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(Click for frequent words.) 66 vitro ADME 65 pharmacokinetic pharmacodynamic 65 preclinical efficacy 65 vivo pharmacology 64 metabolite identification 63 predictive toxicology 63 pharmacodynamic PD 63 favorable pharmacokinetic profile 63 pharmacodynamic PK PD 63 PK PD modeling 62 pharmacokinetic 62 DMPK 62 comparative genomic 62 ADME 62 phenotyping 62 Pharmacokinetic 62 pharmacokinetic PK 61 genomic proteomic 61 metabolite profiling 61 ADME Tox 61 MetaBase TM represents 60 DiLA2 60 NEUGENE antisense 60 pharmacodynamic parameters 60 BioMAP 60 Blinatumomab 60 pharmacodynamic 60 Kahalalide F 60 vivo preclinical 60 pharmacodynamic endpoints 60 pharmacokinetics pharmacodynamics 60 Genedata Expressionist 60 Meta analyzes 60 toxicogenomic 60 genotypic 60 pharmacokinetics PK 60 therapeutic monoclonal antibody 60 PI3K/mTOR 60 TRV# [001] 60 uricase 60 pharmacodynamic markers 60 vivo 59 human microdosing 59 GMX# 59 Micromet BiTE 59 MDRNA proprietary 59 radezolid 59 biomarker identification 59 rxRNA 59 therapeutically relevant 59 toxicogenomics 59 Protein Expression 59 tkRNAi 59 bioanalysis 59 pharmacodynamic properties 59 Genomatix 59 Antiviral Activity 59 Illumina Solexa 59 Watson LIMS 59 bioprocesses 59 biodistribution 59 MGN# 59 histone deacetylase inhibitor 59 AAG geldanamycin analog 59 BACcel 59 ChIP chip 58 protein quantitation 58 vitro cytotoxicity 58 PCR primers 58 pharmacokinetic studies 58 NOD mouse 58 CellCiphr 58 SNP Genotyping 58 biophysical techniques 58 YONDELIS R 58 BAL# [001] 58 preclinical pharmacology 58 cGMP manufacture 58 rHuPH# 58 GLP toxicology 58 QSAR 58 busulfan 58 ENMD # 58 PORxin TM 58 Nonclinical 58 quantitative proteomics 58 orally bioavailable 58 Cytotoxic 58 DermaVir Patch 58 novel peptide 58 isatoribine 58 Deforolimus 58 pharmacodynamics 58 RT qPCR 58 Systemic Delivery 58 Pharmacokinetic PK 58 ChronVac C R 58 delafloxacin 58 microarray gene expression 58 radiation dosimetry 58 Annamycin 58 Protein Interactions 58 non nucleoside 58 HTS assay 58 epigenetic therapies 58 PRTX 58 chemoinformatics 58 preclinical toxicology 58 Omacetaxine 58 Affymetrix GeneChip ® 58 BAL# [002] 58 Syllego system 58 CDK inhibitor 58 Zysolin TM 58 Onconase 58 ChIP seq 58 chemometrics 58 experimentally validated 57 molecular biomarkers 57 siRNA duplexes 57 microRNA profiling 57 depsipeptide 57 oral prodrug 57 proteomic analyzes 57 Mass Spectrometry MS 57 DXL# 57 teriflunomide 57 peptide conjugated 57 liposomal formulation 57 Biomerk Tumorgrafts 57 #T# L1 57 antisense inhibitor 57 inhibitor RG# 57 manually curated 57 p# biomarker 57 DNA methyltransferases 57 Phase Ib study 57 PET tracer 57 pharmacogenetic testing 57 humanized anti 57 Pharmacokinetics 57 torezolid 57 Peptidomics 57 nucleic acid isolation 57 orally dosed 57 Technology LVT 57 predictive biomarkers 57 Xanafide 57 cationic lipid 57 DNA intercalator 57 transgenic mouse models 57 Kinase Inhibitor 57 metabolomic 57 vidofludimus 57 SmartChip TM Real 57 Pharmacokinetics PK 57 ICH guidelines 57 pharmacokinetic pharmacodynamic PK PD 57 transcriptional regulation 57 clinical 57 