Related by context. All words. (Click for frequent words.) 76 pegylated liposomal doxorubicin 76 etoposide 75 5-FU/LV 75 adriamycin 75 fluorouracil 74 FOLFIRI 73 carboplatin paclitaxel 73 Irinotecan 73 idarubicin 72 docetaxel chemotherapy 72 cisplatin 72 mitoxantrone 72 sorafenib Nexavar 72 daunorubicin 72 epirubicin 72 5 FU 72 CHOP chemotherapy 72 bleomycin 72 chlorambucil 72 TACE 72 Gemcitabine 72 dacarbazine 72 chemoradiotherapy 71 Doxil ® 71 topotecan 71 XELOX 71 EBRT 71 Fludara 71 gemcitabine Gemzar 71 estramustine 71 FOLFOX6 71 taxane chemotherapy 70 hepatic metastases 70 FOLFOX 70 trabectedin 70 temozolomide 70 cyclophosphamide methotrexate 70 Pemetrexed 70 paclitaxel Taxol 70 docetaxel Taxotere 70 relapsed ovarian cancer 70 cyclophosphamide 70 doxorubicin 70 Camptosar ® 70 5 fluorouracil 70 gemcitabine cisplatin 70 gemcitabine 70 goserelin 70 Cisplatin 70 docetaxel 70 FOLFOX4 70 Peg IFN 69 mycophenolate mofetil 69 radiotherapy RT 69 gemcitabine carboplatin 69 azacitidine 69 oxaliplatin 69 trastuzumab 69 cisplatin chemotherapy 69 CsA 69 gemcitabine chemotherapy 69 Lenalidomide 69 interferon alfa 2a 69 idraparinux 69 antiandrogen 69 ABVD 69 oblimersen 69 chemotherapy docetaxel 69 DOXIL 69 metastatic renal cell carcinoma 69 lenalidomide dexamethasone 69 paclitaxel carboplatin 69 neoadjuvant chemotherapy 69 Fludarabine 69 pegylated interferon alfa 69 vinorelbine 68 nab paclitaxel 68 Fluorouracil 68 interferon alfa 2b 68 FOLFIRI alone 68 octreotide LAR 68 dexamethasone Decadron 68 overlapping toxicities 68 chemoradiation 68 erlotinib Tarceva ® 68 cytotoxic chemotherapy 68 decitabine 68 6 mercaptopurine 68 debulking surgery 68 chemoradiation therapy 68 Taxol paclitaxel 68 bendamustine 68 low dose cytarabine 68 mg kg dose 68 interferon alfa 68 5 FU leucovorin 68 Hycamtin ® 68 fulvestrant 68 Cyclophosphamide 68 FUSILEV enhances 68 4mg/kg 68 ritonavir boosted 68 chemotherapeutic drug 68 bevacizumab 68 piperacillin tazobactam 68 Etoposide 68 ribavirin RBV 68 IFN α 68 imatinib Gleevec 68 zoledronic acid 68 intravesical 68 cetuximab 68 Capecitabine 68 abacavir lamivudine 68 postoperative chemotherapy 68 dose cytarabine 68 vincristine 67 neurologic progression 67 DOXIL ® 67 fludarabine 67 Trastuzumab 67 Erlotinib 67 azacytidine 67 mitomycin C 67 liposomal doxorubicin 67 ethambutol 67 external beam radiotherapy 67 bevacizumab Avastin 67 mitomycin 67 radiochemotherapy 67 doxorubicin cyclophosphamide 67 thalidomide Thalomid 67 temsirolimus 67 docetaxel Taxotere ® 67 mTOR inhibitors 67 azathioprine 67 concurrent chemoradiation 67 metastatic malignant 67 Flu Cy 67 fluoropyrimidine 67 peginterferon alfa 2a 67 biochemical relapse 67 Temozolomide 67 salmeterol fluticasone 67 immunomodulatory therapy 67 relapsed CLL 67 trans retinoic acid 67 mCRC patients 67 bevacizumab Avastin ® 67 bevacizumab Avastin R 67 Platinol 67 lopinavir r 67 BEACOPP 67 refractory AML 67 telaprevir dosed 67 DMARDs 67 DFMO 67 Combination therapy 67 5 Fluorouracil 67 trastuzumab Herceptin ® 66 alkylating agent 66 bortezomib 66 ibandronate 66 isoproterenol 66 irinotecan chemotherapy 66 