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(Click for frequent words.) 74 genomic DNA 71 cDNA libraries 70 amplicons 69 rRNA 69 biotinylated 69 contigs 69 cDNAs 69 amplicon 68 transcriptome 68 #S rRNA 68 mRNA 68 cDNA library 68 PCR amplification 67 kilobase 67 lysates 66 cytosolic 66 #S rRNA gene 66 #S rDNA 66 shRNA 66 ssDNA 66 At#g# 66 lentiviral 66 mRNA transcripts 66 dsDNA 66 Sanger sequencing 65 diploid 65 lysate 65 SDS PAGE 65 EGFP 65 transfected cells 65 viral RNA 65 orthologs 65 hTERT 65 exonuclease 65 short hairpin RNA 65 Supplementary Fig 65 constitutively 65 Saccharomyces cerevisiae 65 murine 64 RNA transcripts 64 methylated DNA 64 exon 64 transgene 64 transfected 64 dsRNA 64 kilobases 64 alternatively spliced 64 transfection 64 iNOS 64 operon 64 lacZ 64 mRNAs 64 short hairpin RNAs 64 fluorescently labeled 64 centromeric 63 dinucleotide 63 HEK# cells 63 budding yeast 63 ChIP seq 63 GAPDH 63 annexin V 63 thymidine 63 noncoding RNA 63 fission yeast 63 intron 63 VSV G 63 cDNA clones 63 luciferase 63 genomic loci 63 microarray experiments 63 mitochondrial gene 63 S. cerevisiae 63 RNA sequences 63 chromosomal DNA 63 oligo 63 nucleotide sequence 63 HepG2 cells 63 endonuclease 63 transcriptomes 63 cDNA sequencing 63 N. benthamiana 63 exons 63 transgene expression 63 RANTES 63 array CGH 62 heterochromatic 62 A. thaliana 62 microsatellite markers 62 ncRNA 62 homodimer 62 metaphase 62 COL#A# 62 nucleotide sequences 62 genes encoding 62 fluorophore 62 Illumina Solexa 62 gene amplification 62 RNA sequencing 62 epitope 62 BAC clones 62 subcellular localization 62 transcriptome sequencing 62 nuclease 62 RT qPCR 62 Rap1 62 chromatin immunoprecipitation 62 glycoproteins 62 tyrosine phosphorylation 62 immunoblotting 62 cDNA clone 62 transcriptional activation 62 yeast Saccharomyces cerevisiae 62 bacterial genomes 62 rDNA 62 miRNA 62 cathepsin B 62 mtDNA 61 enzymatic activity 61 tumor specific antigen 61 oligonucleotide 61 homologous recombination 61 cytochrome b 61 replicon 61 plasmid DNA 61 ChIP Seq 61 overexpressing 61 cell lysates 61 Cre recombinase 61 PCR primers 61 intronic 61 viral genome 61 CHO cells 61 untranslated regions 61 Immunohistochemical analysis 61 DNA polymerase 61 indel 61 polypeptide 61 deacetylation 61 transcriptome analysis 61 serine threonine kinase 61 gDNA 61 splice variant 61 uracil 61 Solexa sequencing 61 Annexin V 61 cell lysis 61 RNA polymerases 61 coding sequences 61 hybridomas 61 telomeric 61 oligonucleotide probes 61 virulence genes 61 intergenic 61 FUS1 61 cRNA 61 substrate specificity 61 E#F# 61 immunofluorescence 61 homodimers 61 extracellular domain 61 IFN gamma 61 uPAR 61 methyltransferase 61 allelic 61 gag pol 61 polyadenylation 61 RNAs 61 mRNA molecules 61 situ hybridization 61 CpG 61 quantitative PCR 61 proteolytic cleavage 61 aCGH 61 adenoviral 61 ribosomal DNA 61 splice variants 60 heterodimers 60 phage 60 retroviral vector 60 Western blotting 60 peroxidase 60 avidin 60 peripheral blood mononuclear 60 cytidine 60 luciferase gene 60 amino terminal 60 Phylogenetic analysis 60 S. pombe 60 PBMCs 60 DNase 60 5 hmC 60 polymerases 60 affinity purification 60 mRNA expression 60 TaqMan 60 UTRs 60 polypeptides 