Related by context. All words. (Click for frequent words.) 65 DSM IV 65 DSM IV diagnosis 63 prespecified criteria 62 DSM IV TR 60 Structured Clinical 59 Mental Disorders Fourth 59 schizophrenia schizoaffective disorder 59 Mental Disorders IV 59 syndromal 59 predefined criteria 58 comorbid 58 DSM IV diagnostic 58 schizophreniform disorder 57 secondary efficacy endpoints 57 nonpsychotic 56 efficacy endpoint 56 psychiatric comorbidity 56 affective disorders 56 DSM IV Axis 56 affective disorder 56 psychiatric diagnoses 56 dysthymia 55 affective psychosis 55 subsyndromal 55 symptom severity 55 Major Depressive Disorder 55 MMSE score 55 Diagnostic Statistical Manual 55 DSM IV diagnoses 54 univariate analyzes 54 BPRS 54 subthreshold 54 unipolar depression 54 HAM D# 54 multivariate analyzes 54 subscales 54 primary efficacy endpoints 53 somatoform disorders 53 Mental Disorders DSM IV 53 primary efficacy endpoint 53 euthymic 53 logistic regression models 53 criteria 53 prevalences 53 Brief Psychiatric 53 covariate 53 prospectively defined 53 hyperkinetic disorder 53 euthymic patients 53 comorbid depression 53 comorbid diagnoses 53 logistic regression model 53 comorbidity 53 NCEP ATP III 53 sociodemographic characteristics 53 non affective psychosis 53 HAMD 53 probands 53 avoidant personality disorder 52 antisocial personality 52 posttreatment 52 psychotic disorders 52 psychoeducation 52 somatization disorder 52 hypomania 52 symptomatology 52 Montgomery Åsberg Depression 52 bulimia nervosa 52 primary endpoints 52 major depressive disorder 52 overnight polysomnography 52 Antisocial Personality Disorder 52 psychiatric morbidity 52 Solid Tumours 52 sd = 52 sociodemographic variables 52 noninferiority 51 psychotic symptoms 51 semistructured interview 51 sensory gating 51 Depressive symptoms 51 conditional logistic regression 51 desvenlafaxine succinate 51 subscale scores 51 covariates 51 dysthymic disorder 51 Research Diagnostic Criteria 51 MADRS score 51 subscores 51 postintervention 51 efficacy endpoints 51 somatoform disorder 51 psychiatric comorbidities 51 EDSS score 51 premorbid 51 PREZISTA r arm 51 hypersomnia 51 hypomanic symptoms 51 depressive symptomatology 51 Response Evaluation Criteria 50 Neuropsychiatric Inventory NPI 50 psychosocial functioning 50 Index CDAI 50 hypochondriasis 50 Hamilton Rating Scale 50 RECIST criteria 50 PANSS scores 50 psychometric properties 50 nonpsychiatric 50 comorbid psychiatric 50 #q# deletion syndrome 50 statistical significance p 50 virological response 50 somatic complaints 50 depressive symptoms 50 odds ratios ORs 50 % CI #.#-#.# [006] 50 QoL 50 Generalized Anxiety Disorder 50 venlafaxine XR 50 internalizing behaviors 50 psychiatric outpatients 50 univariate analysis 50 suicide attempters 50 suicidal ideation 50 symptom checklist 50 MMSE scores 50 somatic symptoms 50 HRQL 50 Exclusion criteria 50 familial aggregation 50 bipolar disorders 50 substance induced psychosis 50 investigational atypical antipsychotic 50 opioid dependent 50 corticosteroid dose 50 comorbid disorders 50 interquartile range 50 primary endpoint 50 Suicidal ideation 50 comorbid psychiatric disorders 50 BMI z 50 depressive episode 50 adjunctive placebo 49 nonobese 49 delusions hallucinations 49 YMRS 49 primary hypercholesterolemia 49 generalized anxiety disorder 49 aged ≥ 49 estimated GFR 49 affective psychoses 49 depressive episodes associated 49 placebo controlled clinical trials 49 premenstrual dysphoric disorder 49 logistic regression analysis 49 comorbid anxiety 49 mg BID dose 49 composite endpoint 49 prodromal symptoms 49 Sociodemographic 49 Asperger disorder 49 hypomanic episode 49 MetS 49 undetectable HBV DNA 49 PANSS 49 oral naltrexone 49 IBS C 49 Mental Disorders 4th 49 Statistical Manual 49 genotypic resistance 49 interpersonal psychotherapy 49 % CI #.