adalimumab Humira 66 paclitaxel chemotherapy 66 Adjuvant chemotherapy 66 amphotericin B 66 placebo dexamethasone 66 flutamide 66 Elitek 66 pemetrexed 66 preoperative chemotherapy 66 leucovorin 66 pamidronate 66 locoregional recurrence 66 chemotherapeutic regimens 66 standard chemotherapy regimens 66 platelet inhibitor 66 cidofovir 66 pneumonectomy 66 TNF inhibitor 66 fluticasone salmeterol 66 irbesartan 66 nadolol 66 melphalan prednisone 66 mapatumumab 66 clodronate 66 Cremophor 66 Docetaxel 66 oxaliplatin Eloxatin 66 oral Hycamtin 66 PegIFN RBV 66 interferon ribavirin 66 FluCAM 66 capecitabine 66 cinacalcet 66 LEXIVA r 66 CR nPR 66 neoadjuvant therapy 66 Mitoxantrone 66 fibrinolysis 66 vorinostat 66 Thal Dex 66 Pegylated Interferon 66 Navelbine 66 infusional 5-FU/LV 66 peginterferon 66 cytoreduction 66 Mitomycin C 66 PegIFN 66 alfa 2a 66 mRCC 66 adalimumab 66 CIMZIA TM 66 LHRH agonist 66 caspofungin 66 pyrazinamide 66 fluorouracil leucovorin 66 dose dexamethasone 66 dexamethasone 66 cytarabine 66 NMIBC 66 oral allopurinol 66 #mg/m# [001] 66 plus dexamethasone 66 uM 66 Fulvestrant 66 Gleevec resistant 65 cetuximab Erbitux R 65 Bevacizumab 65 DAPT 65 chemotherapy cisplatin 65 clopidogrel Plavix 65 infusional 65 Paraplatin ® 65 irinotecan 65 Taxol ® 65 oral clodronate 65 cisplatin carboplatin 65 standard chemotherapy regimen 65 eplerenone 65 IFN beta 65 chemoembolization 65 sorafenib Nexavar ® 65 sunitinib malate 65 DMARD 65 Taxotere ® 65 CIMZIA ™ 65 teriflunomide 65 Oxaliplatin 65 gefitinib Iressa 65 prednisone prednisolone 65 docetaxel prednisone 65 steroid dexamethasone 65 octreotide 65 cyclophosphamide chemotherapy 65 neoadjuvant 65 xenograft models 65 dasatinib Sprycel ® 65 erlotinib Tarceva 65 denileukin diftitox 65 corticosteroid therapy 65 biologic therapy 65 IFN alfa 65 pharmacologically active isomer 65 intravenous bisphosphonates 65 Herceptin trastuzumab 65 Leucovorin 65 Interferon alfa 65 esomeprazole 65 8mg/kg 65 saline placebo 65 imipenem 65 Trabectedin 65 epoprostenol 65 micafungin 65 cisplatin gemcitabine 65 Gefitinib 65 chemotherapy FOLFOX 65 tiotropium bromide 65 chemotherapies 65 cetuximab Erbitux ® 65 comparator arm 65 median PFS 65 relapsed MM 65 luteinizing hormone releasing 65 vandetanib 65 Cytoxan 65 Doxorubicin 65 androgen deprivation 65 timolol 65 zoledronate 65 mg m² 65 Paraplatin ® carboplatin 65 fibrinolytic 65 melphalan 65 Doxil 65 FOLPI 65 Taxotere docetaxel 65 erlotinib 65 amikacin 65 Torisel 65 chemotherapeutic agents 65 KRAS mutant tumors 65 sorafenib 65 cis retinoic acid 65 paricalcitol 65 LHRH agonists 65 dacarbazine DTIC 65 biologic DMARD 65 hematologic toxicity 65 tumor xenograft models 65 capecitabine Xeloda 65 beclomethasone dipropionate 65 rFSH 65 tirofiban 65 cefuroxime 65 paclitaxel Taxol ® 65 methotrexate therapy 65 ULORIC 65 anti leukemic 65 temozolomide TMZ 64 antithymocyte globulin 64 intravenous cyclophosphamide 64 tumor necrosis 64 3TC lamivudine Epivir 64 Platinol ® 64 abciximab 64 mitoxantrone chemotherapy 64 aspirin clopidogrel 64 dasatinib Sprycel 64 APTIVUS r 64 deferoxamine 64 Pertuzumab 64 CANCIDAS 64 