60 MTT assay 60 glycan 60 cell lysate 60 GSTP1 60 PCR amplified 60 isoform 60 replicase 60 linkage disequilibrium 60 qRT PCR 60 cells transfected 60 matrix metalloproteinase 60 gel electrophoresis 60 intergenic regions 60 tRNA 60 Drosha 60 homologs 60 clonally 60 isomerase 60 survivin 60 hepatocytes 60 nucleic acid molecules 60 EGF receptor 60 proteomic analysis 60 carcinoembryonic antigen 60 array comparative genomic 60 hepatocyte 60 erythrocytes 60 H#K# [002] 60 transduced 60 leukemic cell 60 virions 60 nucleolar 60 tumor antigen 60 Fig. 2A 60 transcriptionally 60 WT1 60 3'UTR 60 catenin 60 fusion protein 60 binding affinity 60 H#K#me# 60 condensin 60 PAX5 60 ciliated 60 cytokeratin 60 gene inactivation 60 miRNA expression 60 genomic sequence 60 Fig. 1C 60 neutralizing antibody 60 oligomer 60 Rab5 60 KLF4 60 CTCF 60 messenger RNA mRNA 60 immunoprecipitation 60 IGF2 60 outer membrane proteins 60 constitutively expressed 60 pyrosequencing 60 PCR assay 60 ubiquitination 59 yeast genome 59 siRNA duplexes 59 c myc 59 transient transfection 59 immunostaining 59 ESTs 59 MDCK cells 59 Genome Sequencer FLX System 59 3' 59 VNTR 59 microsomal 59 μL 59 affinity purified 59 human hepatocytes 59 VE cadherin 59 quantitative RT PCR 59 β cells 59 ^ sup #m 59 coactivator 59 mutant alleles 59 coexpression 59 TIMP 59 shRNAs 59 ligand binding 59 hepatoma 59 dimerization 59 beta galactosidase 59 oligos 59 protein encoded 59 coding genes 59 Fig. 1A 59 colorectal tumor 59 GS FLX Titanium 59 unmethylated 59 quantitative trait loci 59 #p# [003] 59 X. laevis 59 EphB4 59 GlcNAc 59 apical membrane 59 gp# [002] 59 TIMP 1 59 LC-MS/MS 59 phosphoprotein 59 amino acid substitutions 59 monocyte 59 reverse transcriptase 59 S. enterica 59 DGGE 59 phosphorothioate 59 mutagenesis 59 CD1d 59 nucleotide 59 kDa 59 transmembrane 59 wildtype 59 transmembrane protein 59 transmembrane receptor 59 eukaryotic 59 recombinant protein 59 Dicer 59 FLT3 59 lysine residues 59 RNA molecule 59 splice junctions 59 OCT4 59 exome 59 mRNA molecule 59 miRNAs 59 tetramer 59 RNA Seq 59 cysteines 59 guanosine 59 sequence homology 59 isoforms 59 TAp# 59 cytoplasmic 59 Haplotype 59 paralogs 59 phosphatidylinositol 59 peptide sequences 59 Clusterin 59 ORFs 59 transcriptomic 59 CD4 + T lymphocytes 59 coding exons 59 ribonucleic acid RNA 59 interfering RNAs 59 cDNA microarray 59 plasmid 59 mRNA Seq 59 prokaryotic 59 enzymatically 59 ligase 59 undifferentiated hESCs 59 miR #a [002] 59 PC3 cells 59 glycosylated 59 leukocyte 59 codons 59 mouse fibroblasts 59 transiently transfected 59 adduct 59 promoter methylation 59 cDNA synthesis 59 transferase 59 mitogen activated protein kinase 59 granulocyte 59 ligand 59 Transcriptome 58 site directed mutagenesis 58 amino acid sequence 58 immunofluorescence microscopy 58 ERK1 2 58 luciferase reporter 58 mutational analysis 58 bacterial genome 58 vascular endothelial cells 58 glycosyltransferase 58 valine 58 differentially expressed genes 58 polynucleotide 58 microarray 58 Fig. 1d 58 QPCR 58 centromere 58 RAD# [001] 58 μM 58 transactivation 58 secretory proteins 58 operons 58 antibody antigen 58 phosphate dehydrogenase 58 SOCS3 58 noncoding 58 plastid 58 multiplex PCR 58 μg