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(Click for frequent words.) 78 proprietary siRNA sequences 65 siRNA sequences 64 siRNA molecules 64 lipid nanoparticles 64 AtuRNAi 63 siRNA therapeutic 61 antagomirs 61 rxRNA compounds 61 CXCR4 receptor 61 siRNA delivery 60 recombinant antibody 60 rxRNA TM compounds 60 sd rxRNA 59 rxRNA ™ compounds 59 LNP formulations 59 membrane receptors 59 Anticalins R 59 humanized monoclonal antibodies 59 UsiRNAs 59 Protein Kinase C 58 antisense oligonucleotides 58 rxRNA 58 DiLA2 58 lentiviral vectors 58 integrin receptors 58 PROfusion 58 liposomal 58 molecular abnormalities 58 Curaxin 58 dAbs 58 Anticalins ® 58 RNA antagonist 58 sd rxRNA compounds 57 M2 subunit 57 anti CD3 57 nucleic acid molecules 57 Cyclosert TM 57 DNA oligonucleotides 57 liver hepatocytes 57 AtuPLEX 57 Locked Nucleic Acid LNA 57 Cyclosert 57 monoclonal antibody mAb 57 fusion proteins 57 Receptors GPCRs 57 transfection reagents 57 mda 7 57 Fibroblast Growth Factor Receptor 57 selective kinase inhibitors 57 biologic therapeutics 57 RNAi compounds 57 CoVal TM fusion 57 splice variant 57 engineered RAP peptides 57 siRNA compounds 57 MDRNA proprietary 57 CRAC channel 56 RNAi therapeutic 56 DiLA2 Platform 56 sphingolipid 56 HepDirect prodrug 56 cationic lipids 56 MEK inhibitors 56 Epidermal Growth Factor Receptor 56 antimitotic 56 Fleximer 56 small molecule inhibitors 56 A3 adenosine receptor 56 ANGPTL4 56 nanomedicines 56 liposomal delivery 56 proteasome inhibitors 56 peptide inhibitors 56 DNA methyltransferases 56 metalloenzymes 56 mAbs 56 Activating mutations 56 AAV vectors 56 benign neoplasms 56 splice variants 56 sirtuin therapeutics 56 Cdc7 56 Calando proprietary 56 anionic backbone 56 prodrugs 56 Curaxins 56 radionuclide therapy 56 small molecule activators 56 therapeutics 56 secreted proteins 56 short interfering RNA 56 non coding RNA 56 acetylcholinesterase AChE 56 #beta HSD1 56 novel peptide 55 histone deacetylase HDAC 55 viral vectors 55 TLR agonists 55 lipidoid 55 immunoregulatory 55 FGFR 55 SMARTICLES ® 55 small molecule activator 55 molecularly targeted 55 Gamma secretase 55 siRNAs targeting 55 humanized antibody 55 polyketide 55 intracellular protein 55 virus AAV 55 RONDEL TM 55 HDAC6 55 siRNA therapeutics 55 peptides proteins 55 multiplexed assays 55 immunotoxin 55 biased ligands 55 efflux pump 55 vitro assay 55 AvalonRx R 55 molecular biomarkers 55 therapeutic monoclonal antibodies 55 p# subunit 55 ESBA# 55 nucleases 55 Novosom 55 small interfering RNA 55 vascular disrupting agents 55 androgen receptor AR 55 receptor ligand 55 inhibit viral replication 55 p# inhibitor 55 serine proteases 55 tumor antigens 55 short hairpin RNAs 55 γ secretase 55 HepDirect R 55 polyketides 55 USP# 55 tkRNAi technology 55 oncolytic viruses 55 chemotherapeutics 55 Electroporation 55 siRNA constructs 55 proliferative diseases 55 serine protease 54 Monoclonal 54 peptide antigens 54 optimized siRNA 54 IgGs 54 Intradigm 54 Alfacell proprietary ribonuclease 54 PORxin 54 Phylomer 54 Factor Receptor 54 enzymatic pathways 54 NF KB 54 TTR gene 54 detection reagents 54 ErbB3 HER3 54 Enkephalin 54 pRb 54 interferon lambda 54 