 borderline personality 42 disorder FSAD 42 chronic halitosis 42 avoidant 42 emotional dysregulation 42 vulvar pain 42 hypersomnia 42 affective disorders 42 unipolar depression 42 irritability insomnia 42 prodromal phase 42 behavioral modification 42 self mutilation 42 grandiose delusions 42 neurologic disorder 42 vagus nerve stimulation 42 fatty liver disease 42 germ phobia 42 biofeedback therapy 42 Generalized Anxiety Disorder 42 narcissism 42 dopamine signaling 42 nonverbal behaviors 42 headaches stomachaches 42 Von Willebrand disease 42 Agreeableness 42 hyperphagia 42 Anorexia nervosa 42 Attention-Deficit/Hyperactivity Disorder 42 hyperexcitability 42 polycystic ovarian syndrome PCOS 42 pathological gambling addiction 42 dopaminergic 42 nondrug approaches 42 hypomania 42 depression suicidal thoughts 42 psychomotor agitation 42 eating disorder 42 obsessive jealousy 42 psychiatric comorbidity 42 eustress 42 Mental Disorders DSM IV 42 Personality traits 42 internalized homophobia 42 overeat 42 Cognitive Behavioural Therapy 42 personality disorders 42 hyperacusis 42 disorder posttraumatic stress 42 galanin 42 bupropion Zyban 42 sexual predation 42 schizoaffective disorder 42 BIID 41 mania hypomania 41 opiate receptors 41 Hormonal imbalance 41 Picky eating 41 psychoanalytic psychotherapy 41 Calorie restriction 41 sociopathic tendencies 41 Restlessness 41 acne breakouts 41 sexsomnia 41 narrowed airways 41 suicidal tendencies 41 glutamate signaling 41 excessive sleepiness 41 lovesickness 41 Parkinson disease neurodegenerative disorder 41 Diabetic neuropathy 41 mood swings 41 ringxiety 41 borderline personality disorders 41 psycho stimulant 41 ingestive behavior 41 aberrant behaviors 41 erectile dysfunction 41 migraine sufferer 41 psychopathologies 41 Hoarseness 41 horniness 41 librium 41 Uncontrolled diabetes 41 Anti depressants 41 rhythm disturbances 41 dystonia neurological movement 41 stereotypic behavior 41 dopamine receptors 41 Grief Share 41 Antabuse 41 PharmacoSurgery TM platform 41 osteoporosis brittle bones 41 Impulsiveness 41 neural mechanisms 41 Neuroticism 41 HPA axis 41 OCD sufferers 41 psycho physiological 41 Ritalin stimulant 41 Asperger 41 mood swings irritability 41 pharmacological therapy 41 lichen planus 41 avoidant personality disorder 41 Requip 41 alexithymia 41 Workaholics Anonymous 41 binge eater 41 neurocognitive impairment 41 dopamine depletion 41 Marital bliss 41 hedonic treadmill 41 psychoactive drugs 41 sadistic tendencies 41 avoidant attachment style 41 developmental trajectories 41 Aspergers 41 involuntary muscle contractions 41 menstrual cramps 41 disinhibiting 41 inhibiting dopamine 41 complex neurobiological disorder 41 psychotic symptoms 41 Tourette syndrome TS 41 dentinal hypersensitivity 41 tanorexia 41 major depressive disorder 41 Shy Drager syndrome 41 parkinsonian 41 DRD4 gene 41 Premarital counseling 41 opioid dependence 41 hyperhidrosis 41 Dystonia 41 Temporal lobe epilepsy 41 hallucinations paranoia 41 paranoid hallucinations 41 paranoid ideation 41 delayed CINV 41 neurological disorder characterized 41 Robi Ludwig 41 nongamblers 41 Premenstrual Dysphoric Disorder 41 Nalmefene 41 pseudotumor cerebri 41 dopamine antagonists 41 bi polar disorders 41 Prader Willi syndrome 41 neurologic symptoms 41 excessive urination 41 neuropsychological functioning 41 bingeing 41 Asberger Syndrome 41 Sciatica 41 Gestational diabetes 41 Oedipus complex 41 ictal 41 overactivity 41 vasovagal syncope 41 GAM ANON 41 schoolyard bullying 41 Mindfulness 41 romantic breakups 41 hippocampal function 41 esophageal sphincter 41 psychopharmacologic 41 substance abusers 41 irritable bowel syndrome IBS 41 compulsive overeater 41 hallucinations seizures 41 antidepressant medication 41 boredom 41 Major Depressive Disorder 41 generalized epilepsy 41 Self medicating 41 Hypoglycemia 41 Epileptic seizures 41 Dopamine agonists 41 dissociative disorders 41 Panic Attacks 41 neuropsychiatric symptoms 41 gastro esophageal reflux 41 opiate dependence 41 Xanax alprazolam 41 Sexaholics Anonymous 41 suicidal ideation 41 autistic traits 41 painful genital sores 41 temporomandibular disorders 