Related by context. All words. (Click for frequent words.) 73 Phosphorylation 72 Inhibits 70 Inhibiting 70 Macrophage 68 Induces 68 extracellular signal 68 Transcriptional 67 phosphatidylinositol 3 67 Factor Receptor 67 Inhibitors 67 Protein Kinase 67 Intracellular 66 FasL 66 inhibition 66 induces apoptosis 66 Upregulation 66 mitogen activated protein kinase 66 Inhibitor 66 Modulates 65 Epithelial 65 microglial activation 65 Apoptosis 65 Inactivation 65 ERK1 2 65 Proteasome 65 Cytotoxic T 65 selective inhibition 65 Anti Tumor 65 Androgen Receptor 65 proteolysis 65 c MYC 64 downregulation 64 induced apoptosis 64 Receptor Antagonist 64 Oncogenic 64 Tumor Necrosis Factor 64 TGF ß 64 downregulates 64 Endothelial 64 Endothelial Cells 64 HIF 1alpha 64 Cell Adhesion 64 autophagic 64 PDGFR 64 MEK1 64 Synthase 63 mediated apoptosis 63 Attenuates 63 mitogenic 63 Dendritic Cells 63 Extracellular 63 AT1R 63 Angiotensin II 63 Hedgehog signaling 63 inducible 63 eNOS 63 tyrosine phosphorylation 63 Transcription Factor 63 Overexpression 63 LPS induced 63 Anti Tumor Activity 63 Signaling Pathway 63 siRNA mediated 63 Cyclooxygenase 2 63 Rho kinase 63 Protein Kinase C 63 TNFalpha 63 proapoptotic 63 upregulation 63 Calcineurin 63 MAP kinase 63 Immune Responses 63 pRb 63 activin 62 HepG2 cells 62 MAPK 62 Rap1 62 Reductase 62 Kinase Inhibitor 62 TGF b 62 tubulin polymerization 62 Receptor Antagonists 62 Interferon gamma 62 IL 1β 62 nitric oxide synthase 62 RANK Ligand 62 S1P 62 inhibitory effects 62 Mouse Model 62 lysosomal 62 GLI1 62 ligand TRAIL 62 androgen receptor AR 62 Clusterin 62 Transgenic Mice 62 Androgen 62 related apoptosis inducing 62 uPAR 62 Histone 62 IFN gamma 62 Factor VEGF 62 iNOS 62 triggers apoptosis 62 intracellular signaling 62 Orally Active 62 E#F# 62 adhesion molecule 62 MEK ERK 62 β catenin 62 Epidermal Growth Factor Receptor 62 mediated inhibition 62 selectively inhibited 62 p# mitogen activated 62 IGF 1R 62 Kinases 62 Neutrophil 62 glutamate receptors 62 HIF 1α 62 serine threonine kinase 62 Dehydrogenase 62 Microtubule 62 Antagonists 62 Homeostasis 62 Oxidative 62 tubulin 62 overexpressing 62 glucocorticoid receptor 61 EGF receptor 61 Oncolytic Reovirus 61 VEGF receptor 61 proto oncogene 61 Induces Apoptosis 61 nicotinic acetylcholine receptor 61 Tyrosine Kinase Inhibitor 61 Nampt 61 Antigen Specific 61 Akt activation 61 Aurora Kinase 61 MMP2 61 Potent Inhibitor 61 lymphotoxin 61 induce apoptosis 61 downstream effector 61 decarboxylase 61 Novel Mechanism 61 Reactive Oxygen Species 61 Cancer Cells 61 prostaglandin synthesis 61 cyclooxygenase 2 61 P selectin 61 Polymorphisms 61 Angiogenic 61 adrenoceptor 61 Suppresses 61 Novel Inhibitor 61 PTP 1B 61 Neuronal 61 Mutational 61 ERK signaling 61 receptor tyrosine kinase 61 PKC isoforms 61 ectopic