#-#.# [003] 49 comorbid ADHD 49 neuroleptic 49 CORE OM 49 SSRI citalopram 49 alexithymia 49 serum HCV RNA 49 Diagnostic Interview 49 Posttraumatic Stress Disorder PTSD 49 hypomanic episodes 49 psychiatric disorder 49 EDNOS 49 somatization 49 EDSS scores 49 baseline HbA1c 49 attain statistical significance 49 Montgomery Asberg Depression 49 SSRI SNRI 49 borderline personality disorder 49 CR nPR 49 Kaplan Meier analysis 49 endoscopic remission 48 late onset hypogonadism 48 histologically confirmed 48 moderate renal impairment 48 EQ 5D 48 Multivariate analysis 48 Y BOCS 48 NIHSS score 48 psychopathological symptoms 48 dissociative symptoms 48 retest reliability 48 dietary questionnaires 48 shorter telomere length 48 attention-deficit/hyperactivity disorder ADHD 48 NNT = 48 semistructured interviews 48 preintervention 48 bivariate analyzes 48 diagnosable disorder 48 comorbidities 48 prodromal 48 diarrhea predominant IBS 48 methotrexate monotherapy 48 adjunctive ABILIFY 48 RESIST studies 48 Expanded Disability Status 48 neurocognitive function 48 Rating Scale MADRS 48 Anxiety disorders 48 Unified Parkinson Disease 48 System IPSS 48 ECOG PS 48 cognitively intact 48 multivariate logistic regression 48 HADS 48 comorbid conditions 48 cognitive affective 48 Solid Tumors criteria 48 pramipexole 48 HbA 1c levels 48 oppositional defiant disorder 48 manic hypomanic 48 MDD 48 citalopram 48 schizoaffective disorder 48 neuropsychological assessment 48 interrater reliability 48 nonadherent 48 mania hypomania 48 albumin excretion 48 sociodemographic factors 48 dose escalation phase 48 erection hardness 48 adenotonsillectomy 48 depressive symptom 48 secondary endpoints 48 persecutory delusions 48 bipolar mania 48 point Likert scale 48 elevated ALT 48 CDAI score 48 schizoaffective disorders 48 generalized anxiety disorder GAD 48 QIDS SR 48 Pharmacokinetic parameters 48 timepoints 48 STEP BD 48 generalized epilepsy 48 % CI #.#-#.# [004] 48 interpersonal psychotherapy IPT 48 episodic migraine 48 intraclass correlation coefficients 48 schizotypal personality disorder 48 df = 48 mITT population 48 amoxicillin clavulanate 48 psychostimulants 48 univariate 48 liver histology 48 logistic regression 47 nondepressed 47 fluoxetine paroxetine 47 #q#.# deletion syndrome 47 Depression Rating Scale 47 DSM IV SCID 47 lowest tertile 47 tumor histology 47 College Readiness Benchmarks 47 meta regression 47 psychopathology 47 Oppositional Defiant Disorder 47 diagnosable 47 dosage regimens 47 INVEGA ® 47 subclinical hypothyroidism 47 acamprosate 47 Solid Tumors RECIST 47 syndromic 47 THIS STUDY 47 diagnosable mental illness 47 Hb A1C 47 divalproex sodium 47 PREZISTA r 47 Female Sexual Function 47 schizotypal 47 Primary endpoints 47 eszopiclone 47 p = .# [002] 47 Logistic regression analysis 47 Baseline characteristics 47 DAS# CRP 47 certolizumab 47 secondary efficacy endpoint 47 #mg/day [001] 47 ALT flares 47 EPDS 47 CI -#.# 47 pharmacotherapies 47 depressive episodes 47 depression dysthymia 47 lipid lowering agents 47 Diagnostic Criteria 47 haematologic 47 % CI #.#-#.