allosteric

Related by string. Allosteric * * develops allosteric modulators . allosteric modulators . allosteric modulator . Allosteric modulation . positive allosteric modulator . allosteric modulator NAM . negative allosteric modulator . regarding allosteric modulators . allosteric modulator PAM . Addex allosteric modulation . Thus allosteric modulators . Allosteric modulators *

Related by context. All words. (Click for frequent words.) 72 SIRT2 70 PKC isoforms 68 mitogen activated protein kinase 68 serine protease 67 selective inhibition 67 #HT#A 67 PPARg 67 muscarinic 67 eIF4E 67 FKBP# 67 secretory pathway 67 Protein Kinase C 66 oligomerization 66 antiapoptotic 66 antiproliferative activity 66 serine threonine 66 pro angiogenic 66 potent inhibitors 66 Kv#.# 66 intercellular signaling 66 JAK#/JAK# 66 ligand binding 66 serine threonine kinase 66 chemokine receptor 66 occludin 65 deacetylation 65 anti apoptotic 65 glycosyltransferase 65 Histone 65 Nedd4 65 catenin 65 PAK1 65 sphingosine 1 65 histone deacetylase HDAC 65 CD# ligand 65 NKG2D 65 small molecule inhibitors 65 immunoregulatory 65 Cathepsin B 65 transcriptional repressor 65 transcriptional activation 65 cytokine signaling 65 receptor tyrosine kinase 64 EGF receptor 64 FGFR 64 peroxisome proliferator activated 64 protein kinase C 64 agonism 64 TNF receptors 64 phosphatidylinositol 3 64 PTP 1B 64 cytostatic 64 PDE4 64 LSD1 64 PDGFR 64 cytoprotective 64 VEGF receptor 64 M1 muscarinic 64 tubulin binding 64 Fc receptors 64 CRAC channel 64 proapoptotic 64 Eg5 64 HCV replication 64 glycosylated 64 intracellular signaling 64 LDL receptor 64 acetylcholine receptor 64 NFkappaB 64 p# MAPK 64 E#F# 64 c MET 64 topoisomerase II 64 melanocortin receptors 64 adenosine receptor 64 Signal transduction 64 site directed mutagenesis 64 partial agonists 64 cyclins 64 PI3 kinase 64 polyamine 64 mimetics 64 metalloenzymes 64 MAPK 64 Mcl 1 64 ubiquitin ligase 64 bicyclic 63 tyrosine phosphorylation 63 endocytic 63 S#P# 63 selective antagonists 63 MEK1 63 glutamate receptor 63 ERK1 2 63 EGFr 63 ubiquitin ligases 63 integrin receptors 63 vascular disrupting agents 63 estrogen receptor beta 63 TLR8 63 neurite outgrowth 63 cyclin dependent kinase inhibitor 63 nicotinic receptor 63 HIF 1a 63 anti CD3 63 RAS RAF MEK 63 somatostatin 63 5 lipoxygenase 63 thyroid hormone receptor 63 IL #p# 63 CpG 63 bacterial enzyme 63 partial agonist 63 PDGF receptor 63 CCR2 63 phosphatases 63 protein tyrosine phosphatase 1B 63 binding affinity 63 CD#b 63 PHD2 63 kinase pathway 63 acetylcholinesterase AChE 63 isoenzymes 63 thrombin receptor 63 paxillin 63 serotonin receptor 63 Nampt 63 potent anticancer 63 transferase 63 protein tyrosine phosphatase 63 trans splicing 63 secreted protein 63 proto oncogene 63 ligases 63 Hedgehog signaling 63 A3 adenosine receptor 63 glucocorticoid receptor 63 kinase domain 63 effector function 63 P#X# receptor 63 