Related by context. All words. (Click for frequent words.) 71 Allovectin 7 R 70 YONDELIS 70 FOLOTYN ® 69 pralatrexate 69 trastuzumab DM1 T DM1 69 Soliris TM eculizumab 69 OvaRex R 69 talactoferrin 69 TOCOSOL Paclitaxel 69 Virulizin R 69 Phase #b/#a clinical 69 OvaRex ® MAb 69 AMD# [003] 69 Zemiva TM 68 Phase Ib II 68 Amrubicin 68 Azedra 68 PEG SN# 68 FavId 68 maribavir 68 MyVax R 68 alvespimycin 68 PLK1 SNALP 68 WILEX 68 AEG# 68 OXi# 68 phase IIa clinical 68 OncoVEX 68 Solazed 68 ruxolitinib 68 CINTREDEKIN BESUDOTOX 67 Personalized Immunotherapy 67 Cloretazine ® 67 Trofex TM 67 Nexavar ® 67 Marqibo 67 phase IIb clinical 67 investigational therapies 67 Exherin TM 67 Myocet 67 Mozobil 67 CRMD# 67 Panzem R NCD 67 R sorafenib tablets 67 Cloretazine R 67 mertansine 67 EFAPROXYN 67 oral ridaforolimus 67 Insegia 67 Neo Urinary Conduit 67 refractory chronic lymphocytic 67 PRECISE trial 67 Cloretazine R VNP#M 67 forodesine 67 OPAXIO 67 Stedivaze 67 oral taxane 66 PrevOnco 66 PDX pralatrexate 66 L MTP PE 66 Evoltra ® 66 Solazed TM 66 Phase Ib study 66 Troxatyl 66 Allovectin 7 66 Civacir 66 IL# PE#QQR 66 PREOS R 66 TRISENOX 66 Icatibant 66 LEUKINE 66 Proxinium TM 66 Panzem 66 FOLOTYN 66 MAGE A3 ASCI 66 sapacitabine 66 INCB# [001] 66 Exelixis compounds 66 TELINTRA 66 LEP ETU 66 ELACYT 66 CA4P 66 registrational 66 HGS# 66 PrevOnco ™ 66 initiate Phase IIb 66 HGS ETR2 66 PXD# 66 drug ISA# 66 Chemophase 66 Azixa 66 Phase Ib clinical 66 AMD# [002] 66 StemEx R 66 neratinib 66 nonclinical studies 66 deforolimus 66 Phase #/#a trial 66 Allovectin 7 r 66 Cleviprex TM clevidipine 66 PNP inhibitor 65 Surfaxin LS 65 HGS ETR1 65 CD# CEA 65 OncoGel 65 THALOMID 65 vidofludimus 65 BrachySil TM 65 Azedra TM 65 Annamycin 65 AQ4N 65 Soliris eculizumab 65 including eniluracil ADH 65 Poly ICR 65 Archexin 65 EOquin TM 65 TOCOSOL Camptothecin 65 IMA# 65 SinuNase TM 65 Romidepsin 65 MGCD# [001] 65 BrachySil 65 cancer immunotherapies 65 SNT MC# 65 amrubicin 65 ularitide 65 sorafenib tablets 65 PANVAC VF 65 NEUMUNE 65 initiate Phase Ib 65 Phase IIIb clinical 65 Shigamabs ® 65 lintuzumab SGN 65 EndoTAG TM -1 65 custirsen 65 Phase IIb clinical trials 65 Panzem R 65 lucinactant 65 CoFactor 65 ORENCIA R 65 CCX# 65 CEQ# 65 StemEx 65 incyclinide 65 picoplatin 65 #D#C# 65 ZEVALIN ® 65 elotuzumab 65 entinostat 65 Cellegesic 65 Alzhemed TM 65 LEVADEX ™ 65 EOquin 65 tiapamil 65 assessing T DM1 65 Genasense ® 65 Dacogen injection 65 Shigamabs R 65 EP #R 65 candidate CRLX# 65 rhC1INH 65 BiovaxID TM 65 GRNVAC1 65 huC# DM4 65 Factor VIIa 65 L BLP# 65 CAMPATH 65 TRISENOX ® 65 G#DT 65 Onconase 64 PI3K/Akt pathway inhibitor 64 ganetespib 64 eTag assays 64 Combidex 64 BLA filing 64 TBC# 64 GRN#L 64 HuMax CD4 64 DR Cysteamine 64 oral picoplatin 64 GALNS 64 Tavocept 64 Genasense R 64 Fludara ® 64 LBH# 64 Urocidin 64 