# [007] 47 Wechsler Memory 47 nonobese patients 47 obsessive compulsive disorders 47 secondary endpoint 47 autonomic dysfunction 47 multiple logistic regression 47 psychodynamic therapy 47 Symptom Checklist 47 thyrotropin levels 47 Edinburgh Postnatal Depression 47 plasma cortisol 47 psychiatric hospitalization 47 Distress Scale 47 Symptom severity 47 amisulpride 47 adjuvant systemic 47 acute bipolar mania 47 PEGINTRON TM 47 clinically meaningful improvement 47 Maastricht criterion 47 schizotypal traits 47 IOP lowering 47 neuroleptics 47 internalizing disorders 47 completers 47 serotonin reuptake inhibitors 47 preconceived ideologies 47 olanzapine LAI 47 Rating Scale BPRS 47 lipid lowering medications 47 fraternal twin pairs 47 chronicity 47 PASI scores 47 subscore 47 guanfacine extended release 47 HBeAg negative patients 47 alanine aminotransferase ALT 47 Major Depressive Disorder MDD 47 non metastatic osteosarcoma 47 HIV uninfected 47 polysubstance abuse 47 prucalopride 47 Secondary efficacy endpoints 46 Interpersonal psychotherapy 46 bipolar illness 46 cognitive behavioral 46 D constipation predominant 46 RLS symptoms 46 prospectively enrolled 46 T2DM 46 opiate dependence 46 Duloxetine 46 temper dysregulation disorder 46 quetiapine XR 46 PNH patients 46 Fitch AAAmmf rating 46 NYHA functional class 46 Index FSFI 46 Crohn Disease Activity 46 impaired fasting glucose 46 Non inferiority 46 guideline concordant 46 Subgroup analyzes 46 MADRS 46 psychiatric hospitalizations 46 antiepileptics 46 posttest 46 nonfatal MI 46 overactive bladder symptoms 46 â ‰ ¥ 46 NSDUH 46 HbA1c levels 46 RLS sufferers 46 dopaminergic therapy 46 ADHD RS 46 PDD NOS 46 antidiabetic medications 46 HbA 1c 46 retrospective cohort 46 multivariable Cox 46 hemoglobin A1c levels 46 polysomnography PSG 46 lifetime abstainers 46 comorbid substance 46 criterion 46 VaD 46 Comorbidity 46 umol L 46 oxcarbazepine 46 Pfizer reanalyzed 46 creatinine clearance 46 CANCIDAS 46 TEAEs 46 TLUS 46 NSQIP 46 % CI #.#-#.# [008] 46 Hypoactive Sexual Desire Disorder 46 hypomanic 46 CCyR 46 anemia hemoglobin 46 psychosocial variables 46 paroxysmal AF 46 APOE genotype 46 prior chemotherapy regimens 46 Scale EDSS score 46 DAS# [002] 46 spirometric 46 chemoradiation therapy 46 methotrexate therapy 46 antidepressant efficacy 46 neurocognitive impairment 46 nephrotic syndrome NS 46 highest tertile 46 partial onset seizures 46 randomized controlled trials RCTs 46 depression bipolar disorder 46 pCR 46 apnea hypopnea index 46 oxycodone CR 46 CDAI 46 nonadherence 46 rALLy trial 46 underwent CABG 46 multivariable analysis 46 NAMCS 46 nmol L 46 NYHA Class III 46 IIEF 46 antihypertensive therapy 46 ziprasidone 46 anxiolytic 46 elevated LDH 46 manic depressive illness 46 habitual snoring 46 Secondary endpoints 46 Maastricht criteria 46 mild renal insufficiency 46 semistructured 46 Clinician Administered PTSD 46 depressive disorder 46 C1 INH deficiency 46 FDG PET scans 46 mg/m2 dose 46 coinfected patients 46 dementia praecox 46 sticks potato puffs 46 neurocognitive functioning 46 relapsed MM 46 placebo controlled trials 45 externalizing disorders 45 MAS XR 45 virologic response EVR 45 tipranavir r 45 baseline LDH 45 nonpregnant women 45 ADAS cog 45 cranial irradiation 45 CI = 45 convergent validity 45 tapentadol ER 45 constipation OIC 45 aspartate aminotransferase AST 45 Excessive daytime sleepiness 45 HRQOL 45 mIU L 45 specific antigen PSA 45 aripiprazole 45 MGUS 45 Depression Inventory 45 anorexia nervosa