atherosclerosis regression 57 Multimeric 57 favorable pharmacokinetic 57 kinase profiling 57 heterologous expression 57 OMP #M# 57 IDO inhibitor 57 N glycan 57 Factor VIIa 57 antiapoptotic 57 CG# [003] 57 davunetide intranasal AL 57 HCV polymerase inhibitor 57 CYT# potent vascular disrupting 57 immunogenicity 57 GLP toxicology studies 57 pharmacophore 57 quantitative gene expression 57 CINQUIL 57 anti CD3 57 fosbretabulin 57 INT# [002] 57 predictive biomarker 57 PCR assays 57 biomarker assays 57 novel VDA molecule 57 TPI ASM8 57 AEG# 57 antitumoral 57 pharmacokinetic PK study 57 CDISC standards 57 genomic biomarkers 57 Affymetrix GeneChip 57 cytotoxicity assays 57 Activity Assay 57 XmAb# 57 CaPre TM 56 xenograft models 56 Phase Ib II 56 lyophilized formulation 56 JAK2 inhibitors 56 HCV protease 56 peptidomimetic 56 HybSelect 56 potency selectivity 56 Phenyx 56 Phase Ib clinical trials 56 Anticalin ® 56 Cloretazine R 56 Illumina Genome Analyzer 56 Annexin V 56 JAK2 inhibitor 56 histone acetyltransferase 56 tolerability pharmacokinetics 56 small molecule agonists 56 multivariate statistical 56 GRN#L 56 Quinamed 56 cyclophilin inhibitor 56 HTRF 56 preclinically 56 Combo Stent 56 ToleroMune 56 MEK inhibitors 56 metabolomic profiling 56 nonclinical studies 56 pharmacokinetics 56 Dataflow Manager 56 aCGH 56 vascular disrupting agents 56 recombinant antibodies 56 ZFN 56 isoform selective 56 MAQC 56 silico prediction 56 gamma secretase inhibitors 56 biostatistical analysis 56 JAK#/JAK# 56 nCounter Analysis System 56 mda 7 56 biomarker validation 56 NEUGENE 56 tubulin inhibitor 56 Pentad TM 56 DAVANAT 56 proteomics bioinformatics 56 IRX 2 56 CRLX# 56 TLR agonists 56 HCV protease inhibitors 56 Phase III Clinical Trials 56 cMET 56 viral kinetics 56 pan HDAC inhibitor 56 CCX# 56 THR beta agonist 56 immunotoxin 56 mutational analysis 56 humanized monoclonal 56 Sanger Sequencing 56 ADME PK 56 Pichia pastoris 56 recombinant polyclonal antibodies 56 Novolimus 56 Cyclosert TM 56 kinase assay 56 vivo validation 56 JAK inhibitors 56 UsiRNAs 56 TAFA# 56 Alfacell proprietary ribonuclease 56 Genedata Expressionist ® 56 JAK inhibitor 56 selective modulator 56 quantitative PCR qPCR 56 Cloretazine 56 R#/MEM 56 transcriptomics 56 bisulfite sequencing 56 nanoviricides 56 delipidation 56 ESBA# 56 X ray crystallographic 56 hepatoma 56 Trofex 56 comparative genomics 56 IMA# 56 Cytochrome P# 56 Anticalins ® 56 Preclinical studies suggest 56 pharmacokinetic parameters 56 pathophysiological effects 56 effector function 56 selective estrogen receptor modulator 56 CBLC# 56 vinca alkaloid 56 metabolomics 56 solithromycin 56 transcriptomic 56 immunohistochemical 56 IIa clinical 56 biomarker discovery 56 GAMMAGARD 56 biostatistical 56 metabonomics 56 protein ligand 56 Toxicogenomics 56 Chemophase 56 KL4 Surfactant 56 Locked Nucleic Acid LNA 56 automated microscopy 56 TOF TOF 56 quantitative trait loci 56 Microarray Analysis 56 heparanase 56 Drug Metabolism 56 Fc fusion protein 56 SynCon TM 56 Morpholino 55 vivo toxicology 55 nCounter 55 Fleximer 55 chemometric 55 BGC# 55 monoclonal antibody MAb 55 HDACi 55 VeraTag 