achieved ACR# 64 Alkeran 64 thiazide diuretic 64 Peginterferon 64 paclitaxel Taxol R 64 μg ml 64 Vidaza azacitidine 64 thienopyridine 64 imatinib therapy 64 L asparaginase 64 TEMODAL 64 receptor tyrosine kinase inhibitor 64 IFN alpha 64 MGd 64 #mg BID [003] 64 pegfilgrastim 64 Topotecan 64 plus ribavirin 64 fondaparinux 64 TAXOTERE R 64 uric acid lowering 64 ximelagatran 64 Dasatinib 64 paclitaxel 64 boosted protease inhibitor 64 metastatic RCC 64 trimethoprim sulfamethoxazole 64 calcineurin inhibitors 64 ganciclovir 64 bicalutamide 64 anti androgen 64 lung metastases 64 tenecteplase 64 Hycamtin 64 voriconazole 64 androgen ablation 64 gemcitabine Gemzar ® 64 NRTIs 64 partial remissions 64 adjuvant therapy 64 GnRH agonist 64 cytarabine daunorubicin 64 Epirubicin 64 trans retinoic acid ATRA 64 nicardipine 64 N acetylcysteine 64 weekly subcutaneous injections 64 levofloxacin 64 carboplatin 64 intravesical therapy 64 glargine 64 paroxysmal AF 64 Platinol ® cisplatin 64 AZT zidovudine Retrovir 64 Q2W 64 rituximab Rituxan 64 ceftriaxone 64 iodixanol 64 PSA nadir 64 Gliadel Wafer 64 oral diclofenac 64 xanthine oxidase inhibitor 64 somatostatin analog 64 chemoresistant 64 adjuvant radiotherapy 64 antimetabolite 64 care regimens CCR 64 VELCADE melphalan 64 SCCHN 64 epirubicin cyclophosphamide 64 atorvastatin #mg 64 MabCampath 64 Neoadjuvant 64 colorectal liver metastases 64 nucleoside analog 64 dipyridamole 64 colorectal carcinoma 64 TNF α 64 glatiramer acetate 64 inotropic 64 QVAR R 64 nelfinavir 64 mcg BID 64 posaconazole 64 effector function 64 resectable 64 ropivacaine 64 cyclophosphamide Cytoxan 64 immunosuppressant 64 Aptivus ® 64 cytotoxic therapy 64 LPV r 64 advanced hepatocellular carcinoma 64 pegylated interferon alfa 2b 64 allogeneic SCT 64 receptor blocker 64 ara C 64 chemotherapy gemcitabine 64 tolterodine ER 64 peginterferon alfa 2b 64 CA4P 64 leukemia AML 64 systemic corticosteroid 64 ^ sup #m 64 fallopian tube carcinoma 64 Bortezomib 64 protease inhibitor PI 64 rHuEPO 64 cytotoxic 64 GISTs 64 Seliciclib 64 refractory NSCLC 64 anastrozole 64 EGFR TKI 64 tamsulosin 64 androgen blockade 64 tegafur 63 fallopian tube cancers 63 KRAS wild 63 Caelyx 63 anthracycline taxane 63 mCi 63 fluvastatin 63 somatostatin analogues 63 imatinib 63 PSADT 63 Peginterferon Alfa 2a 63 paclitaxel poliglumex 63 ALND 63 ® lenalidomide 63 recurrent glioblastoma multiforme 63 tigecycline 63 Folfox 63 active metabolite 63 Cytarabine 63 antitumor effect 63 intravenously administered 63 folinic acid 63 adjuvant chemotherapy 63 cytoreductive surgery 63 olmesartan 63 dimeglumine 63 myelosuppressive 63 Pegylated Liposomal Doxorubicin 63 trastuzumab Herceptin 63 ug kg 63 myeloablative 63 Hazard Ratio 63 Vandetanib 63 bacillus Calmette Guerin 63 mmol kg 63 severe neutropenia 63 HMG CoA reductase inhibitor 63 adjuvant radiation 63 gastrointestinal stromal tumors 63 lapatinib Tykerb 63 cytostatic 63 lymphadenectomy 63 cisplatin vinorelbine 63 budesonide 63 rituximab 63 Pharmacokinetics PK 63 Nilotinib 63 cisplatin resistant 63 fluconazole 63 metastatic malignant melanoma 63 