Fibrillex TM 64 Allovectin 7 ® 64 AeroLEF TM 64 Alocrest 64 YONDELIS R 64 dacetuzumab 64 TKM PLK1 64 initiate Phase 1b 64 Loramyc R 64 SUCCEED trial 64 MAA submission 64 IAP inhibitors 64 Targretin capsules 64 Androxal TM 64 LibiGel ® 64 oral deforolimus 64 Trofex 64 Cloretazine 64 IMiDs 64 Phase IIb III 64 omacetaxine mepesuccinate 64 DOS# 64 ALN VSP 64 RIGScan CR 64 TELCYTA 64 ProLindac 64 Velcade bortezomib 64 BioSTAR R 64 DPX Survivac 64 Vicinium TM 64 IMC #B 64 Virulizin ® 64 HspE7 64 GVAX R 64 GLP toxicology studies 64 ASH Annual Meeting 64 ALN TTR# 64 Initiate Clinical Trial 64 oral prodrug 64 bortezomib Velcade 64 PSMA ADC 64 vernakalant oral 64 bardoxolone 64 LungExpress Dx TM 64 Sym# 64 Phase III Pivotal 64 ALN PCS 64 OMP #M# 64 faropenem 64 ongoing Phase 1b 64 Canvaxin TM 64 Dyloject TM 64 zileuton CR 64 ApoB SNALP 64 SEPET TM 64 CYT# potent vascular disrupting 64 octreotide implant 64 Varespladib 64 Chrysalin 64 lintuzumab 64 Ceflatonin 64 ostarine 64 Veronate 64 successfully commercialize Iluvien 64 omega interferon 64 epigenetic therapies 64 clofarabine 64 ThermoDox R 64 GAP #B# 64 Telatinib 64 HuCAL antibodies 64 UPLYSO 64 acyclovir Lauriad R 64 histone deacetylase HDAC inhibitor 64 Ketotransdel 64 Phase Ib 64 Aphthasol R 64 novel VDA molecule 64 oncolytic virus therapies 64 ponatinib 64 OHR/AVR# 64 TYZEKA 64 MEPACT 63 Neo Kidney Augment 63 Vion Pharmaceuticals 63 CR# vcMMAE 63 tafamidis 63 TREANDA 63 HERmark 63 Targeted Chemotherapy 63 aflibercept 63 JAK1 63 OMS#HP 63 farletuzumab 63 ONTAK 63 enzastaurin 63 Xelox 63 sodium thiosulfate STS 63 Aurexis 63 sunitinib malate 63 torezolid phosphate 63 Daclizumab 63 Bendamustine 63 radiation sensitizer 63 Phase 1b trial 63 PROMACTA 63 MAXY G# 63 AzaSite Plus 63 Nanobody 63 RhuDex ® 63 rALLy trial 63 rNAPc2 63 ONCASPAR 63 Intravenous CP 63 R#/MEM # 63 tezampanel NGX# 63 ThermoDox ® clinical 63 anticancer compound 63 ITAX 63 AE# vaccine 63 ATryn R 63 ATG Fresenius S 63 Ixempra 63 Ceflatonin R 63 Phase 2b clinical 63 lumiliximab 63 XL# XL# 63 Hsp# Inhibitor 63 confirmatory Phase III 63 SinuNase ™ 63 TheraCIM 63 Omigard 63 Nexavar sorafenib 63 Stimuvax R 63 GRN# 63 Diabetic Macular Edema 63 trastuzumab DM1 63 IoGen 63 blinatumomab 63 Camvia 63 Generx ™ 63 Cintredekin Besudotox 63 Aflibercept 63 Phase #b/#a 63 Onco TCS 63 dextofisopam 63 telomerase inhibitor drug 63 Triapine R 63 Onko Sure TM 63 Hedgehog Pathway Inhibitor 63 Fabry Disease 63 ADVEXIN 63 eltrombopag 63 HepaSphere 63 Marqibo TM 63 Zavesca r 63 Ganite ® 63 rxRNA 63 Entereg TM 63 ANYARA 63 evaluating satraplatin 63 Multiferon R 63 Dalbavancin 63 midstage clinical 63 phase IIb 63 phase IIb III 63 vosaroxin 63 mapatumumab 63 VEGF Trap 63 Azedra ™ 63 axitinib 63 IV Busulfex 63 ASCO GI 63 tivozanib 63 HCD# [002] 63 Aplidin 63 Augment Injectable 63 leading