55 Inhalation Solution 55 siRNA therapeutic 55 Pharmacodynamic 55 Guanilib 55 JVRS 55 bioinformatic tools 55 transcriptome analysis 55 MetaCore TM 55 GHRH 55 vitro experiments 55 Azedra 55 flow cytometric 55 evaluating tivozanib 55 CA9 SCAN 55 direct thrombin inhibitors 55 E WorkBook 55 Phase Forward InForm 55 prucalopride 55 antiproliferative activity 55 PD LID 55 oral proteasome inhibitor 55 Medidata Designer 55 Immunogenicity 55 Comparative Genomic Hybridization 55 #ME# 55 qRT PCR 55 Genotypic 55 Anticalin R 55 protein biomarker discovery 55 investigational humanized monoclonal antibody 55 ritonavir boosted 55 radiolabelled 55 Interferon alpha 55 synthetic siRNAs 55 PSN# [002] 55 IFN alpha 55 peptide synthesis 55 CCR5 antagonist 55 virus AAV 55 investigational HCV polymerase 55 miRNA biomarkers 55 Phase 1b trial 55 microsomal 55 microarray experiments 55 glycan structures 55 trodusquemine 55 Scaffold Based 55 replicon 55 APTIVUS 55 LSI #P 55 Anticalins R 55 MGd 55 pharmacokinetic profiles 55 Aspergillus nidulans 55 Dalbavancin 55 MetaCore 55 ALN TTR 55 LC MALDI 55 splice variants 55 PDX pralatrexate 55 biomodulator 55 Panzem R 55 Sequencing Systems 55 histone deacetylase HDAC inhibitor 55 dasatinib Sprycel 55 dose proportionality 55 Liposomal 55 IL #E 55 TKB# 55 Bioavailability 55 XOMA 3AB 55 delta isoform 55 acetylcholinesterase AChE 55 HCV replication 55 p# inhibitor 55 neuronal nicotinic receptor NNR 55 BACcel ™ system 55 enzyme immunoassay EIA 55 QPCR 55 GeneGo MetaCore 55 gene expression assays 55 HDL Mimetic Peptide 55 Pharmacogenomic 55 multiplexed assays 55 tolerability profiles 55 encapsulates siRNAs 55 RezularTM 55 Western Blotting 55 Phase 1a clinical 55 safety tolerability pharmacokinetic 55 genotyping gene expression 55 recombinant protein 55 A3 adenosine receptor 55 Initiated Phase 55 XmAb 55 biochemical profiling 55 poly ethylene glycol PEG 55 RNA Interference 55 Aurora Kinase 55 INCB# [001] 55 Elagolix 55 BrachySil TM 55 Preclinical Study 55 bevacizumab Avastin ® 55 NXL# 55 Triapine R 55 dopamine D2 55 phase IIa clinical 55 Provantis 55 Nanobody ® 55 kidney urologic 55 #S rRNA gene 55 Transcriptome 55 ART# 55 CHO K1 55 vivo RNAi 55 radiolabeling 55 PEGylated interferon 55 Immunotherapeutic 55 PEGylated 55 RE SURGE 55 Voreloxin 55 genotyping assays 55 small molecule activators 55 omics technologies 55 Sym# 55 phase Ib 55 BioMAP ® 55 subcutaneously administered 55 pharmacodynamics PD 55 eTag assays 55 Squalamine 55 stable nucleic acid 55 massively parallel sequencing 55 orally administered inhibitor 55 SNP arrays 55 Safinamide 55 5 hmC 55 Capsulution 55 DecisionSite 55 proprietary PEGylation 55 antimitotic 55 vitro pharmacology 55 recombinant antibody 55 XL# XL# 55 potent inhibitors 55 inferential statistics 55 Carfilzomib 55 ALN TTR# 55 Phase 1a 55 Valortim ® 55 PORxin 55 Chinese Hamster Ovary 55 proprietary LNA 55 Cyclosert 55 synDNA 55 druggable targets 55 selective adenosine 55 staphylococcal vaccine 55 CytoSure 55 p#/CBP 55 antisense inhibitors 55 DiLA 2 55 comparative genomic analysis 55 JAK2 V#F 55 Azedra TM 55 demonstrated antitumor activity 55 immunological