intraperitoneal injection 63 indinavir 63 Taxotere chemotherapy 63 GnRH agonists 63 pCR 63 μmol L 63 HBeAg seroconversion 63 Halaven 63 corticosteroid dexamethasone 63 tolterodine 63 doxorubicin docetaxel 63 p = NS 63 K ras mutations 63 bupivacaine 63 basiliximab 63 β blockers 63 antiemetic 63 Desferal 63 clomipramine 63 PegIntron 63 virologic response 63 q8h 63 cabazitaxel 63 oral levofloxacin 63 imatinib Gleevec ® 63 sulfasalazine 63 trastuzumab Herceptin R 63 intravesical instillation 63 plus prednisone prednisolone 63 tocilizumab 63 QD dosing 63 Taxotere 63 sunitinib 63 Orally administered 63 thromboembolic events 63 unfractionated heparin 63 Vfend 63 tyrosine kinase inhibitor 63 locoregional 63 pegylated interferon alfa 2a 63 Peginterferon alfa 2b 63 interferon therapy 63 Camptosar ® irinotecan 63 Carboplatin 63 complete cytogenetic response 63 Bevacizumab Avastin 63 IV bolus 63 receiving VICTRELIS 63 cyclosporin 63 isoenzyme 63 bosentan 63 tiotropium 63 TNF inhibitors 63 irinotecan doxorubicin oxaliplatin paclitaxel 63 Vinorelbine 63 dasatinib 63 degarelix 63 plus gemcitabine 63 tinidazole 63 stage IIIB 63 administered subcutaneously 63 mitoxantrone plus 63 ovarian carcinoma 63 imiquimod cream 63 chemotherapeutic agent 63 peginterferon alpha 2a 63 mycophenolate mofetil MMF 63 pyridostigmine 63 ixabepilone 63 ELOXATIN 63 calcineurin inhibitor 63 Neulasta ® 63 subcutaneously administered 63 PEGylated anti 63 TMP SMX 63 DMARDS 63 GHRH 63 hypomethylating agents 63 amrubicin 63 lumbar spine BMD 63 docetaxel Taxotere R 63 demethylating agent 63 nephrotoxic 63 TMC# r 63 chemotherapy regimens 63 Vidofludimus 63 allopurinol 63 intravitreal injections 63 anti angiogenic agent 63 #mg/kg [002] 63 plasma kallikrein inhibitor 63 CLL SLL 63 cystectomy 63 Bleomycin 63 lenalidomide Revlimid R 63 pomalidomide 63 recurrent NSCLC 63 amprenavir 63 alkylating agents 63 cardiac toxicity 63 rizatriptan 63 tamoxifen Nolvadex ® 63 Bezielle 63 NRTI 63 zolmitriptan 63 cediranib 63 pertuzumab 63 gastrointestinal stromal tumors GIST 63 YONDELIS 63 nephrectomy 63 superficial bladder cancer 63 Fludara ® 63 sirolimus eluting stent 63 indomethacin 63 Toxicities 63 abiraterone acetate 63 cyclophosphamide doxorubicin vincristine 63 Cetuximab 63 ritonavir boosted lopinavir 63 surgical debulking 63 tipranavir 63 gefitinib 63 adjunctive placebo 63 mutated KRAS 63 Dacogen decitabine 62 Sorafenib 62 vinca alkaloids 62 methotrexate 62 atazanavir ritonavir 62 lapatinib 62 Pegasys plus Copegus 62 cilengitide 62 tibolone 62 dalteparin 62 rhTSH 62 Natalizumab 62 Degarelix 62 cytoreductive nephrectomy 62 conventional DMARDs 62 mTOR inhibitor 62 radioiodine therapy 62 sunitinib Sutent ® 62 operable breast cancer 62 Interferon beta 62 tenofovir Viread 62 beta 1a 62 plus prednisone 62 immunostimulatory 62 vinca alkaloid 62 interferon beta 1a 62 liver metastasis 62 intramuscularly 62 PEGylated Fab fragment 62 peg interferon 62 ARB telmisartan 62 imetelstat 62 captopril 62 G CSF 62 letrozole Femara 62 eptifibatide 62 #mg BID [001] 62 5 fluorouracil leucovorin 62 chemo radiotherapy 62 TTF Therapy 62 VAPRISOL 62 Akt activation 62 IIIa inhibitor 62 carmustine 62 CCyR 62 PEG IFN 62 anthracyclines 62 enzyme inhibitor 62 sulphonylurea 62 squamous cell carcinoma SCC 62 ERK1 2 62 TNFa 62 leflunomide 62 Navelbine ® 62 selegiline 62 remifentanil 62 locoregional disease 62 efavirenz EFV 62 pharmacokinetic interactions 62 Pegasys peginterferon alfa 2a 62 #.