bulimia 45 null responder HCV 45 Comorbidities 45 NESARC 45 prospectively stratified 45 plasma pharmacokinetics 45 virologic failure 45 serum HBV DNA 45 AUDs 45 HDRS 45 mg BID 45 5-FU/LV 45 postdischarge 45 antisocial traits 45 antiepileptic drugs 45 surrogate markers 45 continuously abstinent 45 refractory AML 45 hsCRP levels 45 tonsillar hypertrophy 45 schizoaffective 45 abstainers 45 attempters 45 Meta analyzes 45 ng dL 45 efavirenz EFV 45 psychotic disorder 45 nulliparous women 45 Mental Disorders 4th edn 45 COMT genotype 45 prognostic variables 45 mITT 45 ASPD 45 CIM Definition Standards 45 GAMMAGARD 45 PTSD symptoms 45 #mg/dl 45 personality disorders 45 tipranavir ritonavir 45 Incontinence Impact Questionnaire 45 NIHSS 45 tranylcypromine 45 serum GGT 45 nonadopted 45 acetabular fracture 45 mcg albinterferon alfa 2b 45 BENICAR HCT 45 neuropsychological assessments 45 anorexia nervosa bulimia nervosa 45 virologic response 45 Scale EDSS 45 primary aldosteronism 45 MS DRGs 45 CTEPH 45 State Trait Anxiety 45 antidepressant therapy 45 Neuroticism 45 Pathological gambling 45 hypogonadal men 45 eC SSRS 45 T1DM 45 typical antipsychotics 45 ragweed allergic 45 paraphilia 45 microalbuminuria 45 PSADT 45 ONGLYZA saxagliptin 45 clinical endpoints 45 psychotic illnesses 45 evaluable subjects 45 Univariate analysis 45 virological failure 45 Pain Rating Scale 45 PHQ 9 45 tolterodine 45 mL/min/#.# m 2 45 Pervasive Developmental Disorder 45 ictal 45 UKPDS 45 CSBMs 45 RCTs 45 bosentan 45 mg Pycnogenol 45 serum lipid levels 45 NATRECOR R 45 depression suicidal ideation 45 neuropsychological functioning 45 RLAI 45 achieved ACR# 45 Bonferroni correction 45 Operative mortality 45 AGILECT R 45 aminotransferase levels 45 mcg BID 45 conventional antipsychotics 45 genital arousal 45 intravesical therapy 45 MDQ 45 invasive ductal breast cancer 45 plasma glucose concentration 45 clinicopathological features 45 Komisarjevsky writings 45 antidepressants antipsychotics 45 neuropsychological evaluations 45 IBDQ 45 subthreshold depression 45 isocaloric 45 Adjuvant therapy 45 RECIST Response Evaluation Criteria 45 Subgroups 45 clomipramine 45 serum estradiol 45 Major depressive disorder 45 STRIDE PD 45 CIM definitions 45 nondemented 45 macroalbuminuria 45 levetiracetam 45 hepatitis C genotype 45 relapsed GBM 45 hyperarousal 45 liver biopsies 45 Postoperative complications 45 prescribed antipsychotic medication 45 subclinical hyperthyroidism 45 interrater 45 lamotrigine 45 migraineurs 45 pharmacologic treatments 45 neuropsychological tests 45 cryptogenic 45 Atomoxetine 45 pregabalin 45 hepatic encephalopathy 45 salivary cortisol 45 NHANES III 45 nondiabetic patients 45 actigraphy 45 confidence intervals CIs 45 LUTS 45 HBeAg negative 45 median PFS 45 ischemic cardiomyopathy 45 generalized anxiety 45 DPNP 45 predictive validity 45 postprocedure 45 Poisson regression 45 tertiles 45 sociodemographic 45 dissociative disorders 45 multivariable logistic regression 45 AGHD 45 IQR 45 body dysmorphic disorder 45 unprovoked seizures 44 confidence interval CI 44 migraine prophylaxis 44 underwent liver transplantation 44 subtrochanteric 44 severe exacerbations 44 postoperative complication 44 1mg dose 44 pharmacological interventions 44 posttraumatic stress disorder PTSD 44 NCCN guidelines 44 EFFEXOR XR 44 nmol L. 44 antiepileptic medications 44 Treatment Resistant 44 ADAS Cog 44 8mg/kg 44 MEND CABG II 44 confusional 44 psychotherapeutic drugs 44 NHAMCS 