oral taxane 63 oral proteasome inhibitor 63 pertuzumab 63 Elagolix 63 Amigal 63 Tamibarotene 63 omacetaxine 63 seliciclib CYC# 63 Azedra TM Onalta TM 63 Immunotherapeutic 63 Neulasta ® 63 Genentech Roche 63 isavuconazole 63 targeted radiotherapeutic 63 investigational monoclonal antibody 63 PROSTASCINT R 63 ospemifene 63 IRX 2 63 UVIDEM 63 volociximab 63 Aviptadil 63 ADVEXIN clinical 63 celgosivir 63 budesonide foam 63 evaluating tivozanib 63 Phase IIB 63 BrachySil ™ 63 Tarceva TM 63 MGd 63 HuLuc# 63 FACTIVE R gemifloxacin 63 Xanafide 63 Sulonex TM 63 ONCONASE 63 therapeutic monoclonal antibody 63 ® bortezomib 63 Marketing Authorization Application 63 Vandetanib 63 vernakalant iv 63 REOLYSIN ® 63 Zerenex ™ 63 Initiates Enrollment 63 adecatumumab MT# 63 BLA submission 63 Aryplase 62 oral methylnaltrexone 62 MEK inhibitors 62 ONCONASE R 62 doxorubicin Transdrug ® 62 Pivotal Phase III 62 interferon gamma 1b 62 phase III isavuconazole 62 GVAX ® 62 rALLy clinical trial 62 ZADAXIN ® 62 EXPAREL ™ 62 FOLFOX6 chemotherapy regimen 62 perifosine 62 Perifosine 62 PDE4 inhibitor 62 BEMA TM Fentanyl 62 bafetinib 62 randomized Phase 2b 62 Isolagen Process 62 Phase III Clinical Trial 62 VNP#M 62 Vaxfectin TM 62 Sopherion 62 Rescula 62 SCIB1 62 INTERCEPT platelets 62 Phenoptin 62 Phase 2b trial 62 JAK inhibitor 62 daclizumab 62 Eligard ® 62 phase IIb trial 62 SILENOR TM 62 OncoVEX GM CSF 62 adecatumumab 62 preclinical efficacy 62 Targretin 62 ixabepilone 62 HRPC 62 isoform selective 62 dexanabinol 62 Cimzia ® certolizumab pegol 62 ZEGERID Capsules 62 RECOTHROM R 62 Zemiva ™ 62 Octreotide 62 subcutaneous formulation 62 Nabi HB 62 Degarelix 62 StaphVAX R 62 AP# [003] 62 tezampanel 62 Celator 62 MEK Inhibitor 62 mitogen activated ERK kinase 62 JAK#/JAK# inhibitor CYT# 62 Cerashield 62 tramiprosate Alzhemed TM 62 candidate deforolimus 62 MYDICAR 62 Asentar 62 IND submission 62 investigational antiplatelet agent 62 Septin9 62 Modrenal R 62 Lenocta 62 Octreolin 62 obatoclax 62 AIMM trial 62 Xcytrin R 62 Aloxi injection 62 galiximab 62 Urocidin TM 62 Phase 1a clinical 62 Topical Interferon Alpha 2b 62 ZYBRESTAT 62 BAY #-# 62 GTC recombinant human 62 HepeX B TM 62 LE SN# 62 R vitespen 62 molecular imaging radiopharmaceutical 62 RAPTIVA R 62 CLIRS trial 62 Quinamed 62 Tarvacin TM 62 mifamurtide 62 Pralatrexate 62 XP# XP# 62 PROVENGE ® 62 thalidomide Thalomid 62 PHX# 62 CTCE 62 AzaSite Xtra 62 MYDICAR ® 62 IAP inhibitor 62 XL# anticancer compounds 62 ASONEP 62 Glufosfamide 62 IMGN# 62 Tesetaxel 62 ocular formulation 62 sumatriptan DosePro 62 CD# antibody [001] 62 HuMax TAC 62 refractory Hodgkin lymphoma 62 Phase 2a clinical trials 62 BCX# 62 Cx# [002] 62 VitiGam 62 histamine dihydrochloride 62 hoFH 62 Clolar ® 62 Nektar proprietary 62 Liprostin 62 bevacizumab Avastin ® 62 Phase III clinical 