responses 55 sulodexide 54 Axiogenesis 54 potently inhibit 54 Anavex #-# 54 RNA amplification 54 Exherin TM 54 targeting CD# 54 cynomolgus monkeys 54 Eg5 54 viral pathogenesis 54 PORxin TM platforms 54 multicenter Phase II 54 Infinium assay 54 EndoTAG TM 54 flavopiridol 54 peripherally acting 54 LAB CGRP 54 vivo efficacy 54 anti secretory 54 VDAs 54 MKC# MKC# PP 54 Panzem R NCD 54 Myocet 54 HuLuc# 54 protein ligand interactions 54 protein electrophoresis 54 synthetic peptides 54 Secretase 54 sd rxRNA 54 BiTE 54 maximally tolerated dose 54 tumorigenicity 54 potently inhibited 54 transcriptional profiling 54 RE LY ® 54 Transfection 54 Elvitegravir 54 NOX E# 54 Symadex 54 Refiner MS 54 immune modulating 54 clinical pharmacology studies 54 ZK EPO 54 synthetic siRNA 54 potent topoisomerase II 54 ganetespib 54 cariprazine 54 HIF PH inhibitors 54 affinity ligands 54 ON #.Na 54 GRNVAC1 54 OvaRex R 54 Small Molecule 54 Rosetta Elucidator 54 MChip 54 transfection efficiency 54 multiplex assays 54 therapeutic monoclonal antibodies 54 Fenretinide 54 SUTENT ® 54 PSMA ADC 54 ZFN modified 54 oral antiviral 54 Anticalins 54 multiplexing capability 54 bioinformatic 54 topically administered 54 NTDDS 54 FGFR4 54 RNAi Therapeutic 54 #beta estradiol 54 Next Generation Sequencing 54 Phase IIb III 54 Civacir 54 genomic profiling 54 skeletal sarcomere activators 54 GelSite R polymer 54 triphendiol 54 mimetics 54 Evoltra ® 54 CLORETAZINE TM VNP#M 54 Actilon 54 interactome 54 pharmacokinetic PK profile 54 anionic backbone 54 vivo potency 54 non nucleoside inhibitor 54 HGS# 54 AAV vectors 54 LC-MS/MS 54 Multiscale 54 RiVax 54 DepoVax TM 54 topically applied SEPA 54 gene expression profiling 54 entinostat 54 SmartChip System 54 HPAPIs 54 epitope mapping 54 quantitative PCR 54 Fragment Library 54 rEEG 54 beta actin 54 CellPort Technologies 54 RefSeq 54 Reports Preclinical Data 54 selective orally bioavailable 54 Vitalea 54 Zoraxel TM 54 receptor tyrosine kinase inhibitor 54 xCELLigence 54 Bevirimat 54 histone deacetylase HDAC 54 immunogens 54 xenograft 54 transgenic rats 54 Enhanze Technology 54 R#/MEM # 54 Imprime PGG 54 maturation inhibitor 54 trastuzumab DM1 T DM1 54 cheminformatics 54 pertuzumab 54 Genedata 54 CYT# 54 adipogenic 54 Histone Deacetylase 54 Curaxin 54 OncoVEX GM CSF 54 alpha7 54 ImQuest 54 potent antiproliferative 54 ActiveSight 54 Chemokine 54 Gene Expression 54 oral picoplatin 54 enzastaurin 54 GelSite polymer 54 DNA methylation biomarkers 54 gene loci 54 Bayesian methods 54 ZFNs 54 selective androgen receptor modulator 54 EOquin 54 Personalized Immunotherapy 54 antibody reagents 54 potent anti angiogenic 54 biased ligand 54 mGluR2 NAM 54 ImmuKnow R 54 mAb 54 genomics transcriptomics 54 Elucidator system 54 ELISA assays 54 Protein Kinase C 54 mAbs 54 tezampanel NGX# 54 ultrasensitive detection 54 ONCONASE R 54 PharmaPros 54 lipid nanoparticle 54 Microarray 54 multiplex assay 54 vitro assays 54 Quantitative PCR 54 cytoprotective 54 epoetin zeta 54 receptor inhibitor 54 bortezomib Velcade 54 Teriflunomide 54 Archexin 54 Janus Kinase 54 Glycosylation 54 LB# [003] 54 bioanalytical