telomerase inhibitor 54 siRNA 54 AMPK activators 54 KinomeScan 54 DNA plasmids 54 Kinases 54 vitamin D analogs 54 DNAi 54 glycolipids 54 protein biosynthesis 54 peptide therapeutics 54 antiviral compounds 54 Phylomer ® 54 tRNA synthetases 54 anticancer therapeutics 54 GPCR targets 54 Nanobodies 54 platinum chemotherapeutic 54 MediVas 54 inactivating mutations 54 endogenous ligands 54 recombinant antibodies 54 antisense molecules 54 granzyme B 54 nanoparticle aggregates 54 Litx 54 enzyme inhibitors 54 nucleosides 54 Dicer Substrate 54 siRNA conjugates 54 lipid particles SNALP 54 peptidomimetic 54 biologic therapies 54 orphan GPCRs 54 multiplex assay 54 carbohydrate compounds 54 miR #a [002] 54 Clusterin 54 immunotherapeutics 54 anticancer therapies 54 ANTISENILIN ® 54 adipogenic 54 ankyrin repeat 54 JAK2 inhibitors 54 Tekmira SNALP technology 54 oligonucleotides 54 vivo RNAi 54 T#M 54 TSLP 54 ZFP TF 54 pyrimidines 54 generation siRNA sequences 54 epigenetic regulation 54 5 HT2A serotonin 54 telomerase inhibitors 54 Tekmira lipid nanoparticle 54 Nucleic acids 54 anticancer agents 54 biotherapeutic 54 genomic proteomic 54 Adnectin 54 tubulin inhibitor 54 Locked Nucleic Acid 54 Wnt signaling pathway 54 mGluR2 NAM 54 CD# ligand 53 siRNA mediated 53 keratinocyte 53 isoform selective 53 Elastin 53 polymersomes 53 catalytic antioxidant compounds 53 synthases 53 situ gelling 53 maturation inhibitors 53 clinically validated targets 53 histone deacetylase inhibitors 53 orally bioavailable mimics 53 monoclonal antibody MAb 53 stapled peptides 53 proteins peptides 53 NEUGENE 53 vivo potency 53 Dystrophin 53 MolecularBreeding 53 transduce 53 assay kits 53 alpha#beta# integrin 53 ligand induced 53 SNALP formulation 53 phosphoprotein 53 Tumor Necrosis Factor 53 CB2 receptor 53 transcriptomics proteomics 53 5 hydroxymethylcytosine 53 Nanobodies ® 53 IAP inhibitor 53 Nektar proprietary 53 VEGF receptor 53 JAK kinases 53 NTDDS 53 TRIOLEX HE# 53 proprietary polysaccharide 53 IL #R 53 cathepsins 53 selective inhibition 53 ligases 53 polyclonal antibody 53 PI3K AKT 53 C5aR 53 BRAF kinase 53 Dicer Substrate Technology 53 auristatin 53 methylation markers 53 biocompatible polymers 53 GelSite R polymer 53 regulate therapeutically important 53 eicosanoid 53 effector molecules 53 inhibiting tumor 53 cytoprotective 53 RNA antagonists 53 druggable targets 53 bispecific 53 stem cell pluripotency 53 immunogens 53 small molecule modulators 53 humanized monoclonal 53 pharmacodynamic biomarkers 53 novel immunotherapeutic 53 silico prediction 53 defensins 53 cytidine 53 KL4 surfactant 53 immunotherapeutic approaches 53 matrix metalloproteinases 53 mechanistic insights 53 selective antagonists 53 lung epithelial cells 53 cellular immunotherapy 53 peptidic 53 trans splicing 53 RXi sd rxRNA compounds 53 oral transdermal 53 anti angiogenic agents 53 therapeutic monoclonal antibody 53 nanoviricides 53 IL #p# 53 novel RNAi therapeutics 53 therapeutic peptide 53 PI3K/mTOR 53 RNAi therapeutic targeting 53 iRGD 53 glycosyltransferase 53 prophylactic vaccines 53 Adnectins 53 intermediate filament 53 CARBOSOME TM formation 53 Hsp# inhibitors 53 multiprotein complex 