pRb 63 5 HT2A receptor 63 Anticalins ® 63 TrkA 63 TMEM#B 63 H#K#me# 63 nicotinic acetylcholine receptor 63 TNFα 63 inducible 63 bioactive lipids 63 miR #b [002] 63 phosphoinositide 63 potent inhibitor 63 histone deacetylase 63 TGF ß 63 AMPA receptor 63 molecularly targeted 63 prostaglandin synthesis 63 Anticalin ® 62 NR2B subunit 62 5 HT2B receptor 62 HMG CoA reductase 62 HER3 62 mTOR signaling 62 signaling cascades 62 anti proliferative 62 Vps# 62 IAP inhibitor 62 TGF beta1 62 amino terminus 62 proteolysis 62 Skp2 62 eNOS 62 c MYC 62 adipogenic 62 histone deacetylases 62 c myc 62 FGFR3 62 synthetic peptides 62 G Protein Coupled 62 cell adhesion molecule 62 cytochrome P# 62 6S RNA 62 PI3K/mTOR 62 dimeric 62 miR #a [002] 62 adrenergic receptors 62 HCV protease 62 aberrantly activated 62 pro apoptotic 62 amino acid substitutions 62 CDK inhibitor 62 related apoptosis inducing 62 guanylate cyclase 62 immunomodulating 62 receptor molecule 62 demethylase 62 chemokine 62 ß catenin 62 γ secretase 62 constitutively active 62 NF κB 62 protein tyrosine phosphatases 62 small molecule defensin 62 Fleximer 62 cyclic AMP cAMP 62 noncoding RNA 62 Abl 62 cyclooxygenase 62 IGF 1R 62 selectively inhibit 62 pyrimidine 62 hypoxia inducible factor 62 cortisol receptor 62 PDE1 62 P cadherin 62 receptor subtypes 62 specific lectin receptors 62 NFκB 62 GPx 62 tRNA synthetase 62 JAK STAT 62 potent antiproliferative 62 IL 1β 62 C5aR 62 Nicotinic 62 antisense oligonucleotide 62 potent inhibition 62 AT1R 62 pharmacokinetic interactions 62 FGF receptor 62 topoisomerase 62 P2X 62 HDAC inhibition 62 DNA methyltransferases 62 Upregulation 62 DNA demethylation 62 quinone 62 E3 ligase 62 ubiquitination 62 evolutionarily conserved 62 osteoblast differentiation 62 induce apoptosis 62 dopamine receptor 62 N methyl 62 MTP inhibitor 62 enzyme inhibitor 62 secretase 62 chromatin remodeling 62 PPAR gamma 62 micro RNAs 62 mediated apoptosis 62 peptidomimetic 62 bifunctional 61 Locked Nucleic Acid LNA 61 PLK1 61 antiangiogenic 61 Aurora kinase 61 dimerization 61 MT1 MMP 61 prolyl 61 EphB4 61 IGFBP2 61 carbohydrate polymer 61 prodrugs 61 phosphoprotein 61 ERK signaling 61 Galectin 61 Tubulin 61 peroxidase 61 Anticalins R 61 IgG1 61 KLF4 61 selective antagonist 61 inflammatory cytokine 61 cyclin dependent kinase 61 ERK pathway 61 miR# 61 adrenoceptor 61 polypeptides 61 acetylation 61 Vascular endothelial growth 61 cadherin 61 receptor gamma 61 FLT3 61 Integrin 61 V#F mutation 61 protein CETP 61 EGFR pathway 61 RANTES 61 ligand TRAIL 61 Kinases 61 therapeutically relevant 61 MEK ERK 61 sphingolipid 61 antagomirs 61 endogenous ligands 61 PI3K AKT 61 Wnt beta catenin 61 cyclin D1 61 proteolytic cleavage 61 osteogenic 61 NFAT 61 alpha subunit 61 chloride channels 61 downstream effector 61 transcriptional regulation 61 downregulated 61 #S proteasome 61 prostaglandin E2 PGE2 61 tumorigenicity 61 siRNA mediated 