ml 58 Fig. 1B 58 neutrophil 58 FFPE samples 58 mammalian cells 58 Supplementary Table 58 MEFs 58 RNA seq 58 CD# + [002] 58 6S RNA 58 transcriptional regulator 58 ribonuclease 58 beta actin 58 antigen 58 FRET 58 Jhdm2a 58 stably transfected 58 cytoplasmic domain 58 immunohistochemical 58 guanine G 58 proteomes 58 Overexpression 58 oligonucleotide microarrays 58 serine protease 58 heterologous 58 vimentin 58 microarrays 58 CCL#L# 58 ribosomal protein 58 ribozyme 58 qPCR 58 P selectin 58 CXCL# 58 epithelial cell 58 agarose gel electrophoresis 58 suppressor gene 58 ChIP chip 58 Pichia pastoris 58 aggrecan 58 Agrobacterium 58 Amino acid 58 plasmin 58 globin genes 58 proteolysis 58 orthologous 58 proteome 58 RT PCR 58 pyrimidine 58 Cyclin E 58 immunocytochemistry 58 organism genome 58 Fas ligand 58 RNA molecules 58 NFkB 58 Arabidopsis 58 Arabidopsis genes 58 inducible 58 RNA 58 tetramers 58 DNA sequences 58 granzyme B 58 #T# L1 58 ribosomal proteins 58 fluorescence detection 58 RRM1 58 chloroplast 58 centromeres 58 vitro cytotoxicity 58 nucleotide substitutions 58 keratinocytes 58 Arabidopsis genome 58 phosphorylated proteins 58 constitutively active 58 Gene Expression Assays 58 tumorigenicity 58 p# NTR 58 β 58 C#BL 6 mice 58 E3 ligase 58 peptide antigens 58 transcriptional regulation 58 DNA Polymerase 58 transgenes 58 chimeric protein 58 E1A 58 Xenopus laevis 58 membrane protein 58 reverse transcriptase polymerase chain 58 kinome 58 genomic sequences 58 gene sequences 58 tissue microarray 58 proto oncogene 58 kD 58 heterozygotes 58 cellulase 58 allelic variants 58 microarray analysis 58 globin 58 scFv 58 microRNA molecule 58 homology 58 phosphorylated 58 quantitative reverse transcriptase 58 messenger RNA 58 glucose transporter 58 IgG1 58 tRNA synthetase 58 cysteine residues 58 STAT1 58 PGCs 58 LRAT 58 nucleic acid sequence 58 mitochondrial 58 VEGF receptor 58 nM 58 maize genome 58 phospho 58 FGFR3 58 DNA demethylation 57 histidine 57 β galactosidase 57 immunoglobulin G 57 nucleases 57 situ hybridisation 57 T. brucei 57 SMN2 gene 57 potent inhibition 57 tyrosine kinase receptor 57 PDGFR 57 transgenic mice expressing 57 synuclein 57 triacylglycerol 57 immunoglobulin genes 57 Phosphorylation 57 histone acetylation 57 transmembrane domains 57 eIF4E 57 histone H3 57 μl 57 secreted proteins 57 HER2 protein 57 HLA DQ 57 Macrophage 57 thymocyte 57 proteolytic 57 MyD# 57 VEGFR2 57 germline 57 endocytic 57 colony stimulating factor 57 EF Tu 57 SNP genotyping 57 haplotype 57 carboxyl terminal 57 glycosylation 57 hybridoma 57 PrP 57 genotypic 57 Fig. 3a 57 tRNAs 57 Tetrahymena 57 mitochondrial DNA mtDNA 57 CYP#B# 57 chromatogram 57 downregulated 57 phagocytosis 57 massively parallel sequencing 57 transcriptome profiling 57 antisera 57 ectopic expression 57 F actin 57 beta globin gene 57 single nucleotide polymorphism 57 provirus 57 transcriptional 57 E. faecalis 57 thioredoxin 57 chloroplast genome 57 β1 57 mutant allele 57 receptor tyrosine kinase 57 genomic sequencing 57 downregulation 57 BeadChip 57 polymerase 57 TGF ß 57 shRNA libraries 57 kDa protein 57 fluorescence intensity 57 lysosomal 57 cultured cells 57 trans splicing 57 TNFR 57 MUC1 57 immunoreactive 