53 antibody fragments 53 DsiRNA 53 biocatalysts 53 MDMX 53 targeting PCSK9 53 oncolytic virus 53 DURECT proprietary 53 cancer therapeutics 53 metabolomic profiles 53 Integrins 53 potently inhibit 53 GeneICE 53 epigenetic therapeutics 53 VitiGam 53 Factor VIIa 53 CDDO Im 53 immune modulating 53 Photodynamic therapy PDT 53 Systemic Delivery 53 isoform selective inhibitors 53 anti CD# antibodies 53 NMDAR 53 LentiVector 53 MEK ERK 53 JAK3 53 TÎ ² 4 53 fibrotic disease 53 PDGF receptor 53 meganucleases 53 RONDEL ™ 53 engineered proteases 53 SNALP 52 P#X# 52 kinase inhibitors 52 poly ADP ribose polymerase 52 buccal delivery 52 biologic pathway 52 potent inhibition 52 HCT# 52 extracellular matrix ECM 52 IGFBP2 52 proprietary Dicer Substrate Technology 52 isoprenoid 52 taxane derivative 52 potent cytotoxic 52 KL4 Surfactant 52 effector functions 52 angiogenic responses 52 cellular organelles 52 secretase 52 mGluR5 antagonist 52 TLR8 52 AEG# 52 LNPs 52 metalloprotease 52 HER2 HER3 52 Anticalins 52 DNA gyrase 52 transmembrane proteins 52 Liposomal 52 antisense oligonucleotide 52 ddRNAi 52 molecular chaperone 52 bispecific antibody 52 AAV vector 52 lipid nanoparticle 52 transgenic mouse models 52 immunoregulation 52 PI3 Kinase 52 MAbs targeting 52 potent inhibitors 52 MTP inhibitor 52 2DG 52 ERK pathway 52 tumor vasculature 52 CRTH2 52 act synergistically 52 genotyping gene expression 52 DNA intercalator 52 HER1 52 endosomal release 52 lentiviral vector 52 Fibroblast 52 albumin binding 52 ACTCellerate 52 diagnostic biomarkers 52 microRNA miRNA 52 enveloped viruses 52 Oligonucleotide 52 NeoLipid R 52 proprietary LNA 52 aptamers 52 Histone deacetylase 52 cardiac myocyte 52 peptide fragments 52 CCR3 52 diagnostic biomarker 52 biotherapeutics 52 GMX# 52 hormone gastrin 52 protein receptors lectins 52 HSP# inhibitors 52 pRNA 52 ENMD # 52 Aptamer 52 antisense inhibition 52 MAPK pathway 52 antisense RNA 52 endophenotypes 52 glial derived neurotrophic 52 biology medicinal chemistry 52 mTOR inhibitors 52 VEGF pathway 52 cGPS ® 52 Abeta peptide 52 SIRT1 gene 52 thapsigargin 52 protein misfolding 52 Hypoxia Inducible Factor 52 preclinical compounds 52 unnatural amino acids 52 RNAi therapeutics 52 UCOE 52 TGR5 52 cytokine signaling 52 Zysolin TM 52 AFFiRiS 52 drug zotarolimus 52 BRAF protein 52 effector protein 52 dendritic spine 52 delivered RNAi therapeutic 52 vivo fluorescence imaging 52 ribonuclease 52 NKG2D 52 Alu RNA 52 HuCAL R 52 myelofibrosis polycythemia vera 52 Pentad TM 52 TRIM5a 52 Nanobody ® 52 FLIPR 52 electro optic plastics 52 selectively induce apoptosis 52 RNA silencing 52 toxic amyloid beta 52 liposomal formulations 52 siRNA duplexes 52 sclerostin 52 Tissue Factor 52 insoluble plaques 52 kinase assay 52 selective kinase inhibitor 52 glycosylated 52 anti miRs 52 bioactive molecules 52 PI3K inhibitors 52 cytotoxic agents 52 tkRNAi 52 antisense inhibitors 52 Arp2 3 52 small molecule 52 intracellular accumulation 52 Huntingtons disease 52 epothilones 52 peptoid 52 ALK inhibitors 52 NS4A 52 lipid nanoparticle LNP 52 thymidylate synthase TS 52 macrocyclic lactone 52 NF kB Decoy 52 immunologic diseases 52 anti CD# antibody 52 