61 antisense oligonucleotides 61 heterodimers 61 uPAR 61 PI3K pathway 61 intracellular signaling pathways 61 tyrosine kinase 61 histone acetylation 61 TNFalpha 61 mediated inhibition 61 P#X# 61 VE cadherin 61 nAChR 61 acyl CoA 61 receptor PPAR 61 NMDA receptor 61 tumor vasculature 61 intracellular protein 61 MAPK pathway 61 PTPN# 61 FasL 61 ENaC 61 vascular endothelial 61 Polycomb 61 NFkB 61 Src 61 beta arrestin 61 T#M 61 costimulation 61 peptidic 61 neuroprotectant 61 MAP kinase 61 receptor mediated endocytosis 61 receptor subtype 61 cytokine receptor 61 ubiquitylation 61 deacetylase inhibitors 61 GLUT4 61 inverse agonist 61 A2A receptor 61 HDAC6 61 CD# receptor 61 ENMD # 61 electrophilic 61 AMACR 61 FGF2 61 transactivation 61 fast skeletal troponin 61 PcG 61 syntaxin 61 S1P 61 COX2 61 COX enzymes 61 efflux pumps 61 clinically validated targets 61 receptor binding 61 lipid soluble 61 soluble receptor 61 ErbB3 61 hypermethylation 61 adhesion molecule 61 chromatin structure 61 proteases 61 neuronal differentiation 61 Aurora Kinase 61 eicosanoid 61 5HT 61 hERG 61 Flt3 61 mitogenic 61 overactivation 61 FOXO3a 61 USP# 61 sigma receptors 61 TGF β 61 dopamine D2 61 antisense inhibitor 61 AChE 61 dephosphorylation 61 c myb 61 extracellular signal 61 EphA2 61 ligand 61 immune modulatory 61 phosphate S1P 61 apoptotic pathway 61 p#/CBP 61 tumor microenvironment 61 selective adenosine 61 GSK3 61 GABAB receptors 61 adrenergic 61 naturally occurring molecule 61 ligand receptor 61 novel peptide 61 5 HT1A 61 phosphorylates 61 Arp2 3 61 matrix metalloproteinases 61 lysophosphatidic acid LPA 61 bispecific 61 CPEB 61 DNA intercalator 61 GABAA receptor 61 nanomolar range 61 small molecule activators 61 5 HT2C 61 glucocorticoid receptors 61 Interferon gamma 61 transmembrane protein 60 DNA gyrase 60 H#K# [002] 60 antitumor 60 immunomodulatory effects 60 serine proteases 60 GPR# [001] 60 galectin 60 iRGD 60 mTOR inhibitors 60 Phosphorylation 60 neuromuscular junction 60 GSK3B 60 splice variant 60 lytic 60 LPA1 receptor 60 neurotrophic 60 TGF Beta 60 allosteric binding 60 inosine 60 Hypoxia Inducible Factor 60 TNFa 60 NKX#.# 60 proteolytic 60 beta subunit 60 NF kB pathway 60 liposomal formulation 60 phosphorylate 60 posttranslational modifications 60 PPARgamma 60 CTGF 60 receptor mediated 60 dehydrogenases 60 hydrolase 60 integrins 60 HDACs 60 pleiotropic 60 kinase enzymes 60 Immunohistochemical analysis 60 enkephalin 60 MDM2 60 transgene expression 60 RGD peptide 60 prostanoid 60 catalytic subunit 60 renal fibrosis 60 ERBB2 60 gamma secretase inhibitors 60 inhibit viral replication 60 nicotinic 60 irreversible inhibitor 60 osteoblast 60 postsynaptic 60 Integrins 60 IKKß 60 nucleotide binding 60 pigment epithelium derived 60 subtype selective 60 colony stimulating factor 60 factor Xa 60 Alfacell proprietary ribonuclease 60 SIRT1 enzyme 60 RANK Ligand 60 kinase substrate 60 coactivator 