62 Embosphere Microspheres 62 systemic immunosuppressive drugs 62 docetaxel Taxotere ® 62 Increlex TM 62 telomerase therapeutic 62 Leukine 62 Oncotype DX colon cancer 62 SPRYCEL ® 62 TransVax TM 62 proteasome inhibitor 62 CBLC# 62 RGB # 62 Pivotal Phase 62 Clavis Pharma 62 Zenvia ™ 62 HQK 62 TransVax ™ 62 refractory PTCL 62 NPC 1C 62 Altastaph 62 NovaBay Aganocide compounds 62 fund BioSante LibiGel 62 BENLYSTA ® 62 Kamada AAT 62 acetonide FA 62 DXL# 62 BCR ABL inhibitor 62 Canvaxin 62 investigational pan BCR 62 Chemokine Therapeutics 62 histone deacetylase HDAC 62 tolevamer 62 CB2 selective receptor agonist 62 kidney urologic 62 Tykerb lapatinib 62 sapacitabine CYC# 62 HEPLISAV ™ 62 Panzem ® 62 Amoxicillin PULSYS Phase III 62 ongoing Phase IIIb 62 EGFR expressing mCRC 62 Specifid 62 LE DT 62 Announces Poster Presentations 62 Orathecin 62 OMNARIS HFA 62 ridaforolimus 62 SUPPRELIN LA 62 Metastatic Melanoma 62 Campath ® 62 relapsed multiple myeloma 62 Xcellerated T Cells 62 Fodosine 62 AMPK activators 62 BRIM2 62 Ceplene 62 rALLy 62 selective androgen receptor modulator 62 Zerenex 62 registrational trial 62 cetuximab Erbitux 62 dirucotide 62 Generx TM 62 AeroLEF R 62 tamibarotene 62 Litx 62 AGGRASTAT ® 62 glufosfamide 62 SYCREST 62 Anturol ® 62 VALSTAR TM 62 orBec 62 nalbuphine ER 62 Zybrestat 62 metastatic castration resistant 62 Phase IIa trials 62 BRAF inhibitor 62 trastuzumab Herceptin R 62 voreloxin 61 CTAP# Capsules 61 depsipeptide 61 Bioral Amphotericin B 61 Completes Patient Enrollment 61 pediatric acute lymphoblastic 61 BiTE R 61 Prestara TM 61 cintredekin besudotox 61 GEM OS2 61 Brentuximab Vedotin SGN 61 lorvotuzumab mertansine 61 Seliciclib 61 Reports Preclinical Data 61 tesetaxel 61 ENMD # 61 investigational immunotherapy 61 LHRH antagonist 61 CryoSeal 61 Pertuzumab 61 Protexia ® 61 Golimumab 61 Entereg R 61 metastatic castrate resistant 61 SinuNase 61 velafermin belinostat 61 FUSILEV ® 61 Raptiva ® 61 LymphoStat B TM 61 Pharmion Corporation 61 TRAIL receptor antibodies 61 Phase 1b clinical trials 61 CMV vaccine 61 Hepatocellular Carcinoma HCC 61 cellular immunotherapy 61 lomitapide 61 Squalamine 61 cetuximab Erbitux ® 61 BiTE antibody 61 CCR9 antagonist 61 Omacetaxine 61 rhThrombin 61 mocetinostat MGCD# 61 Glassia 61 Æterna Zentaris 61 BioNumerik 61 tubulin inhibitor 61 Onalta 61 GAMMAGARD 61 Neuromodulation System 61 Nipent R 61 TKM ApoB 61 opioid induced bowel dysfunction 61 zanolimumab 61 CYT# 61 Nektar pulmonary 61 QuadraSphere 61 Thalomid ® 61 Leukine ® 61 EVIZON TM squalamine lactate 61 alvimopan 61 investigational humanized monoclonal antibody 61 Ventavis 61 ADVEXIN p# therapy 61 Besivance 61 HepaGam B TM 61 Somatuline R Autogel R 61 Ocrelizumab 61 metastatic neuroendocrine tumors 61 SNALP technology 61 hematological malignancies 61 Increlex