expression 61 Mucosal 61 Stromal 61 Tumor Suppressor 61 alpha GAL 61 neurite outgrowth 61 Neuroprotection 61 aberrantly activated 61 catenin 61 Oxidase 61 hypoxia inducible factor 61 Tie2 61 Receptor Agonist 61 neuropeptide Y 61 selectively inhibits 61 Kinase 61 Signaling Pathways 61 LNCaP cells 61 ubiquitin ligase 61 Dopaminergic 61 Catenin 61 HDAC enzymes 61 protein kinase C 61 NF kappaB activation 60 apoptotic 60 Liposomal 60 Kinase Inhibitors 60 Small Molecule 60 Angiotensin 60 matrix metalloproteases 60 E selectin 60 ubiquitination 60 antiproliferative activity 60 Therapeutic Potential 60 p# MAPK 60 Recombinant Human 60 PC# cells 60 HIF 1a 60 ATPase 60 Progenitor Cells 60 antiapoptotic 60 Tubulin 60 poly ADP ribose polymerase 60 Tumor Growth 60 deacetylation 60 pro angiogenic 60 NKT cell 60 E3 ligase 60 p# alpha [001] 60 potent inhibitor 60 phosphorylates 60 Platelet Derived Growth 60 Selective Inhibitor 60 tyrosine kinase receptor 60 Inducible 60 Beta Amyloid 60 cyclooxygenase 60 mTOR 60 cytosolic 60 acetylcholine receptor 60 Inhibitory 60 Inhibit 60 ß catenin 60 elastase 60 pharmacological inhibition 60 Skeletal Muscle 60 UCP2 60 PI3 kinase 60 Nitric Oxide Synthase 60 Controlled Trial 60 mediated phosphorylation 60 TNF Alpha 60 phosphate S1P 60 pathophysiological effects 60 Antitumor 60 Targeted Therapy 60 Rac1 60 ERK phosphorylation 60 nitric oxide synthase NOS 60 SIRT2 60 Leukocyte 60 Caveolin 1 60 Syk 60 TGF beta1 60 IL 1ß 60 transactivation 60 Antiangiogenic 60 regulated kinase ERK 60 Smoothened 60 Cytochrome P# 60 Histone Deacetylase 60 Aptamer 60 TNF α 60 Integrin 60 Protein Synthesis 60 Hepatocyte 60 1beta 60 Endothelin 60 Oxidative Stress 60 superoxide dismutase 60 myeloid derived 60 regulated kinase 60 c MET 60 PGE2 60 heme oxygenase 1 60 Dysregulation 60 Akt 60 osteoclast formation 60 p# MAP kinase 60 Oligonucleotide 60 1alpha 60 Preclinical Study 60 Tumor necrosis factor 60 constitutively expressed 60 Enzastaurin 60 overactivation 60 phosphatases 59 Allosteric 59 antitumor 59 Prolactin 59 phagocytosis 59 PI3K Akt 59 cell adhesion molecule 59 p#Kip# 59 endothelial nitric oxide synthase 59 HCV protease 59 PPARgamma 59 Î ² 59 Aβ 59 Novel Oral 59 interferon γ 59 potentiates 59 Secretory 59 Immunomodulatory 59 transcriptional activation 59 Smad3 59 Hypoxia Inducible Factor 59 secretase 59 chemokine receptor 59 cAMP 59 humoral 59 cell mediated cytotoxicity 59 Cytokines 59 Glucocorticoid 59 RNA Interference 59 Janus kinase 59 Rho GTPase 59 Chemotherapeutic Agents 59 potent inducer 59 TLR2 59 Differentially 59 Mimetics 59 survivin 59 Superoxide 59 Allogeneic 59 intracellular 59 Chemokine Receptor 59 NF kappaB 59 receptor mediated 59 Antitumor Activity 59 miR #a [001] 59 inducible nitric oxide synthase 59 SGLT2 59 Adenosine 59 cytoplasmic