60 CCL# 60 cyclin E 60 opioid receptor 60 pyrimidines 60 endoplasmic reticulum stress 60 allosteric mechanism 60 caveolae 60 cathepsins 60 adenylate cyclase 60 voltage gated 60 immune stimulatory 60 apoptosis inducing 60 Rab# 60 casein kinase 60 homodimers 60 PI3K inhibitor 60 CD1d 60 mesenchymal cell 60 Ca2 + 60 VEGF signaling 60 Preclinical studies suggest 60 Sp1 60 Notch1 60 cyclooxygenase 2 60 antibody fragment 60 tumor suppressors 60 PI3K Akt 60 lipoxygenase 60 potently inhibited 60 incretin 60 glycolipids 60 GABA receptor 60 autocrine 60 receptor signaling 60 vasodilatory 60 GRP# 60 Annexin V 60 SGLT2 60 Factor VEGF 60 FGFs 60 #beta HSD 1 60 calcitonin gene related 60 protein kinases 60 CCX# 60 IGF1R 60 costimulatory 60 WT1 60 kinase 60 ribonuclease 60 oncogenic 60 NF kappa B 60 mRNA translation 60 tyrosine kinases 60 ErbB2 60 vanilloid receptor 60 pan HDAC inhibitor 60 tyrosine kinase receptor 60 nucleoside analogues 60 reverse transcriptase 60 highly selective inhibitor 60 cell adhesion molecules 60 phosphatidylinositol 60 fatty acid synthase 60 NF kappaB activation 60 signal transduction 60 signaling pathway 60 5 HT2A serotonin 60 galectins 60 muscarinic receptors 60 inhibitory 60 tumor suppressor protein 60 immunodominant 60 gastrin 60 heme oxygenase 60 messenger ribonucleic acid 60 anti angiogenic drugs 60 receptor kinase 60 transcriptionally 60 effector protein 60 cytidine 60 Fibroblast Growth Factor Receptor 60 nitric oxide synthase 60 TNF α 60 perivascular 60 transferrin receptor 60 arginase 60 sodium glucose cotransporter 60 thymidylate synthase 60 RNA silencing 60 Nanobodies 60 mecamylamine 60 cytolytic 60 Androgen receptor 60 histone deacetylases HDACs 60 exocytosis 60 druggable targets 60 S nitrosylation 60 Fas ligand 60 noncoding RNAs 60 SCD1 60 chimeric monoclonal antibody 60 cyclic peptide 60 immunostimulatory 60 focal adhesions 60 ligand binding domain 60 SGLT2 inhibitors 60 eotaxin 60 CDK9 60 GABAA 60 siRNA therapeutic 60 LRP6 60 inhibits protein synthesis 60 synthases 60 protein tyrosine 60 selective inhibitors 60 cysteine residue 60 homodimer 60 VIPR2 60 gene inactivation 60 messenger molecule 60 micro RNA 60 HDACi 60 antiproliferative 60 Runx2 60 directed mutagenesis 60 anti fibrotic 60 miR #a [001] 60 phosphodiesterase inhibitors 60 lipid rafts 60 receptors EGFR 60 lectins 60 PPARγ 60 ligands 60 PIP2 60 DNMT1 60 histone acetyltransferase 59 histone H3 59 microRNAs miRNAs 59 enzymatic pathways 59 ligand induced 59 glucokinase 59 TRPV3 59 glucose transporter 59 glycolytic 59 K + ATPase 59 STIM1 59 tetramer 59 acyltransferase 59 Antisense 59 ERK1 59 TET2 59 protein encoded 59 proteasome inhibitors 59 metalloprotease 59 pertussis toxin 59 untranslated regions 59 sphingomyelin 59 Cdc# 59 EGFR signaling 59 cell motility 59 cAMP dependent 59 PI3K/AKT 59 binding affinities 59 Onconase 59 phosphorylation 59 Dysregulation 59 mutational