57 sequenced genomes 57 deletion mutant 57 alleles 57 polyclonal 57 HCV replicon 57 prostate epithelial cells 57 homologous 57 comparative genomic hybridization 57 actinin 57 HLA DR 57 ncRNAs 57 Annexin 57 C#BL 6 57 transgenic rats 57 SNP arrays 57 deacetylase 57 adipogenic 57 fig. S2 57 ZFN 57 monomeric 57 supernatants 57 proteinase 57 aminopeptidase 57 ERBB2 57 BMP2 57 retrotransposon 57 overexpress 57 FasL 57 transcriptional profiling 57 antibody 57 phosphatase 57 proapoptotic 57 Sequencing System 57 hematopoietic progenitors 57 segmental duplications 57 5' triphosphate 57 RFLP 57 N Myc 57 gene encoding 57 syngeneic 57 leucine zipper 57 antiproliferative activity 57 clusterin 57 lysozyme 57 GenBank accession 57 noncoding RNAs 57 LNCaP cells 57 DEAR1 57 Drosophila genome 57 granulocytes 57 stably expressing 57 sequencing 57 genotypes 57 pseudogenes 57 MALDI TOF MS 57 Polymerase 57 MAP kinase 57 thymocytes 57 radiolabeled 57 mice lacking 57 RNA splicing 57 fig. S1 57 bispecific antibody 57 SMN2 57 antisense oligonucleotides 57 Plasmodium 57 HDAC6 57 chemiluminescence 57 translocates 57 RCAN1 57 nucleolin 57 immunohistochemistry IHC 57 peptoid 57 activin 57 amino acid residues 57 protein phosphorylation 57 caveolin 1 57 lectin 57 hybridoma cells 57 somatic mutations 57 Affymetrix GeneChip 57 embryoid bodies 57 protein 57 HSCs 57 ortholog 57 IGFBP 57 cyclin E 57 IRE1 57 SCD1 57 transcriptional profiles 57 Fig. 2C 57 IL #E 57 pDC 57 Xenopus 57 fluorescently tagged 57 heterochromatin 57 Supplemental Figure 57 physiologically relevant 57 Gag protein 57 triphosphate 57 hippocampal neurons 57 ligand receptor 57 α 57 CD# + [001] 57 TUNEL 57 ChIP 57 mRNA encoding 57 micro RNA 57 haplotyping 57 HGF 57 peptide 57 mannose 57 eIF2 57 HOTAIR 57 CD#c 57 nested PCR 57 BCR ABL 57 RNAi mediated 57 non coding RNA 56 keratinocyte 56 beta globin 56 mitochondrial genomes 56 mutant p# 56 lymphoid cells 56 PCR primer 56 IFN alpha 56 CD#b 56 Shp2 56 HDAC 56 RNA extraction 56 viral genomes 56 lipoxygenase 56 zebrafish embryos 56 transferrin 56 CHO K1 56 equimolar 56 JAK STAT 56 retroviral 56 5 methylcytosine 56 piggyBac 56 unmethylated DNA 56 heterozygosity 56 Cy3 56 Fig. 1a 56 genotyping 56 Histone 56 Nedd4 56 dimer 56 thymidine kinase 56 haploid 56 histone modification 56 chromatin immunoprecipitation ChIP 56 transcriptionally active 56 Fig. 3b 56 iTRAQ 56 stilbene 56 Germline 56 biochemical assays 56 homozygosity 56 ribosomal 56 TTR gene 56 presynaptic 56 tumorigenic 56 gene expression microarrays 56 mononuclear 56 alpha subunit 56 polyamine 56 trophoblast cells 56 reinhardtii 56 B. subtilis 56 CaM 56 streptavidin 56 c fos 56 gamma globin 56 Rad# 56 formalin fixed paraffin embedded 56 Monocyte 56 #S rRNA genes 56 SMN1 56 adhesion molecule 56 fig. S6 56 fluorochrome 56 vacuolar 56 OGG1 56 Foxp3 56 high throughput sequencing 56 cell adhesion molecule 56 analyte 56 megabases 56 hexose 56 CDK4 56 microglial activation 56 Fig. 1D 56 P. gingivalis 56 Arabidopsis thaliana 56 BMAL1 56 ultraconserved elements 56 TMPRSS2 ERG 56 ganglioside 56 hnRNP 56 nanomolar 56 trimer 56 number variation CNV 56 IFN α 56 microinjection 56 ChR2 56 CFTR cystic fibrosis transmembrane 56 