chemistry 54 bioimaging 54 antiangiogenic activity 54 protein biosynthesis 54 multiphoton microscopy 54 Reproducibility 54 Gag polymorphisms 54 somatostatin 54 nanopharmaceutical 54 adenoviral 54 gene expression microarray 54 biomarker assay 54 QTinno 54 inhalation toxicology 54 daptomycin 54 glutamate transporter 54 targeted radiotherapeutic 54 ospemifene 54 clevidipine 54 nucleoside tide 54 SNALP technology 54 lentiviral vector 54 lipidoid 54 Phase Ib 54 PARI Pharma 54 BRIM2 54 pharmacodynamic effects 54 IFN α 54 Pegasys ® 54 vitro assay 54 Phase Ib clinical 54 polyclonal antibody 54 GCP compliant 54 vivo assays 54 interleukin IL -# 54 Oral NKTR 54 de novo sequencing 54 immunodiagnostics 54 targeted antifolate 54 reverse transcriptase polymerase chain 54 polymerase inhibitors 54 Flt3 54 recombinant protein expression 54 Sapacitabine 54 HuMax EGFr 54 novel orally bioavailable 54 BCR ABL inhibitor 54 retaspimycin 54 HGS ETR2 54 non nucleoside HCV 54 Hematopoietic 54 QTL mapping 54 pharmacokinetic characteristics 54 mammalian proteins 54 HDAC Inhibitor 54 metabolomic profiles 54 IAP inhibitor 53 Genz # 53 annexin 53 proteomic analysis 53 Zybrestat 53 2D electrophoresis gels 53 liposomal delivery 53 SoftGenetics 53 anti CD# antibodies 53 phage display libraries 53 microsatellite markers 53 macrolide antibiotics 53 5 HT2A 53 antisense inhibition 53 multi analyte 53 OpenArray 53 nucleoside analog 53 hemagglutination inhibition HAI 53 chemogenomics 53 prognostic markers 53 CHO cell 53 lentiviral vectors 53 ALN PCS 53 tumor specific antigen 53 polymerase inhibitor 53 SpliceArray TM 53 selective kinase inhibitor 53 proteomics genomics 53 KL4 surfactant 53 Immunochemistry 53 protein purification 53 Prodarsan R 53 polyclonal 53 nasal decolonization 53 GastroPlus 53 Xenograft 53 DataLabsXC 53 relapsed MM 53 vitro studies 53 IL #p# 53 IAP inhibitors 53 microdroplet based 53 guanfacine extended release 53 siRNA knockdown 53 GLP compliant 53 biospecimen 53 Sphingomab 53 Illumina HiSeq 53 candidate TNFerade biologic 53 shRNA libraries 53 zinc finger nuclease 53 iTRAQ 53 analgesic efficacy 53 high throughput genotyping 53 erythropoietic 53 velafermin 53 linear pharmacokinetics 53 topoisomerase II inhibitor 53 endoglin 53 small molecule defensin 53 hematopoietic progenitor cells 53 ligand binding 53 HSP# inhibitors 53 vorinostat 53 AKT inhibitor 53 Oligonucleotide 53 TLR9 agonist 53 XP #L 53 multiplex PCR 53 HCV protease inhibitor 53 POTELLIGENT ® 53 adenoviral vectors 53 AVEO proprietary 53 CR# vcMMAE 53 Varespladib 53 physiologically relevant 53 IgG1 53 myoblast 53 microarray analysis 53 MDL Isentris 53 DermaVir 53 antibody MT# 53 compound AEZS 53 fluticasone furoate 53 lentiviral 53 NeuroSTAT ® 53 XTEN 53 LCP AtorFen 53 PEGPH# 53 Selexis 53 subunit vaccine 53 quantitative RT PCR 53 PIK3CA 53 Tarvacin TM 53 antitumor 53 PROSTASCINT R 53 anti infective treatments 53 glycosylated 53 chromatin immunoprecipitation 53 Presents Preclinical Data 53 pharmacogenetic 53 immunotherapeutic vaccine 53 intratumoral injection 53 DxC #i 53 CELVAPAN H#N# 53 IVIVC 53 apolipoproteins 53 microbial genomes 53 Array