#g/day 62 EGFR tyrosine kinase inhibitors 62 HDACi 62 Amrubicin 62 anthracycline chemotherapy 62 plus 5-FU/LV 62 alpha interferons 62 Procoralan 62 transarterial chemoembolization 62 tacrolimus ointment 62 Bosentan 62 HER2 positive metastatic breast 62 adjuvant tamoxifen 62 CDK inhibitor 62 antiangiogenic agent 62 xenograft model 62 Xeloda capecitabine 62 rosuvastatin #mg 62 Imatinib 62 efalizumab 62 cilostazol 62 paclitaxel cisplatin 62 vincristine doxorubicin 62 beam radiotherapy 62 candesartan cilexetil 62 mesalazine 62 PEGPH# 62 biliary tract cancer 62 chronic lymphocytic leukemia CLL 62 sotalol 62 verteporfin 62 Velcade bortezomib 62 intratumoral injection 62 #Gy 62 cranial irradiation 62 chemotherapeutic regimen 62 unresectable 62 alteplase 62 systemic antifungal 62 hypercalcemia 62 lanthanum carbonate 62 bolus dose 62 endocrine therapies 62 NOD SCID mice 62 alpha 2a 62 platinum refractory 62 Copegus ribavirin 62 pegylated interferon alpha 62 oral rivaroxaban 62 angiotensin converting enzyme inhibitors 62 VIDAZA 62 #mg QD [002] 62 basal cell carcinoma BCC 62 recombinant tissue plasminogen 62 darunavir ritonavir 62 remission induction 62 untreated multiple myeloma 62 invasive carcinomas 62 liver resection 62 tenofovir emtricitabine 62 CR CRu 62 hepatocellular carcinomas 62 milatuzumab 62 Bendamustine 62 ketorolac 62 Exemestane 62 fibrinolytic therapy 62 fluticasone 62 fumarate 62 aprepitant 62 CYPHER Stent 62 alefacept 62 intravitreal injection 62 oral antidiabetic 62 breast carcinoma 62 colon carcinoma 62 potent CYP#A# inhibitors 62 ribavirin therapy 62 progression TTP 62 taxane therapy 62 mg TID 62 angiotensin converting enzyme inhibitor 62 #mg/day [002] 62 TKI therapy 62 exemestane 62 Sandostatin LAR 62 cytopenias 62 immunoconjugate 62 potentially hepatotoxic 62 peg IFN 62 ARIMIDEX 62 selective agonist 62 cyclophosphamide doxorubicin 62 #mg/m# [002] 62 antiproliferative 62 mesalamine 62 ritonavir boosted atazanavir 62 Celecoxib 62 certolizumab 62 unfractionated heparin UFH 62 bolus injection 62 pancreatic adenocarcinoma 62 active comparator 62 olaparib 62 antiandrogens 62 pegylated interferon 62 #mg doses [002] 62 LVEF 62 PREZISTA r 62 FOLFOX regimen 62 TNF antagonist 62 transgene expression 62 radiofrequency ablation RFA 62 gliclazide 62 vWF 62 antiarrhythmic drug 62 pimecrolimus 62 heavily pretreated patients 62 BCG refractory 62 Imiquimod 62 Xanafide 62 Cloretazine 62 Xeloda ® 62 androgen suppression 62 L dopa 62 metformin sulfonylurea 62 q#h 62 Anthracycline 62 QT QTc 62 metastatic CRC 62 mecamylamine 62 raltegravir 62 dexrazoxane 62 PC3 cells 62 Gleevec imatinib mesylate 62 ß blockers 62 hepatoma 62 pimozide 62 LMWH 62 gemtuzumab ozogamicin 62 iniparib 62 recurrent metastatic 62 DMARD therapy 62 CTEPH 62 Azacitidine 62 antiangiogenic 62 insulin sensitizing 62 squamous histology 62 pegylated interferons 61 antidiabetic 61 antiarrhythmic drugs 61 3mg/kg 61 H. pylori eradication 61 enfuvirtide 61 FOLFOX4 alone 61 EGFR mutant 61 Vaprisol 61 meropenem 61 sarcomatoid 61 neoadjuvant treatment 61 rFVIIa 61 oxcarbazepine 61 CLA isomers 61 estrogen receptor progesterone receptor 61 palifermin 61 P = .