domain 59 Cytotoxicity 59 Ras MAPK pathway 59 Disease Progression 59 N cadherin 59 glycosyltransferase 59 Activating mutations 59 protein tyrosine phosphatase 1B 59 Tyrosine Kinase 59 Aldosterone 59 NF KappaB 59 upregulate 59 prostaglandin E2 PGE2 59 pro apoptotic 59 Autoantibodies 59 cytokine 59 murine 59 converting enzyme 59 VEGFR2 59 upregulating 59 GTPase 59 vascular endothelial 59 Analogs 59 Jhdm2a 59 protein CETP 59 Polymorphism 59 vimentin 59 prostaglandin E 59 selective antagonist 59 cystic fibrosis transmembrane conductance 59 Rab5 59 acyltransferase 59 NF κB 59 homodimers 59 oxidase 59 oligomerization 59 IL 1beta 59 monocytes macrophages 59 1α 59 glucose transporter 59 PDE4 59 Kv#.# 59 Apoptotic 59 Antisense Oligonucleotides 59 Axonal 59 paracrine 59 5 HT1A 59 overexpression 59 serine threonine 59 demethylation 59 Vascular Endothelial Growth 59 TGF β 59 Selective inhibition 59 caveolin 1 59 synthetase 59 caveolin 59 potent inhibition 59 RANK ligand 59 EGFR signaling 59 tumor suppressor 59 EZH2 59 muscarinic receptors 59 PI3K/Akt 59 Caspase 59 pDC 59 Eg5 59 arginase 59 JAK STAT 59 Mcl 1 59 PI3K pathway 59 FKBP# 59 cytokines IL 59 Nedd4 59 Modulating 59 factor HGF 59 CEACAM1 59 NKG2D 59 eIF4E 59 Preclinical Data 59 mTOR signaling 59 induced cytotoxicity 59 STAT3 59 neurturin 59 dopamine reuptake 59 Pharmacodynamics 59 cathepsin B 59 immunostimulatory 59 MAPK pathway 59 thioredoxin 58 Mesenchymal Stem Cells 58 immunoreactivity 58 tumor vasculature 58 chemoattractant 58 protein kinases 58 upregulates 58 adrenergic receptor 58 signaling pathway 58 JAK2 enzyme 58 cyclin dependent kinases CDKs 58 Mammalian 58 metalloproteases 58 neurotrophic 58 NF kB 58 AMPA receptor 58 1ß 58 Epithelial Cell 58 Glutamate 58 TNFα 58 selective modulator 58 reductase 58 Tumor Cell 58 PLA2 58 cyclin D1 58 serine protease 58 acyl CoA 58 serotonin reuptake 58 cyclooxygenase COX 58 mRNA expression 58 vascular permeability 58 Polymerase 58 Osteopontin 58 RUNX3 58 BACE1 58 frataxin 58 cyclin dependent kinase 58 Present Preclinical Data 58 N methyl 58 Novel Small Molecule 58 muscarinic 58 ubiquitylation 58 Adiponectin 58 PKC inhibitor 58 Incretin 58 c Src 58 TGF beta signaling 58 Immunohistochemical analysis 58 neurotrophic factor 58 protein kinase 58 TGFß 58 alpha subunit 58 kinase pathway 58 TrkA 58 TGF beta 58 receptor subtypes 58 Protease 58 Monocytes 58 Protein Interactions 58 dose dependently 58 phosphoinositide 3 58 PPARg 58 TRAIL R2 58 EGFr 58 TRAIL induced apoptosis 58 adenylate cyclase 58 cyclins 58 NADPH oxidase 58 GSK 3ß 58 prolyl 58 reversible inhibitor 58 5 lipoxygenase 58 Cerebrospinal Fluid 58 anti CD3 58 costimulatory 58 tyrosine kinase 58 S#P# 58 osteoclast activity 58 receptor subtype 58 Receptor 58 Gene Mutation 58 glucagon receptor 58 Clinical Outcome 