NS#/#A protease 52 OXIGON TM 52 c MET 52 Tr DNA 52 NeuroTrans TM 52 intracellular signaling pathways 52 proprietary biomaterials 52 bispecific antibodies 52 nanocarriers 52 JAK1 52 Aurora kinase 52 PPARγ 52 tumor suppressors 52 sphingolipids 52 antisense drugs 52 Interferon alpha 52 PTP 1B 52 stem cell therapeutics 52 Nanobody 52 antisense compounds 52 RayBiotech 52 Sertoli cell 52 selectively inhibit 52 recombinant plasma 52 CYT# potent vascular disrupting 52 aptamer therapeutics 52 protein antigens 52 immunostimulatory 52 enabled ARIUS 52 GPx 52 oligonucleotide probes 52 intercellular signaling 52 osteogenic 52 LHRH antagonists 52 DXL TM 52 Fleximer R 52 post translational modifications 52 accumulate preferentially 52 Therapeutic antibodies 52 ErbB1 52 tenascin C 52 lysosomal enzyme 52 recombinant adeno associated 52 Angiocept 52 intracellularly 52 Neuropeptide Y 52 small molecule agonists 52 hESC derived 52 antitumoral 52 Signal transduction 52 MALDI-TOF/TOF 52 multimodality imaging 52 chimeric protein 52 EML4 ALK 52 neuroinflammation 52 SGLT2 inhibitors 52 JAK#/JAK# 52 radiolabeled antibodies 52 nonviral 52 nanocarrier 52 c myb 52 therapeutically relevant 52 NS4B 52 #T# L1 52 EGFR HER 52 synthetic peptides 52 gastric carcinomas 52 tests miRview TM 52 Flt3 52 ArQule Kinase Inhibitor Platform 52 bacterial enzyme 52 LTQ Orbitrap 52 binding affinities 52 beta globin gene 52 Viprovex TM 52 NF kB pathway 51 kinase inhibition 51 intermediate filaments 51 activate p# 51 Upregulation 51 conventional siRNA molecules 51 delta isoform 51 CaR 51 #ME# 51 isotypes 51 Hsp# inhibition 51 phosphate S1P 51 4E BP1 51 ligand binding 51 pro angiogenic 51 immunotherapeutic 51 hydrogel nanoparticles 51 interferon IFN 51 hES cells 51 endoglin 51 PathHunter 51 extracellular matrices 51 oncolytic 51 Preclinical studies suggest 51 novel anticancer 51 monoclonals 51 FGFR3 51 Western Blotting 51 ZFPs 51 TriGrid ™ 51 GPCRs 51 ErbB3 51 macrocycles 51 adenoviral 51 intranasal delivery 51 glucocorticoid receptors 51 anti infective treatments 51 PARP1 51 Symadex 51 nano encapsulation technology 51 histone deacetylases 51 synthetic siRNAs 51 FGFs 51 neuropilin 51 SIRT2 51 histone deacetylase inhibitor 51 MAbs 51 Corgentin 51 AKT inhibitor 51 retroviral vectors 51 protein quantitation 51 Transmembrane 51 Vascular Endothelial Growth 51 PARP inhibitors 51 calcium phosphate nanoparticles 51 aza anthracenedione molecular 51 MAP kinase 51 posttranslational modifications 51 theranostic 51 novel antiviral therapeutics 51 blood clotting proteins 51 therapeutically useful 51 transthyretin TTR 51 HDAC inhibition 51 cancer immunotherapies 51 mRNA sequences 51 aggregated Abeta 51 histone deacetylase 51 protein tyrosine phosphatase 51 Anavex #-# 51 nanodevices 51 proliferative disorders 51 single stranded oligonucleotides 51 MultiStat 51 juvenile chondrocytes 51 siRNA binds 51 selective inhibitors 51 VEGF receptors 51 BC SeraPro ™ 51 tiapamil 51 geldanamycin 51 AV HALT 51 Monoclonal Antibody 51 dimensional nanostructures 51 stimulate insulin secretion 51 ImmuneY2 51 HDAC enzymes 51 XL# XL# 51 Ligands 51 aptamer 51 miRNA expression 51 Chemokine Receptor 51 cytokine