44 rs# [004] 44 eplerenone 44 Not Otherwise Specified 44 insulin detemir 44 dysphoric 44 stage IIIB 44 emotional lability 44 olanzapine quetiapine 44 placebo PBO 44 HRQoL 44 bivariate 44 GH deficiency 44 Score DAS# 44 recurrent glioblastoma multiforme 44 Interrater reliability 44 Replication NCS R 44 blind placebo 44 opioid dependence 44 divalproex 44 airway responsiveness 44 viral kinetics 44 MMSE 44 hematopoietic cancers 44 Severe Primary IGFD 44 glycated hemoglobin 44 quetiapine risperidone 44 Gwinnett Woodworkers Association 44 Eligibility criteria 44 Kraepelin 44 Mood disorders 44 HBeAg positive patients 44 tricyclic antidepressant 44 GnRH agonist 44 akinetic mutism 44 ozone NAAQS 44 Rating Scale UPDRS 44 WOMAC scores 44 nomograms 44 diabetes mellitus DM 44 Logistic regression 44 prostatic hyperplasia 44 nanoFLEX IOL 44 bladder carcinoma 44 agomelatine 44 AGILECT ® 44 atypical antipsychotic medications 44 anhedonia 44 Pain Intensity 44 KRAS status 44 mentally disordered sex offender 44 VADT 44 suicidal ideations 44 Depressive Symptoms 44 ELBW infants 44 posttraumatic stress disorder 44 respective honeymoons 44 psychiatric inpatients 44 Preoperatively 44 logistic regression analyzes 44 n = 44 glycated hemoglobin levels 44 familial pancreatic cancer 44 patients evaluable 44 evaluable 44 akathisia 44 DRD2 44 extrapyramidal symptoms 44 Cognitive impairment 44 Electroconvulsive therapy 44 SRBD 44 undergoing coronary angiography 44 HAQ DI 44 KRAS mutations occur 44 tricyclic antidepressants 44 microbiologically evaluable 44 proband 44 dually diagnosed 44 HSCT 44 liver transplant recipients 44 unprotected receptive anal 44 timepoint 44 SCr 44 efficacy evaluable 44 histological subtype 44 hypercalciuria 44 NIH CPSI 44 Accounting Standard AASB 44 Geriatric Depression 44 HSDD 44 hypopneas 44 Kaplan Meier estimate 44 atypical neuroleptics 44 habitual snorers 44 OSAHS 44 abstinent 44 ADCS ADL 44 remission induction 44 androgen deficiency 44 VFQ 44 annualized relapse 44 HUMIRA adalimumab 44 hepatic enzyme 44 MCyR 44 adverse cytogenetics 44 morphometric vertebral fractures 44 β blockers 44 stage IIIb IV 44 psychiatric disorders 44 depression generalized anxiety 44 imipramine 44 sUA 44 opioid prescriptions 44 bipolar disorder 44 serum uric acid 44 mg kg dose 44 risperidone olanzapine 44 Wechsler Adult 44 MIRAPEX ER 44 ≥ 44 AEC Q# 44 manufactures VIVITROL ® 44 prespecified 44 symptom exacerbation 44 metformin monotherapy 44 K ras mutations 44 Personality Disorder 44 subgroup 44 conjugated equine estrogen 44 acute manic 44 null hypothesis 44 periprocedural MI 44 carotid IMT 44 primary generalized tonic 44 solifenacin 44 neuropsychiatric symptoms 44 radiographic progression 44 urinary N telopeptide 44 antidiabetic medication 44 WOMAC pain 44 seroconverted 44 potential confounding variables 44 emotional dysregulation 44 unresectable malignant mesothelioma UMM 44 impulsivity characteristic 44 Change PGIC 44 ribavirin RBV 44 chi squared 44 polysomnographic 44 refractory epilepsy 44 Edition DSM IV 44 symptomatic VTE 44 concomitant medications 44 haloperidol Haldol 44 adenocarcinoma histology 44 ANCOVA 44 K ras mutation 44 DMARD 44 dyslipidaemia 44 relapsed refractory multiple myeloma 44 BMI percentile 44 serum cotinine 44 Child Behavior Checklist 44 Key secondary endpoints 44 COMBIVIR 44 acute mania 44 Doxil ® 44 #,# methylenedioxymethamphetamine 44 chlamydial infection 44 zonisamide SR 44 antipsychotic efficacy 44 unmedicated 