analysis 59 NS4A 59 novel immunomodulatory 59 antigen binding 59 Clusterin 59 vitro assay 59 MicroRNA 59 constitutively expressed 59 CDK5 59 TGF alpha 59 ribonucleoprotein 59 guanosine 59 CXCR2 59 RRM1 59 epithelial mesenchymal transition 59 splice variants 59 immunomodulation 59 IMPDH 59 galectin 3 59 plasminogen 59 monoclonal antibody mAb 59 hedgehog pathway 59 humanized monoclonal antibodies 59 proinflammatory 59 proteasome inhibitor 59 porphyrin 59 F actin 59 coexpression 59 CB2 receptor 59 hydroxylation 59 GPR# [002] 59 BAL# [001] 59 5 HT2A 59 peptidoglycan 59 transient receptor 59 NMDA antagonist 59 plasmin 59 apoptosis pathways 59 subcellular localization 59 GMX# 59 ZFPs 59 STAT1 59 histone modifications 59 tumorigenesis 59 59 autophagic 59 CEACAM1 59 sortilin 59 Receptors GPCRs 59 calcineurin 59 proline 59 geldanamycin 59 c Src 59 ligase 59 59 interferon IFN 59 Transcriptional 59 miRNA expression 59 PDZ domain 59 mTOR 59 receptor ligand 59 antitumoral 59 synthetic peptide 59 uricase 59 beta adrenergic 59 biosynthetic 59 basolateral 59 oxidase 59 cysteine 59 mRNA expression 59 inhibit angiogenesis 59 CaM 59 lysosomal 59 5 HT6 receptor 59 CB1 antagonists 59 morphogen 59 intron 59 selective modulator 59 RNase 59 anionic 59 tyrosine 59 TGFβ 59 intracellular 59 vasoactive 59 beta adrenergic receptors 59 meiotic recombination 59 ERa 59 #ME# 59 eIF2 59 downregulation 59 modulatory 59 PKC delta 59 gene transcription 59 IFN alpha 59 adrenergic receptor 59 GABAA receptors 59 nAChRs 59 phagocytosis 59 Microtubule 59 nucleic acid molecules 59 neoplastic transformation 59 topoisomerases 59 CCR9 59 phosphatase 59 axon guidance 59 mimetic peptide 59 tumorigenic 59 IL6 59 5alpha reductase 59 coactivators 59 VEGF receptors 59 TAp# 59 Fc receptor 59 proteoglycan 59 tropomyosin 59 Rb#/p# 59 MDR1 59 anti angiogenic 59 P gp 59 histone deacetylation 59 transcriptional regulator 59 APOBEC3G 59 BMP signaling 59 #HT#A receptor 59 kinase inhibitors 59 JAK1 59 CCR3 59 chemotactic 59 serotonin reuptake 59 Gamma secretase 59 bradykinin 59 covalently linked 59 adenosine receptors 59 N Myc 59 novel anticancer 59 sGC 59 isotype 59 calpain 59 cytokine receptors 59 HDAC2 59 4E BP1 59 Akt 59 Taxol ® 59 heterochromatic 59 platelet adhesion 59 cAMP signaling 59 IgG1 antibody 59 moieties 59 multitargeted 59 siRNA knockdown 59 virulence genes 59 polyadenylation 59 favorable pharmacokinetic 59 endonuclease 59 membrane receptors 59 receptor antagonists 59 FK# 59 receptors PPARs 59 tetramers 59 tyrosinase 59 potent antitumor 59 amino terminal 59 pre mRNA splicing 59 polymerase inhibitors 59 heparanase 59 ribosomal 59 effector functions 59 avidin 59 glial 59 RhoA 59 oncoproteins 59 BRAF kinase 59 glial cell 59 kinase inhibition 59 intra tumoral 59 peripherally acting 59 iNOS 59 XBP1 59 hydrolases 59 5 hydroxymethylcytosine 59 kinase enzyme 59 tubulin 59 glucagon receptor 59 endothelin receptor 