quantitative PCR qPCR 56 lymphocyte 56 variant allele 56 eukaryotic cell 56 colocalization 56 subcellular compartments 56 defensin 56 phosphorylation 56 κ 56 peroxisomes 56 S#A# [002] 56 ApoB 56 EGFR receptor 56 DNA polymerases 56 leukemic cells 56 PDGF B 56 RNase L 56 enolase 56 HER2 receptor 56 ubiquitin ligase 56 extracellular domains 56 morphogen 56 cystic fibrosis transmembrane conductance 56 enterocytes 56 cyclin D1 56 DNA glycosylase 56 Oocyte 56 androgen receptor AR 56 differential gene expression 56 capillary electrophoresis 56 experimentally validated 56 DNA methyltransferase 56 vitro 56 BrdU 56 glyceraldehyde 3 56 glycan structures 56 proline 56 Alu elements 56 mediated phosphorylation 56 caspase 56 FFPE 56 CHO cell 56 Qdot 56 midgut 56 PKCi 56 siRNA 56 mesothelin 56 cytochrome c 56 C. jejuni 56 MSH2 56 aspartyl 56 kinase gene 56 RUNX3 56 focal adhesion kinase FAK 56 homolog 56 MALAT1 56 HERV 56 ribosomal RNA 56 TMPRSS2 ERG fusion 56 mitotic 56 IgG antibodies 56 PrPSc 56 MMP# 56 PLA2 56 adenoviral vector 56 immunohistochemical analysis 56 EGFR protein 56 transduction 56 beta amyloid peptide 56 DNA intercalator 56 fibroblast 56 Green Fluorescent Protein 56 pyruvate kinase 56 MAPK pathway 56 Akt1 56 BH3 56 NADPH 56 tropomyosin 56 alanine 56 FKBP# 56 β catenin 56 glycolytic 56 unmutated 56 reaction RT PCR 56 disulfide 56 TRAF6 56 cytokines IL 56 Nucleotide 56 Cyclin D1 56 PIP2 56 ERK2 56 trypanosome 56 carboxy terminal 56 idiotype 56 alveolar epithelial cells 56 EGFRvIII 56 glucan 56 glycoprotein 56 GLI1 56 viral antigen 56 overexpression 56 thyroglobulin 56 RASSF1A 56 desaturase 56 c Myc 56 gigabases 56 cytokine receptor 56 P. falciparum 56 missense mutation 56 multiplex polymerase chain 56 protein tyrosine phosphatase 56 gene expression profiling 56 KIAA# 56 cationic lipid 56 viral nucleic acids 56 SIRT2 56 heterologous expression 56 transfection efficiency 56 murine monoclonal antibody 56 siRNA mediated 56 isotype 56 MMP9 56 Ubx 56 gene expression 56 mRNA sequences 56 FMR1 56 oncoprotein 56 chromosome #q 56 protein fragment 56 p# [001] 56 K RAS 56 CEACAM1 56 piRNAs 56 PIP3 56 cytotoxicity 56 RNA ribonucleic acid 56 RAR beta 56 fibronectin 56 ubiquitinated 56 protein complexes 56 primordial germ cells 56 mycobacterial 56 C. albicans 56 haemagglutinin 56 cDNA sequences 56 Caenorhabditis elegans 56 pDCs 56 4E BP1 56 palladin 56 phenotype 56 Htt 56 archaeal 56 MyoD 56 flow cytometric 56 blastomeres 56 glioma cells 56 Typhi 55 p# MAPK 55 p# INK4a 55 genome annotation 55 small interfering RNA 55 β actin 55 nucleic acid 55 reproducibly 55 recombinant antibody 55 Transfection 55 RNase H 55 antisense RNA 55 apo AI 55 quantitation 55 RecA 55 Ca2 + 55 NF1 gene 55 bacterium Escherichia coli 55 NS3 55 reverse transcriptase RT 55 transcriptional repressor 55 vivo 55 EZH2 55 apolipoproteins 55 cytotoxicity assays 55 apoptotic 55 recombinase 55 mitochondrial genome 55 synthases 55 histone acetyltransferase 55 esterase 55 telomerase reverse transcriptase 55 receptor mediated endocytosis 55 BRAF protein 55 receptor kinase 55 loci 55 microdroplet PCR 55 RNase 55 IL #R 55 antigenic epitopes 55 uniparental 55 induced phosphorylation 55 Polymorphism 55 isogenic