44 dosing cohort 44 serum vitamin D 44 Descriptive statistics 44 ACR# ACR# 44 serum phosphorous 44 obstructive sleep apnea hypopnea 44 Spectrum Disorders 44 systolic dysfunction 44 mg dL 44 Bulimia Nervosa 44 Comorbid 44 CVD mortality 44 retinal thickness 44 SCHIZOPHRENIA DISORDERS SUPPORT GROUP 44 Diseases Ninth 44 Hypogonadism 44 eligibility criteria 44 Subgroup analysis 44 antihypertensive agents 44 Swedish Mammography Cohort 44 nonfasting triglyceride levels 44 Text Revision 43 Atypical antipsychotics 43 parous women 43 Personality disorders 43 hypogonadal 43 neuropsychological evaluation 43 echocardiographic parameters 43 bortezomib refractory 43 neuropsychological deficits 43 non inferiority 43 Regression analyzes 43 clinically meaningful improvements 43 socio demographic 43 follicular lymphoma FL 43 BMI ≥ 43 postrelease supervision 43 undergone bariatric surgery 43 symptomatic intracerebral hemorrhage 43 atopic 43 hematologic toxicity 43 chlorambucil 43 chlorpromazine 43 bacterial prostatitis 43 JEDEC specifications 43 psychosis 43 HOMA IR 43 APTIVUS r 43 5 HT2A 43 GSK# [001] 43 surrogate endpoint 43 nonepileptic seizures 43 constipation predominant 43 mood disorders 43 highly emetogenic 43 hippocampal volumes 43 COPAXONE R 43 neuropsychological impairments 43 Lu AA# 43 μmol L 43 blepharospasm 43 NYHA class 43 Logistic regression analyzes 43 active comparator 43 mood dysregulation 43 aminotransferases 43 diastolic blood pressures 43 serum phosphate levels 43 Psoriasis Area 43 baseline FEV 43 coronary calcification 43 Mental retardation 43 disulfiram 43 virologic breakthrough 43 phase IIIb 43 Social Phobia 43 OGTT 43 psychiatric disorders ATI 43 intracranial hypertension 43 ATACAND 43 PROMETA 43 low dose cytarabine 43 seropositivity 43 definite stent thrombosis 43 Clinical Practice Guideline 43 functional dyspepsia 43 CIMZIA ™ 43 neuroleptic drugs 43 androgen depletion 43 TT genotype 43 HCV SPRINT 43 AYP benchmarks 43 Suicidality 43 clinicopathologic 43 syncopal 43 meta analytic 43 use disorders AUDs 43 distinct subtypes 43 somnolence sleepiness 43 dysarthria 43 SILENOR TM 43 dose proportionality 43 Main Outcome Measures 43 4mg/kg 43 ego dystonic 43 mCRC patients 43 asymptomatic carotid stenosis 43 aetiology 43 Acute Myeloid Leukaemia AML 43 intermittent exotropia 43 intraobserver 43 neurodevelopmental impairment 43 puerperal psychosis 43 atypical antipsychotic medication 43 antihypertensive medications 43 NPH insulin 43 autoimmune thyroid 43 asymptomatic hyperuricemia 43 serum testosterone 43 relapsed SCLC 43 Binge Eating Disorder 43 fasting glucose 43 criterions 43 motivational interviewing 43 ACR# response 43 MoxDuo TM IR 43 Likert scale 43 lopinavir r arm 43 undergoing peritoneal dialysis 43 ARV regimens 43 Reagins Lilly 43 Inpatients 43 Timed Walk 43 peginterferon 43 psychotropic medication 43 parkinsonian 43 preoperatively 43 biochemical recurrence 43 histologically proven 43 CFR pt 43 pain catastrophizing 43 quetiapine 43 histologic subtype 43 colorectal neoplasia 43 Heritability 43 Couey IQ 43 PSQI 43 Screening Questionnaire 43 IPSS 43 HbA1C levels 43 decrements 43 Corlux 43 QTcF 43 abstinent alcoholics 43 depression anxiety 43 CC genotype 43 endophenotypes 43 attention-deficit/hyperactivity disorder 43 squamous cell histology 43 civilian noninstitutionalized population 43 fluoxetine Prozac 43 hours postdose 43 hyperactivity impulsivity 43 rimonabant #mg 43 heterozygous familial 43 dysthymic