59 Amino acid 59 Pentraxin 2 59 adipokine 59 substrate specificity 59 activatable 59 interleukin IL 59 bacterial virulence 59 peptide CGRP 59 lipopolysaccharide 59 receptor alpha 59 IL 1beta 59 RNAi pathway 59 Overexpression 59 anionic backbone 59 Protein kinase 59 Protein Kinase 59 epothilone 59 cyclin dependent kinases 59 HOTAIR 59 vivo 59 HER1 58 cytoplasmic domain 58 HDAC 58 immunomodulatory 58 MDSCs 58 Nucleic acids 58 BMP4 58 polyketide 58 transduce 58 soluble epoxide hydrolase 58 fibrogenesis 58 small molecule agonists 58 BCL2 58 HIV protease 58 disulfide 58 MUC1 58 MEK inhibitors 58 Cdc7 58 androgen receptor AR 58 mTOR mammalian target 58 phospholipid 58 paracrine 58 MEK inhibitor 58 sd rxRNA 58 vascular disrupting 58 norepinephrine reuptake inhibition 58 spectrin 58 glycosylation 58 hnRNP 58 subcellular 58 endonucleases 58 RAR beta 58 serpin 58 tumor angiogenesis 58 PDE#A 58 phospholipase 58 BMAL1 58 TRPV1 58 nucleolin 58 TLR agonists 58 mineralocorticoid receptor 58 anti amnesic 58 membrane protein 58 Tumor Necrosis Factor 58 receptor partial agonist 58 upregulates 58 GRK2 58 peroxynitrite 58 lymphangiogenesis 58 glutamate receptors 58 CGRP 58 tumor suppressive 58 oligomeric 58 PDGF alpha receptor 58 nucleosides 58 selective agonists 58 synaptogenesis 58 ErbB 58 cellular cytotoxicity 58 esterase 58 antigenic variation 58 transcriptional coactivator 58 Anticalins 58 selectively inhibits 58 NNRs 58 HIF PH 58 p# inhibitors 58 supramolecular 58 insulin sensitizing 58 Wnt signaling 58 antitumour 58 integrase 58 molecular biomarkers 58 survivin 58 beta lactamases 58 UsiRNAs 58 extracellular matrix ECM 58 TNFR 58 cytosolic 58 post transcriptional 58 activin 58 β1 58 Rac1 58 small molecule modulators 58 opioid receptor antagonist 58 p# subunit 58 single stranded oligonucleotides 58 cholesterol biosynthesis 58 targeted antifolate 58 adrenal hormone 58 VDAs 58 S#A# [002] 58 methyl D aspartate 58 Lyn kinase 58 FAAH 58 dioxygenase 58 endogenous ligand 58 Rap1 58 enzyme inhibitors 58 drug metabolizing enzymes 58 ghrelin receptor 58 Foxp3 58 tumor antigen 58 opioid receptors 58 operon 58 benzimidazole 58 mu opioid receptors 58 self assembled monolayers 58 antisense molecules 58 alkylating 58 druggable target 58 intramolecular 58 vivo RNAi 58 pyrophosphate 58 endothelial nitric oxide synthase 58 vitamin D receptor VDR 58 boronic acid 58 stem cell pluripotency 58 mTOR signaling pathway 58 plectasin 58 Kinase 58 granzyme B 58 beta tubulin 58 regulated kinase ERK 58 cyclin 58 ER alpha 58 adduct 58 CXCL5 58 humanized antibody 58 keratinocyte 58 polyketides 58 actin polymerization 58 EP1 receptor 58 peptide MHC 58 Hedgehog signaling pathway 58 Epidermal Growth Factor Receptor 58 TLE3 58 constitutively 58 ncRNA 58 telomerase reverse transcriptase 58 synthetic siRNA 58 IL 1ß 58 phosphorylated 58 retinoic acid receptor

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