58 cytotoxicity 58 Hsp# chaperone 58 cyclin dependent kinase inhibitor 58 hepatoma 58 mice lacking 58 lipoxygenase 58 PAR1 58 chemoresistance 58 FUS1 58 CXCL# 58 Cyclin E 58 peroxisome proliferator activated 58 IGFBP2 58 Gene Silencing 58 receptor antagonism 58 Breast Cancer Cells 58 oncoprotein 58 Neuroprotective 58 transmembrane protein 58 NMDA receptors 58 E3 ubiquitin ligase 58 MT1 MMP 58 lymphangiogenesis 58 Conformational 58 small molecule inhibitor 58 Fibroblast 58 Hypertensive Patients 58 Meta Analysis 58 Systemic Delivery 58 ERK pathway 58 Fibrinogen 58 inhibitory 58 GSK3B 58 Vascular endothelial growth 58 Well Tolerated 58 Secretion 58 Preclinical studies suggest 58 estrogen receptor alpha 58 pro inflammatory cytokine 58 exocytosis 58 Th# 58 Prostate Cancer Progression 58 Alu RNA 58 fosbretabulin 58 Heme 58 NQO1 58 methyl D aspartate 58 Tumor Angiogenesis 58 annexin V 58 CCL2 58 Cannabinoid 58 transthyretin 58 HDAC 58 Survivin 58 Anti Angiogenic 58 LDL receptor 58 matrix metalloproteinases 58 Receptor Agonists 58 Denufosol 58 β cells 58 STAT1 58 Flt3 58 TLR9 58 apoptotic pathway 58 Carcinomas 58 cytotoxic T lymphocyte 58 transduced 58 P glycoprotein 58 Modulators 58 transcriptional repression 58 VEGF induced 58 Glycoprotein 58 Hematopoietic Stem Cells 58 monocyte chemotactic protein 58 VE cadherin 58 mRNA 58 ERK activation 58 androgen receptor 58 mRNA translation 58 Therapeutic Effects 58 TGFβ 58 GTPases 58 Neurotransmitter 58 #HT#A 58 inflammatory cytokines 58 phosphatidylinositol 58 hydrolase 58 Src 58 raphe 58 Brain Derived Neurotrophic 58 Prolongs Survival 58 Novel Therapeutic 57 noradrenergic 57 sphingosine 1 57 HDAC6 57 potent inhibitors 57 Autologous Stem Cell Transplantation 57 platelet activation 57 upregulated 57 cells transfected 57 effector function 57 synuclein 57 vWF 57 syntaxin 57 Myeloid 57 small molecule inhibitors 57 CCR2 57 lipopolysaccharide 57 heme oxygenase 57 Dendritic Cell 57 RANKL 57 Mitochondrial 57 cell motility 57 gamma secretase 57 Breast Cancer Metastasis 57 irreversible inhibitor 57 Extracellular Matrix 57 IFN γ 57 Wnt 57 agonist induced 57 mu opioid receptor antagonist 57 enzymatic activity 57 nNOS 57 Gene Variants 57 NFkB 57 NF kB activation 57 Regulates 57 ErbB3 57 Methylation 57 Hh 57 telomerase reverse transcriptase 57 adipogenic 57 P2X 57 VEGF 57 phagocyte 57 DNA intercalator 57 NKX#.# 57 Smooth Muscle 57 TGF Beta 57 protein tyrosine kinase 57 Retinoic Acid 57 Germline 57 cytoprotective 57 Smad 57 c myc 57 Monocyte 57 apoptosis pathways 57 Cdc# 57 metalloprotease 57 Vidofludimus 57 Bortezomib 57 TGF ß1 57 receptor activation 57 Kinesin 57 microglial 57 CCR1 57 NS5A 57 receptor kinase 57 Neuroprotective Effects 57 PI3K 57 Biosynthesis 57 CTGF 57 constitutively active 57 hepatic glucose production 57 