receptor 51 liposome formulations 51 CD# expressing 51 Smac mimetics 51 eIF 4E 51 thymosin beta 4 51 microRNA biomarkers 51 Interferons 51 Sindbis 51 protein biochips 51 Epidermal Growth Factor 51 shRNA libraries 51 glutamate receptors 51 CellPort Technologies 51 phage display 51 antigen receptors 51 ribonucleic acid RNA 51 Protease inhibitors 51 antineoplastic agents 51 lentiviral 51 silencing RNAs 51 antigen fusion 51 degrading enzymes 51 single molecule sequencing 51 EGFR pathway 51 antiproliferative effects 51 LNA TM 51 fibrin derived 51 HepDirect 51 neurotrophic factors 51 CD# antibodies 51 macrocyclic 51 Mucosal 51 SMaRT ™ 51 mitotic kinesins 51 targeted radiotherapeutic 51 affinity ligands 51 penetrating peptides 51 multitargeted 51 metalloproteinases 51 MCSP respectively 51 CDK inhibitor 51 neurodegenerative disorders 51 enzyme beta secretase 51 Janus kinase 51 uPAR 51 prostaglandin synthesis 51 p# mitogen activated 51 ETBs 51 transcytosis 51 antiapoptotic 51 DNA demethylation 51 cyto 51 protein tyrosine phosphatase 1B 51 cyclophilin D 51 GPR# [002] 51 sphingomyelin 51 RGD peptide 51 cleavable linker 51 Invader chemistry 51 ADME Tox 51 MMAE 51 mesothelial cells 51 monoclonal antibodies MAbs 51 #beta HSD 1 51 HeliScope Sequencer 51 SIRT1 activators 51 neoplastic transformation 51 optogenetic 51 PARP inhibition 51 trimeric 51 antisense therapies 51 PPARg 51 small molecule tyrosine 51 GAGs 51 proprietary PEGylation 51 vinca alkaloids 51 paxillin 51 viral proteins 51 lymphoid organs 51 progranulin protein 51 HER2 HER2 51 pathological hallmark 51 Alligator Bioscience 51 TNF receptors 51 prognostic markers 51 selective antagonist 51 NR2B subunit 51 antiangiogenesis therapies 51 Annexin A5 51 PKC enzyme 51 HDACs 51 mRNA antagonists 51 VDAs 51 matrix metalloproteases 51 neuro inflammatory 51 Stapled Peptides 51 nanopore sequencing 51 ERK2 51 tumor specific antigen 51 drug conjugate 51 TLR8 agonist 51 demethylating agent 51 IGF1R 51 ErbB receptors 51 uPA 51 nanocells 51 virulence factors 51 Pentraxin 2 51 ALN TTR 51 Tarvacin Anti Viral 51 enzyme inhibitor 51 intracellular uptake 51 Wnt beta catenin 51 Geniom 51 siRNA knockdown 51 Smac mimetic 51 adenosine receptor 51 monoclonal antibodies 51 NuMimetic TM 51 acetylcholine receptor 51 therapeutic modality 51 DepoVax TM 51 kappa opioid receptors 51 protein ADNP 51 nanoparticulate 51 vascular endothelium 51 HCV protease inhibitors 51 RNA siRNA 51 factor receptor FGFR 51 Glycoprotein 51 immune modulatory 51 glycan 51 ZFN 51 5 hmC 51 anti angiogenic drugs 51 HEK# 51 Protein Kinase 51 anticancer compounds 51 immunomodulatory properties 51 protein therapeutics 51 aminoglycosides 51 transcriptionally active 51 Integrase 51 DOS# 51 antibody fragment 51 SERMs 51 metabolite profiling 51 NNR Therapeutics 51 protease enzyme 51 primary cilia 51 Dicer Substrate siRNA DsiRNA 51 Sphingomab 51 nanoarrays 51 prolyl hydroxylase inhibitors 51 sd rxRNAs 51 tRNA synthetase 51 nAChRs 51 biomarker profiling 51 Tß4 51 biochemical assays 51 chemically modified siRNA 51 Metallophile ™ Technology 51 mineralocorticoid receptor 51 MDSCs 51 CCR1 51 conserved sequences 51 interfering RNAs 51 miRNA