R 61 Phase 2a clinical 61 BST CarGel R 61 Gemzar ® 61 dacetuzumab SGN 61 DCVax R Brain 61 antibody MT# 61 generation purine nucleoside 61 AVE# 61 tremelimumab 61 Evoltra TM 61 Certican 61 TORISEL 61 EVIZON TM 61 Acute Radiation Syndrome ARS 61 SAR# [004] 61 dasatinib Sprycel 61 XL# XL# XL# XL# 61 BCR ABL inhibitors 61 Hyphanox 61 clevidipine 61 GATTEX TM 61 Phase 2a trial 61 Defibrotide 61 inhaled AAT 61 JAK inhibitors 61 Irinotecan 61 ZFP Therapeutics 61 Frova ® 61 HuCNS SC ® 61 personalized cellular immunotherapy 61 TRANSDUR Sufentanil 61 vorinostat 61 oncology indications 61 sipuleucel T 61 motexafin gadolinium Injection 61 prostone 61 dermatology biopharmaceutical company 61 Cinryze ™ 61 Firazyr ® 61 PRT# 61 EndoTAG TM 61 TNFerade 61 Selective Electrochemical Tumor Ablation 61 Onrigin TM 61 telaprevir VX 61 ALTROPANE 61 erlotinib Tarceva ® 61 romidepsin 61 DAVANAT R 61 Curaxin CBLC# 61 orally administered inhibitor 61 Microplasmin 61 radiotherapeutic 61 ATryn ® 61 lenalidomide Revlimid R 61 Advaxis Phase 61 Cethrin R 61 AdhTAP 61 HEPLISAV TM 61 Prestara 61 CD3 monoclonal antibody 61 CINOD 61 mSEPT9 61 Lauren Silvernail 61 Novolimus 61 recombinant factor VIIa 61 Tarmogen 61 INCB# [002] 61 perifosine KRX 61 sorafenib Nexavar 61 initiated Phase 1b 61 lymphoid malignancies 61 cangrelor 61 TLR8 agonist 61 2 inhibitor CYT# 61 Glybera 61 HER2 positive metastatic breast 61 Voraxaze 61 HDL Mimetic Peptide 61 TLR antagonists 61 nucleotide analog 61 StaphVAX 61 histone deacetylase inhibitor 61 cystinosis patients 61 MyVax ® 61 Cinryze TM 61 Ascend Therapeutics 61 Hexvix 61 Bicifadine 61 multiple myeloma MM 61 ZACTIMA 61 Neo Bladder Augment 61 LidoPAIN SP 61 Phase 1b 61 Exherin 61 polysaccharide polymer 61 ThermoDox ® 61 Lung Rx 61 SNS# T 61 HepaGam B 61 Solasia 61 Plenaxis R 61 ATL# [001] 61 oral beclomethasone dipropionate 61 docetaxel Taxotere R 61 P#X# antagonist 61 Uvidem 61 Removab 61 Manja Bouman CEO 61 Alvesco R 61 RH1 61 HuMax EGFr 61 IMC A# 61 HoFH 61 MyVax 61 sarcoma melanoma 61 Cimzia TM 61 TRO# 61 Zensana TM 61 vaccines oncolytic virus 61 OMNARIS Nasal Spray 61 fidaxomicin Phase 61 cannabinor 61 Urokinase 61 Granulocyte Colony Stimulating Factor 61 cediranib 61 DCVax ® Brain 61 Ultrafast Insulin 61 PROSTVAC TM 61 Vectibix panitumumab 61 NP2 Enkephalin 61 Vitaxin 61 Neo Kidney Augment ™ 61 Eligard R 61 Genasense ® oblimersen 61 Symadex 61 BioVant 61 tosedostat 61 Fludara 61 cMET 61 intravenous acetaminophen 61 TYSABRI natalizumab 61 multicenter Phase II 61 SANVAR 61 Clonicel 61 therapeutic monoclonal antibodies 61 Harry Palmin President 61 Imprime PGG 61 ALN TTR 61 catheter occlusion 61 KRN# 61 MEK inhibitor RDEA# 61 brostallicin 61 Evoltra 61 Gliadel Wafer 61 DCVax R 61 Vascular Wrap TM 61 pivotal bioequivalence 61 GED aPC 61 JAK2 inhibitor 61 tanespimycin 