CGH 53 medicinal chemists 53 qNPA 53 NovaBay Aganocide compounds 53 bendamustine 53 Interferon beta 53 stem cell pluripotency 53 systemically administered 53 combinatorial libraries 53 humanized antibody 53 deforolimus 53 hematological tumors 53 Nautilus LIMS 53 excretion ADME 53 muscarinic receptor agonist 53 Hepatocytes 53 Protexia ® 53 mg kg BID 53 optimal dosing regimens 53 VelocImmune 53 Hedgehog inhibitor 53 Qdot 53 indibulin 53 micellar 53 ORENCIA R 53 immunochemistry 53 whole genome genotyping 53 mertansine 53 SNT MC# 53 rBChE 53 including eniluracil ADH 53 paclitaxel poliglumex 53 DIGE 53 radiolabeled 53 DB# [003] 53 accurate quantitation 53 synDNA TM 53 EDEMA3 trial 53 Pivotal Phase III 53 Mutation Analysis 53 ePRO solutions 53 YONDELIS 53 biocatalytic 53 posaconazole 53 cytokine refractory 53 Illumina genotyping 53 postoperative ileus POI 53 Affymetrix GeneChip R 53 subcellular localization 53 PPARgamma 53 Presents Preclinical 53 systemic RNAi therapeutic 53 molecular epidemiology 53 cystinosis patients 53 2 methoxyestradiol 53 diarrhea predominant irritable 53 inhibitor VX 53 CRMD# 53 telomerase activator 53 Molecular Diagnostic 53 PDE4 inhibitor 53 inhaled iloprost 53 LHRH antagonists 53 SCH # 53 transcriptome sequencing 53 M1 muscarinic 53 meganuclease 53 antiviral potency 53 immunotoxins 53 BioVant 53 molecularly targeted 53 EGFR HER2 53 PI3K/Akt pathway inhibitor 53 PXD# 53 matrix metalloproteases 53 orally inhaled migraine 53 molecular biomarker 53 CrossFire Beilstein 53 immunoregulatory 53 Prodarsan ® 53 QIAsymphony 53 Aganocide 53 Traficet EN 53 diagnostic biomarkers 53 cell lysate 53 FKBP# 53 HDA GT# TM 53 biodistribution studies 53 vapreotide acetate 53 NS5A 53 integrative genomics 53 2 inhibitor CYT# 53 HEK# cells 53 OncoVEX 53 efficacy tolerability 53 serine protease 53 BMS# 53 ELISAs 53 anti Parkinsonian 53 dextofisopam 53 DermaPrep 53 florbetaben 53 ceftazidime 53 PHX# 53 Trandolapril 53 antisense compounds 53 chromatin immunoprecipitation ChIP 53 gefitinib Iressa 53 mechanistic insights 53 Kinases 53 peripheral blood mononuclear 53 Posiphen 53 galectin 53 organogenesis 53 ANSYS Workbench platform 53 antineoplastic 53 Oral Insulin 53 murine mouse 53 virulence genes 53 Phase III Clinical Trial 53 Dasatinib 53 TSQ Vantage 53 post translational modifications 53 SMaRT ™ 53 selective antagonist 53 plasmid DNA vaccine 53 FOLFOX6 chemotherapy regimen 53 CanAg 53 Lixisenatide 53 ChIP Seq 53 BioFocus DPI Galapagos 53 transfection reagents 53 Initiates Clinical 53 protein tyrosine phosphatase 1B 53 alvespimycin 53 investigational pan BCR 53 tyrosine kinase inhibitor TKI 53 lymphoid tumors 53 ongoing Phase 1b 53 ArQule Kinase Inhibitor Platform 53 hMG 53 zonisamide SR 53 UML SysML 53 novel prodrug 53 Next Generation Sequencing NGS 53 miRNA assays 53 FVIIa 53 intravesical instillation 53 nucleoside nucleotide 53 S/GSK# 53 anticancer agent 53 neurotrophic factors 53 torezolid phosphate 53 AEGR 53 PEGylated interferon beta 1a 53 XmAb ™ 53 Pertuzumab 53 AZD# ARRY # 53 immunoregulation 53 CEQ# 53 RNA seq 53 acadesine 53 Zap CHO 53 PBMCs 53 tiapamil 53 bacterial genomes