Neurotrophic Factor 57 NAD + 57 neutrophil infiltration 57 CDKs 57 endocytosis 57 SMN1 57 Placebo Controlled Trial 57 Binding Protein 57 Induced 57 Dystrophin 57 anti apoptotic 57 selectively inhibit 57 lysophosphatidic acid 57 thymidylate synthase TS 57 NFAT 57 adrenocortical 57 tumorigenesis 57 vascular endothelial cells 57 beta catenin 57 Secretase 57 kinase PI3K 57 Dose Response 57 Renin 57 p# [001] 57 COX2 57 angiotensin II receptor 57 bFGF 57 histone deacetylases 57 enkephalin 57 thyroid hormone receptor 57 Antagonist 57 5 HT2A receptor 57 Lymphocyte 57 transgene expression 57 Ubiquitin 57 Endothelium 57 P#Y# [002] 57 hTERT 57 c Myc 57 Muscarinic 57 highly selective inhibitor 57 MDM2 57 Impairs 57 astrocytic 57 Cell Differentiation 57 PP2A 57 dystroglycan 57 LPA1 receptor 57 Aurora kinase 57 Mediated 57 phosphorylation 57 PI3 Kinase 57 5 HT6 receptor 57 acetyltransferase 57 Cyclooxygenase 57 SCD1 57 Neurogenesis 57 adenosine receptor 57 serine proteases 57 Cx# [001] 57 monocyte 57 Low Dose 57 receptor alpha 57 Skp2 57 Neuropeptide Y 57 TNF receptors 57 5 HT4 receptor 57 Raf kinase 57 BMP signaling 57 estrogen receptor beta 57 Receptor Signaling 57 proinflammatory cytokines 57 GAPDH 57 CK2 57 Phosphatase 57 ERalpha 57 F actin 57 TSP1 57 CD1d 57 HGF 57 Bcl XL 57 ornithine decarboxylase 57 Tumor Targeting 57 paxillin 57 antisense oligonucleotide 57 caspase activation 57 oncogenic signaling 57 CD# CD# 57 Adjuvant Chemotherapy 57 phosphatase 57 mGluR 57 Cathepsin B 57 phospholipase A2 57 LRP6 57 IL #E 57 fatty acid oxidation 57 HDAC2 57 histone deacetylase 57 potently inhibit 57 TIMP 1 57 Aß 57 TORC2 57 Fas ligand 57 neuroprotection 57 Interferon Beta 57 P2Y 57 caspases 57 autocrine 57 EphA2 57 HCV replication 57 generation antisense inhibitor 57 Runx2 57 Radiofrequency Ablation 57 Th1 type 57 ABCA1 57 transcriptional repressor 57 Mouse Models 57 cotransporter 57 PPAR gamma 57 antibody mediated 57 Wnt signaling 57 endonuclease 57 CD#L 57 protein secreted 57 FGF receptor 57 Antithrombin 57 cyclic adenosine monophosphate cAMP 57 HER3 57 Molecular Mechanism 57 proximal tubule 57 oncogenic 57 PDGF receptor 57 P#Y# [001] 57 GPR# [002] 57 Oligomers 57 Nrf2 57 Th# cells 57 bradykinin 57 CD8 + 57 TGF β1 57 pleiotropic 56 tumor angiogenesis 56 Neural Stem Cells 56 mTOR mammalian target 56 integrin alpha 56 constitutively 56 ErbB2 56 plasmin 56 partial agonist 56 TNFa 56 Transdermal Delivery 56 beta amyloid peptide 56 Pharmacologic 56 presynaptic 56 Insulin Resistance 56 Hsp# [002] 56 TNF alpha 56 aldose reductase 56 Cdc7 56 utrophin 56 FGFR4 56 secretion 56 TGF alpha 56 NR2B subunit 56 Adenoviral 56 dimerization 56 FOXO 56 thrombospondin 56 Akt signaling 56 hedgehog pathway 56 synapse formation 56 Glial 56 Ischemic 56 catecholamine 56 nicotinamide 56 ,#,# [002] 56 adipocyte 56 Cytoplasmic 56 Nerve Growth 56 p#NTR 56 Transmembrane 56 Estrogen Receptor 56 p# activation 56 Wnt beta catenin 56 cAMP signaling 56 IL #R 56 oxidative phosphorylation 56 Mitotic 56 alpha Gal 56 receptor antagonists 56 excitotoxic 56 CYP#A# CYP#D# 56 Ad5FGF 4 56 neuronal dysfunction 56 selectively inhibiting 56 H#K# [002] 56 anti apoptotic proteins 56 receptor agonists 56 erythropoietin receptor 56 receptor partial agonist 56 intratumoral injection 56 Angiotensin converting enzyme 56 HSP# 56 WT1 56 Drug Candidate 56 Cell Proliferation 56 c Fos 56 microsomal 56 Drp1 56 receptor signaling 56 caspase 56 retinoic acid receptor 56 glucocorticoid 56 CCR3 56 PDGFR alpha 56 enzyme inhibitors 56 Metabolites 56 polyamine 56 Sp1 56 ACE2 56 type glutamate receptor 56 Bcl 2 56 lymphocyte 56 Genes Involved 56 HDAC inhibition 56 4E BP1 56 receptor gamma 56 LTB4 56 Monotherapy 56 targetters 56 fibrin deposition 56 homodimer 56 HGF c Met 56 NFkappaB 56 Statistically Significant 56 peroxidase 56 Improves Survival 56 CDK inhibitor 56 phosphoinositide 56 induced phosphorylation 56 BCL2 56 phospho 56 peptidase 56 glycogen synthase kinase 56 calpain 56 Tumor Cells 56 Senescence 56 ischemia reperfusion injury 56 Epitopes 56 Brain derived neurotrophic 56 cytochrome c 56 Hsp# chaperone system 56 eIF2 56 Therapeutic Targets 56 humoral immunity 56 Nuclear Receptor 56 γ secretase 56 HIF1 56 synthase 56 Androgen receptor 56 5' monophosphate 56 Abl 56 angiotensin II 56 VEGF pathway 56 NF kappa B 56 Synuclein 56 Breast Tumors 56 beta subunit 56 PTP1B 56 MAPK signaling pathway 56 hepatocyte growth 56 TGF beta pathway 56 glucokinase 56 chemokine receptors 56 amyloid β 56 pro inflammatory cytokines 56 cholecystokinin CCK 56 inhibits protein synthesis 56 XIAP 56 CTLs 56 inverse agonist 56 cytokine signaling 56 protein encoded 56 glioma cells 56 Growth Factor Receptor 56 D aspartate 56 Cytotoxic 56 topoisomerase II 56 PDE1 56 MAP kinase pathway 56 Peripheral Blood 56 antisense inhibition 56 Transcriptome 56 VEGF expression 56 Fibroblast Growth Factor 56 HepG2 56 IGF1R 56 PEGylated Fab fragment 56 thromboxane A2 56 Subunit 56 ERa 56 vasoactive 56 tumor antigen 56 small molecule tyrosine 56 PDGFR B 56 myocyte enhancer factor 56 Treating Chronic 56 Nucleic Acids 56 acetylcholinesterase 56 Lymphocytes 56 Hematopoietic 56 IGF IR 56 mitotic kinesin 56 fibrogenesis 56 ERK 56 osteoblast differentiation 56 transcriptional regulation 56 Epitope 56 tropomyosin 56 MyD# 56 thymic 56 soluble tumor necrosis 56 5 hydroxytryptamine 56 erythropoiesis 56 CatB 56 NO synthase 56 Th2 cytokines 56 amyloid peptide 56 MUC1 56 ENaC 56 metalloproteinase 56 Endogenous 56 HIF1 alpha 56 β2 56 M1 muscarinic 56 intercellular adhesion molecule 56 factor receptor FGFR 56 Antisense 56 Aberrant