61 Tocosol Paclitaxel 61 Panzem NCD 61 HepeX B 61 Reolysin 61 riociguat 61 Phase III HEAT 61 Traficet EN 61 Phase IIb trials 61 OMAPRO 61 Augment TM 61 pivotal Phase III 61 candidate XP# 61 dextromethorphan quinidine 61 TLR9 agonist 61 Davanat 61 Zemplar Capsules 61 Phase III Clinical Trials 61 TAXUS TM 61 Inhalation Solution 61 Sular formulation 61 RECOTHROM ® 61 ALN RSV# 61 EGFR HER2 61 Genz # 61 PGL# 60 HDL Selective Delipidation 60 2 methoxyestradiol 60 coronary stent merged 60 Campath alemtuzumab 60 evaluating picoplatin 60 OVATURE 60 bazedoxifene 60 Junovan 60 Deforolimus 60 Zingo TM 60 OLEPTRO TM 60 Altropane 60 Vasovist 60 Rhucin ® recombinant 60 Zelrix 60 Combination REOLYSIN R 60 Initiate Phase 60 Phase Ib IIa 60 Rhucin ® 60 ORE# 60 midstage studies 60 Treanda 60 NXL# 60 Neuradiab 60 Teysuno 60 eniluracil 60 Estybon ™ 60 PRESEPT 60 ANTEGREN 60 NEBIDO R 60 aerosolized KL4 surfactant 60 Tectin TM 60 NEUVENGE 60 severe hypercholesterolemia 60 OncoVex 60 Neupogen ® 60 Alnylam #x# 60 candidate TNFerade biologic 60 Toraymyxin TM 60 Thelin TM 60 Viramidine 60 Tovaxin ® 60 rThrombin 60 Anavex #-# 60 Phase IIB clinical 60 refractory cutaneous T 60 teduglutide 60 induced macular edema 60 iii Cubist 60 metastatic pancreatic 60 atacicept 60 DXL TM 60 Phase IIa clinical trials 60 EndoTAG 60 SIR Spheres 60 Pirfenidone 60 MCSP respectively 60 NEBIDO 60 immatics 60 Curaxin 60 IMiDs ® compound 60 AzaSite TM 60 NEUGENE 60 Iluvien ® 60 RAV# 60 Proellex TM 60 BHT DNA 60 fidaxomicin Phase 3 60 DIFICID ™ 60 Plenaxis TM 60 preclinical toxicology 60 Tracleer R 60 hematological cancers 60 IgG1 monoclonal antibody 60 Phase 2b study 60 LUNESTA TM 60 Oncoscience AG 60 MYLOTARG 60 rindopepimut 60 Catena ® 60 Anturol 60 HCV protease inhibitor 60 AVAX 60 HuMax 60 EGS# 60 PS# [001] 60 DAVANAT ® 60 Chronic Lymphocytic Leukemia CLL 60 Phase III Trial 60 Ophena 60 Vascular Wrap 60 Ambrisentan 60 drug GAP #B# 60 Diamyd ® 60 generation Hsp# inhibitor 60 NeuroVax TM 60 Oracea TM 60 elacytarabine 60 relapsed leukemia 60 initiated Phase Ib 60 fibrin sealant 60 please visit www.advaxis.com 60 Nasdaq PPHM 60 Satraplatin 60 inhaled treprostinil 60 Opexa 60 antibody MAb 60 Alferon N 60 Nanobody R 60 Achieves Primary Endpoint 60 Tezampanel 60 generation rotary VAD 60 L DOS# 60 PREOS 60 OMP #R# 60 Initiates Phase II 60 Kuvan TM sapropterin 60 investigational compounds 60 ionotropic glutamate receptor antagonists 60 Hybridon 60 VitiGam TM 60 dose escalation clinical 60 Phase IIb clinical 60 Tramiprosate ALZHEMED TM 60 bosutinib 60 selective immunoproteasome inhibitor 60 preclinical 60 LEVADEX TM 60 Therapeutic Vaccine 60 biosurgical 60 Prodarsan ® 60 voclosporin 60 Phase 2b Clinical Trial 60 metastatic hormone refractory 60 VALSTAR 60 Ferumoxytol 60 RNAi therapeutic targeting 60 balsalazide tablet