molecules 51 oncoproteins 51 GPR# agonist 51 chemotherapeutic treatments 51 mimetic compounds 51 uricase 51 radioprotective 51 glutamic acid decarboxylase 51 peptide ligands 51 glycosylation patterns 51 PRLX # 51 somatic mutations 51 cyclin dependent kinase inhibitor 51 non porcine pancreatic 51 biomarker assays 51 DGAT 51 bone morphogenetic proteins 51 GPI anchored 51 pathogenic mechanisms 51 Cathepsin B 51 protein ligand 51 adenovector 51 apoptotic pathway 51 tyrosine kinase receptor 50 anti mitotic 50 glycan structures 50 CCX# 50 viral inactivation 50 virulence genes 50 PDE4 modulators 50 HepDirect technology 50 peptides 50 deacetylase inhibitors 50 Qdot 50 RAF kinase VEGFR 50 siRNA nanoparticles 50 molecular determinants 50 ZFN TM 50 proteomic analysis 50 protein actin 50 DiLA2 platform 50 HER2 receptor 50 Aptocine 50 5 HT2C receptor 50 c Raf kinase 50 NF1 gene 50 Innate immune 50 transient receptor 50 signal transduction inhibitor 50 glycosylation profile 50 CDK4 50 multigenic 50 GPCR 50 prostacyclins 50 Transfection Reagent 50 histone deacetylases HDACs 50 stimulates collagen 50 broad applicability 50 targeted antifolate 50 SCD1 50 KRAS oncogene 50 Curaxin CBLC# 50 lysosomal storage diseases 50 novel therapeutics 50 G Protein Coupled 50 coupled receptors GPCRs 50 experimentally validated 50 recycling endosomes 50 RNA sequences 50 soluble proteins 50 GSK3B 50 DepoVax 50 Histone 50 MCF7 50 multiplex immunoassays 50 phagosomes 50 AvalonRx ® 50 TLR9 agonist 50 regulating gene expression 50 Affibody ® molecules 50 ribonucleoprotein 50 Th2 cytokines 50 FLT3 50 TriGrid 50 fatty acid biosynthesis 50 plasmid DNA pDNA 50 microRNAs miR 50 HDAC inhibitors 50 prostanoid 50 peptide conjugated 50 beta amyloid peptide 50 glutamyl 50 biased ligand 50 synergistic combinations 50 DGAT1 inhibitors 50 busulfan 50 cardiometabolic disorders 50 ghrelin receptor 50 HCV polymerase 50 Nanoshells 50 investigational monoclonal antibody 50 pharmacological chaperone 50 covalent drugs 50 IAP inhibitors 50 Extracellular Matrix 50 nanocapsules 50 selective HDAC inhibitors 50 Olig2 50 novel antibody therapeutics 50 RNAi therapeutic targeting PCSK9 50 Anticalin ® 50 Bendavia 50 synovial cells 50 Lauriad 50 thermostable 50 C3 convertase 50 alpha folate receptor 50 Platelet Derived Growth 50 fusion inhibitor 50 multiplex assays 50 nucleic acid sequencing 50 Oncogenic 50 ZFN technology 50 protein kinases 50 downregulates 50 secretory pathway 50 Cobalamin TM mediated 50 proprietary transdermal 50 p# pathway 50 selectively inhibiting 50 aptamers derives 50 Nedd4 50 NGPs 50 CBLC# 50 endostatin 50 MIF protein 50 HMGCR 50 thromboxane A2 50 nanomolar 50 sensory receptors 50 SMN1 50 vaccine adjuvant 50 anti inflammatory cytokine 50 Cathepsin S 50 Anticalin 50 favorable pharmacokinetic 50 gastrin 50 phosphorylated proteins 50 molecular chaperones 50 dimerization 50 HSP# inhibitor 50 beta amyloid fragments 50 bone morphogenetic proteins BMPs 50 Lpathomab 50 gene amplification 50 tumor antigen 50 OncoVEX 50 ncRNA 50 NeoLipid TM 50 Vidaza ® 50 VSV G 50 kidney urologic 50 siRNAs 50 intracellular pathogens 50 EphA2 50 peroxisomal 50 reverse transcriptase inhibitors