# 61 Median PFS 61 ATACAND 61 betamethasone dipropionate 61 TIMP 1 61 stage IIIb IV 61 Pioglitazone 61 vinorelbine tartrate 61 malignant pleural mesothelioma 61 mg QD 61 glycoprotein IIb IIIa inhibitor 61 colorectal cancer liver metastases 61 medroxyprogesterone acetate 61 ug mL 61 antithrombotic therapy 61 Kinoid 61 ErbB2 positive 61 antiangiogenic therapy 61 liposomal amphotericin B 61 Xelox 61 ceftazidime 61 brain metastases 61 eribulin mesylate 61 mycophenolate 61 clotrimazole 61 leukemia CLL 61 fluticasone propionate 61 interferon IFN 61 peritoneal carcinomatosis 61 low dose ritonavir 61 cytotoxicity 61 Telmisartan 61 urothelial bladder cancer 61 VFEND 61 Neupogen ® 61 GP IIb IIIa inhibitors 61 Eli Lilly Gemzar 61 microg 61 SCIg 61 metastatic GIST 61 iNOS 61 metastatic gastric 61 darunavir r 61 gonadotropin releasing hormone 61 tumor regressions 61 induces apoptosis 61 inhaled corticosteroid ICS 61 electrical cardioversion 61 epirubicin cisplatin 61 ZD# [001] 61 ALA PDT 61 Radiofrequency ablation 61 antitumor effects 61 epoetin beta 61 pegIFN 61 mycophenolic acid 61 Bosutinib 61 nephrotoxicity 61 dose clopidogrel 61 chemotherapy regimen 61 EGFR TKIs 61 coadministration 61 ZOLINZA 61 sargramostim 61 Gemzar gemcitabine 61 TIMP 61 gadobutrol 61 mg qd 61 flavopiridol 61 liposomal formulation 61 TNF alpha inhibitor 61 Decitabine 61 ASCT 61 relapsing multiple sclerosis 61 WBRT 61 mg/m2/day 61 salpingo oophorectomy 61 Vorinostat 61 neutropaenia 61 anastrazole 61 induced apoptosis 61 baminercept 61 bexarotene 61 Carvedilol 61 Zoledronic acid 61 Adriamycin 61 camptothecin 61 carbidopa levodopa 61 fludarabine cyclophosphamide 61 androgen independent 61 lanreotide 61 axitinib 61 nucleoside analogs 61 Zorbtive TM 61 etanercept 61 variceal hemorrhage 61 Ceplene/IL-2 61 durable remissions 61 colorectal adenoma 61 ALGRX 61 LV ejection fraction 61 terfenadine 61 subcutaneous SC 61 rhEPO 61 microtubule inhibitor 61 liver metastases 61 intradermal injection 61 Vincristine 61 Interferon alpha 61 #mg dose [001] 61 mcg QD 61 estrogen receptor antagonist 61 PEGINTRON TM 61 hormone LHRH 61 CAELYX 61 Pegasys ® 61 splenectomized patients 61 amoxicillin clavulanate 61 timepoints 61 Surgical resection 61 lytic 61 mg BID 61 EGFR tyrosine kinase inhibitor 61 orthotopic 61 5HT 61 Telintra 61 thalidomide dexamethasone 61 GSTP1 61 drug zotarolimus 61 FIRMAGON 61 taxanes 61 curative resection 61 anthracyclines taxanes 61 doxazosin 61 fluticasone propionate FP 61 mirtazapine 61 Gemzar ® 61 VEGF receptor 61 raloxifene Evista 61 IGFBP 3 61 IL 1ß 61 KRAS mutations occur 61 Ranibizumab 61 myocardial reperfusion 61 intravenous dosing 61 5-fluorouracil/leucovorin 61 dosing frequency