41 Anorexics 41 vaginismus 41 chronic worriers 41 prescription narcotic hydrocodone 41 schizotypal personality disorder 41 systematic desensitization 41 epilepsies 41 dysphoric mood 41 obsessions 41 Stressful situations 41 opiod 41 clinically depressed 41 neuroleptic 41 EDNOS 41 Ms Hollonds 41 hyperactivity distractibility 41 Canker sores 41 irritability mood swings 41 epileptic fits 41 Bingeing 41 Asberger 41 psychotic delusion 41 inattention impulsivity 41 Self esteem 41 oppositional defiant disorder 41 Irritable Bowel Syndrome 41 overexercising 41 hallucinations psychosis 41 obstructive sleep apnea hypopnea 41 depression irritability 41 circadian rhythm sleep 41 NUCYNTA TM 41 casual flings 41 biopsychosocial model 41 relapse 41 chromosomal disorder 41 healthful lifestyle 41 hypomanic episodes 41 psychic numbing 41 Nicotine Anonymous 41 diagnosing bipolar disorder 41 Impulsivity 41 anosognosia 41 Halitosis 41 OCD sufferer 41 Chronic pain 41 genetically predetermined 41 Kay Redfield Jamison 41 Mood swings 41 compulsively 41 Problem gamblers 41 premenstrual symptoms 41 codependence 41 CART peptides 41 overindulgence 41 Stigmas 41 neurohormones 41 Pervasive Developmental Disorder 41 unhealthy eating habits 41 Overcomers 41 sleep disorder narcolepsy 41 DEPRESSION SUPPORT GROUP 41 dieting 41 overeats 41 ADD Attention Deficit Disorder 41 Sexual dysfunction 41 cystic acne 41 narcissistic personality 41 bipolar affective disorder 41 confusion disorientation 41 diagnosable disorder 41 celiac sprue 41 premenstrual dysphoric disorder PMDD 41 platonic friendships 41 dukkha 40 Postpartum depression 40 Hutchinson Gilford progeria 40 perfectionism 40 chronic insomnia 40 antisocial 40 fatigue syndrome 40 hallucinations 40 Mental illnesses 40 Interstitial cystitis 40 underlying pathophysiology 40 aberrant behavior 40 Vitamin B# deficiency 40 Technique EFT 40 Transcranial magnetic stimulation 40 electroconvulsive therapy ECT 40 Techniques EFT 40 somnolence sleepiness 40 Tourettes 40 Parkinsonism 40 Irritable bowel syndrome IBS 40 myoclonic seizures 40 appetitive 40 gamblers 40 drug misusers 40 medicalising 40 loneliness alienation 40 neurotransmitter GABA 40 dopamine D2 receptors 40 Eating disorders 40 tonic clonic seizure 40 incurable neurological disorder 40 multi infarct dementia 40 Suicidal tendencies 40 paranoid psychosis 40 arachnophobia 40 hypos 40 binge purge 40 bulimic 40 yo yo dieting 40 untreated sleep apnea 40 fibrodysplasia ossificans progressiva FOP 40 sleep bruxism 40 hypomanic episode 40 phonic tics 40 puerperal psychosis 40 polycystic ovary syndrome 40 decompensating 40 Distract yourself 40 tic severity 40 acedia 40 anandamide 40 Asperger's 40 constipation bloating 40 psychotic tendencies 40 induced psychosis 40 recessive trait 40 pharmacotherapies 40 depressive symptoms 40 PMDD 40 gambling 40 ketoacidosis 40 depression bipolar disorder 40 symptom flare ups 40 volitional 40 inoperable brain aneurysm 40 Disulfiram 40 bipolar mood swings 40 psychopathology 40 antidepressive 40 marital strife 40 nocebo effect 40 polyuria 40 Alzheimer dementia 40 habitual snoring 40 Alzheimer disease 40 psychoactive effects 40 serotonin deficiency 40 uncontrollable urge 40 pharmacological intervention 40 endogenous opioids 40 self hypnosis 40 induced analgesia 40 frequent tanners 40 Al Ateen 40 sexual perversions 40 affluenza 40 Addictions 40 licentious behavior 40 therapy CBT 40 drunkorexia 40 behavior 40 Enlarged prostate 40 Stressors 40 Nasal congestion 40 Coeliac disease 40 Prostatitis 40 socially undesirable 40 hypnotherapy 40 Merely associating 40 PTEN mutations 40 Sleepiness 40 TMJ disorders 40 juvenile myoclonic epilepsy 40 BPPV 40 untreated mental illness 40 headaches backaches 40 moodiness 40 somatoform 40 substance abuser 40 orbital frontal cortex 40 Tinnitus 40 al anon.alateen.org 40 tic disorders 40 Chronic migraine 40 self destructive 40 injurious behavior 40 symptomology 40 eating compulsively 40 arterial thickening 40 emotional arousal 40 euthymic patients 40 Suicidal ideation 40 AV conduction 40 parasocial relationships 40 hyperglycaemia 40 anxiolytic 40 traumatic childhoods 40 depressive